miR-155-5p/FOXO3a promotes pulmonary fibrosis in rats by mediating NLRP3 inflammasome activation

References

• Kolahian S, Fernandez IE, Eickelberg O, et al. Immune mechanisms in pulmonary fibrosis. Am J Respir Cell Mol Biol. 2016;55(3):309–322.
   PubMed Web of Science ®Google Scholar
• Thannickal VJ, Toews GB, White ES, et al. Mechanisms of pulmonary fibrosis. Annu Rev Med. 2004;55:395–417.
   PubMed Web of Science ®Google Scholar
• Martinez FJ, Collard HR, Pardo A, et al. Idiopathic pulmonary fibrosis. Nat Rev Dis Primers. 2017;3:17074.
   PubMed Web of Science ®Google Scholar
• Noble PW, Barkauskas CE, Jiang D. Pulmonary fibrosis: patterns and perpetrators. J Clin Invest. 2012;122(8):2756–2762.
   PubMed Web of Science ®Google Scholar
• Meyer KC. Pulmonary fibrosis, part I: epidemiology, pathogenesis, and diagnosis. Expert Rev Respir Med. 2017;11(5):343–359.
   PubMed Web of Science ®Google Scholar
• Richeldi L, Collard HR, Jones MG. Idiopathic pulmonary fibrosis. Lancet. 2017;389(10082):1941–1952.
   PubMed Web of Science ®Google Scholar
• Sundarakrishnan A, Chen Y, Black LD, et al. Engineered cell and tissue models of pulmonary fibrosis. Adv Drug Deliv Rev. 2018;129:78–94.
   PubMed Web of Science ®Google Scholar
• Gasse P, Riteau N, Charron S, et al. Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosis. Am J Respir Crit Care Med. 2009;179(10):903–913.
   PubMed Web of Science ®Google Scholar
• Li X, Yan X, Wang Y, et al. NLRP3 inflammasome inhibition attenuates silica-induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells. Exp Cell Res. 2018;362(2):489–497.
   PubMed Web of Science ®Google Scholar
• Tian R, Zhu Y, Yao J, et al. NLRP3 participates in the regulation of EMT in bleomycin-induced pulmonary fibrosis. Exp Cell Res. 2017;357(2):328–334.
   PubMed Web of Science ®Google Scholar
• Abderrazak A, Syrovets T, Couchie D, et al. NLRP3 inflammasome: from a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases. Redox Biol. 2015;4:296–307.
   PubMed Web of Science ®Google Scholar
• Bushati N, Cohen SM. microRNA functions. Annu Rev Cell Dev Biol. 2007;23:175–205.
   PubMed Web of Science ®Google Scholar
• Pandit KV, Milosevic J, Kaminski N. MicroRNAs in idiopathic pulmonary fibrosis. Transl Res. 2011;157(4):191–199.
   PubMed Web of Science ®Google Scholar
• Maciak K, Dziedzic A, Miller E, et al. miR-155 as an important regulator of multiple sclerosis pathogenesis. A review. Int J Mol Sci. 2021;22:4332.
   PubMed Web of Science ®Google Scholar
• O’Connell RM, Kahn D, Gibson WS, et al. MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development. Immunity. 2010;33(4):607–619.
   PubMed Web of Science ®Google Scholar
• Vigorito E, Perks KL, Abreu-Goodger C, et al. microRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity. 2007;27(6):847–859.
   PubMed Web of Science ®Google Scholar
• Artlett CM, Sassi-Gaha S, Hope JL, et al. Mir-155 is overexpressed in systemic sclerosis fibroblasts and is required for NLRP3 inflammasome-mediated collagen synthesis during fibrosis. Arthritis Res Ther. 2017;19(1):144.
   PubMedGoogle Scholar
• Li C, Yin W, Yu N, et al. miR-155 promotes macrophage pyroptosis induced by Porphyromonas gingivalis through regulating the NLRP3 inflammasome. Oral Dis. 2019;25(8):2030–2039.
   PubMed Web of Science ®Google Scholar
• Wang Y, Feng T, Duan S, et al. miR-155 promotes fibroblast-like synoviocyte proliferation and inflammatory cytokine secretion in rheumatoid arthritis by targeting FOXO3a. Exp Ther Med. 2020;19:1288–1296.
   PubMed Web of Science ®Google Scholar
• Wu D, Liang M, Dang H, et al. Hydrogen protects against hyperoxia-induced apoptosis in type II alveolar epithelial cells via activation of PI3K/akt/Foxo3a signaling pathway. Biochem Biophys Res Commun. 2018;495(2):1620–1627.
   PubMed Web of Science ®Google Scholar
• Liu T, De Los Santos FG, Phan SH. The bleomycin model of pulmonary fibrosis. Methods Mol Biol. 2017;1627:27–42.
   PubMedGoogle Scholar
• Xiong Y, Nie D, Liu S, et al. Apoptotic PET imaging of rat pulmonary fibrosis with [(18)F]ML-8. Mol Imaging. 2018;17:153601211879572. 1536012118795728.
   Web of Science ®Google Scholar
• Gao R, Shi H, Chang S, et al. The selective NLRP3-inflammasome inhibitor MCC950 reduces myocardial fibrosis and improves cardiac remodeling in a mouse model of myocardial infarction. Int Immunopharmacol. 2019;74:105575.
   PubMed Web of Science ®Google Scholar
• Zhu F, Li H, Liu Y, et al. miR-155 antagomir protect against DSS-induced colitis in mice through regulating Th17/treg cell balance by Jarid2/wnt/beta-catenin. Biomed Pharmacother. 2020;126:109909.
   PubMed Web of Science ®Google Scholar
• Liu YM, Lv J, Zeng QL, et al. AMPK activation ameliorates D-GalN/LPS-induced acute liver failure by upregulating Foxo3A to induce autophagy. Exp Cell Res. 2017;358(2):335–342.
   PubMed Web of Science ®Google Scholar
• Gu X, Wu G, Yao Y, et al. Intratracheal administration of mitochondrial DNA directly provokes lung inflammation through the TLR9-p38 MAPK pathway. Free Radic Biol Med. 2015;83:149–158.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Li X, Grailer JJ, et al. Melatonin alleviates acute lung injury through inhibiting the NLRP3 inflammasome. J Pineal Res. 2016;60(4):405–414.
   PubMed Web of Science ®Google Scholar
• Suda K, Kitagawa Y, Ozawa S, et al. Anti-high-mobility group box chromosomal protein 1 antibodies improve survival of rats with sepsis. World J Surg. 2006;30(9):1755–1762.
   PubMed Web of Science ®Google Scholar
• Szapiel SV, Elson NA, Fulmer JD, et al. Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse. Am Rev Respir Dis. 1979;120(4):893–899.
   PubMed Web of Science ®Google Scholar
• Lv Z, Wang Y, Liu YJ, et al. NLRP3 inflammasome activation contributes to mechanical Stretch-Induced Endothelial-Mesenchymal transition and pulmonary fibrosis. Crit Care Med. 2018;46(1):e49–e58.
   PubMed Web of Science ®Google Scholar
• Snijder J, Peraza J, Padilla M, et al. Pulmonary fibrosis: a disease of alveolar collapse and collagen deposition. Expert Rev Respir Med. 2019;13(7):615–619.
   PubMed Web of Science ®Google Scholar
• Kang H. Role of MicroRNAs in TGF-beta signaling Pathway-Mediated pulmonary fibrosis. Int J Mol Sci. 2017;18:2527.
   PubMed Web of Science ®Google Scholar
• Elliott EI, Sutterwala FS. Initiation and perpetuation of NLRP3 inflammasome activation and assembly. Immunol Rev. 2015;265(1):35–52.
   PubMed Web of Science ®Google Scholar
• Zahid A, Li B, Kombe AJK, et al. Pharmacological inhibitors of the NLRP3 inflammasome. Front Immunol. 2019;10(2538):2538.
   PubMedGoogle Scholar
• Lasithiotaki I, Giannarakis I, Tsitoura E, et al. NLRP3 inflammasome expression in idiopathic pulmonary fibrosis and rheumatoid lung. Eur Respir J. 2016;47(3):910–918.
   PubMed Web of Science ®Google Scholar
• Li Y, Li H, Liu S, et al. Pirfenidone ameliorates lipopolysaccharide-induced pulmonary inflammation and fibrosis by blocking NLRP3 inflammasome activation. Mol Immunol. 2018;99:134–144.
   PubMed Web of Science ®Google Scholar
• Liang Q, Cai W, Zhao Y, et al. Lycorine ameliorates bleomycin-induced pulmonary fibrosis via inhibiting NLRP3 inflammasome activation and pyroptosis. Pharmacol Res. 2020;158:104884.
   PubMed Web of Science ®Google Scholar
• Wang D, Liu Z, Yan Z, et al. MiRNA-155-5p inhibits epithelium-to-mesenchymal transition (EMT) by targeting GSK-3beta during radiation-induced pulmonary fibrosis. Arch Biochem Biophys. 2021;697:108699.
   PubMed Web of Science ®Google Scholar
• Yin R, Zhu X, Wang J, et al. MicroRNA-155 promotes the ox-LDL-induced activation of NLRP3 inflammasomes via the ERK1/2 pathway in THP-1 macrophages and aggravates atherosclerosis in ApoE-/- mice. Ann Palliat Med. 2019;8(5):676–689.
   PubMed Web of Science ®Google Scholar
• Im J, Hergert P, Nho RS. Reduced FoxO3a expression causes low autophagy in idiopathic pulmonary fibrosis fibroblasts on collagen matrices. Am J Physiol Lung Cell Mol Physiol. 2015;309(6):L552–561.
   PubMed Web of Science ®Google Scholar
• Zhou L, Li P, Zhang M, et al. Carbon black nanoparticles induce pulmonary fibrosis through NLRP3 inflammasome pathway modulated by miR-96 targeted FOXO3a. Chemosphere. 2020;241:125075.
   PubMed Web of Science ®Google Scholar
• Wu X, Chang SC, Jin J, et al. NLRP3 in fl ammasome mediates chronic intermittent hypoxia-induced renal injury implication of the microRNA-155/FOXO3a signaling pathway. J Cell Physiol. 2018;233(12):9404–9415.
   PubMed Web of Science ®Google Scholar
• Wree A, Eguchi A, McGeough MD, et al. NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice. Hepatology. 2014;59(3):898–910.
   PubMed Web of Science ®Google Scholar