Links Between Type I Interferons and the Genetic Basis of Disease in Mouse Lupus

References

• Early, G.S., Zhao, W. and Burns, C.M. (1996) "Anti-CD40 ligand antibody treatment prevents the development of lupus- like nephritis in a subset of New Zealand black x New Zealand white mice. Response correlates with the absence of an anti-antibody response", J. Immunol. 157, 3159–3164
   PubMed Web of Science ®Google Scholar
• Daikh, DJ., Finck, BK., Linsley, P.S., Hollenbaugh, D. and Wofsy, D. (1997) "Long-term inhibition of murine lupus by brief simultaneous blockade of the B7/CD28 and CD40/gp39 costimulation pathways", J. Immunol. 159, 3104–3108
   PubMed Web of Science ®Google Scholar
• Datta, S.K. and Kalled, S.L. (1997) "CD4O—CD40 ligand interaction in autoimmune disease", Arthritis Rheum. 40, 1735–1745
   PubMed Web of Science ®Google Scholar
• Lettesjo, H., Burd, G.P. and Mageed, R.A. (2000) "CD4+ T lymphocytes with constitutive CD40 ligand in preautoimmune (NZB x NZW)F1 lupus-prone mice: phenotype and possible role in autoreactivity", J. Immunol. 165, 4095–4104
   PubMed Web of Science ®Google Scholar
• Higuchi, T., Aiba, Y, Nomura, T., Matsuda, J., Mochida, K., Suzuki, M., et al. (2002) "Cutting edge: ectopic expression of CD40 ligand on B cells induces lupus-like autoimmune disease", J. Immunol. 168, 9–12
   PubMed Web of Science ®Google Scholar
• Wuthrich, R.P., Jevnikar, AM., Takei, F., Glimcher, L.H. and Kelley, V.E. (1990) "Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated in autoimmune murine lupus nephritis", Am. J. Pathol. 136, 441–450
   PubMed Web of Science ®Google Scholar
• Chakrabarti, D., Hultgren, B. and Stewart, T.A. (1996) "1FN-alpha induces autoimmune T-cells through the induction of intracellular adhesion molecule-1 and b7.2", J. Immunol. 157, 522–528
   PubMed Web of Science ®Google Scholar
• Seko, Y, Takahashi, N., Oshima, H., Shimozato, O., Akiba, H., Takeda, K., et al. (2001) "Expression of tumour necrosis factor (TNF) ligand superfamily co- stimulatory molecules CD3OL, CD27L, OX4OL, and 4-1BBL in murine hearts with acute myocarditis caused by Coxsackievirus B3", J. Pathol. 195, 593–603
   PubMed Web of Science ®Google Scholar
• Foell, J., Strahotin, S., O'Neil, SY., McCausland, M.M., Suwyn, C., Haber, M., et al. (2003) "CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F(1) mice", J. Clin. Investig. 111, 1505–1518
   PubMed Web of Science ®Google Scholar
• Padovan, E., Spagnoli, G.C., Ferrantini, M. and Heberer, M. (2002) "1FN-alpha2a induces 1P-10/CXCL10 and 1VIIG/CXCL9 production in monocyte- derived dendritic cells and enhances their capacity to attract and stimulate CD8+ effector T cells", J. Leukoc. Biol. 71, 669–676
   PubMed Web of Science ®Google Scholar
• Dufour, J.H., Dziejman, M., Liu, M.T., Leung, J.H., Lane, T.E. and Luster, A.D. (2002) "1FN-gamma-inducible protein 10 (1P-10; CXCL10)-deficient mice reveal a role for 1P-10 in effector T cell generation and trafficking", J. Immunol. 168, 3195–3204
   PubMed Web of Science ®Google Scholar
• Zhang, Y, Schlossman, S.F., Edwards, R.A., Ou, C.N., Gu, J. and Wu, M.X. (2002) "Impaired apoptosis, extended duration of immune responses, and a lupus- like autoimmune disease in 1EX-1-transgenic mice", Proc. Natl Acad. Sci. USA 99, 878–883
   PubMed Web of Science ®Google Scholar
• Bickerstaff, M.C., Botto, M., Hutchinson, W.L., Herbert, J., Tennent, G.A., Bybee, A., et al. (1999) "Serum amyloid P component controls chromatin degradation and prevents anti-nuclear autoimmunity", Nat. Med. 5, 694–697
   PubMed Web of Science ®Google Scholar
• Cohen, P.L., Caricchio, R., Abraham, V., Camenisch, T.D., Jennette, J.C., Roubey, R.A., et al. (2002) "Delayed apoptotic cell clearance and lupus-like autoimmunity in mice lacking the c-mer membrane tyrosine kinase", J. Exp. Med. 196, 135–140
   PubMed Web of Science ®Google Scholar
• [ Boes, M., Schmidt, T., Linkemann, K., Beaudette, B.C., Marshak-Rothstein, A. and Chen, J. (2000) "Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM", Proc. Natl Acad. Sci. USA 97, 1184–1189
   PubMed Web of Science ®Google Scholar
• Botto, M., Dell'Agnola, C., Bygrave, A.E., Thompson, E.M., Cook, H.T., Petry, F., et al. (1998) "Homozygous Clq deficiency causes glomerulonephritis associated with multiple apoptotic bodies", Nat. Genet. 19, 56–59
   PubMed Web of Science ®Google Scholar
• Paul, E., Pozdnyakova, O.O., Mitchell, E. and Carroll, M.C. (2002) "Anti-DNA autoreactivity in C4-deficient mice", Eur. J. Immunol. 32, 2672–2679
   PubMed Web of Science ®Google Scholar
• Zhang, L., Eddy, A., Teng, Y.T., Fritzler, M., Kluppel, M., Melet, F. and Bernstein, A. (1995) "An immunological renal disease in transgenic mice that overexpress Fli-1, a member of the ets family of transcription factor genes", MoL Cell Biol. 15, 6961–6970
   PubMed Web of Science ®Google Scholar
• Khare, S.D., Sarosi, I., Xia, X.Z., McCabe, S., Miner, K., Solovyev, I., et al. (2000) "Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice", Proc. Natl Acad. Sci. USA 97, 3370–3375
   PubMed Web of Science ®Google Scholar
• Sato, S., Hasegawa, M., Fujimoto, M., Tedder, T.F. and Takehara, K. (2000) "Quantitative genetic variation in CD19 expression correlates with autoimmunity", J. Immunol. 165, 6635–6643
   PubMed Web of Science ®Google Scholar
• Wang, J., Lo, IC., Foster, A., Yu, P., Chen, H.M., Wang, Y, et al (2001) "The regulation of T cell homeostasis and autoimmunity by T cell-derived LIGHT", J. Clin. Investig. 108, 1771–1780
   PubMed Web of Science ®Google Scholar
• Shultz, L.D. and Green, M.C. (1976) "Motheaten, an immuno-deficient mutant of the mouse. II. Depressed immune competence and elevated serum immunoglobulins", J. Immunol. 116, 936— 943
   Web of Science ®Google Scholar
• O'Keefe, T.L., Williams, G.T., Davies, S.L. and Neuberger, M.S. (1996) "Hyperresponsive B cells in CD22-deficient mice", Science 274, 798–801
   PubMed Web of Science ®Google Scholar
• Hibbs, ML., Tarlinton, D.M., Armes, J., Grail, D., Hodgson, G., Maglitto, R., et al. (1995) "Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease", Cell 83, 301–311
   PubMed Web of Science ®Google Scholar
• Seshasayee, D., Valdez, P., Yan, M., Dixit, V.M., Tumas, D. and Grewal, IS. (2003) "Loss of TACI causes fatal lymphoprolifera-don and autoimmunity, establishing TACI as an inhibitory BLyS receptor", Immunity 18, 279–288
   PubMed Web of Science ®Google Scholar
• Cazac, B.B. and Roes, J. (2000) "TGF-beta receptor controls B cell responsiveness and induction of IgA in vivo", Immunity 13, 443–451
   PubMed Web of Science ®Google Scholar
• Majeti, R., Xu, Z., Parslow, T.G., Olson, J.L., Daikh, DJ., Killeen, N. and Weiss, A. (2000) "An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity", Cell 103, 1059–1070
   PubMed Web of Science ®Google Scholar
• Gorelik, L. and Flavell, R.A. (2000) "Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease", Immunity 12, 171–181
   PubMed Web of Science ®Google Scholar
• Sun, H., Lu, B., Li, R.Q., Flavell, R.A. and Taneja, R. (2001) "Defective T cell activation and autoimmune disorder in Stral 3-deficient mice", Nat. Immunol. 2, 1040–1047
   PubMed Web of Science ®Google Scholar
• Ruger, B.M., Erb, K.J., He, Y., Lane, J.M., Davis, P.F. and Hasan, Q. (2000) "Interleukin-4 transgenic mice develop glomerulosclerosis independent of immunoglobulin deposition", Eur. J. Immunol. 30, 2698–2703
   PubMed Web of Science ®Google Scholar
• Seery, J.P., Carroll, J.M., Cattell, V. and Watt, F.M. (1997) "Antinuclear autoantibodies and lupus nephritis in transgenic mice expressing interferon gamma in the epidermis", J. Exp. Med. 186, 1451–1459
   PubMed Web of Science ®Google Scholar
• Dang, H., Geiser, AG., Letterio, J.J., Nakabayashi, T., Kong, L., Fernandes, G. and Talal, N. (1995) "SLE-like autoantibodies and Sjogren's syndrome-like lymphoproliferation in TGF-beta knock-out mice", J. Immunol. 155, 3205–3212
   PubMed Web of Science ®Google Scholar
• Ym, Z., Bahtiyar, G., Zhang, N., Liu, L., Zhu, P., Robert, M.E., et al. (2002) "IL-10 regulates murine lupus", J. Immunol. 169, 2148–2155
   PubMed Web of Science ®Google Scholar
• Dean, G.S., Tyrrell-Price, J., Crawley, E. and Isenberg, D.A. (2000) "Cytokines and systemic lupus erythematosus", Ann. Rheum. Dis. 59, 243
   PubMed Web of Science ®Google Scholar
• Lawson, B.R., Prud'homme, G.J., Chang, Y., Gardner, HA., Kuan, J., Kono, D.H. and Theofilopoulos, AN. (2000) "Treatment of murine lupus with cDNA encoding 1FN-gammaR/Fc", J. Clin. Investig. 106, 207–215
   PubMed Web of Science ®Google Scholar
• McMurray, R.W., Hoffman, R.W., Nelson, W. and Walker, S.E. (1997) "Cytokine mRNA expression in the B/W mouse model of systemic lupus erythematosus—analyses of strain, gender, and age effects", Clin. Immunol. Immunopathol. 84, 260–268
   PubMedGoogle Scholar
• Jacob, C.O., Van Der Meide, P.H. and McDevitt, H.O. (1987) "In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon", J. Exp. Med. 166, 798–803
   PubMed Web of Science ®Google Scholar
• Haas, C., Ryffel, B. and Lehir, M. (1997) "Ifn-gamma is essential for the development of autoimmune glomerulonephritis in mr1.1pr mice", J. Immunol. 158, 5484–5491
   PubMed Web of Science ®Google Scholar
• Peng, S.L., Moslehi, J. and Craft, J. (1997) "Roles of interferon-gamma and interleukin-4 in murine lupus", J. Clin. Investig. 99, 1936–1946
   PubMed Web of Science ®Google Scholar
• Haas, C., Ryffel, B. and Le Hir, M. (1998) "IFN-gamma receptor deletion prevents autoantibody production and glomerulonephritis in lupus-prone (NZB x NZW)F1 mice", J. Immunol. 160, 3713–3718
   PubMed Web of Science ®Google Scholar
• Schwarting, A., Wada, T., Kinoshita, K., Tesch, G. and Kelley, V.R. (1998) "IFN-gamma receptor signaling is essential for the initiation, acceleration, and destruction of autoimmune kidney disease in MRL- Fas(lpr) mice", J. Immunol. 161, 494–503
   PubMed Web of Science ®Google Scholar
• Taniguchi, T. and Takaoka, A. (2001) "A weak signal for strong responses: interferon-alpha/beta revisited", Nat. Rev. Mol. Cell Biol. 2, 378–386
   PubMed Web of Science ®Google Scholar
• Domachowske, LB., Bonville, CA., Mortelliti, A.J., Colella, C.B., Kim, U. and Rosenberg, RE (2000) "Respiratory syncytial virus infection induces expression of the anti- apoptosis gene 1EX-1L in human respiratory epithelial cells", J. Infect. Dis. 181, 824–830
   PubMed Web of Science ®Google Scholar