Detection by flow cytometry of anti-neutrophil cytoplasmic antibodies in a novel approach based on neutrophil extracellular traps

References

• Davies DJ, Moran JE, Niall JF, et al. Segmental necrotising glomerulonephritis with antineutrophil antibody: possible arbovirus aetiology? Br Med J (Clin Res Ed.) 1982;285:606.
   PubMed Web of Science ®Google Scholar
• Savige J, Dimech W, Fritzler M, et al. Addendum to the international consensus statement on testing and reporting of antineutrophil cytoplasmic antibodies. Am J Clin Pathol. 2003;120:312–318.
   PubMed Web of Science ®Google Scholar
• Jennette JC, Falk RJ, Bacon PA, et al. 2012 revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides. Arthritis Rheum. 2013;65:1–11.
   PubMed Web of Science ®Google Scholar
• Yates M, Watts R. ANCA-associated vasculitis. Clin Med. 2017;17:60–64.
   PubMed Web of Science ®Google Scholar
• Lionaki S, Blyth ER, Hogan SL, et al. Classification of antineutrophil cytoplasmic autoantibody vasculitides: the role of antineutrophil cytoplasmic autoantibody specificity for myeloperoxidase or proteinase 3 in disease recognition and prognosis. Arthritis Rheum. 2012;64:3452–3462.
   PubMed Web of Science ®Google Scholar
• Ara J, Mirapeix E, Rodriguez R, et al. Relationship between ANCA and disease activity in small vessel vasculitis patients with anti-MPO ANCA. Nephrol Dial Transplant. 1999;14:1667–1672.
   PubMed Web of Science ®Google Scholar
• Savige J, Gillis D, Benson E, et al. International consensus statement on testing and reporting of antineutrophil cytoplasmic antibodies (ANCA). Am J Clin Pathol. 1999;111:507–513.
   PubMed Web of Science ®Google Scholar
• Kallenberg CGM. Key advances in the clinical approach to ANCA-associated vasculitis. Nat Rev Rheumatol. 2014;10:484–493.
   PubMed Web of Science ®Google Scholar
• jona2. Antineutrophil cytoplasmic antibodies. In: Rovenský J, Payer J, editors. Dictionary of Rheumatology. Vienna: Springer Vienna; 2009. p. 14.
   Google Scholar
• Csernok E, Moosig F. Current and emerging techniques for ANCA detection in vasculitis. Nat Rev Rheumatol. 2014;10:494–501.
   PubMed Web of Science ®Google Scholar
• Gross WL, Csernok E, Flesch BK. ‘Classic’ anti-neutrophil cytoplasmic autoantibodies (cANCA), ‘Wegener’s autoantigen’ and their immunopathogenic role in Wegener’s granulomatosis. J Autoimmun. 1993;6:171–184.
   PubMed Web of Science ®Google Scholar
• Saxon A, Shanahan F, Landers C, et al. A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease. J Allergy Clin Immunol. 1990;86:202–210.
   PubMed Web of Science ®Google Scholar
• Bossuyt X. Serologic markers in inflammatory bowel disease. Clin Chem. 2006;52:171–181.
   PubMed Web of Science ®Google Scholar
• Roozendaal, Kallenberg. Are anti-neutrophil cytoplasmic antibodies (ANCA) clinically useful in inflammatory bowel disease (IBD)? Clin Exp Immunol. 1999;116:206–213.
   PubMed Web of Science ®Google Scholar
• Teegen B, Niemann S, Probst C, et al. DNA-bound lactoferrin is the major target for antineutrophil perinuclear cytoplasmic antibodies in ulcerative colitis. Ann N Y Acad Sci. 2009;1173:161–165.
   PubMed Web of Science ®Google Scholar
• Tesija Kuna A. Serological markers of inflammatory bowel disease. Biochem Med. 2013;23:28–42.
   Web of Science ®Google Scholar
• Zhou G, Yang S, Yang W, et al. ASCA, ANCA, ALCA and many more: are they useful in the diagnosis of inflammatory bowel disease? Dig Dis. 2016;34:90–97.
   PubMed Web of Science ®Google Scholar
• Mokhtarifar A, Azita G, Sadrneshin M, et al. Diagnostic value of ASCA and atypical p-ANCA in differential diagnosis of inflammatory bowel disease. Middle East J Dig Dis. 2013;5:93–97.
   PubMedGoogle Scholar
• Mallolas J. Antineutrophil antibodies associated with ulcerative colitis interact with the antigen(s) during the process of apoptosis. Gut. 2000;47:74–78.
   PubMed Web of Science ®Google Scholar
• Gilligan HM, Bredy B, Brady HR, et al. Antineutrophil cytoplasmic autoantibodies interact with primary granule constituents on the surface of apoptotic neutrophils in the absence of neutrophil priming. J Exp Med. 1996;184:2231–2241.
   PubMed Web of Science ®Google Scholar
• Yang JJ, Tuttle RH, Hogan SL, et al. Target antigens for anti-neutrophil cytoplasmic autoantibodies (ANCA) are on the surface of primed and apoptotic but not unstimulated neutrophils. Clin Exp Immunol. 2000;121:165–172.
   PubMed Web of Science ®Google Scholar
• Brinkmann V, Reichard U, Goosmann C, et al. Neutrophil extracellular traps kill bacteria. Science. 2004;303:1532–1535.
   PubMed Web of Science ®Google Scholar
• Fuchs TA, Abed U, Goosmann C, et al. Novel cell death program leads to neutrophil extracellular traps. J Cell Biol. 2007;176:231–241.
   PubMed Web of Science ®Google Scholar
• Brinkmann V, Zychlinsky A. Neutrophil extracellular traps: is immunity the second function of chromatin? J Cell Biol. 2012;198:773–783.
   PubMed Web of Science ®Google Scholar
• Leppkes M, Maueroder C, Hirth S, et al. Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis. Nat Commun. 2016;7:10973.
   PubMed Web of Science ®Google Scholar
• Maueroder C, Aparna M, Paulus S, et al. Menage-a-Trois: The Ratio of Bicarbonate to CO2 and the pH Regulate the Capacity of Neutrophils to Form NETs. Front Immunol. 2016;7:583.
   PubMed Web of Science ®Google Scholar
• Vidrich A, Lee J, James E, et al. Segregation of pANCA antigenic recognition by DNase treatment of neutrophils. ulcerative colitis, type 1 autoimmune hepatitis, and primary sclerosing cholangitis. J Clin Immunol. 1995;15:293–299.
   PubMed Web of Science ®Google Scholar
• Hahn J, Knopf J, Maueroder C, et al. Neutrophils and neutrophil extracellular traps orchestrate initiation and resolution of inflammation. Clin Exp Rheumatol. 2016;34:6–8.
   PubMed Web of Science ®Google Scholar
• Mitsios A, Athanasios A, Arelaki S, et al. NETopathies? Unraveling the dark side of old diseases through neutrophils. Front Immunol. 2016;7:678.
   PubMed Web of Science ®Google Scholar
• Kessenbrock K, Krumbholz M, Schonermarck U, et al. Netting neutrophils in autoimmune small-vessel vasculitis. Nat Med. 2009;15:623–625.
   PubMed Web of Science ®Google Scholar
• Soderberg D, Segelmark M. Neutrophil extracellular traps in ANCA-associated vasculitis. Front Immunol. 2016;7:256.
   PubMed Web of Science ®Google Scholar
• Kyriakidi KS, Tsianos VE, Karvounis E, et al. Neutrophil anti-neutrophil cytoplasmic autoantibody proteins: bactericidal increasing protein, lactoferrin, cathepsin, and elastase as serological markers of inflammatory bowel and other diseases. Ann Gastroenterol. 2016;29:258–267.
   PubMed Web of Science ®Google Scholar
• Tsiveriotis K, Tsirogianni A, Pipi E, et al. Antineutrophil cytoplasmic antibodies testing in a large cohort of unselected greek patients. Autoimmune Diseases. 2011;2011:1.
   Google Scholar
• Panda R, Thorsten K, Hopf L, et al. Neutrophil extracellular traps contain selected antigens of anti-neutrophil cytoplasmic antibodies. Front Immunol. 2017;8:439.
   PubMed Web of Science ®Google Scholar
• Nakazawa D, Shida H, Tomaru U, et al. Enhanced formation and disordered regulation of NETs in myeloperoxidase-ANCA-associated microscopic polyangiitis. J Am Soc Nephrol. 2014;25:990–997.
   PubMed Web of Science ®Google Scholar
• Kolaczkowska E, Jenne CN, Surewaard BGJ, et al. Molecular mechanisms of NET formation and degradation revealed by intravital imaging in the liver vasculature. Nat Commun. 2015;6:6673.
   PubMed Web of Science ®Google Scholar