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Biofouling
The Journal of Bioadhesion and Biofilm Research
Volume 36, 2020 - Issue 10
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Research Article

Effect of xylitol tablets with and without red propolis on salivary parameters, dental biofilm and sensory acceptability of adolescents: a randomized crossover clinical trial

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Pages 1182-1195 | Received 24 Sep 2020, Accepted 24 Nov 2020, Published online: 17 Dec 2020

References

  • Aires CP, Del Bel Cury AA, Tenuta LM, Klein MI, Koo H, Duarte S, Cury JA. 2008. Effect of starch and sucrose on dental biofilm formation and on root dentine demineralization. Caries Res. 42:380–386. doi:10.1159/000154783
  • Almaz ME, Sönmez IŞ, Ökte Z, Oba AA. 2017. Efficacy of a sugar-free herbal lollipop for reducing salivary Streptococcus mutans levels: a randomized controlled trial. Clin Oral Investig. 21:839–845. doi:10.1007/s00784-016-1827-y
  • Aluckal E, Ankola AV. 2018. Effectiveness of xylitol and polyol chewing gum on salivary Streptococcus mutans in children: a randomized controlled trial. Indian J Dent Res. 29:445–449. doi:10.4103/ijdr.IJDR_307_16
  • Anauate-Netto C, Anido-Anido A, Lewgoy HR, Matsumoto R, Alonso RCB, Marcucci MC, Paulino N, Bretz WA. 2014. Randomized, double-blind, placebo-controlled clinical trial on the effects of propolis and chlorhexidine mouthrinses on gingivitis. BDS. 17:11–15. doi:10.14295/bds.2014.v17i1.947
  • Antonio AG, Pierro VS, Maia LC. 2011. Caries preventive effects of xylitol-based candies and lozenges: a systematic review. J Public Health Dent. 71:117–124. doi:10.1111/j.1752-7325.2010.00208.x
  • Arat Maden E, Altun C, Açikel C. 2017. The efficacy of xylitol, xylitol-probiotic and fluoride dentifrices in plaque reduction and gingival inflammation in children: a randomised controlled clinical trial. Oral Health Prev Dent. 15:117–121. 10.3290/j.ohpd.a37973.
  • Ayres M, Ayres Júnior M, Ayres DL, Santos AS. 2007. BioEstat 5.0: Aplicações estatísticas nas areas das ciências biológicas e médicas [BioEstat 5.0: statistical applications in the areas of biological and medical sciences]. MCT, IDSM, CNPq, Belém, p. 364. Available from: https://www.mamiraua.org.br/pt-/publicacoes/publicacoes/2007/livros/bioestat-50/.
  • Brown JP, Amaechi BT, Bader JD, Gilbert GH, Makhija SK, Lozano-Pineda J, Leo MC, Chen C, Vollmer WM, X-ACT Trial Collaborative Group. 2014. Visual scoring of non cavitated caries lesions and clinical trial efficiency, testing xylitol in caries-active adults. Community Dent Oral Epidemiol. 42:271–278. doi:10.1111/cdoe.12082
  • Bueno-Silva B, Koo H, Falsetta ML, Alencar SM, Ikegaki M, Rosalen PL. 2013. Effect of neovestitol-vestitol containing Brazilian red propolis on accumulation of biofilm in vitro and development of dental caries in vivo. Biofouling. 29:1233–1242. doi:10.1080/08927014.2013.834050
  • Bueno-Silva B, Marsola A, Ikegaki M, Alencar SM, Rosalen PL. 2017. The effect of seasons on Brazilian red propolis and its botanical source: chemical composition and antibacterial activity. Nat Prod Res. 31:1318–1324. doi:10.1080/14786419.2016.1239088
  • Cagetti MG, Cocco F, Carta G, Maspero C, Campus G. 2020. Long-term efficacy of magnolia bark extract and xylitol administered through chewing gums on caries in adults: a 2-year randomized controlled intervention trial. J Funct Foods. 68:103891. doi:10.1016/j.jff.2020.103891
  • Campus G, Cagetti MG, Cocco F, Sale S, Sacco G, Strohmenger L, Lingström P. 2011. Effect of a sugar-free chewing gum containing magnolia bark extract on different variables related to caries and gingivitis: a randomized controlled intervention trial. Caries Res. 45:393–399. doi:10.1159/000330234
  • Cardoso JG, Iorio NLP, Rodrigues LF, Couri MLB, Farah A, Maia LC, Antonio AG. 2016. Influence of a Brazilian wild green propolis on the enamel mineral loss and Streptococcus mutans' count in dental biofilm. Arch Oral Biol. 65:77–81. doi:10.1016/j.archoralbio.2016.02.001
  • Cocco F, Carta G, Cagetti MG, Strohmenger L, Lingström P, Campus G. 2017. The caries preventive effect of 1-year use of low-dose xylitol chewing gum. A randomized placebo-controlled clinical trial in high-caries-risk adults. Clin Oral Invest. 21:2733–2740. doi:10.1007/s00784-017-2075-5
  • Cunha MG, Franchin M, Paula-Eduardo LF, Freires IA, Beutler JA, Alencar SM, Ikegaki M, Tabchoury CPM, Cunha TM, Rosalen PL. 2016. Anti-inflammatory and anti-biofilm properties of ent-nemorosone from Brazilian geopropolis. J Funct Foods. 26:27–35. doi:10.1016/j.jff.2016.07.009
  • Da Mata AD, Marques DNS, Silveira JM, Marques JR, Felino ETMC, Guilherme NF. 2009. Effects of gustatory stimulants of salivary secretion on salivary pH and flow: a randomized controlled trial. Oral Dis. 15:220–228. doi:10.1111/j.1601-0825.2009.01513.x
  • Dalmagro MF, Rossi RC, De Souza D, Castilhos J, Pontin B. 2015. Xerostomia: desenvolvimento de uma bala com potencial sialogogo [Xerostomia: development of a bullet with sialogogue potential]. Saúde e Desenvolvimento Humano. 3:35–44. doi:10.18316/2317-8582.15.3
  • Daugsch A, Moraes CS, Fort P, Park YK. 2008. Brazilian red propolis-chemical composition and botanical origin. Evid Based Complement Alternat Med. 5:435–441. doi:10.1093/ecam/nem057
  • Dubois M, Gilles KA, Hamilton JK, Rebers PA, Smith F. 1956. Colorimetric method for determination of sugars and related substances. Anal Chem. 28:350–356. doi:10.1021/ac60111a017
  • Dutcosky SD. 2013. Análise sensorial de alimentos. 4th ed. Curitiba: Champagnat, p. 531. ≪Editor: AQ: please give title in English as well≫
  • Ericsson Y. 1959. Clinical investigation of the salivary buffering action. Acta Odontol Scand. 17:131–165. doi:10.3109/00016355908993928
  • Feferbaum R, de Abreu LC, Leone C. 2012. Fluid intake patterns: an epidemiological study among children and adolescents in Brazil. BMC Public Health. 12:1005. doi:10.1186/1471-2458-12-1005
  • Fejerskov O. 2004. Changing paradigms in concepts on dental caries: consequences for oral health care. Caries Res. 38:182–191. doi:10.1159/000077753
  • Feldens CA, Kramer Pf, Vargas-Ferreira F. 2019. The role of diet and oral hygiene in dental caries. In: Leal SC, Takeshita EM, editors. Pediatric restorative dentistry. Cham: Springer; p. 31–55.
  • Filoche S, Wong L, Sissons CH. 2010. Oral biofilms: emerging concepts in microbial ecology. J Dent Res. 89:8–18. doi:10.1177/0022034509351812
  • Freires IA, Rosalen PL. 2016. How Natural product research has contributed to oral care product development? A critical view. Pharm Res. 33:1311–1317. doi:10.1007/s11095-016-1905-5
  • García-Soidán JL, Leirós-Rodríguez R, Romo-Pérez V, Arufe-Giráldez V. 2020. Evolution of the habits of physical activity and television viewing in Spanish children and pre-adolescents between 1997 and 2017. IJERPH. 17:6836. doi:10.3390/ijerph17186836
  • Habryka C, Socha R, Juszczak L. 2020. The effect of enriching honey with propolis on the antioxidant activity, sensory characteristics, and quality parameters. Molecules. 25:1176. doi:10.3390/molecules25051176
  • Jeon JG, Rosalen PL, Falsetta ML, Koo H. 2011. Natural products in caries research: current (limited) knowledge, challenges and future perspective. Caries Res. 45:243–263. doi:10.1159/000327250
  • Jepsen S, Blanco J, Buchalla W, Carvalho JC, Dietrich T, Dörfer C, Eaton KA, Figuero E, Frencken JE, Graziani F, et al. 2017. Prevention and control of dental caries and periodontal diseases at individual and population level: consensus report of group 3 of joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases. J Clin Periodontol. 44 Suppl 18:S85–S93. doi:10.1111/jcpe.12687
  • Kakuta H, Iwami Y, Mayanagi H, Takahashi N. 2003. Xylitol inhibition of acid production and growth of mutans streptococci in the presence of various dietary sugars under strictly anaerobic conditions. Caries Res. 37:404–409. doi:10.1159/000073391
  • Lagerweij MD, van Loveren C. 2015. Declining caries trends: are we satisfied? Curr Oral Health Rep. 2:212–217. doi:10.1007/s40496-015-0064-9
  • Lee Y, Choi Y, Jeong S, Kim H, Lee S, Song K. 2009. Morphological changes in Streptococcus mutans after chewing gum containing xylitol for twelve months. Curr Microbiol. 58:332–337. doi:10.1007/s00284-008-9332-4
  • Ly KA, Milgrom P, Roberts MC, Yamaguchi DK, Rothen M, Mueller G. 2006. Linear response of mutans streptococci to increasing frequency of xylitol chewing gum use: a randomized controlled trial. BMC Oral Health.6:6. doi:10.1186/1472-6831-6-6
  • Madrona G, D, Silva DF, Vital ACP, D, Santos SS, Scapim MS. 2016. Desenvolvimento e avaliação de sorvete com substâncias desintoxicantes [Development and evaluation of ice cream with detoxifying substances]. Rev Engenh Tecnol. 8:78–87.
  • Marsh PD. 2004. Dental plaque as a microbial biofilm. Caries Res. 38:204–211. doi:10.1159/000077756
  • Martins C, Siqueira WL, Oliveira E, Primo LSSG, Nicolau J. 2006. Salivary analysis of patients with chronic renal failure undergoing hemodialysis. Spec Care in Dent. 26:205–208. doi:10.1111/j.1754-4505.2006.tb01439.x
  • Martins ML, Leite KLF, Pacheco-Filho EF, Pereira AFM, Romanos MTV, Maia LC, Fonseca-Gonçalves A, Padilha WWN, Cavalcanti YW. 2018. Efficacy of red propolis hydro-alcoholic extract in controlling Streptococcus mutans biofilm build-up and dental enamel demineralization. Arch Oral Biol. 93:56–65. doi:10.1016/j.archoralbio.2018.05.017
  • Martins ML, Coelho MO, F, Filho JCC, Vieira TI, Guimarães MBCT, Maia LC, Cavalcanti YW, Fonseca-Gonçalves A. 2018. Efeito de uma pastilha de própolis no pH salivar e contagem de microrganismos do biofilme dental de crianças e adolescentes: um estudo piloto [Effect of a propolis tablet on salivary pH and microorganism count of dental biofilm in children and adolescents: a pilot study]. In: 35a Reunião Anual da SBPqO, 2018, Campinas. 35a Reunião Anual da SBPqO. 32; p. 344.
  • Martins ML, Monteiro ASN, Ferreira-Filho JCC, Vieira TI, Guimarães MBCT, Farah A, Romanos MTV, Maia LC, Cavalcanti YW, Fonseca-Gonçalves A. 2019. Antibacterial and cytotoxic potential of a Brazilian red propolis. Pesqui Bras Odontopediatria Clín Integr. 19:e4626–e4629. doi:10.4034/PBOCI.2019.191.93
  • Martins ML, Monteiro ASN, Guimarães JEC, Guimarães MBCT, da Silva RF, Cabral LM, Farah A, dePaula J, Romanos MTV, Maia LC, et al. 2019. Cytotoxic and antibacterial effect of a red propolis mouthwash, with or without fluoride, on the growth of a cariogenic biofilm. Arch Oral Biol. 107:104512. doi:10.1016/j.archoralbio.2019.104512
  • Moher D, Hopewell S, Schulz KF, Montori V, Gotzsche PC, Devereaux PJ, Elbourne D, Egger M, Altman DG. 2010. CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. BMJ. 340:c869. doi:10.1136/bmj.c869
  • Murray MC, Worthington HV, Blinkhorn AS. 1997. A study to investigate the effect of a propolis-containing mouthrinse on the inhibition of de novo plaque formation. J Clin Periodontol. 24:796–798. doi:10.1111/j.1600-051x.1997.tb01191.x
  • Nuuja T, Meurman JH, Murtomaa H, Kortelainen S, Metteri J. 1992. The effect of a combination of chlorhexidine diacetate, sodium fluoride and xylitol on plaque wet weight and periodontal index scores in military academy cadets refraining from mechanical tooth cleaning for 7-day experimental periods. J Clin Periodontol. 19:73–76. doi:10.1111/j.1600-051x.1992.tb00443.x
  • Olivier P, Testard P, Marzin D, Abbott D. 1995. Effect of high polyol concentrations on the neutral red absorption assay and tetrazolium-MTT test of rat hepatocytes in primary culture. Toxicol in Vitro. 9:133–138. https://doi.org/10.1016/0887-2333.(94)00209-D. doi:10.1016/0887-2333(94)00209-D
  • Oza S, Patel K, Bhosale S, Mitra R, Gupta R, Choudhary D. 2018. To determine the effect of chewing gum containing xylitol and sorbitol on mutans streptococci and Lactobacilli count in saliva, plaque, and gingival health and to compare the efficacy of chewing gums. J Int Soc Prev Community Dent. 8:354–360. doi:10.4103/jispcd.JISPCD_54_18
  • Pimenta MS, Lobo NSG, Vieira VC, Costa AMA, Costa FN, Pereira SLS. 2016. Effect of Ocimum gratissimum in mouthrinses on de novo plaque formation. A randomized clinical trial. Braz Dent J. 27:646–651. doi:10.1590/0103-6440201601331
  • Riley P, Moore D, Ahmed F, Sharif MO, Worthington HV. 2015. Xylitol-containing products for preventing dental caries in children and adults (Review). Cochrane Database Syst Rev. 3:CD010743. doi:10.1002/14651858.CD010743.pub2
  • Simón-Soro A, Mira A. 2015. Solving the etiology of dental caries. Trends Microbiol. 23:76–82. doi:10.1016/j.tim.2014.10.010
  • Takahashi N, Nyvad B. 2011. The role of bacteria in the caries process: ecological perspectives. J Dent Res. 90:294–303. doi:10.1177/0022034510379602
  • Singhal N, Kumar M, Kanaujia PK, Virdi JS. 2015. MALDI-TOF mass spectrometry: an emerging technology for microbial identification and diagnosis. Front Microbiol. 5:791. doi:10.3389/fmicb.2015.00791
  • Tulsani SG, Chikkanarasaiah N, Siddaiah SB, Krishnamurthy NH. 2014. The effect of propolis and xylitol chewing gums on salivary Streptococcus mutans count: a clinical trial. Indian J Dent Res. 25:737–741. Available from: http://www.ijdr.in/text.asp?2014/25/6/737/152182. doi:10.4103/0970-9290.152182
  • Rodrigues IC, de Oliveira DB, de Menezes PB, da Costa FN, Carlos MX, Pereira SD. 2013. Effect of Lippia sidoides in mouthrinses on de novo plaque formation: a double-blind clinical study in humans. Indian J Dent Res. 24:533–536. Available from: http://www.ijdr.in/text.asp?2013/24/5/533/123360. doi:10.4103/0970-9290.123360
  • Rafeek R, Carrington CVF, Gomez A, Harkins D, Torralba M, Kuelbs C, Addae J, Moustafa A, Nelson KE. 2019. Xylitol and sorbitol effects on the microbiome of saliva and plaque. J Oral Microbiol. 11:1536181. doi:10.1080/20002297.2018.1536181
  • Sintes JL, Escalante C, Stewart B, McCool JJ, Garcia L, Volpe AR, Triol C. 1995. Enhanced anticaries efficacy of a 0.243% sodium fluoride/10% xylitol/silica dentifrice: 3-year clinical results. Am J Dent. 8:231–235.
  • Söderling E, ElSalhy M, Honkala E, Fontana M, Flannagan S, Eckert G, Kokaras A, Paster B, Tolvanen M, Honkala S. 2015. Effects of short-term xylitol gum chewing on the oral microbiome. Clin Oral Investig. 19:237–244. doi:10.1007/s00784-014-1229-y
  • Talavera K, Ninomiya Y, Winkel C, Voets T, Nilius B. 2007. Influence of temperature on taste perception. Cell Mol Life Sci. 64:377–381. 10.1007/s00018-006-6384-0.
  • World Health Organization (WHO). 1997. Oral health surveys: basic methods. 4th ed. Geneva: World Health Organization.
  • World Health Organization (WHO). 2013. Definition of key terms. Age groups and populations. Consolidated ARV guidelines, June. Available from: https://www.who.int/hiv/pub/guidelines/arv2013/intro/keyterms/en/.

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