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AC-Autoimmunity: Celebrating 35 Years

Increased IgD and CD27 Double Negative (DN) B cell population in pediatric onset autoimmune hepatitis

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Article: 2356089 | Received 04 Jun 2023, Accepted 12 May 2024, Published online: 21 May 2024

References

  • Mack CL, Adams D, Assis DN, et al. Diagnosis and management of autoimmune hepatitis in adults and children: 2019 practice guidance and guidelines from the American association for the study of liver diseases. Hepatology. 2020;72(2):671–722.
  • Gregorio GV, Portmann B, Reid F, et al. Autoimmune hepatitis in childhood: a 20-year experience. Hepatology. 1997;25(3):541–547.
  • Gregorio GV, Portmann B, Karani J, et al. Autoimmune hepatitis/sclerosing cholangitis overlap syndrome in childhood: a 16-year prospective study. Hepatology. 2001;33(3):544–553.
  • Boberg KM. Prevalence and epidemiology of autoimmune hepatitis. Clin Liver Dis. 2002;6:635–647.
  • Wong RJ, Gish R, Frederick T, et al. The impact of race/ethnicity on the clinical epidemiology of autoimmune hepatitis. J Clin Gastroenterol. 2012;46(2):155–161.
  • Zolfino T, Heneghan MA, Norris S, et al. Characteristics of autoimmune hepatitis in patients who are not of european caucasoid ethnic origin. Gut. 2002;50(5):713–717.
  • Lee WS, Lum SH, Lim CB, et al. Characteristics and outcome of autoimmune liver disease in Asian children. Hepatol Int. 2015;9(2):292–302.
  • Than NN, Jeffery HC, Oo YH. Autoimmune hepatitis: progress from global immunosuppression to personalised regulatory T cell therapy. Can J Gastroenterol Hepatol. 2016;2016:7181685.
  • Taylor SA, Assis DN, Mack CL. The contribution of B cells in autoimmune liver diseases. Semin Liver Dis. 2019;39(4):422–431.
  • Patel AM, Liu YS, Davies SP, et al. The role of B cells in adult and paediatric liver injury. Front Immunol. 2021;12:729143.
  • Chen K, Xu W, Wilson M, et al. Immunoglobulin D enhances immune surveillance by activating antimicrobial, proinflammatory and B cell-stimulating programs in basophils. Nat Immunol. 2009;10(8):889–898.
  • Liu C, Zhang P, Zhang W. Immunological mechanism of IgG4-related disease. J Transl Autoimmun. 2020;3:100047.
  • Palle SK, Naik KB, McCracken CE, et al. Racial disparities in presentation and outcomes of paediatric autoimmune hepatitis. Liver Int. 2019;39:976–984.
  • Jenks SA, Cashman KS, Zumaquero E, et al. Distinct effector B cells induced by unregulated toll-like receptor 7 contribute to pathogenic responses in systemic lupus erythematosus. Immunity. 2018;49(4):725–739 e6.
  • Burak KW, Swain MG, Santodomingo-Garzon T, et al. Rituximab for the treatment of patients with autoimmune hepatitis who are refractory or intolerant to standard therapy. Can J Gastroenterol. 2013;27(5):273–280.
  • Tipton CM, Fucile CF, Darce J, et al. Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus. Nat Immunol. 2015;16(7):755–765.
  • Oracki SA, Walker JA, Hibbs ML, et al. Plasma cell development and survival. Immunol Rev. 2010;237(1):140–159.
  • Hammarlund E, Thomas A, Amanna IJ, et al. Plasma cell survival in the absence of B cell memory. Nat Commun. 2017;8(1):1781.
  • Lonial S, Dimopoulos M, Palumbo A, et al. Elotuzumab therapy for relapsed or refractory multiple myeloma. N Engl J Med. 2015;373(7):621–631.
  • Vergani D, Mieli-Vergani G, Mondelli M, et al. Immunoglobulin on the surface of isolated hepatocytes is associated with antibody-dependent cell-mediated cytotoxicity and liver damage. Liver. 1987;7(6):307–315.
  • Manns M, Zanger U, Gerken G, et al. Patients with type II autoimmune hepatitis express functionally intact cytochrome P-450 db1 that is inhibited by LKM-1 autoantibodies in vitro but not in vivo. Hepatology. 1990;12(1):127–132.
  • Muratori L, Parola M, Ripalti A, et al. Liver/kidney microsomal antibody type 1 targets CYP2D6 on hepatocyte plasma membrane. Gut. 2000;46(4):553–561.
  • Schramm C, Herkel J, Beuers U, et al. Pregnancy in autoimmune hepatitis: outcome and risk factors. Am J Gastroenterol. 2006;101:556–560.
  • Liu X, Jiang X, Liu R, et al. B cells expressing CD11b effectively inhibit CD4+ T-cell responses and ameliorate experimental autoimmune hepatitis in mice. Hepatology. 2015;62(5):1563–1575.
  • Lübbering D, Preti M, Schlott L, et al. Autoantigen-selected B cells are bystanders in spontaneous T cell-driven experimental autoimmune hepatitis. Immunology. 2023;170(2):214–229.
  • Buitrago-Molina LE, Dywicki J, Noyan F, et al. Anti-CD20 therapy alters the protein signature in experimental murine AIH, but not exclusively towards regeneration. Cells. 2021;10(6):1471.