Association between monocyte-lymphocyte ratio and all-cause and cardiovascular mortality in patients with chronic kidney diseases: A data analysis from national health and nutrition examination survey (NHANES) 2003-2010

References

• Alwan A, Maclean DR, Riley LM, et al. Monitoring and surveillance of chronic non-communicable diseases: progress and capacity in high-burden countries. Lancet. 2010;376(9755):1–10. doi: 10.1016/s0140-6736(10)61853-3.
   PubMed Web of Science ®Google Scholar
• Anderson GF, Chu E. Expanding priorities–confronting chronic disease in countries with low income. N Engl J Med. 2007;356(3):209–211. doi: 10.1056/NEJMp068182.
   PubMed Web of Science ®Google Scholar
• Vanholder R, Massy Z, Argiles A, et al. Chronic kidney disease as cause of cardiovascular morbidity and mortality. Nephrol Dial Transplant. 2005;20(6):1048–1056. doi: 10.1093/ndt/gfh813.
   PubMed Web of Science ®Google Scholar
• Munoz Mendoza J, Isakova T, Cai X, et al. Inflammation and elevated levels of fibroblast growth factor 23 are independent risk factors for death in chronic kidney disease. Kidney Int. 2017;91(3):711–719. doi: 10.1016/j.kint.2016.10.021.
   PubMed Web of Science ®Google Scholar
• Zhang M, Wang K, Zheng H, et al. Monocyte lymphocyte ratio predicts the new-onset of chronic kidney disease: a cohort study. Clin Chim Acta. 2020;503:181–189. doi: 10.1016/j.cca.2019.11.021.
   PubMed Web of Science ®Google Scholar
• Xiang F, Chen R, Cao X, et al. Monocyte/lymphocyte ratio as a better predictor of cardiovascular and all-cause mortality in hemodialysis patients: a prospective cohort study. Hemodial Int. 2018;22(1):82–92. doi: 10.1111/hdi.12549.
   PubMed Web of Science ®Google Scholar
• Mureșan AV, Russu E, Arbănași EM, et al. The predictive value of NLR, MLR, and PLR in the outcome of end-stage kidney disease patients. Biomedicines. 2022;10(6):1272. doi: 10.3390/biomedicines10061272.
   PubMed Web of Science ®Google Scholar
• Qiu C, Liu S, Li X, et al. Prognostic value of monocyte-to-lymphocyte ratio for 90-day all-cause mortality in type 2 diabetes mellitus patients with chronic kidney disease. Sci Rep. 2023;13(1):13136. doi: 10.1038/s41598-023-40429-6.
   PubMed Web of Science ®Google Scholar
• Choi SH, Kim JH, Lim S, et al. Monocyte count as a ­predictor of cardiovascular mortality in older Korean people. Age Ageing. 2017;46(3):433–438. doi: 10.1093/ageing/afw226.
   PubMed Web of Science ®Google Scholar
• Swirski FK, Pittet MJ, Kircher MF, et al. Monocyte ­accumulation in mouse atherogenesis is progressive and proportional to extent of disease. Proc Natl Acad Sci U S A. 2006;103(27):10340–10345. doi: 10.1073/pnas.0604260103.
   PubMed Web of Science ®Google Scholar
• Ruparelia N, Godec J, Lee R, et al. Acute myocardial ­infarction activates distinct inflammation and proliferation pathways in circulating monocytes, prior to recruitment, and identified through conserved transcriptional responses in mice and humans. Eur Heart J. 2015;36(29):1923–1934. doi: 10.1093/eurheartj/ehv195.
   PubMed Web of Science ®Google Scholar
• Tsujioka H, Imanishi T, Ikejima H, et al. Impact of ­heterogeneity of human peripheral blood monocyte subsets on myocardial salvage in patients with primary acute myocardial infarction. J Am Coll Cardiol. 2009;54(2):130–138. doi: 10.1016/j.jacc.2009.04.021.
   PubMed Web of Science ®Google Scholar
• Ono K, Matsumori A, Furukawa Y, et al. Prevention of myocardial reperfusion injury in rats by an antibody against monocyte chemotactic and activating factor/monocyte chemoattractant protein-1. Lab Invest. 1999;79(2):195–203.
   PubMed Web of Science ®Google Scholar
• Hulsmans M, Sam F, Nahrendorf M. Monocyte and macrophage contributions to cardiac remodeling. J Mol Cell Cardiol. 2016;93:149–155. doi: 10.1016/j.yjmcc.2015.11.015.
   PubMed Web of Science ®Google Scholar
• Rogacev KS, Cremers B, Zawada AM, et al. CD14++CD16+ monocytes independently predict cardiovascular events: a cohort study of 951 patients referred for elective coronary angiography. J Am Coll Cardiol. 2012;60(16):1512–1520. doi: 10.1016/j.jacc.2012.07.019.
   PubMed Web of Science ®Google Scholar
• Barisione C, Garibaldi S, Ghigliotti G, et al. CD14CD16 monocyte subset levels in heart failure patients. Dis Markers. 2010;28(2):115–124. doi: 10.3233/dma-2010-0691.
   PubMed Web of Science ®Google Scholar
• Combadière C, Potteaux S, Rodero M, et al. Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6C(hi) and Ly6C(lo) monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice. Circulation. 2008;117(13):1649–1657. doi: 10.1161/circulationaha.107.745091.
   PubMed Web of Science ®Google Scholar
• Ramírez R, Carracedo J, Soriano S, et al. Stress-induced premature senescence in mononuclear cells from ­patients on long-term hemodialysis. Am J Kidney Dis. 2005;45(2):353–359. doi: 10.1053/j.ajkd.2004.10.022.
   PubMed Web of Science ®Google Scholar
• Heine GH, Ulrich C, Seibert E, et al. CD14(++)CD16+ monocytes but not total monocyte numbers predict cardiovascular events in dialysis patients. Kidney Int. 2008;73(5):622–629. doi: 10.1038/sj.ki.5002744.
   PubMed Web of Science ®Google Scholar
• Rogacev KS, Seiler S, Zawada AM, et al. CD14++CD16+ monocytes and cardiovascular outcome in patients with chronic kidney disease. Eur Heart J. 2011;32(1):84–92. doi: 10.1093/eurheartj/ehq371.
   PubMed Web of Science ®Google Scholar
• Rogacev KS, Ziegelin M, Ulrich C, et al. Haemodialysis-induced transient CD16+ monocytopenia and ­cardiovascular outcome. Nephrol Dial Transplant. 2009;24(11):3480–3486. doi: 10.1093/ndt/gfp287.
   PubMed Web of Science ®Google Scholar
• Núñez J, Miñana G, Bodí V, et al. Low lymphocyte count and cardiovascular diseases. Curr Med Chem. 2011;18(21):3226–3233. doi: 10.2174/092986711796391633.
   PubMed Web of Science ®Google Scholar
• Le Tulzo Y, Pangault C, Gacouin A, et al. Early circulating lymphocyte apoptosis in human septic shock is associated with poor outcome. Shock. 2002;18(6):487–494. doi: 10.1097/00024382-200212000-00001.
   PubMed Web of Science ®Google Scholar
• Ommen SR, Gibbons RJ, Hodge DO, et al. Usefulness of the lymphocyte concentration as a prognostic marker in coronary artery disease. Am J Cardiol. 1997;79(6):812–814. doi: 10.1016/s0002-9149(96)00878-8.
   PubMed Web of Science ®Google Scholar
• Levy WC, Mozaffarian D, Linker DT, et al. The Seattle heart failure model: prediction of survival in heart failure. Circulation. 2006;113(11):1424–1433. doi: 10.1161/circulationaha.105.584102.
   PubMed Web of Science ®Google Scholar
• Yücel H, Refiker Ege M, Zorlu A, et al. Lymphocytopenia is associated with poor NYHA functional class in chronic heart failure patients with reduced ejection fraction. Turk Kardiyol Dern Ars. 2015;43(5):427–433. doi: 10.5543/tkda.2015.89439.
   PubMedGoogle Scholar
• Winterberg PD, Robertson JM, Kelleman MS, et al. T cells play a causal role in diastolic dysfunction during uremic cardiomyopathy. J Am Soc Nephrol. 2019;30(3):407–420. doi: 10.1681/asn.2017101138.
   PubMed Web of Science ®Google Scholar
• Lin J, Tang B, He G, et al. B lymphocytes subpopulations are associated with cardiac remodeling in elderly patients with advanced chronic kidney disease. Exp Gerontol. 2022;163:111805. doi: 10.1016/j.exger.2022.111805.
   PubMed Web of Science ®Google Scholar
• Lin J, Tang W, Liu W, et al. Decreased B1 and B2 lymphocytes are associated with mortality in elderly ­patients with chronic kidney diseases. Front Med (Lausanne). 2020;7:75. doi: 10.3389/fmed.2020.00075.
   PubMed Web of Science ®Google Scholar
• Chen H, Li M, Liu L, et al. Monocyte/lymphocyte ratio is related to the severity of coronary artery disease and clinical outcome in patients with non-ST-elevation myocardial infarction. Medicine (Baltimore). 2019;98(26):e16267. doi: 10.1097/md.0000000000016267.
   PubMed Web of Science ®Google Scholar
• Fan Z, Ji H, Li Y, et al. Relationship between monocyte-to-lymphocyte ratio and coronary plaque vulnerability in patients with stable angina. Biomark Med. 2017;11(11):979–990. doi: 10.2217/bmm-2017-0235.
   PubMed Web of Science ®Google Scholar
• Silva N, Bettencourt P, Guimarães JT. The lymphocyte-to-monocyte ratio: an added value for death prediction in heart failure. Nutr Metab Cardiovasc Dis. 2015;25(11):1033–1040. doi: 10.1016/j.numecd.2015.07.004.
   PubMed Web of Science ®Google Scholar
• Gijsberts CM, Ellenbroek G, Ten Berg MJ, et al. Effect of monocyte-to-lymphocyte ratio on heart failure characteristics and hospitalizations in a coronary angiography cohort. Am J Cardiol. 2017;120(6):911–916. doi: 10.1016/j.amjcard.2017.06.020.
   PubMed Web of Science ®Google Scholar
• Welsh C, Welsh P, Mark PB, et al. Association of total and differential leukocyte counts with cardiovascular disease and mortality in the UK biobank. Arterioscler Thromb Vasc Biol. 2018;38(6):1415–1423. doi: 10.1161/atvbaha.118.310945.
   PubMed Web of Science ®Google Scholar
• Wang Q, Ma J, Jiang Z, et al. Association of lymphocyte-to-monocyte ratio with in-hospital and long-term major adverse cardiac and cerebrovascular events in patients with ST-elevated myocardial infarction. Medicine (Baltimore). 2017;96(34):e7897. doi: 10.1097/md.0000000000007897.
   PubMed Web of Science ®Google Scholar
• Agarwal R, Light RP. Patterns and prognostic value of total and differential leukocyte count in chronic kidney disease. Clin J Am Soc Nephrol. 2011;6(6):1393–1399. doi: 10.2215/cjn.10521110.
   PubMed Web of Science ®Google Scholar