47
Views
44
CrossRef citations to date
0
Altmetric
Research Article

BENCH TO BEDSIDE: NEW APPROACHES TO THE IMMUNOTHERAPY OF UVEITIC DISEASE

Pages 273-289 | Published online: 03 Aug 2009

  • R. Nussenblatt, K. Mittal, S. Ryan, W. Green, and A. Maumenee, Birdshot retinochoroidopathy-An association with HAL-A29 and immune responsiveness to retinal S-antigen. Am. J. Ophthalmol., 94: 147-158, 1982.
  • D. Jabs, J. Rosenbaum, C. Foster, G. Holland, G. Jafee, J. Louie, R. Nussenblatt, E. Stiehm, H. Tessler, R. VanGelder, S. Whitcup, and D. Yocum, Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders. Am. J. Ophthalmol., 130: 492-513, 2000.
  • P. Brandtzaeg, Development and basic mechanisms of human gut immunity. Nutr. Rev., 56: S5-S18, 1998.
  • G. Macfarlaneand S. Macfarlane, Human colonic microbiota: Ecology, physiology and metabolic potential of intestinal bacteria. Scand. J. Gastroenterol. Suppl., 222: 3-9, 1997.
  • C. Nagler-Anderson, L. Bober, M. Robinson, G. Siskind, and F. Thorbeke, Suppression of type II collagen-induced arthritis by intragastric administration of soluble type II collagen. Proc. Natl. Acad. Sci. USA, 83: 7443-7446, 1986.
  • A. Besredka, De l'anaphylaxie. Sixième memoire de l'anaphylaxie lactique. Ann. Inst. Pasteur, 23: 166-174, 1909.
  • M. Chase, Inhibition of experimental drug allergy by prior feeding of the sensitizing agent. Proc. Soc. Exp. Biol. Med., 61: 257-259, 1946.
  • D. Bitarand C. Whitacre, Suppression of experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein. Cell. Immunol., 112: 364-370, 1988.
  • P. Higginsand H. Weiner, Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein and its fragments. J. Immunol., 140: 440-445, 1988.
  • H. Weiner, Oral tolerance: Immune mechanisms and treatment of autoimmune diseases. Immunol. Today, 18: 335-343, 1997.
  • R. Daynes, B. Araneo, T. Dowell, K. Huang, and D. Dudley, Regulation of murien lymphokine production in vivo. III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function. J. Exp. Med., 171(4): 979-996, 1990.
  • J. Benson, K. Campbell, Z. Guan, I. Gienapp, S. Stuckman, T. Forsthuber, and C. Whitacre, T-cell activation and receptor downmodulation precede deletion induced by mucosally administered antigen. J. Clin. Invest., 106(8): 1031-1038, 2000.
  • R. Nussenblatt, R. Caspi, R. Mahdi, C.-C. Chan, F. Roberge, O. Lider, and H. Weiner, Inhibition of S-antigen induced experimental autoimmune uveoretinitis by oral induction of tolerance with S-antigen. J. Immunol., 144(5): 1689-1695, 1990.
  • P. Silver, L.S. Rizzo, C.-C. Chan, B. Wiggert, R. Nussenblatt, and R. Caspi, Heterologous epitopes of IRBP protect against autoimmune uveitis induced by the autologous epitope. J. Neuroimmunol., 88: 128-136, 1998.
  • S. Thurau, C.-C. Chan, R. Nussenblatt, and R. Caspi, Oral tolerance in a murine model of relapsing experimental autoimmune uveoretinitis (EAU): Induction of protective tolerance in primed animals. Clin. Exp. Immunol., 109(2): 370-376, 1997.
  • L. Rizzo, R. Morawetz, N. Miller-Rivero, R. Choi, B. Wiggert, C.-C. Chan, H. Morse, R. Nussenblatt, and R. Caspi, IL-4 and IL-10 are both required for the induction of oral tolerance. J. Immunol., 162: 2613-2622, 1999.
  • L. Rizzo, N. Miller-Rivero, C.-C. Chan, B. Wiggert, R. Nussenblatt, and R. Caspi, Interleukin-2 treatment potentiates induction of oral tolerance in a murine model of autoimmunity. J. Clin. Invest., 94(4): 1668-1672, 1994.
  • R. Nussenblatt, I. Gery, H. Weiner, F. Ferris, J. Shiloach, N. Remaley, C. Perry, R. Caspi, D. Hafler, C. Foster, and S. Whitcup, Treatment of uveitis by oral administration of retinal antigens: Results of a phase I/II randomized masked trial. Am. J. Ophthalmol., 123(5): 583-592, 1997.
  • J. Benson, S. Stuckman, K. Cox, R. Wardrop, I. Gienapp, A. Cross, J. Trotter, and C. Whitacre, Oral administration of myelin basic protein is superior to myelin in suppressing established relapsing experimental autoimmune encephalomyelitis. J. Immunol, 162(10): 6247-6254, 1999.
  • H. Weiner, H.G. Mackin, M. Matsui, E. Orav, S. Khoury, D. Dawson, and D. Hafler, Double-blind pilot trial of oral tolerization with myelin antigens in multiple sclerosis. Science, 259: 1321-1324, 1993.
  • R. Caspi, F. Roberge, C. McAllister, M. El-Saied, T. Kuwabara, I. Gery, E. Hanna, and R. Nussenblatt, T-cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat. J. Immunol., 136: 928-933, 1986.
  • R.B. Nussenblatt, M.M. Rodrigues, W.B. Wacker, S.J. Cevario, M.C. SalinasCarmona, and I. Gery, Cyclosporin A: Inhibition of experimental autoimmune uveitis in Lewis rats. J. Clin. Invest., 67: 1228-1231, 1981.
  • R.B. Nussenblatt, A.G. Palestine, A.H. Rook, and I. Scher, Cyclosporine therapy for intra-ocular inflammatory disease. Lancet, ii: 235-238, 1983.
  • C. Queen, W. Schneider, H. Selick, et al., A humanized antibody that binds to the interleukin 2 receptor. Proc. Natl. Acad. Sci. USA, 86: 10029-10033, 1989.
  • M. Reed, M. Shapiro, T. Strom, et al., Prolongation of primate renal allograft survival by anti-Tac, an anti-human IL-2 receptor monoclonal antibody. Transplantation, 47: 55-59, 1989.
  • P.J. Brown, G. Parenteau, F. Dirbas, et al., Anti-Tac-H, a humanized antibody to the Interleukin 2 receptor, prolongs primate cardiac allograft survival. Proc. Natl. Acad. Sci. USA, 88: 2663-2667, 1991.
  • P. Herve, J. Wijdenes, J. Bergerat, et al., Treatment of corticosteroid resistant acute graft-versus-host disease by in vivo administration of anti-interleukin-2 receptor monoclonal antibody (B-B10). Blood, 75: 1017-1023, 1990.
  • F. Vincenti, R. Kirkman, S. Light, G. Bumgardner, M. Pescovitz, H. P, J. Neylan, A. Wilkinson, H. Ekberg, R. Gaston, L. Backman, J. Burdick, and for the Daclizumab Triple Therapy Study Group., Interleukin-2-receptor blockade with Daclizumab to prevent acute rejection in renal transplantation. N. Engl. J. Med., 338: 161-165, 1998.
  • Y. Guex-Crosier, J. Raber, C.-C. Chan, M. Knete, J. Benichou, R. Pilsen, J. Kerwin, T. Waldmann, J. Hakimi, and F. Roberge, Humanized antibodies against the alphachain of the IL-2 receptor and against the beta-chain shared by the IL-2 and IL-15 receptors in a monkey uveitis model of autoimmune diseases. J. Immunol., 158(1): 452-458, 1997.
  • H. BehU00E7et, Über Rezide, Viereude, Aphthose, durchein Virus verursache Geshwure am Mund, am Auge, und audeu Genitalien. Dermatol. Wochenschr., 46: 414-419, 1937.
  • Behçet's Disease Research Committee, Clinical research section recommendations. Jpn. J. Ophthalmol., 18: 291-294, 1974.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.