Advanced search
Publication Cover
Autoimmunity Volume 54, 2021 - Issue 7
Submit an article Journal homepage
119
Views
7
CrossRef citations to date
0
Altmetric
Original Articles

Circular RNA circZNF652 is overexpressed in osteoarthritis and positively regulates LPS-induced apoptosis of chondrocytes by upregulating PTEN

Xuefeng Yuana Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei Province, P. R. China
,
Yingchi Zhanga Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei Province, P. R. China
,
Cong Caia Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei Province, P. R. China
,
Chaoxu Liub Department of Orthopaedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei Province, P. R. China
,
Jie Xiea Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei Province, P. R. China
&
Chengla Yia Department of Traumatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan City, Hubei Province, P. R. ChinaCorrespondence[email protected]
Pages 415-421 | Received 03 Nov 2020, Accepted 01 Jul 2021, Published online: 15 Jul 2021

References

  • Glyn-Jones S, Palmer AJR, Agricola R, et al. Osteoarthritis. Lancet. 2015;386(9991):376–387.
  • Vina ER, Kwoh CK. Epidemiology of osteoarthritis: literature update. Curr Opin Rheumatol. 2018;30(2):160–167.
  • Eaton CB, Roberts M, Driban JB, et al. Multiple joint osteoarthritis in the osteoarthritis initiative. Osteoarthr Cartil. 2019;27:S100.
  • Gu YT, Chen J, Meng ZL, et al. Research progress on osteoarthritis treatment mechanisms. Biomed Pharmacother. 2017;93:1246–1252.
  • Banks C, Hughes K, Simpkins C, et al. Osteoarthritis in older adults: nonsteroidal anti-inflammatory drugs versus opioids. Sr Care Pharm. 2019;34(10):674–677.
  • Bahl JS, Nelson MJ, Taylor M, et al. Biomechanical changes and recovery of gait function after total hip arthroplasty for osteoarthritis: a systematic review and meta-analysis. Osteoarthr Cartil. 2018;26(7):847–863.
  • Saito T, Tanaka S. Molecular mechanisms underlying osteoarthritis development: Notch and NF-κB. Arthritis Res Ther. 2017;19(1):94.
  • Galasso O, Panza S, Santoro M, et al. PTEN elevation, autophagy and metabolic reprogramming may be induced in human chondrocytes during steroids or nutrient depletion and osteoarthritis. J Biol Regul Homeost Agents. 2015;29(Suppl 4):1–S14.
  • Roman-Blas JA, Jimenez SA. NF-kappaB as a potential therapeutic target in osteoarthritis and rheumatoid arthritis. Osteoarthr Cartil. 2006;14(9):839–848.
  • Mobasheri A. The future of osteoarthritis therapeutics: targeted pharmacological therapy. Curr Rheumatol Rep. 2013;15(10):364.
  • Qu S, Yang X, Li X, et al. Circular RNA: a new star of noncoding RNAs. Cancer Lett. 2015;365(2):141–148.
  • Yu CX, Sun S. An emerging role for circular RNAs in osteoarthritis. Yonsei Med J. 2018;59(3):349–355.
  • Xiao K, Xia Z, Feng B, et al. Circular RNA expression profile of knee condyle in osteoarthritis by illumina HiSeq platform. J Cell Biochem. 2019;120(10):17500–17511.
  • Liao JM, Zhou X, Zhang Y, et al. MiR-1246: a new link of the p53 family with cancer and Down syndrome. Cell Cycle. 2012;11(14):2624–2630.
  • Brestoff JR, Artis D. Commensal bacteria at the interface of host metabolism and the immune system. Nat Immunol. 2013;14(7):676–684.
  • Redlich K, Smolen JS. Inflammatory bone loss: pathogenesis and therapeutic intervention. Nat Rev Drug Discov. 2012;11(3):234–250.
  • Santos LCP, de Moraes AN, Saito ME. Effects of intraarticular ropivacaine and morphine on lipopolysaccharide-induced synovitis in horses. Vet Anaesth Analg. 2009;36(3):280–286.
  • Liu X, Zhao P, Ge W. Knockdown of circular RNA circZNF652 remits LPS-induced inflammatory damage by regulating miR-181a. Biofactors. 2020;46(6):1031–1040.
  • Scotece M, Conde J, Abella V, et al. Oleocanthal inhibits catabolic and inflammatory mediators in LPS-activated human primary osteoarthritis (OA) chondrocytes through MAPKs/NF-κB pathways. Cell Physiol Biochem. 2018;49(6):2414–2426.
  • Goldring MB, Otero M. Inflammation in osteoarthritis. Curr Opin Rheumatol. 2011;23(5):471–478.
  • Blanco FJ, Guitian RN, VZquez-Martul E, et al. Osteoarthritis chondrocytes die by apoptosis: a possible pathway for osteoarthritis pathology. Arthritis Rheum. 1998;41(2):284–289.
  • Pérez-García S, Carrión M, Gutiérrez-Cañas I, et al. Profile of matrix-remodeling proteinases in osteoarthritis: impact of fibronectin. Cells. 2019;9(1):40.
  • Yamada KM, Araki M. Tumor suppressor PTEN: modulator of cell signaling, growth, migration and apoptosis. J Cell Sci. 2001;114(Pt 13):2375–2382.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.