98
Views
1
CrossRef citations to date
0
Altmetric
Original Articles

Immunotoxicological effects triggered by the rattlesnake Crotalus durissus cumanensis, mapanare (Bothrops colombiensis) venoms and its purified fractions on spleen and lymph nodes cells

, & ORCID Icon
Pages 484-492 | Received 02 May 2020, Accepted 07 Aug 2020, Published online: 02 Sep 2020

References

  • Rengifo C, Rodríguez-Acosta A. Serpientes, venenos y su tratamiento en Venezuela. Caracas, Venezuela: Fondo de Publicaciones de la Facultad de Medicina de la Universidad Central de Venezuela; 2005. p. 1–82.
  • Hernandez M, Scannone H, Finol HJ, et al. Alterations in the ultrastructure of cardiac autonomic nervous system triggered by crotoxin from rattlesnake (Crotalus durissus cumanensis) venom. Exp Toxicol Pathol. 2007;59(2):129–137.
  • Aguilar I, Guerrero B, Salazar AM, et al. Individual venom variability in the South American rattlesnake Crotalus durissus cumanensis. Toxicon. 2007;50(2):214–224.
  • Salazar AM, Aguilar I, Guerrero B, et al. Intraspecies differences in hemostatic venom activities of the South America rattlesnakes, Crotalus durissus cumanensis, as revealed by a range of protease inhibitors. Blood Coagul Fibrinol. 2008;19(6):525–530.
  • Calvete JJ, Sanz L, Cid P, et al. Snake venomics of the Central American rattlesnake Crotalus simus and the South American Crotalus durissus complex points to neurotoxicity as an adaptive paedomorphic trend along Crotalus dispersal in South America. J Proteome Res. 2010;9(1):528–544.
  • Fraenkel-Conrat H, Fraenkel-Conrat J. Inactivation of crotoxin by group-specific reagents. Biochim Biophys Acta. 1950;5(1):98–104.
  • Bon C, Bouchier C, Choumet V, et al. Crotoxin, half-century of investigations onphospholipase A2 neurotoxin. Acta Physiol Pharmacol Latinoam. 1989;39(4):439–448.
  • Costa ES, Faiad OJ, Landgraf RG, et al. Involvement of formyl peptide receptors in the stimulatory effect of crotoxin on macrophages co-cultivated with tumour cells. Toxicon. 2013;74:167–178.
  • Delves PJ, Roitt IM. The immune system. Second of two parts. N Engl J Med. 2000;343(2):108–117.
  • National Institutes of Health. Principles of laboratory animal care. Bethesda (MD): NIH; 1985.
  • Pulido-Méndez M, Azuaje BE. Efecto diferencial del veneno crudo y de la crotoxina del Crotalus durissus cumanensis sobre la respuesta proliferativa linfocitaria. LIX Convención Anual de la Asociación Venezolana para el Avance de la Ciencia (ASOVAC). Yuanlin City, Taiwan: Merida, Venezuela; 2009.
  • Rangel-Santos A, Lima C, Lopes-Ferreira M, et al. Immunosuppresive role of principal toxin (crotoxin) of Crotalus durissus terrificus venom. Toxicon. 2004;44(6):609–616.
  • Romero-Vargas FF, Ponce-Soto LA, Martins-de-Souza D, et al. Biological and biochemical characterization of two new PLA2 isoforms Cdc-9 and Cdc-10 from Crotalus durissus cumanensis snake venom. Comp Biochem Physiol C Toxicol Pharmacol. 2010;151(1):66–74.
  • Pereañez JA, Núñez V, Huancahuire-Vega S, et al. Biochemical and biological characterization of a PLA2 from crotoxin complex of Crotalus durissus cumanensis. Toxicon. 2009;53(5):534–542.
  • da Silva RJ, da Silva MG, Vilela LC, et al. Antitumor effect of Bothrops jararaca venom. Mediators Inflamm. 2002;11(2):99–104.
  • Vieira-Santos MM, da Silva RJ, da Silva MG, et al. Subpopulations of mononuclear leukocytes associated with inhibition of Ehrlich ascites tumor growth by treatment with Bothrops jararaca venom. Mediators Inflamm. 2004;13(1):29–32.
  • Castro FR, Farias AS, Proença PL, et al. The effect of treatment with crotapotin on the evolution of experimental autoimmune neuritis induced in Lewis rats. Toxicon. 2007;49(3):299–305.
  • Galan JA, Sánchez EE, Rodríguez-Acosta A, et al. Inhibition of lung tumor colonization and cell migration with the disintegrin crotatroxin 2 isolated from the venom of Crotalus atrox. Toxicon. 2008;51(7):1186–1196.
  • Sánchez EE, Rodríguez-Acosta A, Palomar R, et al. Colombistatin: a disintegrin isolated from the venom of the South American snake (Bothrops colombiensis) that effectively inhibits platelet aggregation and SK-Mel-28 cell adhesion. Arch Toxicol. 2009;83(3):271–279.
  • Costa-Torres AF, Dantas RT, Toyama MH, et al. Antibacterial and antiparasitic effects of Bothrops marajoensis venom and its fractions: phospholipase A2 and L-amino acid oxidase. Toxicon. 2010;55(4):795–804.
  • Rodríguez-Acosta A, Sánchez EE, Márquez A, et al. Hemostatic properties of Venezuelan Bothrops snake venoms with special reference to Bothrops isabelae venom. Toxicon. 2010;56(6):926–935.
  • Seoane AI, Tran VL, Sanchez EE, et al. The mojastin mutant Moj-DM induces apoptosis of the human melanoma SK-Mel-28, but not the mutant Moj-NN nor the non-mutated recombinant Moj-WN. Toxicon. 2010;56(3):391–401.
  • Xie Q, Tang N, Wan R, et al. Recombinant snake venom cystatin inhibits the growth, invasion and metastasis of B16F10 cells and MHCC97H cells in vitro and in vivo. Toxicon. 2011;57(5):704–711.
  • Clissa PB, Laing GD, Theakston RD, et al. The effect of jararhagin, a metalloproteinase from Bothrops jararaca venom, on pro-inflammatory cytokines released by murine peritoneal adherent cells. Toxicon. 2001;39(10):1567–1573.
  • Barraviera B, Lomonte B, Tarkowski A, et al. Acute-phase reactions, including cytokines, in patients bitten by Bothrops and Crotalus snakes in Brazil. J Venom Anim Toxins. 1995;1(1):11–22.
  • Petricevich VL, Teixeira CF, Tambourgi DV, et al. Increments in serum cytokine and nitric oxide levels in mice injected with Bothrops asper and Bothrops jararaca snake venoms. Toxicon. 2000;38(9):1253–1266.
  • Avila-Aguero ML, Paris MM, Hu S, et al. Snakebite study group. Systemic cytokine response in children bitten by snakes in Costa Rica. Ped Emerg Care. 2001;17(6):425–429.
  • Cardoso DF, Lopes-Ferreira M, Faquim-Mauro EL, et al. Role of crotoxin, a phospholipase A2 isolated from Crotalus durissus terrificus snake venom, on inflammatory and immune reactions. Mediators Inflamm. 2001;10(3):125–133.
  • Hernandez-Cruz S, Garcia-Jimenez R, Zucatelli-Mendonc A, et al. Pro- and anti-inflammatory cytokines release in mice injected with Crotalus durissus terrificus Venom. Mediators Inflamm. 2008;2008;874962.
  • Zouari-Kessentini R, Luis J, Karray A, et al. Two purified and characterized phospholipases A2 from Cerastes cerastes venom, that inhibit cancerous cell adhesion and migration. Toxicon. 2009;53(4):444–453.
  • Garcia F, Toyama MH, Castro FR, et al. Crotapotin induced modification of T lymphocyte proliferative response through interference with PGE2 synthesis. Toxicon. 2003;42(4):433–437.
  • Corrêa MC, Maria DA, Moura-da-Silva AM, et al. Inhibition of melanoma cells tumorigenicity by the snake venom toxin jararhagin. Toxicon. 2002;40(6):739–748.
  • Moura-da-Silva AM, Baldo C. Jararhagin, a hemorrhagic snake venom metalloproteinase from Bothrops jararaca. Toxicon. 2012;60(3):280–289.
  • Landucci ECT, Antunes E, Donato JL, et al. Inhibition of carrageenin-induced rat paw oedema by crotapotin, a polypeptide complexed with phospholipase A2. Br J Pharmacol. 1995;114(3):578–583.
  • Landucci ECT, Toyama M, Marangoni S, et al. Effect of crotapotin and heparin on the rat paw oedema induced by different secretory phospholipases A2. Toxicon. 2000;38(2):199–208.
  • Freitas AP, Favoretto BC, Clissa PB, et al. Crotoxin isolated from Crotalus durissus terrificus venom modulates the functional activity of dendritic cells via formyl peptide receptors. J Immunol Res. 2018;2018:7873257.
  • Zambelli VO, Sampaio SC, Sudo-Hayashi LS, et al. Crotoxin alters lymphocyte distribution in rats: involvement of adhesion molecules and lipoxygenase-derived mediators. Toxicon. 2008;51(8):1357–1367.
  • Azevedo E, Gassmann Figueiredo R, Vieira Pinto R, et al. Evaluation of systemic inflammatory response and lung injury induced by Crotalus durissus cascavella venom. PLoS One. 2020;15(2):e0224584.
  • Sampaio SC, Alba-Loureiro TC, Brigatte P, et al. Lipoxygenase-derived eicosanoids are involved in the inhibitory effect of Crotalus durissus terrificus venom or crotoxin on rat macrophage phagocytosis. Toxicon. 2006;47(3):313–321.
  • Mackessy SP. The field of reptile toxinology. Snakes, lizards, and their venoms. In: Mackessy SP, editor. Handbook of venoms and toxins of reptiles. Boca Raton (FL): CRC Press/Taylor & Francis Group; 2010. p. 3–23.
  • Sueyoshi K, Ledderose C, Shen Y, et al. Lipopolysaccharide suppresses T cells by generating extracellular ATP that impairs their mitochondrial function via P2Y11 receptors. J Biol Chem. 2019;294(16):6283–6293.
  • Cura JE, Blanzaco DP, Brisson C, et al. Phase I and pharmacokinetics study of crotoxin (cytotoxic PLA(2), NSC-624244) in patients with advanced cancer. Clin Cancer Res. 2002;8(4):1033–1041.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.