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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 46, 2017 - Issue 5
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Original Articles

Th17-Inducing Conditions Lead to in vitro Activation of Both Th17 and Th1 Responses in Behcet’s Disease

Rabia DenizDepartment of Internal Medicine, School of Medicine, Marmara University, Istanbul, TurkeyCorrespondence[email protected]
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,
Aysın Tulunay-VirlanDepartment of Immunology, School of Medicine, Marmara University, Istanbul, TurkeyView further author information
,
Filiz Ture OzdemirDepartment of Immunology, School of Medicine, Marmara University, Istanbul, TurkeyView further author information
,
Ali Ugur UnalDivision of Rheumatology, School of Medicine, Marmara University, Istanbul, TurkeyView further author information
,
Gulsen OzenDivision of Rheumatology, School of Medicine, Marmara University, Istanbul, TurkeyView further author information
,
Fatma Alibaz-OnerDivision of Rheumatology, School of Medicine, Marmara University, Istanbul, TurkeyView further author information
,
Imren Aydin-TatliDepartment of Immunology, School of Medicine, Marmara University, Istanbul, TurkeyView further author information
,
Gonca MumcuFaculty of Health Science, Department of Health Informatics and Technologies, School of Medicine, Marmara University, Istanbul, TurkeyView further author information
,
Tulin ErgunDepartment of Dermatology, School of Medicine, Marmara University, Istanbul, TurkeyView further author information
&
Haner DireskeneliDivision of Rheumatology, School of Medicine, Marmara University, Istanbul, TurkeyView further author information
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Pages 518-525 | Published online: 17 Apr 2017

References

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  • Direskeneli H, Eksioglu-Demiralp E, Kibaroglu A, et al. 1999. Oligoclonal T cell expansions in patients with Behcet’s disease. Clin Exp Immunol, 117, 166–170.
  • Direskeneli H, Fujita H, Akdis CA. 2011. Regulation of TH17 and regulatory T cells in patients with Behcet disease. J Allergy Clin Immunol, 128, 665–666.
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  • Shimizu J, Takai K, Fujiwara N, et al. 2012. Excessive CD4+ T cells co-expressing interleukin-17 and interferon-gamma in patients with Behcet’s disease. Clin Exp Immunol, 168, 68–74.
  • Sugita S, Kawazoe Y, Imai A, et al. 2012. Inhibition of Th17 differentiation by anti-TNF-alpha therapy in uveitis patients with Behcet’s disease. Arthritis Res Ther, 14, R99.
  • Sutton CE, Mielke LA. 2012. Mills KH. IL-17-producing gammadelta T cells and innate lymphoid cells. Eur J Immunol, 42, 2221–2231.
  • Teunissen MB, Yeremenko NG, Baeten DL, et al. 2014. The IL-17A-producing CD8+ T-cell population in psoriatic lesional skin comprises mucosa-associated invariant T cells and conventional T cells. J Invest Dermatol, 134, 2898–2907.

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