HLA-DQB1* polymorphism and associations with dilated cardiomyopathy, inflammatory dilated cardiomyopathy and myocarditis^†

References

• Richardson P, McKenna W, Bristow M, Maisch B, Mautner B, O'Connell J, Olsen E, Thiene G, Goodwin J, Gyarfas I, Martin I, Nordet P. Report of the 1995 World Health Organisation/International Society and Federation of Cardiology task force on the definition and classification of cardiomyopathies. Circulation 1996; 93: 841–842
   PubMed Web of Science ®Google Scholar
• Cohn JN, Bristow MR, Chien KR, Colucci WS, Frazier OH, Leinwand LA, Lorell BH, Moss AJ, Sonnenblick EH, Walsh RA, Mockrin SC, Reinlib L. Report of the national heart, lung, and blood institute special emphasis panel on heart failure research. Circulation 1997; 95: 766–770
   PubMed Web of Science ®Google Scholar
• Felker GM, Thompson RE, Hare JM, Hruban RH, Clemetson DE, Howard DL, Baughman KL, Kasper EK. Underlying causes and long-term survival in patients with initially unexplained cardiomyopathy. N Engl J Med 2000; 342: 1077–1084
   PubMed Web of Science ®Google Scholar
• Mestroni L, Rocco C, Gregori D, Sinagra G, Di Lenarda A, Miocic S, Vatta M, Pinamonti B, Muntoni F, Caforio AL, McKenna WJ, Falaschi A, Giacca M, Camerini F. Familial dilated cardiomyopathy: Evidence for genetic and phenotypic heterogeneity. Heart muscle disease study group. J Am Coll Cardiol 1999; 34: 181–190
   PubMed Web of Science ®Google Scholar
• Towbin JA, Bowles NE. Genetic abnormalities responsible for dilated cardiomyopathy. Curr Cardiol Rep 2000; 2: 475–480
   PubMedGoogle Scholar
• Bowles NE, Ni J, Kearney DL, Pauschinger M, Schultheiss HP, McCarthy R, Hare J, Bricker JT, Bowles KR, Towbin JA. Detection of viruses in myocardial tissues by polymerase chain reaction. Evidence of adenovirus as a common cause of myocarditis in children and adults. J Am Coll Cardiol 2003; 42: 466–472
   PubMed Web of Science ®Google Scholar
• Rose NR, Herskowitz A, Neumann DA, Neu N. Autoimmune myocarditis: A paradigm of post-infectious autoimmune disease. Immunol Today 1988; 9: 117–120
   PubMedGoogle Scholar
• Maisch B, Ristic AD, Hufnagel G, Pankuweit S. Pathophysiology of viral myocarditis. The role of humoral response. Cardiovasc Pathol 2002; 11: 112–122
   PubMedGoogle Scholar
• Nakamura H, Yamamura T, Umemoto S, Fukuta S, Shioi T, Matsumori A, Sasayama S, Matsuzaki M. Autoimmune response in chronic ongoing myocarditis demonstrated by heterotopic cardiac transplantation in mice. Circulation 1996; 94: 3348–3354
   PubMedGoogle Scholar
• Liu PP, Mason JW. Advances in the understanding of myocarditis. Circulation 2001; 104: 1076–1082
   PubMed Web of Science ®Google Scholar
• Eriksson U, Ricci R, Hunziker L, Kurrer MO, Oudit GY, Watts TH, Sonderegger I, Bachmeier K, Kopf M, Penninger JM. Dendritic cell-induced autoimmune heart failure requires cooperation between adaptive and innate immunity. Nat Med 2003; 9: 1448–1490
   Google Scholar
• McKenna CJ, Codd MB, McCann HA, Sugrue DD. Idiopathic dilated cardiomyopathy: Familial prevalence and HLA distribution. Heart 1997; 77: 549–552
   PubMedGoogle Scholar
• Pankuweit S, Portig I, Lottspeich F, Maisch B. Autoantibodies in sera of patients with myocarditis: Characterisation of the corresponding proteins by isoelectric focusing and N-terminal sequence analysis. J Mol Cell Cardiol 1997; 29: 77–84
   PubMedGoogle Scholar
• Portig I, Pankuweit S, Maisch B. Antibodies against stress proteins in sera of patients with dilated cardiomyopathy. J Mol Cell Cardiol 1997; 29: 2245–2251
   PubMed Web of Science ®Google Scholar
• Schultheiss HP, Schulze K, Kuhl U, Ulrich G, Klingenberg M. The ADP/ATP carrier as a mitochondrial auto-antigen—facts and perspectives. Ann NY Acad Sci 1986; 488: 44–64
   PubMedGoogle Scholar
• Caforio AL, Mahon NJ, Tona F, McKenna WJ. Circulating autoantibodies in dilated cardiomyopathy and myocarditis: Pathogenetic and clinical significance. Eur J Heart Fail 2002; 4: 411–417
   PubMed Web of Science ®Google Scholar
• Limas CJ, Iakovis P, Anyfantakis A, Kroupis C, Cokkinos DV. Familial clustering of autoimmune disease in patients with dilated cardiomyopathy. Am J Cardiol 2004; 93: 1189–1191
   PubMed Web of Science ®Google Scholar
• Taylor JA, Havari E, McInerney MF, Wucherpfennig KW, Lipes MA. A spontanous model for autoimmune myocarditis using the human MHC molecule HLA-DQ8. J Immunol 2004; 172: 2651–2658
   PubMed Web of Science ®Google Scholar
• Liu J, Purdy LE, Rabinovitch S, Jevnikar AM, Elliott JF. Major DQ8-restricted T-cell epitopes for human GAD65 mapped using human CD4, DQA1*0301, DQB1*0302 transgenic IA(null) NOD mice. Diabetes 1999; 48: 469–477
   PubMedGoogle Scholar
• Carlquist JF, Menlove RL, Murray MB, O'Connell JB, Anderson JL. HLA class II (DR and DQ) antigen associations in idiopathic dilated cardiomyopathy. Circulation 1991; 83: 515–522
   PubMedGoogle Scholar
• Aretz HT. Myocarditis: The Dallas criteria. Hum Pathol 1987; 18: 619–662
   PubMed Web of Science ®Google Scholar
• Portig I, Wilke A, Freyland M, Wolf M, Richter A, Ruppert V, Pankuweit S, Maisch B. Familial inflammatory dilated cardiomyopathy. Eur J Heart Fail 2006; 8: 816–825
   PubMed Web of Science ®Google Scholar
• Mueller CR, Goldmann SF, Wegener S. Population studies. German normal. HLA 1998, DW Gjertson, PI Terasaki. American Society for Histocompatibility and Immunogenetics, Lenexa, Kansas 1998; 154–157
   Google Scholar
• Pankuweit S, Portig I, Eckhardt H, Crombach M, Hufnagel G, Maisch B. Prevalence of viral genome in endomyocardial biopsies from patients with inflammatory heart muscle disease. Herz 2000; 25: 221–226
   PubMedGoogle Scholar
• Olerup O, Zetterquist H. HLA-DR typing by PCR amplification with SSP-PCR in two hours: An alternative to serological DR typing in clinical practice including donor-recipient match in cadaveric transplantation. Tissue Antigens 1992; 39: 225–235
   PubMed Web of Science ®Google Scholar
• Lozano MD, Rubocki RJ, Wilson JE, McManus BM, Wisecarver JL. Human leukocyte antigen class II associations in patients with idiopathic dilated cardiomyopathy. Myocarditis treatment trial investigators. J Card Fail 1997; 3: 97–103
   PubMedGoogle Scholar
• Nishi H, Koga Y, Koyanage T, Harada H, Imaizumi T, Tosjima H, Sazuki T, Kimura A. DNA typing of HLA class II genes in Japanese patients with dilated cardiomyopathy. J Mol Cell Cardiol 1995; 27: 2385–2392
   PubMedGoogle Scholar
• Liu W, Li WM, Sun NL. HLA-DQA1, -DQB1 polymorphism and genetic susceptibility to idiopathic dilated cardiomyopathy in Hans of northern China. Ann Hum Genet 2005; 69: 382–388
   PubMed Web of Science ®Google Scholar
• Limas CJ, Limas C, Goldenberg IF, Blair R. Possible involvement of the HLA-DQB1 gene in susceptibility and resistance to human dilated cardiomyopathy. Am Heart J 1995; 129: 1141–1144
   PubMedGoogle Scholar
• Ghodke Y, Joshi K, Chopra A, Patwardhan B. HLA and disease. Eur J Epidemiol 2005; 20: 475–488
   PubMed Web of Science ®Google Scholar
• Hauck AJ, Kearney DL, Edwards WD. Evaluation of postmortem endomyocardial biopsy specimens from 38 patients with lymphocytic myocarditis: Implications for role of sampling error. Mayo Clin Proc 1989; 64: 1235–1245
   PubMed Web of Science ®Google Scholar
• Arif S, Underhill JA, Donaldson P, Conway GS, Peakman M. Human leukocyte antigen-DQB1* genotypes encoding aspartate at position 57 are associated with 3beta-hydroxysteroid dehydrogenase autoimmunity in premature ovarian failure. J Clin Endocrinol Metab 1999; 84: 1056–1060
   PubMedGoogle Scholar
• Yunis JJ, Mobini N, Yunis EJ, Alper CA, Deulofeut R, Rodriguez A, Foster CS, Marcus-Bagley D, Good RA, Ahmed AR. Common major histocompatibility complex class II markers in clinical variants of cicatricial pemphigoid. Proc Natl Acad Sci USA 1994; 91: 7747–7751
   PubMedGoogle Scholar
• Delgado J, Turbay D, Yunis EJ, Yunis JJ, Morton ED, Bhol K, Norman R, Alper CA, Good RA, Ahmed R. A common major histocompatibility complex class II allele HLA-DQB1* 0301 is present in clinical variants of pemphigoid. Proc Natl Acad Sci USA 1996; 93: 8569–8571
   PubMedGoogle Scholar
• Thursz M, Yallop R, Goldin R, Trepo C, Thomas HC. Influence of MHC class II genotype on outcome of infection with hepatitis C virus. The HENCORE group. Hepatitis C European Network for Cooperative Research. Lancet 1999; 354: 2119–2124
   PubMed Web of Science ®Google Scholar
• Voorter CE, Drent M, van den Berg-Loonen EM. Severe pulmonary sarcoidosis is strongly associated with the haplotype HLA-DQB1*0602-DRB1*150101. Hum Immunol 2005; 66: 826–835
   PubMedGoogle Scholar
• Fernandez O, Fernandez V, Alonso A, Caballero A, Luque G, Bravo M, Leon A, Mayorga C, Leyva L, de Ramon E. DQB1*0602 allele shows a strong association with multiple sclerosis in patients in Malaga. Spain J Neurol 2004; 251: 440–444
   PubMedGoogle Scholar
• Matsuki K, Grumet FC, Lin X, Gelb M, Guilleminault C, Dement WC, Mignot E. DQ (rather than DR) gene marks susceptibility to narcolepsy. Lancet 1992; 339: 1052
   PubMedGoogle Scholar
• Kotb M, Norrby-Teglund A, McGeer A, El-Sherbini H, Dorak MT, Khurshid A, Green K, Peeples J, Wade J, Thomson G, Schwartz B, Low DE. An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infections. Nat Med 2002; 8: 1398–1404
   PubMed Web of Science ®Google Scholar
• Todd JA, Bell JI, McDevitt HO. HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 1987; 329: 599–604
   PubMed Web of Science ®Google Scholar
• Smyth CM, McKiernan SM, Hagan R, Pilkington R, O'Regan M, Lawlor E, Kelleher D. Chronic hepatitis C infection and sicca syndrome: A clear association with HLA DQB1*02. Eur J Gastroenterol Hepatol 2007; 19: 493–498
   PubMed Web of Science ®Google Scholar
• Sumnik Z, Cinek O, Tratanic N, Kordonouri O, Kulich M, Roszai B, Arato A, Lebl J, Soltesz G, Danne T, Battelino T, Schober E. Risk of celiac disease in children with type 1 diabetes is modified by positivity for HLA-DQB1*02–DQA1*05 and TNF -308A. Diabetes Care 2006; 29: 858–863
   PubMed Web of Science ®Google Scholar
• Craig ME, Howard NJ, Silink M, Rawlinson WD. Reduced frequency of HLA DRB1*03–DQB1*02 in children with type 1 diabetes associated with enterovirus RNA. J Infect Dis 2003; 187: 1562–1570
   PubMedGoogle Scholar
• Martin AM, Nolan D, Gaudieri S, Almeida CA, Nolan R, James I, Carvalho F, Phillips E, Christiansen FT, Purcell AW, McCluskey J, Mallal S. Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proc Natl Acad Sci USA 2004; 101: 4180–4185
   PubMed Web of Science ®Google Scholar
• Jones EY, Fugger L, Strominger JL, Siebold C. MHC class II proteins and disease: A structural perspective. Nat Rev Immunol 2006; 6: 271–282
   PubMed Web of Science ®Google Scholar
• Smith SC, Allen PM. Expression of myosin-class II major histocompatibility complexes in the normal myocardium occurs before induction of autoimmune myocarditis. Proc Natl Acad Sci USA 1992; 89: 9131–9135
   PubMedGoogle Scholar
• Nadal-Ginard B, Kajstura J, Anversa P, Leri A. A matter of life and death: Cardiac myocyte apoptosis and regeneration. J Clin Invest 2003; 111: 1457–1459
   PubMed Web of Science ®Google Scholar
• Dorffel WV, Wallukat G, Dorffel Y, Felix SB, Baumann G. Immunoadsorption in idiopathic dilated cardiomyopathy, a 3-year follow-up. Int J Cardiol 2004; 97: 529–534
   PubMedGoogle Scholar
• Vally M, Seenu S, Pillarisetti S. Emerging peptide therapeutics for inflammatory diseases. Curr Pharm Biotechnol 2006; 7: 241–246
   PubMedGoogle Scholar