The Biological Role of Dectin-1 in Immune Response

REFERENCES

• C.A. Janeway, Jr. The immune system evolved to discriminate infectious nonself from noninfectious self, Immunol. Today, 13: 11–16, 1992.
   PubMedGoogle Scholar
• C.A. Janeway, Jr. and R. Medzhitov, Innate immune recognition, Annu. Rev. Immunol, 20: 197–216, 2002.
   PubMed Web of Science ®Google Scholar
• G.D. Brown and S. Gordon, Immune recognition. A new receptor for beta-glucans, Nature, 413: 36–37, 2001.
   PubMed Web of Science ®Google Scholar
• A. Pearson, A. Lux, and M. Krieger, Expression cloning of dSR-CI, a class C macrophage-specific scavenger receptor from Drosophila melanogaster. Proc. Natl. Acad. Sci. U. S. A., 92: 4056–4060, 1995.
   Google Scholar
• G.D. Ross, J.A. Cain, and P.J. Lachmann, Membrane complement receptor type three (CR3) has lectin-like properties analogous to bovine conglutinin as functions as a receptor for zymosan and rabbit erythrocytes as well as a receptor for iC3b, J. Immunol., 134: 3307–3315, 1985.
   PubMed Web of Science ®Google Scholar
• J.W. Zimmerman, et al., A novel carbohydrate-glycosphingolipid interaction between a beta-(1-3)-glucan immunomodulator, PGG-glucan, and lactosylceramide of human leukocytes, J. Biol. Chem., 273: 22014–22020, 1998.
   PubMed Web of Science ®Google Scholar
• J. Herre, et al., Dectin-1 uses novel mechanisms for yeast phagocytosis in macrophages, Blood, 104: 4038–4045, 2004.
   PubMedGoogle Scholar
• F. Grunebach, et al., Molecular and functional characterization of human Dectin-1, Exp. Hematol., 30: 1309–1315, 2002.
   PubMed Web of Science ®Google Scholar
• K. Ariizumi, et al., Cloning of a second dendritic cell-associated C-type lectin (dectin-2) and its alternatively spliced isoforms, J. Biol. Chem., 275: 11957–11963, 2000.
   Google Scholar
• K. Ariizumi, et al., Identification of a novel, dendritic cell-associated molecule, dectin-1, by subtractive cDNA cloning, J. Biol. Chem., 275: 20157–20167, 2000.
   PubMed Web of Science ®Google Scholar
• K. Sato, et al., Dectin-2 is a pattern recognition receptor for fungi that couples with the Fc receptor gamma chain to induce innate immune responses, J. Biol. Chem., 281: 38854–38866, 2006.
   PubMed Web of Science ®Google Scholar
• K. Yokota, et al., Identification of a human homologue of the dendritic cell-associated C-type lectin-1, dectin-1, Gene, 272: 51–60, 2001.
   PubMed Web of Science ®Google Scholar
• T.J. Olynych, D.L. Jakeman, and J.S. Marshall, Fungal zymosan induces leukotriene production by human mast cells through a dectin-1-dependent mechanism, J. Allergy Clin. Immunol., 118: 837–843, 2006.
   PubMed Web of Science ®Google Scholar
• P.R. Taylor, et al., The role of SIGNR1 and the beta-glucan receptor (dectin-1) in the nonopsonic recognition of yeast by specific macrophages, J. Immunol., 172: 1157–1162, 2004.
   PubMed Web of Science ®Google Scholar
• P.R. Taylor, et al., The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages, J. Immunol., 169: 3876–3882, 2002.
   PubMed Web of Science ®Google Scholar
• S.E. Heinsbroek, et al., Expression of functionally different dectin-1 isoforms by murine macrophages, J. Immunol., 176: 5513–5518, 2006.
   PubMedGoogle Scholar
• J. Xie, et al., Human Dectin-1 isoform E is a cytoplasmic protein and interacts with RanBPM, Biochem. Biophys. Res. Commun., 347: 1067–1073, 2006.
   Google Scholar
• P.R. Taylor, et al., Dectin-1 is required for beta-glucan recognition and control of fungal infection, Nat. Immunol., 8: 31–38, 2007.
   PubMed Web of Science ®Google Scholar
• H.S. Goodridge, R.M. Simmons, and D.M. Underhill, Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells, J. Immunol., 178: 3107–3115, 2007.
   PubMed Web of Science ®Google Scholar
• C. Dostert and J. Tschopp, DEteCTINg fungal pathogens, Nat. Immunol., 8: 17–18, 2007.
   Google Scholar
• S. Saijo, et al., Dectin-1 is required for host defense against Pneumocystis carinii but not against Candida albicans, Nat. Immunol., 8: 39–46, 2007.
   PubMed Web of Science ®Google Scholar
• C. Steele, et al., The beta-glucan receptor dectin-1 recognizes specific morphologies of Aspergillus fumigatus, PLoS Pathog, 1: e42, 2005.
   Google Scholar
• L. Romani, Immunity to fungal infections, Nat. Rev. Immunol., 4: 1–23, 2004.
   PubMed Web of Science ®Google Scholar
• T.M. Hohl, et al., Aspergillus fumigatus triggers inflammatory responses by stage-specific beta-glucan display, PLoS Pathog, 1: e30, 2005.
   Google Scholar
• C. Steele, et al., Alveolar macrophage-mediated killing of Pneumocystis carinii f. sp. muris involves molecular recognition by the Dectin-1 beta-glucan receptor, J. Exp. Med., 198: 1677–1688, 2003.
   PubMed Web of Science ®Google Scholar
• G.D. Brown and S. Gordon, Immune recognition of fungal beta-glucans, Cell. Microbiol., 7: 471–479, 2005.
   PubMed Web of Science ®Google Scholar
• A.S. Palma, et al., Ligands for the beta-glucan receptor, Dectin-1, assigned using “designer” microarrays of oligosaccharide probes (neoglycolipids) generated from glucan polysaccharides, J. Biol. Chem., 281: 5771–5779, 2006.
   PubMed Web of Science ®Google Scholar
• G.D. Brown, et al., Dectin-1 is a major beta-glucan receptor on macrophages, J. Exp. Med., 196: 407–412, 2002.
   PubMed Web of Science ®Google Scholar
• G.D. Brown, et al., Dectin-1 mediates the biological effects of beta-glucans, J. Exp. Med., 197: 1119–1124, 2003.
   PubMed Web of Science ®Google Scholar
• Y. Adachi, et al., Characterization of beta-glucan recognition site on C-type lectin, dectin 1, Infect. Immun., 72: 4159–4171, 2004.
   PubMed Web of Science ®Google Scholar
• S.E. Evans, et al., Pneumocystis cell wall beta-glucans stimulate alveolar epithelial cell chemokine generation through nuclear factor-kappaB-dependent mechanisms, Am. J. Respir. Cell. Mol. Biol., 32: 490–497, 2005.
   PubMed Web of Science ®Google Scholar
• E.M. Carmona, et al., Pneumocystis cell wall beta-glucans induce dendritic cell costimulatory molecule expression and inflammatory activation through a Fas-Fas ligand mechanism, J. Immunol., 177: 459–467, 2006.
   Google Scholar
• B.N. Gantner, R.M. Simmons, and D.M. Underhill, Dectin-1 mediates macrophage recognition of Candida albicans yeast but not filaments, Embo. J., 24: 1277–1286, 2005.
   PubMed Web of Science ®Google Scholar
• C.A. Rappleye, L.G. Eissenberg, and W.E. Goldman, Histoplasma capsulatum alpha-(13)-glucan blocks innate immune recognition by the beta-glucan receptor, Proc. Natl. Acad. Sci. U. S. A., 104: 1366–1370, 2007.
   Google Scholar
• F. McCann, et al., Macrophage internalization of fungal beta-glucans is not necessary for initiation of related inflammatory responses, Infect. Immun., 73: 6340–6349, 2005.
   PubMed Web of Science ®Google Scholar
• K.M. Dennehy and G.D. Brown, The role of the {beta}-glucan receptor Dectin-1 in control of fungal infection, J. Leukoc. Biol., 2007.
   Google Scholar
• B.N. Gantner, et al., Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2, J. Exp. Med., 197: 1107–1117, 2003.
   PubMed Web of Science ®Google Scholar
• H. Yoshitomi, et al., A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice, J. Exp. Med., 201: 949–960, 2005.
   PubMed Web of Science ®Google Scholar
• S. Olsson and R. Sundler, The macrophage beta-glucan receptor mediates arachidonate release induced by zymosan: essential role for Src family kinases, Mol. Immunol., 44: 1509–1515, 2007.
   Google Scholar
• S. Suram, et al., Regulation of cytosolic phospholipase A2 activation and cyclooxygenase 2 expression in macrophages by the beta-glucan receptor, J. Biol. Chem., 281: 5506–5514, 2006.
   PubMed Web of Science ®Google Scholar
• J. Herre, S. Gordon, and G.D. Brown, Dectin-1 and its role in the recognition of beta-glucans by macrophages, Mol. Immunol., 40: 869–876, 2004.
   PubMed Web of Science ®Google Scholar
• S. Dillon, et al., Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance, J. Clin. Invest., 116: 916–928, 2006.
   PubMed Web of Science ®Google Scholar
• C. Sedlik, et al., A critical role for Syk protein tyrosine kinase in Fc receptor-mediated antigen presentation and induction of dendritic cell maturation, J. Immunol., 170: 846–852, 2003.
   PubMed Web of Science ®Google Scholar
• J.A. Willment, et al., Dectin-1 expression and function are enhanced on alternatively activated and GM-CSF-treated macrophages and are negatively regulated by IL-10, dexamethasone, and lipopolysaccharide, J. Immunol., 171: 4569–4573, 2003.
   PubMed Web of Science ®Google Scholar
• F. Meyer. Wentrup, , et al., Dectin-1 interaction with tetraspanin CD37 inhibits IL-6 production, J. Immunol., 178: 154–162, 2007.
   Google Scholar
• A.B. van Spriel, et al., A regulatory role for CD37 in T cell proliferation, J. Immunol., 172: 2953–2961, 2004.
   PubMed Web of Science ®Google Scholar
• Y. Kato, Y. Adachi, and N. Ohno, Contribution of N-linked oligosaccharides to the expression and functions of beta-glucan receptor, Dectin-1, Biol. Pharm. Bull., 29: 1580–1586, 2006.
   PubMed Web of Science ®Google Scholar
• G.L. Fuller, et al., The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade, J. Biol. Chem., 282: 12397–123409, 2007.
   PubMed Web of Science ®Google Scholar
• M.S. Lee and Y.J. Kim, Signaling pathways downstream of pattern-recognition receptors and their cross talk, Annu. Rev. Biochem., 2007.
   Google Scholar
• F. Meyer-Wentrup, et al., “Sweet talk”: Closing in on C type lectin signaling, Immunity, 22(4): 399–400, 2005.
   Google Scholar
• G.D. Brown, Dectin-1: a signalling non-TLR pattern-recognition receptor, Nat. Rev. Immunol., 6: 33–43, 2006.
   PubMed Web of Science ®Google Scholar
• S. Gordon, Pattern recognition receptors: Doubling up for the innate immune response, Cell., 111: 927–930, 2002.
   PubMed Web of Science ®Google Scholar
• D.M. Underhill, et al., Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production, Blood, 106: 2543–2550, 2005.
   PubMed Web of Science ®Google Scholar
• S.N. Diniz, et al., PTX3 function as an opsonin for the dectin-1-dependent internalization of zymosan by macrophages, J. Leukoc. Biol., 75: 649–656, 2004.
   PubMed Web of Science ®Google Scholar
• M. Yadav and J.S. Schorey, The beta-glucan receptor dectin-1 functions together with TLR2 to mediate macrophage activation by mycobacteria, Blood, 108: 3168–3175, 2006.
   PubMed Web of Science ®Google Scholar
• K. Luther, et al., Phagocytosis of Aspergillus fumigatus conidia by murine macrophages involves recognition by the dectin-1 beta-glucan receptor and Toll-like receptor 2, Cell. Microbiol., 9: 368–381, 2007.
   PubMed Web of Science ®Google Scholar
• M.G. Netea, et al., Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors, J. Clin. Invest., 116: 1642–1650, 2006.
   PubMed Web of Science ®Google Scholar
• S. Viriyakosol, et al., Innate immunity to the pathogenic fungus Coccidioides posadasii is dependent on Toll-like receptor 2 and Dectin-1, Infect. Immun., 73: 1553–1560, 2005.
   PubMed Web of Science ®Google Scholar
• K.A. Marr, et al., Differential role of MyD88 in macrophage-mediated responses to opportunistic fungal pathogens, Infect. Immun., 71: 5280–5286, 2003.
   PubMed Web of Science ®Google Scholar
• L.M. Graham, et al., Soluble Dectin-1 as a tool to detect beta-glucans, J. Immunol. Methods, 314: 164–169, 2006.
   PubMed Web of Science ®Google Scholar
• R.W. Carter, et al., Preferential induction of CD4 + T cell responses through in vivo targeting of antigen to dendritic cell-associated C-type lectin-1, J. Immunol., 177: 2276–2284, 2006.
   PubMed Web of Science ®Google Scholar
• M.C. Milone and P. Fitzgerald-Bocarsly, The mannose receptor mediates induction of IFN-alpha in peripheral blood dendritic cells by enveloped RNA and DNA viruses, J. Immunol., 161: 2391–2399, 1998.
   PubMed Web of Science ®Google Scholar
• C. Patrick, J.L.M. Reading, and E. Margot Anders, Involvement of the mannose receptor in infection of macrophages by influenza virus, J. Virol., 74: 5190–5197, 2000.
   Google Scholar
• P.R. Taylor, L.M. -P., M. Stacey, H-H. Lin, G.D. Brown, and S. Gordon, Macrophage receptors and immune recognition, Annu. Rev. Immunol., 23: 901–944, 2005.
   PubMed Web of Science ®Google Scholar
• B.H. Teunis, S.J.v.V. Geijtenbeek, A. Engering, B. A. 't Hart, Y. van Kooyk, Self- and nonself-recognition by C-type lectins on dendritic cells, Annu. Rev. Immunol., 22: 33–54, 2004.
   Google Scholar