Treatment challenges and outcomes for pediatric intracranial ependymoma at a single institution in Iran

References

• Pejavar S, Polley MY, Rosenberg-Wohl S, et al. Pediatric intracranial ependymoma: the roles of surgery, radiation and chemotherapy. J Neurooncol. 2012;106(2):367–375. doi:10.1007/s11060-011-0671-9. PMID: 21826561.
   PubMed Web of Science ®Google Scholar
• Lin FY, Chintagumpala M. Advances in management of pediatric ependymomas. Curr Oncol Rep. 2015;17(10):47. doi:10.1007/s11912-015-0470-0. PMID: 26369328.
   PubMed Web of Science ®Google Scholar
• Merchant TE, Li C, Xiong X, et al. Conformal radiotherapy after surgery for paediatric ependymoma: a prospective study. Lancet Oncol. 2009;10(3):258–266. doi:10.1016/S1470-2045(08)70342-5. PMID: 19274783.
   PubMed Web of Science ®Google Scholar
• Garvin JH Jr, Selch MT, Holmes E, et al. Phase II study of pre‐irradiation chemotherapy for childhood intracranial ependymoma. Children's Cancer Group protocol 9942: A report from the Children's Oncology Group. Pediatr Blood Cancer. 2012;59(7):1183–1189. doi:10.1002/pbc.24274. PMID: 22949057.
   PubMed Web of Science ®Google Scholar
• Boström A, Boström J, Hartmann W, et al. Treatment results in patients with intracranial ependymomas. Cent Eur Neurosurg. 2011;72(3):127–132. doi:10.1055/s-0031-1273745. PMID: 21630189.
   PubMedGoogle Scholar
• Chan MH, Boop F, Qaddoumi I. Challenges and opportunities to advance pediatric neuro-oncology care in the developing world. Childs Nerv Syst. 31(8):1227–1237. doi:10.1007/s00381-015-2771-x. PMID: 26040936.
   PubMed Web of Science ®Google Scholar
• Liu AP, Shing MM, Yuen HL, et al. Timing of adjuvant radiotherapy and treatment outcome in childhood ependymoma. Pediatr Blood Cancer. 2014;61(4):606–611. doi:10.1002/pbc.24820. PMID: 24167035.
   PubMed Web of Science ®Google Scholar
• El-Gaidi MA, Eissa EM. Infantile intracranial neoplasms: characteristics and surgical outcomes of a contemporary series of 21 cases in an Egyptian referral center. Pediatr Neurosurg. 46(4):272–282. doi:10.1159/000321540. PMID: 21160236.
   PubMed Web of Science ®Google Scholar
• Mehrvar N, Mehrvar A, Akbari ME, et al. Comprehensive analysis of Iranian reports of pediatric central nervous system tumors. Child's Nervous Syst. 2017;33(9):1481–1490.
   PubMed Web of Science ®Google Scholar
• Samad A, Daneshbod K. Soft tissue ependymoma in the sacrococcygeal region. Iran J Surg. 1980;3:243–247.
   Google Scholar
• Ansari SH, Vosough P, Mo'udi S. Determination of the main epidemiological factors in children with brain tumor admitted to Hazrat Ali Asghar Children Hospital. Razi J Med Sci Iran Univ Med Sci. 2003;10(36):535–539.
   Google Scholar
• Mahzuni P, Moghaddam NA. Histopathological study of primary pediatric brain tumor from 1993 to 2003 in Isfahan. J Res Med Sci. 2006;11(3):203.
   Google Scholar
• Mehrazin M, Yavari P. Morphological pattern and frequency of intracranial tumors in children. Childs Nerv Syst. 2007;23(2):157–162. doi:10.1007/s00381-006-0198-0. PMID: 16953459.
   PubMed Web of Science ®Google Scholar
• Mehrvar A, Faranoush M, Asl AAH, et al. Childhood central nervous system tumors at MAHAK's Pediatric Cancer Treatment and Research Center (MPCTRC), Tehran, Iran. Childs Nerv Syst. 2014;30(3):491–496. doi:10.1007/s00381-013-2256-8. PMID: 23943227.
   PubMed Web of Science ®Google Scholar
• Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, et al. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathologica. 2007;114(2):97–109. doi:10.1007/s00401-007-0243-4. PMID: 17618441.
   PubMed Web of Science ®Google Scholar
• Grill J, Le Deley MC, Gambarelli D, et al. Postoperative chemotherapy without irradiation for ependymoma in children under 5 sources of age: a multicenter trial of the French Society of Pediatric Oncology. J Clin Oncol. 2001;19(5):1288–1296. doi:10.1200/JCO.2001.19.5.1288. PMID: 11230470.
   PubMed Web of Science ®Google Scholar
• Marinoff A, Guo D, Ma C, et al. EPN-14 pediatric ependymoma: multi-institutional experience reveals poor long-term overall survival despite favorable five-source outcomes. Neuro Oncol. 2016;18(suppl 3):iii33. doi:10.1093/neuonc/now070.13.
   Google Scholar
• Massimino M, Miceli R, Giangaspero F, et al. Final results of the second prospective AIEOP protocol for pediatric intracranial ependymoma. Neuro Oncol. 2016;18(10):1451–1460. doi:10.1093/neuonc/now108. PMID: 27194148.
   PubMed Web of Science ®Google Scholar
• Ahmed N, Bhurgri Y, Sadiq S, et al. Pediatric brain tumours at a tertiary care hospital in Karachi. Asian Pac J Cancer Prev. 2007;8(3):399–404. PMID: 18159977.
   PubMedGoogle Scholar
• Korshunov A, Golanov A, Sycheva R, et al. The histologic grade is a main prognostic factor for patients with intracranial ependymomas treated in the microneurosurgical era: an analysis of 258 patients. Cancer. 2004;100(6):1230–1237. doi:10.1002/cncr.20075. PMID: 15022291.
   PubMed Web of Science ®Google Scholar
• Andrade FG, de Aguiar PH, Matushita H, et al. IntracranIal and spinal ependymoma. Arq Neuropsiquiatr. 2009;67(3A):626–632. doi:10.1590/S0004-282X2009000400010. PMID: 19722039.
   PubMed Web of Science ®Google Scholar
• Ezzat S, Kamal M, El-Khateeb N, et al. Pediatric brain tumors in a low/middle income country: does it differ from that in developed world? J Neurooncol. 2016;126(2):371–376. doi:10.1007/s11060-015-1979-7. PMID: 26514358.
   PubMed Web of Science ®Google Scholar
• Houjami M, Sahraoui S, Benchakroun N, et al. Intracranial ependymomas: retrospective study of 16 cases (translation). Cancer/Radiothérapie. 2011;15(2):136–139. doi:10.1016/j.canrad.2010.09.001.
   Google Scholar
• Ho DMT, Hsu CY, Wong TT, et al. A clinicopathologic study of 81 patients with ependymomas and proposal of diagnostic criteria for anaplastic ependymoma. J Neurooncol. 2001;54(1):77–85. doi:10.1023/A:1012590505236. PMID: 11763426.
   PubMed Web of Science ®Google Scholar
• Ostrom QT, Gittleman H, de Blank PM, et al. American Brain Tumor Association adolescent and young adult primary brain and central nervous system tumors diagnosed in the United States in 2008–2012. Neuro Oncol. 2016;18(suppl 1):i1–i50. doi:10.1093/neuonc/nov297. PMID: 26705298.
   PubMedGoogle Scholar
• Burger PC. Atlas of tumor pathology: tumors of the central nervous system. 2000.
   Google Scholar
• Ellison DW, Kocak M, Figarella-Branger D, et al. Histopathological grading of pediatric ependymoma: reproducibility and clinical relevance in European trial cohorts. J Negative Results Biomed. 2011;10(1):7. doi:10.1186/1477-5751-10-7.
   PubMedGoogle Scholar
• Taylor RE. Review of radiotherapy dose and volume for intracranial ependymoma. Pediatr Blood Cancer. 2004;42(5):457–460. doi:10.1002/pbc.10470. PMID: 15049020.
   PubMed Web of Science ®Google Scholar
• Paulino AC, Wen BC. The significance of radiotherapy treatment duration in intracranial ependymoma. Int J Radiat Oncol Biol Phys. 2000;47(3):585–589. doi:10.1016/S0360-3016(99)00535-0. PMID: 10837939.
   PubMed Web of Science ®Google Scholar
• Chemotherapy for Ependymomas in Children: International Society for Pediatric Neurosurgery. Available at: https://www.ispn.guide/tumors-of-the-nervous-system-in-children/chemotherapy-for-tumors-in-the-nervous-system-of-children-homepage/management-with-chemotherapy-of-tumors-in-the-nervous-system-of-children/chemotherapy-for-ependymomas-in-children/.
   Google Scholar
• Merchant TE, Fouladi M. Ependymoma: new therapeutic approaches including radiation and chemotherapy. J Neurooncol. 2005;75(3):287–299. doi:10.1007/s11060-005-6753-9. PMID: 16195801.
   PubMed Web of Science ®Google Scholar
• Wright KD, Gajjar A. New chemotherapy strategies and biological agents in the treatment of childhood ependymoma. Childs Nerv Syst. 2009;25(10):1275–1282. doi:10.1007/s00381-009-0809-7. PMID: 19212772.
   PubMed Web of Science ®Google Scholar
• Pollack IF, Gerszten PC, Martinez AJ, et al. Intracranial ependymomas of childhood: long‐term outcome and prognostic factors. Neurosurgery. 1995;37(4):655–667. doi:10.1227/00006123-199510000-00008. PMID: 8559293.
   PubMed Web of Science ®Google Scholar
• Boop FA. Repeat surgery for residual ependymoma. J Neurosurg Pediatr. 2011;8(3):244. doi:10.3171/2011.5.PEDS11173. PMID: 21882913.
   PubMed Web of Science ®Google Scholar
• Massimino M, Solero CL, Garrè ML, et al. Second-look surgery for ependymoma: the Italian experience. J Neurosurg: Pediatr. 2011;8(3):246–250. PMID: 21882914.
   PubMed Web of Science ®Google Scholar
• Van Poppel M, Klimo Jr P, Dewire M, et al. Resection of infantile brain tumors after neoadjuvant chemotherapy: the St. Jude experience. J Neurosurg: Pediatr. 2011;8(3):251–256. PMID: 21882915.
   PubMed Web of Science ®Google Scholar
• Sanford RA, Merchant TE, Zwienenberg-Lee M, et al. Advances in surgical techniques for resection of childhood cerebellopontine angle ependymomas are key to survival. Child's Nervous Syst. 2009;25(10):1229–1240. doi:10.1007/s00381-009-0886-7.
   PubMed Web of Science ®Google Scholar
• Qaddoumi I, Musharbash A, Elayyan M, et al. Closing the survival gap: Implementation of medulloblastoma protocols in a low‐income country through a twinning program. Int J Cancer. 2008;122(6):1203–1206. doi:10.1002/ijc.23160. PMID: 17985345.
   PubMed Web of Science ®Google Scholar