Short-term use of ceftriaxone sodium leads to intestinal barrier disruption and ultrastructural changes of kidney in SD rats

References

• Guo Y, Yang X, Qi Y, et al. Long-term use of ceftriaxone sodium induced changes in gut microbiota and immune system. Sci Rep. 2017;7:1. doi: 10.1038/srep43035.
   PubMedGoogle Scholar
• Li M, Liang P, Li Z, et al. Fecal microbiota transplantation and bacterial consortium transplantation have comparable effects on the re-establishment of mucosal barrier function in mice with intestinal dysbiosis. Front Microbiol. 2015;6:692. doi: 10.3389/fmicb.2015.00692.
   PubMed Web of Science ®Google Scholar
• Landman C, Quevrain E. Gut microbiota: description, role and pathophysiologic implications. Rev Med Interne. 2016;37(6):418–10. doi: 10.1016/j.revmed.2015.12.012.
   PubMed Web of Science ®Google Scholar
• Yang J, Lim SY, Ko YS, et al. Intestinal barrier disruption and dysregulated mucosal immunity contribute to kidney fibrosis in chronic kidney disease. Nephrol Dial Transplant. 2019;34(3):419–428. doi: 10.1093/ndt/gfy172.
   PubMed Web of Science ®Google Scholar
• Cosola C, Rocchetti MT, Sabatino A, et al. Microbiota issue in CKD: how promising are gut-targeted approaches? J Nephrol. 2019;32(1):27–37. doi: 10.1007/s40620-018-0516-0.
   PubMed Web of Science ®Google Scholar
• Rukavina Mikusic NL, Kouyoumdzian NM, Choi MR. Gut microbiota and chronic kidney disease: evidences and mechanisms that mediate a new communication in the gastrointestinal-renal axis. Pflugers Arch. 2020;472(3):303–320. doi: 10.1007/s00424-020-02352-x.
   PubMed Web of Science ®Google Scholar
• Majumder S, Pushpakumar S, Sen U. Dysbiosis in hypertension modulates kidney function through TLR4‐mediated gut barrier disruption. FASEB J. 2020;34(S1):1–1. doi: 10.1096/fasebj.2020.34.s1.04330.
   Google Scholar
• Basic M, Buettner M, Keubler LM, et al. Loss of CD14 leads to disturbed epithelial-B cell crosstalk and impairment of the intestinal barrier after E. coli nissle monoassociation. Sci Rep. 2018;8(1):719. doi: 10.1038/s41598-017-19062-7.
   PubMedGoogle Scholar
• Yang L, Wang Y, Nuerbiye A, et al. Effects of periostracum cicadae on cytokines and apoptosis regulatory proteins in an IgA nephropathy rat model. Int J Mol Sci. 2018;19(6):1599.
   Web of Science ®Google Scholar
• Wei L, Du Y, Jia L, et al. Therapeutic effects of FK506 on IgA nephropathy rat. Kidney Blood Press Res. 2017;42(6):983–998. doi: 10.1159/000485346.
   PubMed Web of Science ®Google Scholar
• Lu H, Chen LL, Jiang XY, et al. Temporal and spatial expression of podocyte-associated molecules are accompanied by proteinuria in IgA nephropathy rat model. Physiol Res. 2013;62(1):35–45. doi: 10.33549/physiolres.932380.
   PubMed Web of Science ®Google Scholar
• Luo X, Pan Z, Luo S, et al. Effects of ceftriaxone-induced intestinal dysbacteriosis on regulatory T cells validated by anaphylactic mice. Int Immunopharmacol. 2018;60:221–227. doi: 10.1016/j.intimp.2018.05.003.
   PubMed Web of Science ®Google Scholar
• Zou JN, Xiao J, Hu SS, et al. Toll-like receptor 4 signaling pathway in the protective effect of pioglitazone on experimental immunoglobulin a nephropathy. Chin Med J (Engl). 2017;130(8):906–913. doi: 10.4103/0366-6999.204101.
   PubMed Web of Science ®Google Scholar
• Li C, Che LH, Ji TF, et al. Effects of the TLR4 signaling pathway on apoptosis of neuronal cells in diabetes mellitus complicated with cerebral infarction in a rat model. Sci Rep. 2017;7:43834. doi: 10.1038/srep43834.
   PubMed Web of Science ®Google Scholar
• Domingo S, Sanchez Sanchez JJ. C. From the intestinal flora to the microbiome. Rev Esp Enferm Dig. 2018;110(1):51–56.
   Web of Science ®Google Scholar
• Zhou B, Yuan Y, Zhang S, et al. Intestinal flora and disease mutually shape the regional immune system in the intestinal tract. Front Immunol. 2020;11:575. doi: 10.3389/fimmu.2020.00575.
   PubMed Web of Science ®Google Scholar
• Lange K, Buerger M, Stallmach A, et al. Effects of antibiotics on gut microbiota. Dig Dis. 2016;34(3):260–268. doi: 10.1159/000443360.
   PubMed Web of Science ®Google Scholar
• Panda S, El Khader I, Casellas F, et al. Short-term effect of antibiotics on human gut microbiota. PLoS One. 2014;9(4):e95476. doi: 10.1371/journal.pone.0095476.
   PubMed Web of Science ®Google Scholar
• Blaser MJ. Our missing microbes: short-term antibiotic courses have long-term consequences. Cleve Clin J Med. 2018;85(12):928–930. doi: 10.3949/ccjm.85gr.18005.
   PubMed Web of Science ®Google Scholar
• Ettehad Marvasti F, Moshiri A, Taghavi MS, et al. The first report of differences in gut microbiota composition between obese and normal weight Iranian subjects. Iran Biomed J. 2020;24(3):148–154. doi: 10.29252/ibj.24.3.148.
   PubMedGoogle Scholar
• Amabebe E, Robert FO, Agbalalah T, et al. Microbial dysbiosis-induced obesity: role of gut microbiota in homoeostasis of energy metabolism. Br J Nutr. 2020;123(10):1127–1137. doi: 10.1017/S0007114520000380.
   PubMed Web of Science ®Google Scholar
• Danilova NA, Abdulkhakov SR, Grigoryeva TV, et al. Markers of dysbiosis in patients with ulcerative colitis and Crohn’s disease. Ter Arkh. 2019;91(4):17–24.
   PubMed Web of Science ®Google Scholar
• Guirro M, Costa A, Gual-Grau A, et al. Effects from diet-induced gut microbiota dysbiosis and obesity can be ameliorated by fecal microbiota transplantation: a multiomics approach. PLoS One. 2019;14(9):e0218143. doi: 10.1371/journal.pone.0218143.
   PubMed Web of Science ®Google Scholar
• Knoop KA, McDonald KG, McCrate S, et al. Microbial sensing by goblet cells controls immune surveillance of luminal antigens in the Colon. Mucosal Immunol. 2015;8(1):198–210. doi: 10.1038/mi.2014.58.
   PubMed Web of Science ®Google Scholar
• Knoop KA, Newberry RD. Goblet cells: multifaceted players in immunity at mucosal surfaces. Mucosal Immunol. 2018;11(6):1551–1557. doi: 10.1038/s41385-018-0039-y.
   PubMed Web of Science ®Google Scholar
• Imani Fooladi AA, Mousavi SF, Seghatoleslami S, et al. Toll-like receptors: role of inflammation and commensal bacteria. Inflamm Allergy Drug Targets. 2011;10(3):198–207. doi: 10.2174/187152811795564064.
   PubMedGoogle Scholar
• Mu C, Yang Y, Zhu W. Crosstalk between the immune receptors and gut microbiota. Curr Protein Pept Sci. 2015;16(7):622–631. doi: 10.2174/1389203716666150630134356.
   PubMed Web of Science ®Google Scholar
• Matsunaga N, Tsuchimori N, Matsumoto T, et al. TAK-242 (resatorvid), a small-molecule inhibitor of toll-like receptor (TLR) 4 signaling, binds selectively to TLR4 and interferes with interactions between TLR4 and its adaptor molecules. Mol Pharmacol. 2011;79(1):34–41. doi: 10.1124/mol.110.068064.
   PubMed Web of Science ®Google Scholar
• Samarpita S, Kim JY, Rasool MK, et al. Investigation of toll-like receptor (TLR) 4 inhibitor TAK-242 as a new potential anti-rheumatoid arthritis drug. Arthritis Res Ther. 2020;22(1):16. doi: 10.1186/s13075-020-2097-2.
   PubMed Web of Science ®Google Scholar
• Wei Z, Sun X, Xu Q, et al. TAK-242 suppresses lipopolysaccharide-induced inflammation in human coronary artery endothelial cells. Pharmazie. 2016;71(10):583–587.
   PubMed Web of Science ®Google Scholar
• Ikeda H, Sasaki M, Ishikawa A, et al. Interaction of toll-like receptors with bacterial components induces expression of CDX2 and MUC2 in rat biliary epithelium in vivo and in culture. Lab Invest. 2007;87(6):559–571. doi: 10.1038/labinvest.3700556.
   PubMed Web of Science ®Google Scholar
• Hu J, Luo H, Wang J, et al. Enteric dysbiosis-linked gut barrier disruption triggers early renal injury induced by chronic high salt feeding in mice. Exp Mol Med. 2017;49(8):e370. doi: 10.1038/emm.2017.122.
   PubMedGoogle Scholar
• Khoury T, Tzukert K, Abel R, et al. The gut-kidney axis in chronic renal failure: a new potential target for therapy. Hemodial Int. 2017;21(3):323–334. doi: 10.1111/hdi.12486.
   PubMed Web of Science ®Google Scholar
• Knauf F, Brewer JR, Flavell RA. Immunity, microbiota and kidney disease. Nat Rev Nephrol. 2019;15(5):263–274. doi: 10.1038/s41581-019-0118-7.
   PubMed Web of Science ®Google Scholar
• Anders HJ, Andersen K, Stecher B. The intestinal microbiota, a leaky gut, and abnormal immunity in kidney disease. Kidney Int. 2013;83(6):1010–1016. doi: 10.1038/ki.2012.440.
   PubMed Web of Science ®Google Scholar
• Yang X, Zhong H, Xu C, et al. Spotlights on antibiotic-induced acute kidney injury: the evidence to date. Iran J Kidney Dis. 2019;13(1):10–20.
   PubMed Web of Science ®Google Scholar