The protective effect of butylated hydroxytoluene and 3-hydroxytyrosol on food allergy in mice

References

• Gupta RS, Warren CM, Smith BM, et al. Prevalence and severity of food allergies among US adults. JAMA Netw Open. 2019;2(1):e185630.
   PubMed Web of Science ®Google Scholar
• Sicherer SH, Sampson HA. Food allergy: a review and update on epidemiology, pathogenesis, diagnosis, prevention, and management. J Allergy Clin Immunol. 2018;141(1):41–58.
   PubMed Web of Science ®Google Scholar
• Dunlop JH, Keet CA. Epidemiology of food allergy. Immunol Allergy Clin North Am. 2018;38(1):13–25.
   PubMed Web of Science ®Google Scholar
• Ebisawa M, Ito K, Fujisawa T, Committee for Japanese Pediatric Guideline for Food Allergy, The Japanese Society of Pediatric Allergy and Clinical Immunology, The Japanese Society of Allergology. Japanese guidelines for food allergy 2017. Allergol Int. 2017;66(2):248–264.
   PubMed Web of Science ®Google Scholar
• Loh W, Tang MLK. The epidemiology of food allergy in the global context. Int J Environ Res Public Health. 2018;15(9):2043.
   PubMed Web of Science ®Google Scholar
• Sampson HA, O'Mahony L, Burks AW, et al. Mechanisms of food allergy. J Allergy Clin Immunol. 2018;141(1):11–19.
   PubMed Web of Science ®Google Scholar
• Satitsuksanoa P, Jansen K, Głobińska A, et al. Regulatory immune mechanisms in tolerance to food. Front Immunol. 2018;9:2939.
   PubMed Web of Science ®Google Scholar
• Benede S, Blazquez AB, Chiang D, et al. The rise of food allergy: environmental factors and emerging treatments. EBioMedicine. 2016 May;7:27–34.
   PubMed Web of Science ®Google Scholar
• De Martinis M, Sirufo MM, Suppa M, et al. New perspectives in food allergy. Int J Mol Sci. 2020;21(4):21.
   Web of Science ®Google Scholar
• Valenta R, Hochwallner H, Linhart B, et al. Food allergies: the basics. Gastroenterology. 2015;148(6):1120–1131 e4.
   PubMed Web of Science ®Google Scholar
• Zukiewicz-Sobczak WA, Wroblewska P, Adamczuk P, et al. Causes, symptoms and prevention of food allergy. Postepy Dermatol Alergol. 2013;30(2):113–116. Apr
   PubMed Web of Science ®Google Scholar
• Oria MP, Stallings VA, editors. Finding a path to safety in food allergy: assessment of the global burden, causes, prevention, management, and public policy. Washington (DC): National Academies Press; 2016.
   Google Scholar
• Murr C, Schroecksnadel K, Winkler C, et al. Antioxidants may increase the probability of developing allergic diseases and asthma. Med Hypotheses. 2005;64(5):973–977.
   PubMed Web of Science ®Google Scholar
• Zaknun D, Schroecksnadel S, Kurz K, et al. Potential role of antioxidant food supplements, preservatives and colorants in the pathogenesis of allergy and asthma. Int Arch Allergy Immunol. 2012;157(2):113–124.
   PubMed Web of Science ®Google Scholar
• Aune D. Plant foods, antioxidant biomarkers, and the risk of cardiovascular disease, cancer, and mortality: a review of the evidence. Adv Nutr. 2019;10(Suppl_4):S404–S421.
   PubMedGoogle Scholar
• Aune D, Keum N, Giovannucci E, et al. Dietary intake and blood concentrations of antioxidants and the risk of cardiovascular disease, total cancer, and all-cause mortality: a systematic review and dose-response meta-analysis of prospective studies. Am J Clin Nutr. 2018;108(5):1069–1091.
   PubMed Web of Science ®Google Scholar
• Griffiths K, Aggarwal BB, Singh RB, et al. Food antioxidants and their anti-Inflammatory properties: a potential role in cardiovascular diseases and cancer prevention. Diseases. 2016;4(4):28.
   PubMedGoogle Scholar
• Keranis E, Makris D, Rodopoulou P, et al. Impact of dietary shift to higher-antioxidant foods in COPD: a randomised trial. Eur Respir J. 2010;36(4):774–780. Oct
   PubMed Web of Science ®Google Scholar
• Varadharaj S, Kelly OJ, Khayat RN, et al. Role of dietary antioxidants in the preservation of vascular function and the modulation of health and disease. Front Cardiovasc Med. 2017;4:64.
   PubMed Web of Science ®Google Scholar
• Allan K, Kelly FJ, Devereux G. Antioxidants and allergic disease: a case of too little or too much? Clin Exp Allergy. 2010;40(3):370–380.
   PubMed Web of Science ®Google Scholar
• Dash DK, Dash M, Dash B, et al. Association of dietary pattern on asthma and allergic disorders: an observational hospital based study [antioxidant levels, asthma, junk foods, Lacto ovo vegetarian, non-vegetarian]. 2016;4(1):7.
   Google Scholar
• Moreno-Macias H, Romieu I. Effects of antioxidant supplements and nutrients on patients with asthma and allergies. J Allergy Clin Immunol. 2014;133(5):1237–1244; quiz 1245.
   PubMed Web of Science ®Google Scholar
• Goodman DL, McDonnell JT, Nelson HS, et al. Chronic urticaria exacerbated by the antioxidant food preservatives, butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT). J Allergy Clin Immunol. 1990;86(4 Pt 1):570–575.
   PubMed Web of Science ®Google Scholar
• Weber RW. Adverse reactions to the antioxidants butylated hydroxyanisole and butylated hydroxytoluene. In: Dean D, Metcalfe MD, Hugh A, et al. editors. Food Allergy: adverse reactions to foods and food additives. 5th ed. Chichester, England: John Wiley & Sons, Ltd; 2013. p. 393–401.
   Google Scholar
• Winkler C, Schroecksnadel K, Schennach H, et al. Vitamin C and E suppress mitogen-stimulated peripheral blood mononuclear cells in vitro. Int Arch Allergy Immunol. 2007;142(2):127–132.
   PubMed Web of Science ®Google Scholar
• Wirleitner B, Schroecksnadel K, Winkler C, et al. Resveratrol suppresses interferon-gamma-induced biochemical pathways in human peripheral blood mononuclear cells in vitro. Immunol Lett. 2005;100(2):159–163.
   PubMed Web of Science ®Google Scholar
• Birmingham N, Payankaulam S, Thanesvorakul S, et al. An ELISA-based method for measurement of food-specific IgE antibody in mouse serum: an alternative to the passive cutaneous anaphylaxis assay. J Immunol Methods. 2003;275(1-2):89–98.
   PubMed Web of Science ®Google Scholar
• Jin Y, Ebaugh S, Martens A, et al. A mouse model of anaphylaxis and atopic dermatitis to Salt-Soluble wheat protein extract. Int Arch Allergy Immunol. 2017;174(1):7–16.
   PubMed Web of Science ®Google Scholar
• Miyaji K, Okamoto N, Saito A, et al. Cross-reactivity between major IgE core epitopes on cry j 2 allergen of japanese cedar pollen and relevant sequences on cha o 2 allergen of Japanese cypress pollen. Allergol Int. 2016;65(3):286–292. Jul
   PubMed Web of Science ®Google Scholar
• Birmingham N, Gangur V, Samineni S, et al. Hazelnut allergy: evidence that hazelnut can directly elicit specific IgE antibody response via activating type 2 cytokines in mice. Int Arch Allergy Immunol. 2005;137(4):295–302. Aug
   PubMed Web of Science ®Google Scholar
• Gonipeta B, Para R, He Y, et al. Cardiac mMCP-4+ mast cell expansion and elevation of IL-6, and CCR1/3 and CXCR2 signaling chemokines in an adjuvant-free mouse model of tree nut allergy. Immunobiology. 2015;220(5):663–672.
   PubMed Web of Science ®Google Scholar
• Hannuksela M, Haahtela T. Hypersensitivity reactions to food additives. Allergy. 1987;42(8):561–575.
   PubMed Web of Science ®Google Scholar
• Lucas JS, Lewis SA, Hourihane JO. Kiwi fruit allergy: a review. Pediatr Allergy Immunol. 2003;14(6):420–428.
   PubMed Web of Science ®Google Scholar
• Roehr CC, Edenharter G, Reimann S, et al. Food allergy and non-allergic food hypersensitivity in children and adolescents. Clin Exp Allergy. 2004;34(10):1534–1541. Oct
   PubMed Web of Science ®Google Scholar
• Valluzzi RL, Fierro V, Arasi S, et al. Allergy to food additives. Curr Opin Allergy Clin Immunol. 2019;19(3):256–262.
   PubMed Web of Science ®Google Scholar
• Nieva-Echevarria B, Manzanos MJ, Goicoechea E, et al. 2,6-Di-Tert-Butyl-Hydroxytoluene and its metabolites in foods. Comprehensive Rev Food Sci Food Safety. 2015;14(1):67–80.
   PubMed Web of Science ®Google Scholar
• Yehye WA, Rahman NA, Ariffin A, et al. Understanding the chemistry behind the antioxidant activities of butylated hydroxytoluene (BHT): a review. Eur J Med Chem. 2015;101:295–312.
   PubMed Web of Science ®Google Scholar
• Additives EPoF Food NSat. Scientific opinion on the re-evaluation of butylated hydroxytoluene BHT (E 321) as a food additive. Efsa J. 2012;10(3):2588.
   Google Scholar
• Evaluation of national intake assessments of butylated hydroxytoluene. Geneva: FAO/WHO. 2021https://inchem.org/documents/jecfa/jecmono/v042je24.htm
   Google Scholar
• Martínez L, Ros G, Nieto G. Hydroxytyrosol: health benefits and use as functional ingredient in meat. Medicines. 2018;5(1):13.
   Google Scholar
• Silva AFR, Resende D, Monteiro M, et al. Application of hydroxytyrosol in the functional foods field: from ingredient to dietary supplements. Antioxidants. 2020;9(12):1246.
   Web of Science ®Google Scholar
• FDA. GRAS notice (GRN) no. 600 for hydroxytyrosol. Vero Beach (FL): FDA. 2021. https://www.fda.gov/media/96937/download
   Google Scholar
• Gref A, Rautiainen S, Gruzieva O, et al. Dietary total antioxidant capacity in early school age and subsequent allergic disease. Clin Exp Allergy. 2017;47(6):751–759.
   PubMed Web of Science ®Google Scholar
• Litonjua AA, Rifas-Shiman SL, Ly NP, et al. Maternal antioxidant intake in pregnancy and wheezing illnesses in children at 2 y of age. Am J Clin Nutr. 2006;84(4):903–911.
   PubMed Web of Science ®Google Scholar
• Rubin RN, Navon L, Cassano PA. Relationship of serum antioxidants to asthma prevalence in youth. Am J Respir Crit Care Med. 2004;169(3):393–398.
   PubMed Web of Science ®Google Scholar
• Alwarith J, Kahleova H, Crosby L, et al. The role of nutrition in asthma prevention and treatment. Nutr Rev. 2020;78(11):928–938.
   PubMed Web of Science ®Google Scholar
• Bokhari J, Khan MR. Evaluation of anti-asthmatic and antioxidant potential of boerhavia procumbens in toluene diisocyanate (TDI) treated rats. J Ethnopharmacol. 2015;172:377–385.
   PubMed Web of Science ®Google Scholar
• Boskabady MH, Farkhondeh T. Antiinflammatory, antioxidant, and immunomodulatory effects of crocus sativus L. and its main constituents. Phytother Res. 2016;30(7):1072–1094.
   PubMed Web of Science ®Google Scholar
• McGowan SE, Holmes AJ, Smith J. Retinoic acid reverses the airway hyperresponsiveness but not the parenchymal defect that is associated with vitamin a deficiency. Am J Physiol Lung Cell Mol Physiol. 2004;286(2):L437–L444.
   PubMed Web of Science ®Google Scholar
• Patel BD, Welch AA, Bingham SA, et al. Dietary antioxidants and asthma in adults. Thorax. 2006;61(5):388–393.
   PubMed Web of Science ®Google Scholar
• Liang Z, Wu L, Deng X, et al. The antioxidant rosmarinic acid ameliorates oxidative lung damage in experimental allergic asthma via modulation of NADPH oxidases and antioxidant enzymes. Inflammation. 2020;43(5):1902–1912. Oct
   PubMed Web of Science ®Google Scholar
• Nadeem A, Masood A, Siddiqui N. Oxidant–antioxidant imbalance in asthma: scientific evidence, epidemiological data and possible therapeutic options. Ther Adv Respir Dis. 2008;2(4):215–235.
   PubMedGoogle Scholar
• Fogarty A, Lewis S, Weiss S, et al. Dietary vitamin E, IgE concentrations, and atopy. Lancet. 2000;356(9241):1573–1574.
   PubMed Web of Science ®Google Scholar
• Fogarty A, Lewis SA, Scrivener SL, et al. Oral magnesium and vitamin C supplements in asthma: a parallel group randomized placebo-controlled trial. Clin Exp Allergy. 2003;33(10):1355–1359.
   PubMed Web of Science ®Google Scholar