Advanced search
Publication Cover
Pediatric Hematology and Oncology Volume 26, 2009 - Issue 7
Submit an article Journal homepage
75
Views
6
CrossRef citations to date
0
Altmetric
Articles

EFFECT OF CHARCOAL HEMOPERFUSION FOR REMOVAL OF PLASMA METHOTREXATE IN A PATIENT WITH ACUTE RENAL FAILURE

Tae Nemoto Division of Pediatrics, Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
, MD,
Chihaya Imai Division of Pediatrics, Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
, MD, PhD,
Utako Kaneko Division of Pediatrics, Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
, MD, PhD,
Takayuki Takachi Division of Pediatrics, Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
, MD,
Haruko Iwabuchi Division of Pediatrics, Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
, MD, PhD,
Atsushi Tanaka Division of Pediatrics, Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
, MD, PhD,
Gen Nakamura Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
, MD, PhD,
Akira Ogose Department of Orthopedic Surgery, Graduate School of Medical and Dental Sciences, Niigata University Hospital, Niigata, Japan
, MD, PhD &
Makoto Uchiyama Division of Pediatrics, Department of Homeostatic Regulation and Development, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
, MD, PhD show all
Pages 520-525 | Received 18 Jun 2008, Accepted 26 Mar 2009, Published online: 08 Oct 2009

REFERENCES

  • Widemann B C, Balis F M, Kempf-Bielack B, et al. High-dose methotrexate-induced nephrotoxicity in patients with osteosarcoma. Cancer. 2004; 100: 2222–2232
  • Rosen G, Caparros B, Huvos A G. Preoperative chemotherapy for osteogenic sarcoma: selection of postoperative adjuvant chemotherapy based on the response of the primary tumor to preoperative chemotherapy. Cancer. 1982; 49: 1221–1230
  • Flombaum C D, Meyers P A. High-dose leucovorin as sole therapy for methotrexate toxicity. J Clin Oncol. 1999; 17: 1589–1594
  • Frappaz D, Bouffett E, Cochat P, et al. Hemoperfusion on charcoal and hemodialysis in acute methotrexate intoxication. Presse Med 1988; 17: 1209–1213
  • Relling M V, Stapleton F B, Ochs J, et al. Removal of methotrexate, leucovorin, and their metabolites by combined hemodialysis and hemoperfusion. Cancer 1988; 62: 884–888
  • Molina R, Fabian C, Cowley B, Jr. Use of charcoal hemoperfusion with sequential hemodialysis to reduce serum methotrexate levels in a patient with acute renal insuffiency. Am J Med 1987; 82: 350–352
  • Ahmad S, Shen F H, Bleyer W A. Methotrexate-induced renal failure and ineffectiveness of peritoneal dialysis. Arch Intern Med 1978; 138: 1146–1147
  • Hande K R, Balow J E, Drake J C, Rosenberg S A, Chabner B A. Methotrexate and hemodialysis. Ann Intern Med 1977; 87: 495–496
  • Bouffet E, Frappaz D, Laville M, et al. Charcoal haemoperfusion and methotrexate toxicity. Lancet 1986; 1(8496)1497.
  • Howell S B, Blair H E, Uren J, et al. Hemodialysis and enzymatic cleavage of methotrexate in man. Eur J Cancer 1978; 14: 787–792
  • Giardino R, Fini M, Giavaresi, et al. Comparison of hemodialysis versus hemoperfusion in the clearance of high-dose methotrexate in pigs. Artif Organs 1995; 19: 362–365
  • Thierry F X, Vernier I, Dueymes J M, et al. Acute renal failure after high-dose methotrexate therapy. Nephron 1989; 51: 416–417
  • Cecyn K Z, Lee J, Oguro T, Petrilli A S, Bordin J O. Use of plasma exchange in methotrexate removal in a patient with osteosarcoma and acute renal insufficiency. Am J Hematol 2003; 72: 209–211
  • Djerassi I, . Controversies in Oncology, , et al. Wiley, New York 1982; 325–352
  • Pinedo H M, Zaharko D S, Bull J M, et al. The reversal of methotrexate cytotoxicity to mouse bone marrow cells by leucovorin and nucleosides. Cancer Res 1976; 36: 4418–4424
  • Widemann B C, Adamson P C. Understanding and managing methotrexate nephrotoxicity. The Oncologist. 2006; 11: 694–703
  • Buchen S, Ngampolo D, Melton R G, et al. Carboxypeptidase G2 rescue in patients with methotrexate intoxication and renal failure. Br J Cancer 2005; 92: 480–487
  • Widemann B C, Hetherington M L, Murphy R F, Balis F M, Adamo P C. Carboxypeptidase-G2 rescue in a patient with high dose methotrexate-induced nephotoxicity. Cancer 1995; 76: 521–526

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.