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Immunological Investigations
A Journal of Molecular and Cellular Immunology
Volume 46, 2017 - Issue 6
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Original Articles

Role of Different CD40 Polymorphisms in Graves’ Disease and Hashimoto’s Thyroiditis

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References

  • Antonelli A, Ferrari SM, Corrado A, et al. (2015). Autoimmune thyroid disorders. Autoimmun Rev, 14, 174–80.
  • Antonelli A, Ferrari SM, Giuggioli D, et al. (2014). Chemokine (C-X-C motif) ligand (CXCL)10 in autoimmune diseases. Autoimmun Rev, 13, 272–80.
  • Armitage RJ, Fanslow WC, Strockbine L, et al. (1992). Molecular and biological characterization of a murine ligand for CD40. Nature, 357, 80–82.
  • Brix TH, Kyvik KO, Christensen K, Hegedus L. (2001). Evidence for a major role of heredity in Graves’ disease: a population-based study of two Danish twin cohorts. J Clin Endocrinol Metab, 86, 930–34.
  • Clark EA, Ledbetter JA. (2012). Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50. Proc. Natl. Acad. Sci. 1986. 83: 4494-4498. J Immunol, 188, 4130–34.
  • Guo H, Xu B, Yang X, et al. (2014). A high frequency of peripheral blood NKG2D+NK and NKT cells in euthyroid patients with new onset hashimoto’s thyroiditis–a pilot study. Immunol Invest, 43, 312–23.
  • Heward JM, Simmonds MJ, Carr-Smith J, et al. (2004). A single nucleotide polymorphism in the CD40 gene on chromosome 20q (GD-2) provides no evidence for susceptibility to Graves’ disease in UK Caucasians. Clin Endocrinol (Oxf), 61, 269–72.
  • Houston FA, Wilson V, Jennings CE, et al. (2004). Role of the CD40 locus in Graves’ disease. Thyroid, 14, 506–09.
  • Hsiao JY, Tien KJ, Hsiao CT, Hsieh MC. (2008). A C/T polymorphism in CD40 gene is not associated with susceptibility and phenotype of Graves’ disease in Taiwanese. Endocr J, 55, 477–84.
  • Huber AK, Finkelman FD, Li CW, et al. (2012). Genetically driven target tissue overexpression of CD40: a novel mechanism in autoimmune disease. J Immunol, 189, 3043–53.
  • Inoue N, Watanabe M, Yamada H, et al. (2012). Associations between autoimmune thyroid disease prognosis and functional polymorphisms of susceptibility genes, CTLA4, PTPN22, CD40, FCRL3, and ZFAT, previously revealed in genome-wide association studies. J Clin Immunol, 32, 1243–52.
  • Jacobson EM, Concepcion E, Oashi T, Tomer Y. (2005). A Graves’ disease-associated Kozak sequence single-nucleotide polymorphism enhances the efficiency of CD40 gene translation: a case for translational pathophysiology. Endocrinology, 146, 2684–91.
  • Jacobson EM, Tomer Y. (2007). The CD40, CTLA-4, thyroglobulin, TSH receptor, and PTPN22 gene quintet and its contribution to thyroid autoimmunity: back to the future. J Autoimmun, 28, 85–98.
  • Kim TY, Park YJ, Hwang JK, et al. (2003). A C/T polymorphism in the 5ʹ-untranslated region of the CD40 gene is associated with Graves’ disease in Koreans. Thyroid, 13, 919–25.
  • Kozak M. (1999). Initiation of translation in prokaryotes and eukaryotes. Gene, 234, 187–208.
  • Li M, Sun H, Liu S, et al. (2012). CD40 C/T-1 polymorphism plays different roles in Graves’ disease and Hashimoto’s thyroiditis: a meta-analysis. Endocr J, 59, 1041–50.
  • Locksley RM, Killeen N, Lenardo MJ. (2001). The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell, 104, 487–501.
  • Metcalfe RA, McIntosh RS, Marelli-Berg F, et al. (1998). Detection of CD40 on human thyroid follicular cells: analysis of expression and function. J Clin Endocrinol Metab, 83, 1268–74.
  • Mysliwiec J, Oklota M, Nikolajuk A, et al. (2007). Serum CD40/CD40L system in Graves’ disease and Hashimoto’s thyroiditis related to soluble Fas, FasL and humoral markers of autoimmune response. Immunol Invest, 36, 247–57.
  • Smith TJ, Sciaky D, Phipps RP, Jennings TA. (1999). CD40 expression in human thyroid tissue: evidence for involvement of multiple cell types in autoimmune and neoplastic diseases. Thyroid, 9, 749–55.
  • Taylor JC, Gough SC, Hunt PJ, et al. (2006). A genome-wide screen in 1119 relative pairs with autoimmune thyroid disease. J Clin Endocrinol Metab, 91, 646–53.
  • Tomer Y. (2010). Genetic susceptibility to autoimmune thyroid disease: past, present, and future. Thyroid, 20, 715–25.
  • Tomer Y. (2014). Mechanisms of autoimmune thyroid diseases: from genetics to epigenetics. Annu Rev Pathol, 9, 147–56.
  • Tomer Y, Concepcion E, Greenberg DA. (2002). A C/T single-nucleotide polymorphism in the region of the CD40 gene is associated with Graves’ disease. Thyroid, 12, 1129–35.
  • Tomer Y, Davies TF. (2003). Searching for the autoimmune thyroid disease susceptibility genes: from gene mapping to gene function. Endocr Rev, 24, 694–717.
  • Tomer Y, Davies TF, Greenberg DA. (2005). What is the contribution of a Kozak SNP in the CD40 gene to Graves’ disease? Clin Endocrinol (Oxf), 62, 258.
  • Tomer Y, Huber A. (2009). The etiology of autoimmune thyroid disease: a story of genes and environment. J Autoimmun, 32, 231–39.
  • Yang J, Qin Q, Yan N, et al. (2012). CD40 C/T(−1) and CTLA-4 A/G(49) SNPs are associated with autoimmune thyroid diseases in the Chinese population. Endocrine, 41, 111–15.

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