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Original Article

Monozygotic twins discordant for epilepsy differ in the levels of potentially pathogenic autoantibodies and cytokines

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Pages 139-150 | Received 24 Aug 2004, Accepted 14 Feb 2005, Published online: 07 Jul 2009

References

  • Ganor Y, Goldberg-Stern H, Amrom D, Lerman-Sagie T, Teichberg VI, Pelled D, Futerman AH, Ben-Zeev B, Freilinger M, Verheulpen D, Van Bogaert P, Levite M. Autoimmune epilepsy: Some epilepsy patients harbor autoantibodies to glutamate receptors and dsDNA on both sides of the blood-brain barrier, which may kill neurons and decrease in brain fluids after Hemispherotomy. C lin Dev Immunol 2004;11:241–252.
  • Ganor Y, Goldberg-Stern H, Lerman-Sagie T, Teichberg VI, Levite M. Autoimmune epilepsy: Distinct subpopulations of epilepsy patients harbor serum autoantibodies to either glutamate/AMPA receptor G1uR3, glutamate/NMDA receptor subunit NR2A or double-stranded DNA (Revised) 2005.
  • Mantegazza R, Bernasconi P, Baggi F, Spreafico R, Ragona F, Antozzi C, Bernardi G, Granata T. Antibodies against G1uR3 peptides are not specific for Rasmussen's encephalitis but are also present in epilepsy patients with severe, early onset disease and intractable seizures. J Neuroimmunol 2002;131:179–185.
  • Rogers SW, Andrews PI, Gahring LC, Whisenand T, Cauley K, Crain B, Hughes TE, Heinemann SF, McNamara JO. Autoantibodies to glutamate receptor G1uR3 in Rasmussen's encephalitis. Science 1994;265: 648–651.
  • Wiendl H, Bien CG, Bernasconi P, Fleckenstein B, Elger CE, Dichgans J, Mantegazza R, Melms A. G1uR3 antibodies: Prevalence in focal epilepsy but no specificity for Rasmussen's encephalitis. Neurology 2001;57:1511–1514.
  • Koustova E, Sei Y, Fossom L, Wei ML, Usherwood PN, Keele NB, Rogawski MA, Basile AS. LP-BM5 virus-infected mice produce activating autoantibodies to the AMPA receptor. J Chin Investig 2001;107:737–744.
  • Levite M, Fleidervish IA, Schwarz A, Pelled D, Futerman AH. Autoantibodies to the glutamate receptor kill neurons via activation of the receptor ion channel. J Autoimmun 1999;13:61–72.
  • He XP, Patel M, Whitney KD, Janumpalli S, Termer A, McNamara JO. Glutamate receptor G1uR3 antibodies and death of cortical cells. Neuron 1998;20:153–163.
  • Whitney KD, Andrews PI, McNamara JO. Immunoglobulin G and complement immunoreactivity in the cerebral cortex of patients with Rasmussen's encephalitis. Neurology 1999;53:699–708.
  • Whitney KD, McNamara JO. G1uR3 autoantibodies destroy neural cells in a complement-dependent manner modulated

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