Advanced search
Publication Cover
Pediatric Hematology and Oncology Volume 36, 2019 - Issue 6
Submit an article Journal homepage
114
Views
1
CrossRef citations to date
0
Altmetric
Brief Report

A case of compound heterozygous hemoglobin Köln/hemoglobin E in an Indian family

Navkirti MittalDepartment of Hematology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India;
,
Akanksha GargDepartment of Hematology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India;
,
Rajesh KashyapDepartment of Hematology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India; Correspondence[email protected]
&
Sarita AgarwalDepartment of Medical Genetics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
Pages 394-398 | Received 28 Feb 2019, Accepted 21 Jul 2019, Published online: 19 Aug 2019

References

  • Warang P, Nair S, Nadkarni A. Hb Koln [β98(FG5) [GTG → ATG, Val → Met]: the first report from India. Hematology. 2014; 19(4):199–201. doi: 10.1179/1607845413Y.0000000116.
  • Horst J, Oehme R, Kohne E. Hemoglobin Köln: Direct analysis of the gene mutation by synthetic DNA probes. Blood. 1986;68(5):1175–1177.
  • Balgir RS. The burden of haemoglobinopathies in India and the challenges ahead. Current Sci. 2000; 79:1536–1547.
  • Carrell RW, Lehmann H, Hutchison HE. Hemoglobin Köln (beta-98 valine-methionine): an unstable protein causing inclusion-body anemia. Nature. 1966; 210(5039):915–916. doi: 10.1038/210915a0.
  • Williamson D. The unstable haemoglobins. Blood Rev. 1993;7(3):146–163.
  • Egan E, Fairbanks VF. Postsplenectomy erythrocytosis in hemoglobin Köln disease. N Engl J Med. 1973;288(18):929–931. doi: 10.1056/NEJM197305032881802.
  • Pscheidt S, Perelma IML, Roberge MB, Rotto MAS, Genovez G, Zunino JN. Köln unstable hemoglobin: case report and literature review. J Bras Med Lab. 2003;39:37–40.
  • Sharma VS, Nobel RW, Ranney HM. Structure-function relation in hemoglobin Köln disease. Br J Hematol 1976;33:279.
  • Szuberski J, Oliveira JL, Hoyer JD. A comprehensive analysis of hemoglobin variants by high- performance liquid chromatography (HPLC). Int J Lab Hematol. 2012; 34(6):594–604. doi: 10.1111/j.1751-553X.2012.01440.x.
  • Galacteros F, Loukopoulos D, Fessas P. Hemoglobin Köln occurring in association with a β0 thalassemia: hematologic and functional consequences. Blood 1989; 74(1):496–500.
  • Olivieri NF, Pakbaz Z, Vinchinsky C. Hb E/beta-thalassemia: a common & clinically diverse disorder. Indian J Med Res. 2011; 134:522–531.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.