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Pediatric Hematology and Oncology Volume 25, 2008 - Issue 2
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Case Reports

ANAPHYLACTOID REACTION TO HIGH-DOSE METHOTREXATE AND RE-ADMINISTRATION AFTER A SUCCESSFUL DESENSITIZATION

Teresa Caldeira Department of Paediatrics, Centro Hospitalar Vila Nova de Gaia, Vila Nova de Gaia, Portugal
,
Vitor Costa Department of Medical Oncology, Division of Paediatric Hematology/Oncology, Portuguese Institute of Oncology–Porto, Porto, Portugal
,
Isabel Silva Department of Medical Oncology, Division of Paediatric Hematology/Oncology, Portuguese Institute of Oncology–Porto, Porto, Portugal
,
Tereza Oliva Department of Medical Oncology, Division of Paediatric Hematology/Oncology, Portuguese Institute of Oncology–Porto, Porto, Portugal
&
Lucília Norton Department of Medical Oncology, Division of Paediatric Hematology/Oncology, Portuguese Institute of Oncology–Porto, Porto, Portugal
Pages 131-134 | Received 21 Jun 2007, Accepted 16 Oct 2007, Published online: 09 Jul 2009

REFERENCES

  • Whitehead V M, Shuter J J, Vuchich M J, et al. Accumulation of methotrexate and methotrexate polyglutamates in lymphoblasts and treatment outcome in children with B-progenitor-cell acute lymphoblastic leukaemia: a Pediatric Oncology Group study. Leukemia 2005; 19: 533–536
  • Devecioglu O, Biner B, Karabocuoglu M, Unuvar A, Agaoglu L. Systemic near-fatal anaphylactic reaction after intrathecal methotrexate administration. Med Pediatr Oncol 2000; 34: 151–152
  • Postovsky S, Elhasid R, Ben-Barak A, Levin K, Ben Arush M W. Allergic reaction to high-dose methotrexate. Med Pediatr Oncol 2000; 35: 131–132
  • MacGinnitie A J, Walensky L D, Turvey S E, et al. Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge. Pediatr Allergy Immunol 2003; 14: 409–411
  • Lobelle C, Lopez Rivas M, Barreiro J, Rodicio M, Couselo J M. Anaphylactic reaction to high-dose methotrexate. Pediatr Hematol Oncol 1995; 12: 213–214
  • Kohli A, Ferencz T M, Calderon J G. Readministration of high-dose methotrexate in a patient with suspected immediate hypersensitivity and T-cell acute lymphoblastic lymphoma. Allergy Asthma Proc 2004; 25: 249–252
  • Lee C-W, Matulonis U A, Castells M C. Carboplatin hypersensitivity: a 6-h 12-step protocol effective in 35 desensitivations in patients with gynecological malignancies and mast cell/IgE-mediated reactions. Gynecol Oncol 2004; 95: 370–376
  • Lluch-Bernal M, Cuesta-Herranz J, de las Heras M, et al. Anaphylactic reaction to methotrexate. Allergy 1997; 52: 1150–1151
  • Vega A, Cabanas R, Contreras J, et al. Anaphylaxis to methotrexate: a possible IgE-mediated mechanism. J Allerg Clin Immunol 1994; 94: 268–270
  • Davis K A, Williams P, Walker J C. Successful desensitization to high-dose methotrexate after systemic anaphylaxis. Ann Allergy Asthma Immunol 2003; 90: 87–89

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