New developments in anti-biofilm intervention towards effective management of orthopedic device related infections (ODRI’s)

References

• Abdulkareem EH, Memarzadeh K, Allaker RP, Huang J, Pratten J, Spratt D. 2015. Anti-biofilm activity of zinc oxide and hydroxyapatite nanoparticles as dental implant coating materials. J Dent. 43:1462–1469. doi:10.1016/j.jdent.2015.10.010
   PubMed Web of Science ®Google Scholar
• Abedon ST. 2015. Ecology of anti-biofilm agents II: bacteriophage exploitation and biocontrol of biofilm bacteria. Pharmaceuticals (Basel)). 8:559–589. doi:10.3390/ph8030559
   PubMedGoogle Scholar
• Abedon ST. 2016b. Bacteriophage exploitation of bacterial biofilms: phage preference for less mature targets? FEMS Microbiol Lett. 363:fnv246. 10.1093/femsle/fnv246. doi:10.1093/femsle/fnv246
   PubMed Web of Science ®Google Scholar
• Abisado RG, Benomar S, Klaus JR, Dandekar AA, Chandler JR. 2018. Bacterial quorum sensing and microbial communityi interactions. mBio. 9:e02331. doi:10.1128/mBio.01749-18
   PubMed Web of Science ®Google Scholar
• Alkawash MA, Soothill JS, Schiller NL. 2006. Alginate lyase enhances antibiotic killing of mucoid Pseudomonas aeruginosa in biofilms. APMIS. 114:131–138. doi:10.1111/j.1600-0463.2006.apm_356.x
   PubMed Web of Science ®Google Scholar
• Andersson DI, Hughes D, Kubicek-Sutherland JZ. 2016. Mechanisms and consequences of bacterial resistance to antimicrobial peptides. Drug Resist Updat. 26:43–57. doi:10.1016/j.drup.2016.04.002
   PubMed Web of Science ®Google Scholar
• Annunziata M, Canullo L, Donnarumma G, Caputo P, Nastri L, Guida L. 2016. Bacterial inactivation/sterilization by argon plasma treatment on contaminated titanium implant surfaces: in vitro study. Med Oral Patol Oral Cir Bucal. 21:e118–e121. doi:10.4317/medoral.20845
   PubMed Web of Science ®Google Scholar
• Ansari MA, Khan HM, Khan AA, Cameotra SS, Saquib Q, Musarrat J. 2014. Interaction of Al2O3 nanoparticles with Escherichia coli and their cell envelope biomolecules. J Appl Microbiol. 116(4):772–783. doi:10.1111/jam.12423
   PubMed Web of Science ®Google Scholar
• Antoci V, Adams CS, Parvizi J, Davidson HM, Composto RJ, Freeman TA, Wickstrom E, Ducheyne P, Jungkind D, Shapiro IM, et al. 2008. The inhibition of Staphylococcus epidermidis biofilm formation by vancomycin-modified titanium alloy and implications for the treatment of periprosthetic infection. Biomaterials. 29:4684–4690. doi:10.1016/j.biomaterials.2008.08.016
   PubMed Web of Science ®Google Scholar
• Antoci V, Jr, Adams CS, Parvizi J, Ducheyne P, Shapiro IM, Hickok NJ. 2007. Covalently attached vancomycin provides a nanoscale antibacterial surface. Clin Orthop Relat Res. 461:81–87. doi:10.1097/BLO.0b013e3181123a50
   PubMedGoogle Scholar
• Arciola CR, Campoccia D, Ehrlich GD, Montanaro L. 2015. Biofilm-based implant infections in orthopaedics. Adv Exp Med Biol. 830:29–46. doi:10.1007/978-3-319-11038-7_2
   PubMed Web of Science ®Google Scholar
• Arciola CR, Campoccia D, Montanaro L. 2018. Implant infections: adhesion, biofilm formation and immune evasion. Nat Rev Microbiol. 16:397–409. doi:10.1038/s41579-018-0019-y
   PubMed Web of Science ®Google Scholar
• Aslam S, Pretorius V, Lehman SM, Morales S, Schooley RT. 2019. Novel bacteriophage therapy for treatment of left ventricular assist device infection. J Heart Lung Transplant. 38:475–476. doi:10.1016/j.healun.2019.01.001
   PubMed Web of Science ®Google Scholar
• Azeredo J, Sutherland IW. 2008. The use of phages for the removal of infectious biofilms. Curr Pharm Biotechnol. 9:261–266. doi:10.2174/138920108785161604
   PubMed Web of Science ®Google Scholar
• Baidamshina DR, Trizna EY, Holyavka MG, Bogachev MI, Artyukhov VG, Akhatova FS, Rozhina EV, Fakhrullin RF, Kayumov AR. 2017. Targeting microbial biofilms using Ficin, a nonspecific plant protease. Sci Rep. 7:46068. doi:10.1038/srep46068
   PubMed Web of Science ®Google Scholar
• Balaban N, Cirioni O, Giacometti A, Ghiselli R, Braunstein JB, Silvestri C, Mocchegiani F, Saba V, Scalise G. 2007. Treatment of Staphylococcus aureus biofilm infection by the quorum-sensing inhibitor RIP. Antimicrob Agents Chemother. 51:2226–2229. doi:10.1128/AAC.01097-06
   PubMed Web of Science ®Google Scholar
• Balaban N, Giacometti A, Cirioni O, Gov Y, Ghiselli R, Mocchegiani F, Viticchi C, Del Prete MS, Saba V, Scalise G, et al. 2003. Use of the quorum-sensing inhibitor RNAIII-inhibiting peptide to prevent biofilm formation in vivo by drug-resistant Staphylococcus epidermidis. J Infect Dis. 187:625–630. doi:10.1086/345879
   PubMed Web of Science ®Google Scholar
• Banar M, Emaneini M, Beigverdi R, Fanaei Pirlar R, Node Farahani N, van Leeuwen WB, Jabalameli F. 2019. The efficacy of lyticase and β-glucosidase enzymes on biofilm degradation of Pseudomonas aeruginosa strains with different gene profiles. BMC Microbiol. 19:291. doi:10.1186/s12866-019-1662-9
   PubMed Web of Science ®Google Scholar
• Batoni G, Maisetta G, Brancatisano FL, Esin S, Campa M. 2011. Use of antimicrobial peptides against microbial biofilms: advantages and limits. Curr Med Chem. 18:256–279. doi:10.2174/092986711794088399
   PubMed Web of Science ®Google Scholar
• Batoni G, Maisetta G, Esin S. 2016. Antimicrobial peptides and their interaction with biofilms of medically relevant bacteria. Biochim Biophys Acta. 1858:1044–1060. doi:10.1016/j.bbamem.2015.10.013
   PubMed Web of Science ®Google Scholar
• Bernthal NM, Stavrakis AI, Billi F, Cho JS, Kremen TJ, Simon SI, Cheung AL, Finerman GA, Lieberman JR, Adams JS, et al. 2010. A mouse model of post-arthroplasty Staphylococcus aureus joint infection to evaluate in vivo the efficacy of antimicrobial implant coatings. PLoS One. 5:e12580. doi:10.1371/journal.pone.0012580
   PubMed Web of Science ®Google Scholar
• Bistolfi A, Massazza G, Verné E, Massè A, Deledda D, Ferraris S, Miola M, Galetto F, Crova M. 2011. Antibiotic-loaded cement in orthopedic surgery: a review. ISRN Orthop. 2011:290851. doi:10.5402/2011/290851
   PubMedGoogle Scholar
• Biswas A, Bayer IS, Biris AS, Wang T, Dervishi E, Faupel F. 2012. Advances in top-down and bottom-up surface nanofabrication: techniques, applications & future prospects. Adv Colloid Interface Sci. 170:2–27. doi:10.1016/j.cis.2011.11.001
   PubMed Web of Science ®Google Scholar
• Biswas B, Adhya S, Washart P, Paul B, Trostel AN, Powell B, Carlton R, Merril CR. 2002. Bacteriophage therapy rescues mice bacteremic from a clinical isolate of vancomycin-resistant Enterococcus faecium. Infect Immun. 70:204–210. doi:10.1128/iai.70.1.204-210.2002
   PubMed Web of Science ®Google Scholar
• Biswas R, Voggu L, Simon UK, Hentschel P, Thumm G, Gotz F. 2006. Activity of the major staphylococcal autolysin Atl. FEMS Microbiol Lett. 259:260–268. doi:10.1111/j.1574-6968.2006.00281.x
   PubMed Web of Science ®Google Scholar
• Bjarnsholt T, van Gennip M, Jakobsen TH, Christensen LD, Jensen PØ, Givskov M. 2010. In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect. Nat Protoc. 5:282–293. doi:10.1038/nprot.2009.205
   PubMed Web of Science ®Google Scholar
• Bloemen M, Brullot W, Luong TT, Geukens N, Gils A, Verbiest T. 2012. Improved functionalization of oleic acid-coated iron oxide nanoparticles for biomedical applications. J Nanopart Res. 14:1100. doi:10.1007/s11051-012-1100-5
   PubMed Web of Science ®Google Scholar
• Bozic KJ, Katz P, Cisternas M, Ono L, Ries MD, Showstack J. 2005. Hospital resource utilization for primary and revision total hip arthroplasty. J Bone Joint Surg Am. 87:570–576.
   PubMed Web of Science ®Google Scholar
• Bozic KJ, Ries MD. 2005. The impact of infection after total hip arthroplasty on hospital and surgeon resource utilization. J Bone Joint Surg Am. 87:1746–1751. doi:10.2106/JBJS.D.02937
   PubMed Web of Science ®Google Scholar
• Brackman G, Coenye T. 2015. Quorum sensing inhibitors as anti-biofilm agents. Curr Pharm Des. 21:5–11. doi:10.2174/1381612820666140905114627
   PubMed Web of Science ®Google Scholar
• Brackman G, Cos P, Maes L, Nelis HJ, Coenye T. 2011b. Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo. Antimicrob Agents Chemother. 55:2655–2661. doi:10.1128/AAC.00045-11
   PubMed Web of Science ®Google Scholar
• Brady AJ, Laverty G, Gilpin DF, Kearney P, Tunney M. 2017. Antibiotic susceptibility of planktonic- and biofilm-grown staphylococci isolated from implant-associated infections: should MBEC and nature of biofilm formation replace MIC? J Med Microbiol. 66:461–469. doi:10.1099/jmm.0.000466 PMID: 28463662.
   PubMed Web of Science ®Google Scholar
• Brancatisano FL, Maisetta G, Di Luca M, Esin S, Bottai D, Bizzarri R, Campa M, Batoni G. 2014. Inhibitory effect of the human liver-derived antimicrobial peptide hepcidin 20 on biofilms of polysaccharide intercellular adhesin (PIA)-positive and PIA-negative strains of Staphylococcus epidermidis. Biofouling. 30:435–446. doi:10.1080/08927014.2014.888062
   PubMed Web of Science ®Google Scholar
• Broekhuizen CAN, de Boer L, Schipper K, Jones CD, Quadir S, Feldman RG, Dankert J, Vandenbroucke-Grauls CMJE, Weening JJ, Zaat SAJ. 2007. Peri-implant tissue is an important niche for Staphylococcus epidermidis in experimental biomaterial-associated infection in mice. Infect Immun. 75:1129–1136. doi:10.1128/IAI.01262-06
   PubMed Web of Science ®Google Scholar
• Brown AN, Smith K, Samuels TA, Lu J, Obare SO, Scott ME. 2012. Nanoparticles functionalized with ampicillin destroy multiple-antibiotic-resistant isolates of Pseudomonas aeruginosa and Enterobacter aerogenes and methicillin-resistant Staphylococcus aureus. Appl Environ Microbiol. 78:2768–2774. doi:10.1128/AEM.06513-11
   PubMed Web of Science ®Google Scholar
• Buchegger S, Kamenac A, Fuchs S, Herrmann R, Houdek P, Gorzelanny C, Obermeier A, Heller S, Burgkart R, Stritzker B, et al. 2019. Smart antimicrobial efficacy employing pH-sensitive ZnO-doped diamond-like carbon coatings. Sci Rep. 9:17246. doi:10.1038/s41598-019-53521-7
   PubMed Web of Science ®Google Scholar
• Bulman ZP, Ly NS, Lenhard JR, Holden PN, Bulitta JB, Tsuji BT. 2017. Influence of rhlR and lasR on polymyxin pharmacodynamics in Pseudomonas aeruginosa and implications for quorum sensing inhibition with azithromycin. Antimicrob Agents Chemother. 61:e00096. doi:10.1128/AAC.00096-16
   PubMed Web of Science ®Google Scholar
• Busscher HJ, Alt V, van der Mei HC, Fagette PH, Zimmerli W, Moriarty TF, Parvizi J, Schmidmaier G, Raschke MJ, Gehrke T, et al. 2019. A trans-Atlantic perspective on stagnation in clinical translation of antimicrobial strategies for the control of biomaterial-implant-associated infection. ACS Biomater Sci Eng. 5:402–406. doi:10.1021/acsbiomaterials.8b01071
   PubMed Web of Science ®Google Scholar
• Campoccia D, Montanaro L, Arciola CR. 2006. The significance of infection related to orthopedic devices and issues of antibiotic resistance. Biomaterials. 27:2331–2339. doi:10.1016/j.biomaterials.2005.11.044
   PubMed Web of Science ®Google Scholar
• Campoccia D, Speziale P, Ravaioli S, Cangini I, Rindi S, Pirini V, Montanaro L, Arciola CR. 2009. The presence of both bone sialoprotein-binding protein gene and collagen adhesin gene as a typical virulence trait of the major epidemic cluster in isolates from orthopedic implant infections. Biomaterials. 30:6621–6628. doi:10.1016/j.biomaterials.2009.08.032
   PubMed Web of Science ®Google Scholar
• Carpenter AW, Worley BV, Slomberg DL, Schoenfisch MH. 2012. Dual action antimicrobials: nitric oxide release from quaternary ammonium-functionalized silica nanoparticles. Biomacromolecules. 13:3334–3342. doi:10.1021/bm301108x
   PubMed Web of Science ®Google Scholar
• Carter DR, Beaupré GS, Giori NJ, Helms JA. 1998. Mechanobiology of skeletal regeneration. Clin Orthop Relat Res. S41–S55.
   PubMed Web of Science ®Google Scholar
• Chauvin J, Judée F, Yousfi M, Vicendo P, Merbahi N. 2017. Analysis of reactive oxygen and nitrogen species generated in three liquid media by low temperature helium plasma jet. Sci Rep. 7:4562. doi:10.1038/s41598-017-04650-4
   PubMed Web of Science ®Google Scholar
• Chen CH, Lu TK. 2020. Development and challenges of antimicrobial peptides for therapeutic applications. Antibiotics (Basel). 9:24. doi:10.3390/antibiotics9010024
   Web of Science ®Google Scholar
• Chen CP, Wickstrom E. 2010. Self-protecting bactericidal titanium alloy surface formed by covalent bonding of daptomycin bisphosphonates. Bioconjug Chem. 21:1978–1986. doi:10.1021/bc100136e
   PubMed Web of Science ®Google Scholar
• Chen J, Shi X, Zhu Y, Chen Y, Gao M, Gao H, Liu L, Wang L, Mao C, Wang Y. 2020. On-demand storage and release of antimicrobial peptides using Pandora's box-like nanotubes gated with a bacterial infection-responsive polymer. Theranostics. 10:109–122. doi:10.7150/thno.38388
   PubMed Web of Science ®Google Scholar
• Chen M, Yu Q, Sun H. 2013. Novel strategies for the prevention and treatment of biofilm related infections. Int J Mol Sci. 14:18488–18501. doi:10.3390/ijms140918488
   PubMed Web of Science ®Google Scholar
• Chen Z, Yu X, Zhang A, Wang F, Xing Y. 2020. De novo hydrocarbon-stapling design of single-turn α-helical antimicrobial peptides. Int J Pept Res Ther. 26:1711–1719.
   Web of Science ®Google Scholar
• Cheng H, Yue K, Kazemzadeh-Narbat M, Liu Y, Khalilpour A, Li B, Zhang YS, Annabi N, Khademhosseini A. 2017. Mussel-inspired multifunctional hydrogel coating for prevention of infections and enhanced osteogenesis. ACS Appl Mater Interfaces. 9:11428–11439. doi:10.1021/acsami.6b16779
   PubMed Web of Science ®Google Scholar
• Chhibber S, Kaur J, Kaur S. 2018. Liposome entrapment of bacteriophages improves wound healing in a diabetic mouse MRSA infection. Front Microbiol. 9:561. doi:10.3389/fmicb.2018.00561
   PubMed Web of Science ®Google Scholar
• Chhibber S, Kaur S, Kumari S. 2008. Therapeutic potential of bacteriophage in treating Klebsiella pneumoniae B5055-mediated lobar pneumonia in mice. J Med Microbiol. 57:1508–1513. doi:10.1099/jmm.0.2008/002873-0
   PubMed Web of Science ®Google Scholar
• Chhibber S, Shukla A, Kaur S. 2017. Transfersomal phage cocktail is an effective treatment against methicillin-resistant Staphylococcus aureus-mediated skin and soft tissue infections. Antimicrob Agents Chemother. 61:e02146–16. doi:10.1128/AAC.02146-16
   PubMed Web of Science ®Google Scholar
• Chiang W-C, Nilsson M, Jensen PØ, Høiby N, Nielsen TE, Givskov M, Tolker-Nielsen T. 2013. Extracellular DNA shields against aminoglycosides in Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother. 57:2352–2361. doi:10.1128/AAC.00001-13
   PubMed Web of Science ®Google Scholar
• Choe H, Narayanan AS, Gandhi DA, Weinberg A, Marcus RE, Lee Z, Bonomo RA, Greenfield EM. 2015. Immunomodulatory peptide IDR-1018 decreases implant infection and preserves osseointegration. Clin Orthop Relat Res. 473:2898–2907. doi:10.1007/s11999-015-4301-2
   PubMed Web of Science ®Google Scholar
• Chou WC, Wang RC, Huang CL, Lee TM. 2018. The effect of plasma treatment on the osseointegration of rough titanium implant: a histo-morphometric study in rabbits. J Dent Sci. 13:267–273. doi:10.1016/j.jds.2018.06.002
   PubMed Web of Science ®Google Scholar
• Chung PY, Khanum R. 2017. Antimicrobial peptides as potential anti-biofilm agents against multidrug-resistant bacteria. J Microbiol Immunol Infect. 50:405–410. doi:10.1016/j.jmii.2016.12.005
   PubMedGoogle Scholar
• Cirioni O, Mocchegiani F, Cacciatore I, Vecchiet J, Silvestri C, Baldassarre L, Ucciferri C, Orsetti E, Castelli P, Provinciali M, et al. 2013. Quorum sensing inhibitor FS3-coated vascular graft enhances daptomycin efficacy in a rat model of staphylococcal infection. Peptides. 40:77–81. doi:10.1016/j.peptides.2012.12.002
   PubMed Web of Science ®Google Scholar
• Cleophas RTC, Riool M, Quarles van Ufford H, Linda C, Zaat SAJ, Kruijtzer JAW. 2014. Convenient preparation of bactericidal hydrogels by covalent attachment of stabilized antimicrobial peptides using thiol–ene click chemistry. ACS Macro Lett. 3:477–480. doi:10.1021/mz5001465
   PubMed Web of Science ®Google Scholar
• Cobb LH, Park J, Swanson EA, Beard MC, McCabe EM, Rourke AS, Seo KS, Olivier AK, Priddy LB. 2019. CRISPR-Cas9 modified bacteriophage for treatment of Staphylococcus aureus induced osteomyelitis and soft tissue infection. PLoS One. 14:e0220421. doi:10.1371/journal.pone.0220421
   PubMed Web of Science ®Google Scholar
• Colon G, Ward BC, Webster TJ. 2006. Increased osteoblast and decreased Staphylococcus epidermidis functions on nanophase ZnO and TiO2. J Biomed Mater Res A. 78:595–604. doi:10.1002/jbm.a.30789
   PubMedGoogle Scholar
• Conlon BP, Geoghegan JA, Waters EM, McCarthy H, Rowe SE, Davies JR, Schaeffer CR, Foster TJ, Fey PD, O'Gara JP. 2014. Role for the A domain of unprocessed accumulation-associated protein (Aap) in the attachment phase of the Staphylococcus epidermidis biofilm phenotype . J Bacteriol. 196:4268–4275. doi:10.1128/JB.01946-14
   PubMed Web of Science ®Google Scholar
• Connaughton A, Childs A, Dylewski S, Sabesan VJ. 2014. Biofilm disrupting technology for orthopedic implants: what's on the horizon? Front Med (Lausanne). 1:22. i doi:10.3389/fmed.2014.00022
   PubMedGoogle Scholar
• Costa F, Carvalho IF, Montelaro RC, Gomes P, Martins MC. 2011. Covalent immobilization of antimicrobial peptides (AMPs) onto biomaterial surfaces. Acta Biomater. 7:1431–1440. doi:10.1016/j.actbio.2010.11.005
   PubMed Web of Science ®Google Scholar
• Costerton JW, Montanaro L, Arciola CR. 2005. Biofilm in implant infections: its production and regulation. Int J Artif Organs. 28:1062–1068. doi:10.1177/039139880502801103
   PubMed Web of Science ®Google Scholar
• Costerton JW, Stewart PS, Greenberg EP. 1999. Bacterial biofilms: a common cause of persistent infections. Science. 284:1318–1322. doi:10.1126/science.284.5418.1318
   PubMed Web of Science ®Google Scholar
• Cramton SE, Gerke C, Schnell NF, Nichols WW, Gotz F. 1999. The intercellular adhesion (ica) locus is present in Staphylococcus aureus and is required for biofilm formation. Infect Immun. 67:5427–5433. doi:10.1128/IAI.67.10.5427-5433.1999
   PubMed Web of Science ®Google Scholar
• Crockarell JR, Hanssen AD, Osmon DR, Morrey BF. 1998. Treatment of infection with débridement and retention of the components following hip arthroplasty. J Bone Joint Surg Am. 80:1306–1313. doi:10.2106/00004623-199809000-00009
   PubMed Web of Science ®Google Scholar
• Cui Y, Zhao Y, Tian Y, Zhang W, Lü X, Jiang X. 2012. The molecular mechanism of action of bactericidal gold nanoparticles on Escherichia coli. Biomaterials. 33:2327–2333. doi:10.1016/j.biomaterials.2011.11.057
   PubMed Web of Science ®Google Scholar
• Daraee H, Eatemadi A, Abbasi E, Fekri Aval S, Kouhi M, Akbarzadeh A. 2016. Application of gold nanoparticles in biomedical and drug delivery. Artif Cells Nanomed Biotechnol. 44:410–422. doi:10.3109/21691401.2014.955107
   PubMed Web of Science ®Google Scholar
• Darouiche RO. 2004. Treatment of infections associated with surgical implants. N Engl J Med. 350:1422–1429. doi:10.1056/NEJMra035415
   PubMed Web of Science ®Google Scholar
• Darouiche RO, Landon GC, Patti JM, Nguyen LL, Fernau RC, McDevitt D, Greene C, Foster T, Klima M. 1997. Role of Staphylococcus aureus surface adhesins in orthopaedic device infections: are results model-dependent? J Med Microbiol. 46:75–79. doi:10.1099/00222615-46-1-75
   PubMed Web of Science ®Google Scholar
• Darouiche RO, Mansouri MD, Gawande PV, Madhyastha S. 2009. Antimicrobial and anti-biofilm efficacy of triclosan and Dispersin B combination. J Antimicrob Chemother. 64:88–93. doi:10.1093/jac/dkp158
   PubMed Web of Science ®Google Scholar
• Darouiche RO. 2004. Treatment of infections associated with surgical implants. N Engl J Med. 350:1422–1429. doi:10.1056/NEJMra035415
   PubMed Web of Science ®Google Scholar
• Das MC, Sandhu P, Gupta P, Rudrapaul P, De UC, Tribedi P, Akhter Y, Bhattacharjee S. 2016. Attenuation of Pseudomonas aeruginosa biofilm formation by Vitexin: a combinatorial study with azithromycin and gentamicin. Sci Rep. 6:23347. doi:10.1038/srep23347
   PubMed Web of Science ®Google Scholar
• Dastgheyb S, Parvizi J, Shapiro IM, Hickok NJ, Otto M. 2015. Effect of biofilms on recalcitrance of staphylococcal joint infection to antibiotic treatment. J Infect Dis. 211:641–650. doi:10.1093/infdis/jiu514
   PubMed Web of Science ®Google Scholar
• Davidson DJ, Spratt D, Liddle AD. 2019. Implant materials and prosthetic joint infection: the battle with the biofilm. EFORT Open Rev. 4:633–639. doi:10.1302/2058-5241.4.180095
   PubMed Web of Science ®Google Scholar
• Davidson H, Poon M, Saunders R, Shapiro IM, Hickok NJ, Adams CS. 2015. Tetracycline tethered to titanium inhibits colonization by Gram-negative bacteria. J Biomed Mater Res B Appl Biomater. 103:1381–1389. doi:10.1002/jbm.b.33310
   PubMed Web of Science ®Google Scholar
• de Breij A, Riool M, Kwakman PHS, de Boer L, Cordfunke RA, Drijfhout JW, Cohen O, Emanuel N, Zaat SAJ, Nibbering PH, et al. 2016. Prevention of Staphylococcus aureus biomaterial-associated infections using a polymer-lipid coating containing the antimicrobial peptide OP-145. J Control Release. 222:1–8. doi:10.1016/j.jconrel.2015.12.003
   PubMed Web of Science ®Google Scholar
• de la Fuente-Núñez C, Reffuveille F, Mansour SC, Reckseidler-Zenteno SL, Hernández D, Brackman G, Coenye T, Hancock REW. 2015. D-enantiomeric peptides that eradicate wild-type and multidrug-resistant biofilms and protect against lethal Pseudomonas aeruginosa infections. Chem Biol. 22:196–205. doi:10.1016/j.chembiol.2015.01.002
   PubMedGoogle Scholar
• De Lucas-Villarrubia JC, Lopez-Franco M, Granizo JJ, De Lucas-Garcia JC, Gomez-Barrena E. 2004. Strategy to control methicillin-resistant Staphylococcus aureus post-operative infection in orthopaedic surgery. Int Orthop. 28:16–20. doi:10.1007/s00264-003-0460-y
   PubMed Web of Science ®Google Scholar
• Del Pozo JL, Rouse MS, Patel R. 2008. Bioelectric effect and bacterial biofilms. A systematic review. Int J Artif Organs. 31:786–795. doi:10.1177/039139880803100906
   PubMed Web of Science ®Google Scholar
• Delago A, Mandabi A, Meijler MM. 2016. Natural quorum sensing inhibitors–small molecules, big messages. Isr J Chem. 56:310–320. doi:10.1002/ijch.201500052
   Web of Science ®Google Scholar
• DeMeo D, Calogero V, Are L, Cavallo AU, Persiani P, Villani C. 2020. Antibiotic-loaded hydrogel coating to reduce early postsurgical infections in aseptic hip revision surgery: a retrospective, matched case-control study. Microorganisms. 8:571.
   Web of Science ®Google Scholar
• Dhammi IK, Ul Haq R, Kumar S. 2015. Prophylactic antibiotics in orthopedic surgery: controversial issues in its use. Indian J Orthop. 49:373–376. doi:10.4103/0019-5413.159556
   PubMed Web of Science ®Google Scholar
• Di YP, Lin Q, Chen C, Montelaro RC, Doi Y, Deslouches B. 2020. Enhanced therapeutic index of an antimicrobial peptide in mice by increasing safety and activity against multidrug-resistant bacteria. Sci Adv. 6:eaay6817. doi:10.1126/sciadv.aay6817
   PubMed Web of Science ®Google Scholar
• Diefenbeck M, Schrader C, Gras F, Mückley T, Schmidt J, Zankovych S, Bossert J, Jandt KD, Völpel A, Sigusch BW, et al. 2016. Gentamicin coating of plasma chemical oxidized titanium alloy prevents implant-related osteomyelitis in rats. Biomaterials. 101:156–164. doi:10.1016/j.biomaterials.2016.05.039
   PubMed Web of Science ®Google Scholar
• Divakar DD, Jastaniyah NT, Altamimi HG. 2018. Enhanced antimicrobial activity of naturally derived bioactive molecule chitosan conjugated silver nanoparticle against dental implant pathogens. Int J BiolMacromol. 108:790–797. doi:10.1016/j.ijbiomac.2017.10.166
   Google Scholar
• Długosz O, Szostak K, Staroń A, Pulit-Prociak J, Banach M. 2020. Methods for reducing the toxicity of metal and metal oxide NPs as biomedicine. Materials (Basel). 13:279. doi:10.3390/ma13020279
   PubMed Web of Science ®Google Scholar
• Dong Y, Xu Y, Li P, Wang C, Cao Y, Yu J. 2017. Anti-biofilm effect of ultrasound combined with microbubbles against Staphylococcus epidermidis biofilm. Int J Med Microbiol. 307:321–328. doi:10.1016/j.ijmm.2017.06.001
   PubMed Web of Science ®Google Scholar
• Doshi P, Gopalan H, Sprague S, Pradhan C, Kulkarni S, Bhandari M. 2017. Incidence of infection following internal fixation of open and closed tibia fractures in India (INFINITI): a multi-centre observational cohort study. BMC Musculoskelet Disord. 18:156. doi:10.1186/s12891-017-1506-4
   PubMed Web of Science ®Google Scholar
• Doub JB, Ng VY, Johnson AJ, Slomka M, Fackler J, Horne B, Brownstein MJ, Henry M, Malagon F, Biswas B. 2020. Salvage bacteriophage therapy for a chronic MRSA prosthetic joint infection. Antibiotics (Basel). 9:241. doi:10.3390/antibiotics9050241
   Web of Science ®Google Scholar
• Duckworth DH, Gulig PA. 2002. Bacteriophages: potential treatment for bacterial infections. BioDrugs. 16:57–62. doi:10.2165/00063030-200216010-00006
   PubMed Web of Science ®Google Scholar
• Durrieu MC, Pallu S, Guillemot F, Bareille R, Amédée J, Baquey CH, Labrugère C, Dard M. 2004. Grafting RGD containing peptides onto hydroxyapatite to promote osteoblastic cells adhesion. J Mater Sci Mater Med. 15:779–786. doi:10.1023/b:jmsm.0000032818.09569.d9
   PubMed Web of Science ®Google Scholar
• Dusane DH, Lochab V, Jones T, Peters CW, Sindeldecker D, Das A, Roy S, Sen CK, Subramaniam VV, Wozniak DJ, et al. 2019. Electroceutical treatment of Pseudomonas aeruginosa biofilms. Sci Rep. 9:1–13. doi:10.1038/s41598-018-37891-y
   PubMedGoogle Scholar
• Duske K, Koban I, Kindel E, Schroder K, Nebe B, Holtfreter B, Jablonowski L, Weltmann KD, Kocher T. 2012. Atmospheric plasma enhances wettability and cell spreading on dental implant metals. J Clin Periodontol. 39:400–407. doi:10.1111/j.1600-051X.2012.01853.x
   PubMed Web of Science ®Google Scholar
• Ekrami A, Abbasi Montazeri E, Kaydani GA, Shokoohizadeh L. 2015. Methicillin resistant staphylococci: prevalence and susceptibility patterns in a burn center in Ahvaz from 2013-2014. Iran J Microbiol. 7:208–213.
   PubMed Web of Science ®Google Scholar
• El Shazely B, Yu G, Johnston PR, Rolff J. 2020. Resistance evolution against antimicrobial peptides in Staphylococcus aureus alters pharmacodynamics beyond the MIC. Front Microbiol. 11:103. doi:10.3389/fmicb.2020.00103
   PubMed Web of Science ®Google Scholar
• Falugi F, Kim HK, Missiakas DM, Schneewind O. 2013. Role of protein A in the evasion of host adaptive immune responses by Staphylococcus aureus. mBio. 4:e00575–e00513. doi:10.1128/mBio.00575-13
   PubMed Web of Science ®Google Scholar
• Fang FC. 1997. Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity. J Clin Invest. 99:2818–2825. doi:10.1172/JCI119473
   PubMed Web of Science ®Google Scholar
• Fernandes M. d C, Peres LR, de Queiroz AC, Lima JQ, Turíbio FM, Matsumoto MH. 2015. Open fractures and the incidence of infection in the surgical debridement 6 hours after trauma. Acta Ortop Bras. 23:38–42. doi:10.1590/1413-78522015230100932
   PubMed Web of Science ®Google Scholar
• Fleming D, Rumbaugh K. 2018. The consequences of biofilm dispersal on the Host. Sci Rep. 8:10738 doi:10.1038/s41598-018-29121-2
   PubMed Web of Science ®Google Scholar
• Fleming D, Rumbaugh K. 2018. The consequences of biofilm dispersal on the Host. Sci Rep. 8:10738 doi:10.1038/s41598-018-29121-2
   PubMed Web of Science ®Google Scholar
• Fong SA, Drilling A, Morales S. 2017. Activity of bacteriophages in removing bofilms of Pseudomonas aeruginosa isolates from chronic rhinosinusitis patients. Front Cell Infect Microbiol. 7:418.
   PubMed Web of Science ®Google Scholar
• Foster TJ, Geoghegan JA, Ganesh VK, Hook M. 2014. Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus. Nat Rev Microbiol. 12:49–62. doi:10.1038/nrmicro3161.
   PubMed Web of Science ®Google Scholar
• Fu W, Forster T, Mayer O, Curtin JJ, Lehman SM, Donlan RM. 2010. Bacteriophage cocktail for the prevention of biofilm formation by Pseudomonas aeruginosa on catheters in an in vitro model system. Antimicrob Agents Chemother . 54:397–404. doi:10.1128/AAC.00669-09
   PubMed Web of Science ®Google Scholar
• Fulzele SV, Satturwar PM, Dorle AK. 2007. Novel biopolymers as implant matrix for the delivery of ciprofloxacin: biocompatibility, degradation, and in vitro antibiotic release. J Pharm Sci. 96:132–144. doi:10.1002/jps.20730
   PubMed Web of Science ®Google Scholar
• Furfaro LL, Payne MS, Chang BJ. 2018. Bacteriophage therapy: Clinical trials and regulatory hurdles. Front Cell Infect Microbiol.8:376. doi:10.3389/fcimb.2018.00376
   PubMed Web of Science ®Google Scholar
• Garnett JA, Matthews S. 2012. Interactions in bacterial biofilm development: a structural perspective. Curr Protein Pept Sci. 13:739–755. doi:10.2174/138920312804871166
   PubMed Web of Science ®Google Scholar
• Gates BD, Xu Q, Stewart M, Ryan D, Willson CG, Whitesides GM. 2005. New approaches to nanofabrication: molding, printing, and other techniques. Chem Rev. 105:1171–1196. doi:10.1021/cr030076o
   PubMed Web of Science ®Google Scholar
• Genovese EA, Avgerinos ED, Baril DT, Makaroun MS, Chaer RA. 2016. Bio-absorbable antibiotic impregnated beads for the treatment of prosthetic vascular graft infections. Vascular. 24:590–597. doi:10.1177/1708538116630859
   PubMed Web of Science ®Google Scholar
• Gollwitzer H, Ibrahim K, Meyer H, Mittelmeier W, Busch R, Stemberger A. 2003. Antibacterial poly(d, l-lactic acid) coating of medical implants using a biodegradable drug delivery technology. J Antimicrob Chemother. 51:585–591. doi:10.1093/jac/dkg105
   PubMed Web of Science ®Google Scholar
• Goodman SB, Yao Z, Keeney M, Yang F. 2013. The future of biologic coatings for orthopaedic implants. Biomaterials. 34:3174–3183. doi:10.1016/j.biomaterials.2013.01.074
   PubMed Web of Science ®Google Scholar
• Gour A, Jain NK. 2019. Advances in green synthesis of nanoparticles. Artif Cells Nanomed Biotechnol. 47:844–851. doi:10.1080/21691401.2019.1577878
   PubMed Web of Science ®Google Scholar
• Graniel O, Weber M, Balme S, Miele P, Bechelany M. 2018. Atomic layer deposition for biosensing applications. Biosens Bioelectron. 122:147–159. doi:10.1016/j.bios.2018.09.038
   PubMed Web of Science ®Google Scholar
• Gristina AG. 1987. Biomaterial-centered infection: microbial adhesion versus tissue integration. Science. 237:1588–1595. doi:10.1126/science.3629258
   PubMed Web of Science ®Google Scholar
• Guastaldi FPS, Yoo D, Marin C, Jimbo R, Tovar N, Zanetta-Barbosa D, Coelho PG. 2013. Plasma treatment maintains surface energy of the implant surface and enhances osseointegration. Int J Biomater. 2013:1–6. doi:10.1155/2013/354125
   Google Scholar
• Guilhen C, Forestier C, Balestrino D. 2017. Biofilm dispersal: multiple elaborate strategies for dissemination of bacteria with unique properties. Mol Microbiol. 105:188–210. doi:10.1111/mmi.13698
   PubMed Web of Science ®Google Scholar
• Gunputh UF, Le H, Besinis A, Tredwin C, Handy RD. 2019. Multilayered composite coatings of titanium dioxide nanotubes decorated with zinc oxide and hydroxyapatite nanoparticles: controlled release of Zn and antimicrobial properties against Staphylococcus aureus. Int J Nanomed. 14:3583–3600. doi:10.2147/IJN.S199219
   PubMed Web of Science ®Google Scholar
• Gupta P, Sarkar S, Das B, Bhattacharjee S, Tribedi P. 2016. Biofilm, pathogenesis and prevention-a journey to break the wall: a review. Arch Microbiol. 198:1–15. doi:10.1007/s00203-015-1148-6
   PubMed Web of Science ®Google Scholar
• Gursel I, Korkusuz F, Türesin F, Alaeddinoglu NG, Hasirci V. 2001. In vivo application of biodegradable controlled antibiotic release systems for the treatment of implant-related osteomyelitis. Biomaterials. 22:73–80. doi:10.1016/s0142-9612(00)00170-8
   PubMed Web of Science ®Google Scholar
• Hadeer IM. 2016. An overview of orthopedic implants. Mathews J Orthop. 1:003.
   Google Scholar
• Hajipour MJ, Fromm KM, Ashkarran AA, Jimenez de Aberasturi D, de Larramendi IR, Rojo T, Serpooshan V, Parak WJ, Mahmoudi M. 2012. Antibacterial properties of nanoparticles. Trends Biotechnol. 30:499–511. doi:10.1016/j.tibtech.2012.06.004
   PubMed Web of Science ®Google Scholar
• Hammer ND, Skaar EP. 2011. Molecular mechanisms of Staphylococcus aureus iron acquisition. Annu Rev Microbiol. 65:129–147. doi:10.1146/annurev-micro-090110-102851
   PubMed Web of Science ®Google Scholar
• Han G, Martinez LR, Mihu MR, Friedman AJ, Friedman JM, Nosanchuk JD. 2009. Nitric oxide releasing nanoparticles are therapeutic for Staphylococcus aureus abscesses in a murine model of infection. PLoS One. 4:e7804. doi:10.1371/journal.pone.0007804
   PubMed Web of Science ®Google Scholar
• Hancock RE, Sahl HG. 2006. Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nat Biotechnol. 24:1551–1557. doi:10.1038/nbt1267
   PubMed Web of Science ®Google Scholar
• Hanssen AD. 2005. Local antibiotic delivery vehicles in the treatment of musculoskeletal infection. Clin Orthop Relat Res. 91–96.
   PubMed Web of Science ®Google Scholar
• Harms A, Maisonneuve E, Gerdes K. 2016. Mechanisms of bacterial persistence during stress and antibiotic exposure. Science. 354:aaf4268. doi:10.1126/science.aaf4268
   PubMed Web of Science ®Google Scholar
• Harper D, Parracho H, Walker J, Sharp R, Hughes G, Werthén M, Lehman S, Morales S. 2014. Bacteriophages and Biofilms. Antibiotics (Basel). 3:270–284. doi:10.3390/antibiotics3030270
   Google Scholar
• Hauser J, Esenwein SA, Awakowicz P, Steinau HU, Köller M, Halfmann H. 2011. Sterilization of heat-sensitive silicone implant material by low-pressure gas plasma. Biomed Instrum Technol. 45:75–79. doi:10.2345/0899-8205-45.1.75
   PubMedGoogle Scholar
• Hazer DB, Sakar M, Dere Y, Altinkanat G, Ziyal MI, Hazer B. 2016. Antimicrobial effect of polymer-based silver nanoparticle coated pedicle screws: experimental research on biofilm inhibition in rabbits. Spine (Phila Pa 1976)). 41:E323–E329. doi:10.1097/BRS.0000000000001223
   PubMed Web of Science ®Google Scholar
• Heilmann C, Schweitzer O, Gerke C, Vanittanakom N, Mack D, Götz F. 1996. Molecular basis of intercellular adhesion in the biofilm-forming Staphylococcus epidermidis. Mol Microbiol. 20:1083–1091. doi:10.1111/j.1365-2958.1996.tb02548.x
   PubMed Web of Science ®Google Scholar
• Heimann RB. 2016. Plasma-sprayed hydroxylapatite-based coatings: chemical, mechanical, microstructural, and biomedical properties. J Therm Spray Tech. 25:827–850. doi:10.1007/s11666-016-0421-9
   Web of Science ®Google Scholar
• Henein A. 2013. What are the limitations on the wider therapeutic use of phage? Bacteriophage. 3:e24872. doi:10.4161/bact.24872
   PubMedGoogle Scholar
• Hentzer M, Wu H, Andersen JB, Riedel K, Rasmussen TB, Bagge N, Kumar N, Schembri MA, Song Z, Kristoffersen P, et al. 2003. Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. Embo J. 22:3803–3815. doi:10.1093/emboj/cdg366
   PubMed Web of Science ®Google Scholar
• Hetrick EM, Schoenfisch MH. 2006. Reducing implant-related infections: active release strategies. Chem Soc Rev. 35:780–789. doi:10.1039/b515219b
   PubMed Web of Science ®Google Scholar
• Hetrick EM, Shin JH, Stasko NA, Johnson CB, Wespe DA, Holmuhamedov E, Schoenfisch MH. 2008. Bactericidal efficacy of nitric oxide-releasing silica nanoparticles. Acs Nano. 2:235–246. doi:10.1021/nn700191f
   PubMed Web of Science ®Google Scholar
• Hickok NJ, Shapiro IM. 2012. Immobilized antibiotics to prevent orthopaedic implant infections. Adv Drug Deliv Rev. 64:1165–1176. doi:10.1016/j.addr.2012.03.015
   PubMed Web of Science ®Google Scholar
• Horsley H, Owen J, Browning R, Carugo D, Malone-Lee J, Stride E, Rohn JL. 2019. Ultrasound-activated microbubbles as a novel intracellular drug delivery system for urinary tract infection. J Control Release. 301:166–175. doi:10.1016/j.jconrel.2019.03.017
   PubMed Web of Science ®Google Scholar
• Hoyos-Nogués M, Buxadera-Palomero J, Ginebra MP, Manero JM, Gil FJ, Mas-Moruno C. 2018. All-in-one trifunctional strategy: a cell adhesive, bacteriostatic and bactericidal coating for titanium implants. Colloids Surf B Biointerfaces. 169:30–40. doi:10.1016/j.colsurfb.2018.04.050
   PubMed Web of Science ®Google Scholar
• Hu J, Zhang N, Li L, Zhang N, Ma Y, Zhao C, Wu Q, Li Y, He N, Wang X. 2018. The synergistic bactericidal effect of vancomycin on UTMD treated biofilm involves damage to bacterial cells and enhancement of metabolic activities. Sci Rep. 8:192. doi:10.1038/s41598-017-18496-3
   PubMed Web of Science ®Google Scholar
• Hui WL, Perrotti V, Iaculli F, Piattelli A, Quaranta A. 2020. The emerging role of cold atmospheric plasma in implantology: a review of the literature. Nanomaterials. 10:1505. doi:10.3390/nano10081505
   Web of Science ®Google Scholar
• Hur YE, Park Y. 2016. Vancomycin-functionalized gold and silver nanoparticles as an antibacterial nanoplatform against methicillin-resistant Staphylococcus aureus. J Nanosci Nanotechnol. 16:6393–6399. doi:10.1166/jnn.2016.12393
   PubMed Web of Science ®Google Scholar
• Inzana JA, Trombetta RP, Schwarz EM, Kates SL, Awad HA. 2015. 3D printed bioceramics for dual antibiotic delivery to treat implant-associated bone infection. Eur Cell Mater. 30:232–247. doi:10.22203/ecm.v030a16
   PubMed Web of Science ®Google Scholar
• Iram NE, Khan MS, Jolly R, Arshad M, Alam M, Alam P, Khan RH, Firdaus F. 2015. Interaction mode of polycarbazole-titanium dioxide nanocomposite with DNA: molecular docking simulation and in-vitro antimicrobial study. J Photochem Photobiol B. 153:20–32. doi:10.1016/j.jphotobiol.2015.09.001
   PubMed Web of Science ®Google Scholar
• Jiang Q, Chen J, Yang C, Yin Y, Yao K. 2019. Quorum sensing: a prospective therapeutic target for bacterial diseases. Biomed Res Int. 2019:2015978. doi:10.1155/2019/2015978
   PubMed Web of Science ®Google Scholar
• Jiranek WA, Hanssen AD, Greenwald AS. 2006. Antibiotic-loaded bone cement for infection prophylaxis in total joint replacement. J Bone Joint Surg Am. 88:2487–2500. doi:10.2106/JBJS.E.01126
   PubMed Web of Science ®Google Scholar
• Joo HS, Fu CI, Otto M. 2016. Bacterial strategies of resistance to antimicrobial peptides. Phil Trans R Soc B. 371:20150292. doi:10.1098/rstb.2015.0292
   PubMed Web of Science ®Google Scholar
• Joosten U, Joist A, Gosheger G, Liljenqvist U, Brandt B, von Eiff C. 2005. Effectiveness of hydroxyapatite-vancomycin bone cement in the treatment of Staphylococcus aureus induced chronic osteomyelitis. Biomaterials. 26:5251–5258. doi:10.1016/j.biomaterials.2005.01.001
   PubMed Web of Science ®Google Scholar
• Jose B, Antoci V, Jr, Zeiger AR, Wickstrom E, Hickok NJ. 2005. Vancomycin covalently bonded to titanium beads kills Staphylococcus aureus. Chem Biol. 12:1041–1048. doi:10.1016/j.chembiol.2005.06.013
   PubMed Web of Science ®Google Scholar
• Josse J, Valour F, Maali Y, Diot A, Batailler C, Ferry T, Laurent F. 2019. Interaction between staphylococcal biofilm and bone: how does the presence of biofilm promote prosthesis loosening? Front Microbiol. 10:1602. doi:10.3389/fmicb.2019.01602
   PubMed Web of Science ®Google Scholar
• Kahl BC, Becker K, Loffler B. 2016. Clinical significance and pathogenesis of staphylococcal small colony variants in persistent infections. Clin Microbiol Rev. 29:401–427. doi:10.1128/CMR.00069-15
   PubMed Web of Science ®Google Scholar
• Kahl BC, Becker K, Löffler B. 2016. Clinical significance and pathogenesis of staphylococcal small colony variants in persistent infections. Clin Microbiol Rev. 29:401–427. doi:10.1128/CMR.00069-15
   PubMed Web of Science ®Google Scholar
• Kalia VC, Wood TK, Kumar P. 2014. Evolution of resistance to quorum-sensing inhibitors. Microb Ecol. 68:13–23. doi:10.1007/s00248-013-0316-y
   PubMed Web of Science ®Google Scholar
• Kang J, Dietz MJ, Li B. 2019. Antimicrobial peptide LL-37 is bactericidal against Staphylococcus aureus biofilms. PLoS One. 14:e0216676. doi:10.1371/journal.pone.0216676
   PubMed Web of Science ®Google Scholar
• Kang SJ, Park SJ, Mishig-Ochir T, Lee BJ. 2014. Antimicrobial peptides: therapeutic potentials. Expert Rev Anti Infect Ther. 12:1477–1486. doi:10.1586/14787210.2014.976613
   PubMed Web of Science ®Google Scholar
• Kantlehner M, Schaffner P, Finsinger D, Meyer J, Jonczyk A, Diefenbach B, Nies B, Hölzemann G, Goodman SL, Kessler H. 2000. Surface coating with cyclic RGD peptides stimulates osteoblast adhesion and proliferation as well as bone formation. Chembio Chem. 1:107–114. doi:10.1002/1439-7633(20000818)1:2<107::AID-CBIC107>3.0.CO;2-4
   PubMed Web of Science ®Google Scholar
• Kaplan JB. 2009. Therapeutic potential of biofilm-dispersing enzymes. Int J Artif Organs. 32:545–554. doi:10.1177/039139880903200903
   PubMed Web of Science ®Google Scholar
• Karaman O, Kelebek S, Demirci EA, İbiş F, Ulu M, Ercan UK. 2018. Synergistic effect of cold plasma treatment and RGD peptide coating on cell proliferation over titanium surfaces. Tissue Eng Regen Med. 15:13–24. doi:10.1007/s13770-017-0087-5
   PubMed Web of Science ®Google Scholar
• Kasithevar M, Periakaruppan P, Muthupandian S, Mohan M. 2017. Antibacterial efficacy of silver nanoparticles against multi-drug resistant clinical isolates from post-surgical wound infections. Microb Pathog. 107:327–334. doi:10.1016/j.micpath.2017.04.013
   PubMed Web of Science ®Google Scholar
• Kaur S, Harjai K, Chhibber S. 2014. Bacteriophage-aided intracellular killing of engulfed methicillin-resistant Staphylococcus aureus (MRSA) by murine macrophages. Appl Microbiol Biotechnol. 98:4653–4661. doi:10.1007/s00253-014-5643-5
   PubMed Web of Science ®Google Scholar
• Kaur S, Harjai K, Chhibber S. 2014. Local delivery of linezolid from poly-D,L-lactide (PDLLA)-linezolid-coated orthopaedic implants to prevent MRSA mediated post-arthroplasty infections. Diagn Microbiol Infect Dis. 79:387–392. doi:10.1016/j.diagmicrobio.2014.01.026
   PubMed Web of Science ®Google Scholar
• Kaur S, Harjai K, Chhibber S. 2016. In vivo assessment of phage and linezolid based implant coatings for treatment of methicillin resistant S. aureus (MRSA) mediated orthopaedic device related infections. PLoS One. 11:e0157626. doi:10.1371/journal.pone.0157626
   PubMed Web of Science ®Google Scholar
• Kazemzadeh-Narbat M, Noordin S, Masri BA, Garbuz DS, Duncan CP, Hancock REW, Wang R. 2012. Drug release and bone growth studies of antimicrobial peptide-loaded calcium phosphate coating on titanium. J Biomed Mater Res B Appl Biomater. 100:1344–1352. doi:10.1002/jbm.b.32701
   PubMed Web of Science ®Google Scholar
• Keum H, Kim JY, Yu B, Yu SJ, Kim J, Jeon H, Lee DY, Im SG, Jon S. 2017. Prevention of bacterial colonization on catheters by a one-step coating process involving an Antibiofouling Polymer in Water . ACS Appl Mater Interfaces. 9:19736–19745. doi:10.1021/acsami.7b06899
   PubMed Web of Science ®Google Scholar
• Khalaf H, Hussien B, Alzubaidi T. 2018. Anti-bacterial evaluation of biocomposite coated dental implant after immersion in glycopeptide. Indian J Nat Sci. 8:49.
   Google Scholar
• Khalifa L, Brosh Y, Gelman D, Coppenhagen-Glazer S, Beyth S, Poradosu-Cohen R, Que Y-A, Beyth N, Hazan R. 2015. Targeting Enterococcus faecalis biofilms with phage therapy. Appl Environ Microbiol. 81:2696–2705. doi:10.1128/AEM.00096-15
   PubMed Web of Science ®Google Scholar
• Khan F, Manivasagan P, Lee JW, Pham DTN, Oh J, Kim YM. 2019. Fucoidan-stabilized gold nanoparticle-mediated biofilm inhibition, attenuation of virulence and motility properties in Pseudomonas aeruginosa PAO1. Mar Drugs. 17:208. doi:10.3390/md17040208
   PubMed Web of Science ®Google Scholar
• Khatoon Z, McTiernan CD, Suuronen EJ, Mah TF, Alarcon EI. 2018. Bacterial biofilm formation on implantable devices and approaches to its treatment and prevention. Heliyon. 4:e01067. doi:10.1016/j.heliyon.2018.e01067
   PubMed Web of Science ®Google Scholar
• Kim MK, Zhao A, Wang A, Brown ZZ, Muir TW, Stone HA, Bassler BL. 2017. Surface-attached molecules control Staphylococcus aureus quorum sensing and biofilm development. Nat Microbiol. 2:17080. doi:10.1038/nmicrobiol.2017.80
   PubMed Web of Science ®Google Scholar
• Kishor C, Mishra RR, Saraf SK, Kumar M, Srivastav AK, Nath G. 2016. Phage therapy of staphylococcal chronic osteomyelitis in experimental animal model. Indian J Med Res. 143:87–94. doi:10.4103/0971-5916.178615
   PubMed Web of Science ®Google Scholar
• Kose N, Çaylak R, Pekşen C, Kiremitçi A, Burukoglu D, Koparal S, Doğan A. 2016. Silver ion doped ceramic nano-powder coated nails prevent infection in open fractures: In vivo study. Injury. 47:320–324. doi:10.1016/j.injury.2015.10.006
   PubMed Web of Science ®Google Scholar
• Krzyżek P. 2019. Challenges and limitations of anti-quorum sensing therapies. Front Microbiol. 10:2473. doi:10.3389/fmicb.2019.02473
   PubMed Web of Science ®Google Scholar
• Kubica M, Guzik K, Koziel J, Zarebski M, Richter W, Gajkowska B, Golda A, Maciag-Gudowska A, Brix K, Shaw L, et al. 2008. A potential new pathway for Staphylococcus aureus dissemination: the silent survival of S. aureus phagocytosed by human monocyte-derived macrophages. PLoS One. 3:e1409. doi:10.1371/journal.pone.0001409
   PubMed Web of Science ®Google Scholar
• Kumar A, Alam A, Rani M, Ehtesham NZ, Hasnain SE. 2017. Biofilms: survival and defense strategy for pathogens. Int J Med Microbiol. 307:481–489. doi:10.1016/j.ijmm.2017.09.016
   PubMed Web of Science ®Google Scholar
• Kuo D, Yu G, Hoch W, Gabay D, Long L, Ghannoum M, Nagy N, Harding CV, Viswanathan R, Shoham M. 2015. Novel quorum-quenching agents promote methicillin-resistant Staphylococcus aureus (MRSA) wound healing and sensitize MRSA to β-lactam antibiotics. Antimicrob Agents Chemother. 59:1512–1518. doi:10.1128/AAC.04767-14
   PubMed Web of Science ®Google Scholar
• Kuper M, Rosenstein A. 2008. Infection prevention in total knee and total hip arthroplasties. Am J Orthop (Belle Mead NJ)). 37:E2–E5.
   PubMedGoogle Scholar
• Kurtz SM, Lau E, Schmier J, Ong KL, Zhao K, Parvizi J. 2008. Infection burden for hip and knee arthroplasty in the United States. J Arthroplasty. 23:984–991. doi:10.1016/j.arth.2007.10.017
   PubMed Web of Science ®Google Scholar
• Kurtz SM, Lau E, Watson H, Schmier JK, Parvizi J. 2012. Economic burden of periprosthetic joint infection in the United States. J Arthroplasty. 27:61–65.e1. doi:10.1016/j.arth.2012.02.022
   PubMed Web of Science ®Google Scholar
• Kutateladze M, Adamia R. 2010. Bacteriophages as potential new therapeutics to replace or supplement antibiotics. Trends Biotechnol. 28:591–595. doi:10.1016/j.tibtech.2010.08.001
   PubMed Web of Science ®Google Scholar
• Lade H, Paul D, Kweon JH. 2014. Quorum quenching mediated approaches for control of membrane biofouling. Int J Biol Sci. 10:550–565. doi:10.7150/ijbs.9028
   PubMed Web of Science ®Google Scholar
• LaSarre B, Federle MJ. 2013. Exploiting quorum sensing to confuse bacterial pathogens. Microbiol Mol Biol Rev. 77:73–111. doi:10.1128/MMBR.00046-12
   PubMed Web of Science ®Google Scholar
• Latka A, Maciejewska B, Majkowska-Skrobek G, Briers Y, Drulis-Kawa Z. 2017. Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process. Appl Microbiol Biotechnol. 101:3103–3119. doi:10.1007/s00253-017-8224-6
   PubMed Web of Science ®Google Scholar
• Lattwein KR, Shekhar H, Kouijzer JJP, van Wamel WJB, Holland CK, Kooiman K. 2020. Sonobactericide: an emerging treatment strategy for bacterial infections. Ultrasound Med Biol. 46:193–215. doi:10.1016/j.ultrasmedbio.2019.09.011
   PubMed Web of Science ®Google Scholar
• Lawson MC, Hoth KC, Deforest CA, Bowman CN, Anseth KS. 2010. Inhibition of Staphylococcus epidermidis biofilms using polymerizable vancomycin derivatives. Clin Orthop Relat Res. 468:2081–2091. doi:10.1007/s11999-010-1266-z
   PubMed Web of Science ®Google Scholar
• Lee J, Zhang L. 2015. The hierarchy quorum sensing network in Pseudomonas aeruginosa. Protein Cell. 6:26–41. doi:10.1007/s13238-014-0100-x
   PubMed Web of Science ®Google Scholar
• Lemire JA, Kalan L, Bradu A, Turner RJ. 2015. Silver oxynitrate, an unexplored silver compound with antimicrobial and antibiofilm activity. Antimicrob Agents Chemother. 59:4031–4039. doi:10.1128/AAC.05177-14
   PubMed Web of Science ®Google Scholar
• Lentino JR. 2003. Prosthetic joint infections: bane of orthopedists, challenge for infectious disease specialists. Clin Infect Dis. 36:1157–1161. doi:10.1086/374554
   PubMed Web of Science ®Google Scholar
• Lesniak A, Salvati A, Santos-Martinez MJ, Radomski MW, Dawson KA, Aberg C. 2013. Nanoparticle adhesion to the cell membrane and its effect on nano-particle uptake efficiency. J Am Chem Soc. 135:1438–1444. doi:10.1021/ja309812z
   PubMed Web of Science ®Google Scholar
• Leuba KD, Durmus NG, Taylor EN, Webster TJ. 2013. Short communication: Carboxylate functionalized super paramagnetic iron oxide nanoparticles (SPION) for the reduction of S. aureus growth post biofilm formation. Int J Nanomed. 8:731–736.
   PubMed Web of Science ®Google Scholar
• Lewies A, Du Plessis LH, Wentzel JF. 2019. Antimicrobial peptides: the achilles' heel of antibiotic resistance? Probiotics Antimicrob Prot. 11:370–381. doi:10.1007/s12602-018-9465-0
   PubMed Web of Science ®Google Scholar
• Lewies A, Du Plessis LH, Wentzel JF. 2019. Antimicrobial peptides: the achilles' heel of antibiotic resistance? Probiotics Antimicrob Prot. 11:370–381. doi:10.1007/s12602-018-9465-0
   PubMed Web of Science ®Google Scholar
• Li X, Contreras-Garcia A, LoVetri K, Yakandawala N, Wertheimer MR, De Crescenzo G, Hoemann CD. 2015. Fusion peptide P15-CSP shows antibiofilm activity and pro-osteogenic activity when deposited as a coating on hydrophilic but not hydrophobic surfaces. J Biomed Mater Res A. 103:3736–3746. doi:10.1002/jbm.a.35511
   PubMed Web of Science ®Google Scholar
• Li Y, Huang J, Li L, Liu L. 2017. Synergistic activity of berberine with azithromycin against Pseudomonas aeruginosa isolated from patients with cystic fibrosis of lung in vitro and in vivo. Cell Physiol Biochem. 42:1657–1669. doi:10.1159/000479411
   PubMedGoogle Scholar
• Li Y, Song Y, Ma A, Li C. 2019. Surface immobilization of TiO2 nanotubes with bone morphogenetic protein-2 synergistically enhances initial preosteoblast adhesion and osseointegration. Biomed Res Int. 2019:5697250. doi:10.1155/2019/5697250
   PubMed Web of Science ®Google Scholar
• Lister JL, Horswill AR. 2014. Staphylococcus aureus biofilms: recent developments in biofilm dispersal. Front Cell Infect Microbiol. 4:178. doi:10.3389/fcimb.2014.00178
   PubMed Web of Science ®Google Scholar
• Lister JL, Horswill AR. 2014. Staphylococcus aureus biofilms: recent developments in biofilm dispersal. Front Cell Infect Microbiol. 4:178. doi:10.3389/fcimb.2014.00178
   PubMed Web of Science ®Google Scholar
• Liu L, Bhatia R, Webster TJ. 2017. Atomic layer deposition of nano-TiO2 thin films with enhanced biocompatibility and antimicrobial activity for orthopedic implants. Int J Nanomed. 12:8711–8723. doi:10.2147/IJN.S148065
   PubMed Web of Science ®Google Scholar
• Liu Z, Ma S, Duan S, Xuliang D, Sun Y, Zhang X, Xu X, Guan B, Wang C, Hu M, et al. 2016. Modification of titanium substrates with chimeric peptides comprising antimicrobial and titanium-binding motifs connected by linkers to inhibit biofilm formation. ACS Appl Mater Interfaces. 8:5124–5136. doi:10.1021/acsami.5b11949
   PubMed Web of Science ®Google Scholar
• Los A, Ziuzina D, Boehm D, Han L, O'Sullivan D, O'Neill L, Bourke P. 2019. Efficacy of cold plasma for direct deposition of antibiotics as a novel approach for localized delivery and retention of effect. Front Cell Infect Microbiol. 9:428. doi:10.3389/fcimb.2019.00428
   PubMed Web of Science ®Google Scholar
• Lu TK, Collins JJ. 2007. Dispersing biofilms with engineered enzymatic bacteriophage. Proc Natl Acad Sci USA. 104:11197–11202. doi:10.1073/pnas.0704624104
   PubMed Web of Science ®Google Scholar
• Lucke M, Schmidmaier G, Sadoni S, Wildemann B, Schiller R, Haas NP, Raschke M. 2003. Gentamicin coating of metallic implants reduces implant-related osteomyelitis in rats. Bone. 32:521–531. doi:10.1016/s8756-3282(03)00050-4
   PubMed Web of Science ®Google Scholar
• Luo J, Dong B, Wang K, Cai S, Liu T, Cheng X, Lei D, Chen Y, Li Y, Kong J, et al. 2017. Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal implant infection model. PLoS One. 12:e0176883. doi:10.1371/journal.pone.0176883
   PubMed Web of Science ®Google Scholar
• LuTheryn G, Glynne-Jones P, Webb JS, Carugo D. 2020. Ultrasound-mediated therapies for the treatment of biofilms in chronic wounds: a review of present knowledge. Microb Biotechnol. 13:613–628. doi:10.1111/1751-7915.13471
   PubMed Web of Science ®Google Scholar
• Ma M, Kazemzadeh-Narbat M, Hui Y, Lu S, Ding C, Chen DDY, Hancock REW, Wang R. 2012. Local delivery of antimicrobial peptides using self-organized TiO2 nanotube arrays for peri-implant infections. J Biomed Mater Res A. 100:278–285. doi:10.1002/jbm.a.33251
   PubMed Web of Science ®Google Scholar
• Maciejewska B, Olszak T, Drulis-Kawa Z. 2018. Applications of bacteriophages versus phage enzymes to combat and cure bacterial infections: an ambitious and also a realistic application? Appl Microbiol Biotechnol. 102:2563–2581. doi:10.1007/s00253-018-8811-1
   PubMed Web of Science ®Google Scholar
• Magyari K, Nagy-Simon T, Vulpoi A, Popescu RA, Licarete E, Stefan R, Hernádi K, Papuc I, Baia L. 2017. Novel bioactive glass-AuNP composites for biomedical applications. Mater Sci Eng C Mater Biol Appl. 76:752–759. doi:10.1016/j.msec.2017.03.138
   PubMed Web of Science ®Google Scholar
• Mah TF, O'Toole GA. 2001. Mechanisms of biofilm resistance to antimicrobial agents. Trends Microbiol. 9:34–39. doi:10.1016/S0966-842X(00)01913-2
   PubMed Web of Science ®Google Scholar
• Malik DJ, Sokolov IJ, Vinner GK, Mancuso F, Cinquerrui S, Vladisavljevic GT, Clokie MRJ, Garton NJ, Stapley AGF, Kirpichnikova A. 2017. Formulation, stabilisation and encapsulation of bacteriophage for phage therapy. Adv Colloid Interface Sci. 249:100–133. doi:10.1016/j.cis.2017.05.014
   PubMed Web of Science ®Google Scholar
• Mangano F, Chambrone L, van Noort R, Miller C, Hatton P, Mangano C. 2014. Direct metal laser sintering titanium dental implants: a review of the current literature. Int J Biomater. 2014:461534. doi:10.1155/2014/461534
   PubMedGoogle Scholar
• Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR. 1999. Guideline for prevention of surgical site infection. Centers for Disease Control and Prevention Hospital Infection Control Practices Advisory Committee. Am J Infect Control. 27:97–132.
   PubMed Web of Science ®Google Scholar
• Mansour SC, de la Fuente-Núñez C, Hancock RE. 2015. Peptide IDR-1018: modulating the immune system and targeting bacterial biofilms to treat antibiotic-resistant bacterial infections. J Pept Sci. 21:323–329. doi:10.1002/psc.2708
   PubMed Web of Science ®Google Scholar
• Mansour SC, Pena OM, Hancock RE. 2014. Host defense peptides: front-line immunomodulators. Trends Immunol. 35:443–450. doi:10.1016/j.it.2014.07.004
   PubMed Web of Science ®Google Scholar
• Markowska K, Grudniak AM, Wolska KI. 2013. Silver nanoparticles as an alternative strategy against bacterial biofilms. Acta Biochim Pol. 60:523–530.
   PubMed Web of Science ®Google Scholar
• Martínez LC, Vadyvaloo V. 2014. Mechanisms of post-transcriptional gene regulation in bacterial biofilms. Front Cell Infect Microbiol. 4:38. doi:10.3389/fcimb.2014.00038
   PubMed Web of Science ®Google Scholar
• Mathur P, Jha S, Ramteke S, Jain NK. 2018. Pharmaceutical aspects of silver nanoparticles. Artif Cells Nanomed Biotechnol. 46:115–126. doi:10.1080/21691401.2017.1414825
   PubMed Web of Science ®Google Scholar
• Matsuzaki S, Yasuda M, Nishikawa H, Kuroda M, Ujihara T, Shuin T, Shen Y, Jin Z, Fujimoto S, Nasimuzzaman MD, et al. 2003. Experimental protection of mice against lethal Staphylococcus aureus infection by novel bacteriophage phi MR11. J Infect Dis. 187:613–624. doi:10.1086/374001
   PubMed Web of Science ®Google Scholar
• McCaskie AW, Richardson JB, Gregg PJ. 1998. Further uses of polymethylmethacrylate in orthopaedic surgery. J R Coll Surg Edinb. 43:37–39.
   PubMedGoogle Scholar
• McConoughey SJ, Howlin R, Granger JF, Manring MM, Calhoun JH, Shirtliff M, Kathju S, Stoodley P. 2014. Biofilms in periprosthetic orthopedic infections. Future Microbiol. 9:987–1007. doi:10.2217/fmb.14.64
   PubMed Web of Science ®Google Scholar
• Memarzadeh K, Sharili AS, Huang J, Rawlinson SC, Allaker RP. 2015. Nanoparticulate zinc oxide as a coating material for orthopedic and dental implants. J Biomed Mater Res A. 103:981–989. doi:10.1002/jbm.a.35241
   PubMed Web of Science ®Google Scholar
• Metsemakers W-J, Morgenstern M, Senneville E, Borens O, Govaert GAM, Onsea J, Depypere M, Richards RG, Trampuz A, Verhofstad MHJ, et al. 2020. General treatment principles for fracture-related infection: recommendations from an international expert group. Arch Orthop Trauma Surg. 140:1013–1027. doi:10.1007/s00402-019-03287-4
   PubMed Web of Science ®Google Scholar
• Miola M, Fucale G, Maina G, Verné E. 2015. Antibacterial and bioactive composite bone cements containing surface silver-doped glass particles. Biomed Mater. 10:055014. doi:10.1088/1748-6041/10/5/055014
   PubMed Web of Science ®Google Scholar
• Mohamed MF, Abdelkhalek A, Seleem MN. 2016. Evaluation of short synthetic antimicrobial peptides for treatment of drug-resistant and intracellular Staphylococcus aureus. Sci Rep. 6:29707. doi:10.1038/srep29707
   PubMed Web of Science ®Google Scholar
• Mohamed W, Sommer U, Sethi S, Domann E, Thormann U, Schütz I, Lips KS, Chakraborty T, Schnettler R, Alt V, et al. 2014. Intracellular proliferation of S. aureus in osteoblasts and effects of rifampicin and gentamicin on S. aureus intracellular proliferation and survival. Eur Cell Mater. 28:258–268. doi:10.22203/ecm.v028a18
   PubMed Web of Science ®Google Scholar
• Møller IM, Jensen PE, Hansson A. 2007. Oxidative modifications to cellular components in plants. Annu Rev Plant Biol. 58:459–481. doi:10.1146/annurev.arplant.58.032806.103946
   PubMed Web of Science ®Google Scholar
• Mootz JM, Malone CL, Shaw LN, Horswill AR. 2013. Staphopains modulate Staphylococcus aureus biofilm integrity. Infect Immun. 81:3227–3238. doi:10.1128/IAI.00377-13
   PubMed Web of Science ®Google Scholar
• Mora-Boza A, Aparicio FJ, Alcaire M, López-Santos C, Espinós JP, Torres-Lagares D, Borrás A, Barranco A. 2019. Multifunctional antimicrobial chlorhexidine polymers by remote plasma assisted vacuum deposition. Front Chem Sci Eng. 13:330–339. doi:10.1007/s11705-019-1803-6
   Web of Science ®Google Scholar
• Moriarty TF, Kuehl R, Coenye T, Metsemakers W-J, Morgenstern M, Schwarz EM, Riool M, Zaat SAJ, Khana N, Kates SL, et al. 2016. Orthopaedic device-related infection: current and future interventions for improved prevention and treatment. EFORT Open Rev. 1:89–99. doi:10.1302/2058-5241.1.000037
   PubMed Web of Science ®Google Scholar
• Morris JL, Letson HL, Elliott L, Grant AL, Wilkinson M, Hazratwala K, McEwen P. 2019. Evaluation of bacteriophage as an adjunct therapy for treatment of peri-prosthetic joint infection caused by Staphylococcus aureus. PLoS One. 14:e0226574 doi:10.1371/journal.pone.0226574
   PubMed Web of Science ®Google Scholar
• Múgica-Vidal R, Sainz-García E, Álvarez-Ordóñez A, Prieto M, González-Raurich M, López M, López M, Rojo-Bezares B, Sáenz Y, Alba-Elías F, et al. 2019. Production of antibacterial coatings through atmospheric pressure plasma: a promising alternative for combatting biofilms in the food industry. Food Bioprocess Technol. 12:1251–1263. doi:10.1007/s11947-019-02293-z
   Web of Science ®Google Scholar
• Nahar S, Mizan MFR, Ha AJW, Ha SD. 2018. Advances and future prospects of enzyme-based biofilm prevention approaches in the food industry. Compr Rev Food Sci Food Saf. 17:1484–1502. doi:10.1111/1541-4337.12382
   PubMed Web of Science ®Google Scholar
• Nelson DC, Schmelcher M, Rodriguez-Rubio L, Klumpp J, Pritchard DG, Dong S, Donovan DM. 2012. Endolysins as antimicrobials. Adv Virus Res. 83:299–365. doi:10.1016/B978-0-12-394438-2.00007-4
   PubMed Web of Science ®Google Scholar
• Neupane MP, Lee SJ, Park IS, Lee MH, Bae TS, Kuboki Y, Uo M, Watari F. 2011. Synthesis of gelatin-capped gold nanoparticles with variable gelatin concentration. J Nanopart Res. 13:491–498. doi:10.1007/s11051-010-9971-9
   Web of Science ®Google Scholar
• Nijnik A, Hancock R. 2009. Host defence peptides: antimicrobial and immunomodulatory activity and potential applications for tackling antibiotic-resistant infections. Emerg Health Threats J. 2:e1 doi:10.3134/ehtj.09.001
   PubMedGoogle Scholar
• Nilsson AS. 2019. Pharmacological limitations of phage therapy. Ups J Med Sci. 124:218–227. doi:10.1080/03009734.2019.1688433
   PubMed Web of Science ®Google Scholar
• O’Connor C, Kiourti A. 2017. Wireless sensors for smart orthopedic implants. J Bio Tribo Corros. 3:20. doi:10.1007/s40735-017-0078-z
   Google Scholar
• Obremskey WT, Bhandari M, Dirschl DR, Shemitsch E. 2003. Internal fixation versus arthroplasty of comminuted fractures of the distal humerus. J Orthop Trauma. 17:463–465. doi:10.1097/00005131-200307000-00014
   PubMed Web of Science ®Google Scholar
• O'Halloran DP, Wynne K, Geoghegan JA. 2015. Protein A is released into the Staphylococcus aureus culture supernatant with an unprocessed sorting signal. Infect Immun. 83:1598–1609. doi:10.1128/IAI.03122-14
   PubMed Web of Science ®Google Scholar
• Okshevsky M, Regina VR, Meyer RL. 2015. Extracellular DNA as a target for biofilm control. Curr Opin Biotechnol. 33:73–80. doi:10.1016/j.copbio.2014.12.002
   PubMed Web of Science ®Google Scholar
• Olsen N, Thiran E, Hasler T, Vanzieleghem T, Belibasakis G, Mahillon J, Loessner M, Schmelcher M. 2018. Synergistic Removal of static and dynamic Staphylococcus aureus biofilms by combined treatment with a bacteriophage endolysin and a polysaccharide depolymerase. Viruses. 10:438. doi:10.3390/v10080438
   PubMed Web of Science ®Google Scholar
• Onsea J, Soentjens P, Djebara S, et al. 2019. Bacteriophage application for difficult-to-treat musculoskeletal infections: development of a standardized multidisciplinary treatment protocol. Viruses. 11:891. doi:10.3390/v11100891
   Web of Science ®Google Scholar
• Ooi N, Miller K, Randall C, Rhys-Williams W, Love W, Chopra I. 2010. XF-70 and XF-73, novel antibacterial agents active against slow-growing and non-dividing cultures of Staphylococcus aureus including biofilms. J Antimicrob Chemother. 65:72–78. doi:10.1093/jac/dkp409.
   PubMed Web of Science ®Google Scholar
• Otto M. 2008. Staphylococcal biofilms. Curr Top Microbiol Immunol. 322:207–228. doi:10.1007/978-3-540-75418-3_10
   PubMed Web of Science ®Google Scholar
• Otto M. 2014. Phenol-soluble modulins. Int J Med Microbiol. 304:164–169. doi:10.1016/j.ijmm.2013.11.019
   PubMed Web of Science ®Google Scholar
• Overhage J, Campisano A, Bains M, Torfs EC, Rehm BH, Hancock RE. 2008. Human host defense peptide LL-37 prevents bacterial biofilm formation. Infect Immun. 76:4176–4182. doi:10.1128/IAI.00318-08
   PubMed Web of Science ®Google Scholar
• Padmavathy N, Vijayaraghavan R. 2008. Enhanced bioactivity of ZnO nanoparticles-an antimicrobial study. Sci Technol Adv Mater. 9:035004. doi:10.1088/1468-6996/9/3/035004
   PubMed Web of Science ®Google Scholar
• Paharik AE, Horswill AR. 2016. The staphylococcal biofilm: adhesins, regulation, and host response. Microbiol Spectr. 4: 529–566. doi:10.1128/microbiolspec.VMBF-0022-2015
   Web of Science ®Google Scholar
• Pajarinen J, Jamsen E, Konttinen YT, Goodman SB. 2014.Innate immune reactions in septic and aseptic osteolysis around hip implants. J Long Term Eff Med Implant. 24(4):283–296. doi:10.1615/jlongtermeffmedimplants.2014010564
   PubMedGoogle Scholar
• Paluch E, Rewak-Soroczyńska J, Jędrusik I, Mazurkiewicz E, Jermakow K. 2020. Prevention of biofilm formation by quorum quenching. Appl Microbiol Biotechnol. 104:1871–1881. doi:10.1007/s00253-020-10349-w
   PubMed Web of Science ®Google Scholar
• Pan C, Zhou Z, Yu X. 2018. Coatings as the useful drug delivery system for the prevention of implant-related infections. J Orthop Surg Res. 13:220. doi:10.1186/s13018-018-0930-y
   PubMed Web of Science ®Google Scholar
• Papenfort K, Bassler BL. 2016. Quorum sensing signal-response systems in Gram-negative bacteria. Nat Rev Microbiol. 14:576–588. doi:10.1038/nrmicro.2016.89
   PubMed Web of Science ®Google Scholar
• Parisi TJ, Konopka JF, Bedair HS. 2017. What is the long-term economic societal effect of periprosthetic infections after THA? A Markov Analysis. Clin Orthop Relat Res. 475:1891–1900. doi:10.1007/s11999-017-5333-6
   PubMed Web of Science ®Google Scholar
• Parlet CP, Kavanaugh JS, Crosby HA, Raja HA, El-Elimat T, Todd DA, Pearce CJ, Cech NB, Oberlies NH, Horswill AR, et al. 2019. Apicidin attenuates MRSA virulence through quorum-sensing Inhibition and Enhanced Host Defense. Cell Rep. 27:187–198.e6. doi:10.1016/j.celrep.2019.03.018
   PubMed Web of Science ®Google Scholar
• Parvizi J, Ghanem E, Azzam K, Davis E, Jaberi F, Hozack W. 2008. Periprosthetic infection: are current treatment strategies adequate? Acta Orthop Belg. 74:793–800.
   PubMed Web of Science ®Google Scholar
• Patey O, McCallin S, Mazure H, Liddle M, Smithyman A, Dublanchet A. 2018. Clinical indications and compassionate use of phage therapy: personal experience and literature review with a focus on osteoarticular infections. Viruses. 11:18. doi:10.3390/v11010018
   PubMed Web of Science ®Google Scholar
• Pavlukhina SV, Kaplan JB, Xu L, Chang W, Yu X, Madhyastha S, Yakandawala N, Mentbayeva A, Khan B, Sukhishvili SA, et al. 2012. Noneluting enzymatic antibiofilm coatings . ACS Appl Mater Interfaces. 4:4708–4716. doi:10.1021/am3010847
   PubMed Web of Science ®Google Scholar
• Pavoni GL, Giannella M, Falcone M, Scorzolini L, Liberatore M, Carlesimo B, Venditti M, Serra P. 2004. Conservative medical therapy of prosthetic joint infections: retrospective analysis of an 8-year experience. Clin Microbiol Infect, 10(9):831–837. doi:10.1111/j.1469-0691.2004.00928.x
   PubMed Web of Science ®Google Scholar
• Peng H, Borg RE, Dow LP, Pruitt BL, Chen IA. 2020. Controlled phage therapy by photothermal ablation of specific bacterial species using gold nanorods targeted by chimeric phages. Proc Natl Acad Sci USA. 117:1951–1961. doi:10.1073/pnas.1913234117
   PubMed Web of Science ®Google Scholar
• Peng Z, Ni J, Zheng K, Shen Y, Wang X, He G, Jin S, Tang T. 2013. Dual effects and mechanism of TiO2 nanotube arrays in reducing bacterial colonization and enhancing C3H10T1/2 cell adhesion. Int J Nanomedicine. 8:3093–3105. doi:10.2147/IJN.S48084
   PubMed Web of Science ®Google Scholar
• Perez K, Patel R. 2015. Biofilm-like aggregation of Staphylococcus epidermidis in synovial fluid. J Infect Dis. 212:335–336. doi:10.1093/infdis/jiv096
   PubMed Web of Science ®Google Scholar
• Perez K, Patel R. 2018. Survival of Staphylococcus epidermidis in fibroblasts and osteoblasts. Infect Immun. 86:e00237–18. doi:10.1128/IAI.00237-18
   PubMed Web of Science ®Google Scholar
• Periasamy S, Chatterjee SS, Cheung GY, Otto M. 2012. Phenol-soluble modulins in staphylococci: what are they originally for? Commun Integr Biol. 5:275–277. doi:10.4161/cib.19420
   PubMedGoogle Scholar
• Pestrak MJ, Gupta TT, Dusane DH, Guzior DV, Staats A, Harro J, Horswill AR, Stoodley P. 2020. Correction: Investigation of synovial fluid induced Staphylococcus aureus aggregate development and its impact on surface attachment and biofilm formation. PLoS One. 15:e0233534. doi:10.1371/journal.pone.0231791
   PubMed Web of Science ®Google Scholar
• Petersen RC. 2014. Titanium implant osseointegration problems with alternate solutions using epoxy/carbon-fiber-reinforced composite. Metals (Basel). 24(4):549–569. doi:10.3390/met4040549
   Google Scholar
• Pfeufer NY, Hofmann-Peiker K, Mühle M, Warnke PH, Weigel MC, Kleine M. 2011. Bioactive coating of titanium surfaces with recombinant human β-defensin-2 (rHuβD2) may prevent bacterial colonization in orthopaedic surgery. J Bone Joint Surg Am. 93:840–846. doi:10.2106/JBJS.I.01738
   PubMed Web of Science ®Google Scholar
• Pires DP, Cleto S, Sillankorva S, Azeredo J, Lu TK. 2016. Genetically engineered phages: a review of advances over the last decade. Microbiol Mol Biol Rev. 80:523–543. doi:10.1128/MMBR.00069-15
   PubMed Web of Science ®Google Scholar
• Pleshko N, Grande DA, Myers KR. 2012. Nanotechnology in orthopaedics. J Am Acad Orthop Surg. 20:60–62. doi:10.5435/JAAOS-20-01-060
   PubMed Web of Science ®Google Scholar
• Pogodin S, Hasan J, Baulin VA, Webb HK, Truong VK, Phong Nguyen TH, Boshkovikj V, Fluke CJ, Watson GS, Watson JA, et al. 2013. Biophysical model of bacterial cell interactions with nanopatterned cicada wing surfaces. Biophys J. 104:835–840. doi:10.1016/j.bpj.2012.12.046
   PubMed Web of Science ®Google Scholar
• Pradhaban G, Kaliaraj GS, Vishwakarma V. 2014. Antibacterial effects of silver-zirconia composite coatings using pulsed laser deposition onto 316L SS for bio implants. Prog Biomater. 3:123–130. doi:10.1007/s40204-014-0028-5
   PubMedGoogle Scholar
• Principi N, Silvestri E, Esposito S. 2019. Advantages and limitations of bacteriophages for the treatment of bacterial infections. Front Pharmacol. 10:513. doi:10.3389/fphar.2019.00513
   PubMed Web of Science ®Google Scholar
• Proctor RA, Kriegeskorte A, Kahl BC, Becker K, Löffler B, Peters G. 2014. Staphylococcus aureus small colony variants (SCVs): a road map for the metabolic pathways involved in persistent infections. Front Cell Infect Microbiol. 4:99. doi:10.3389/fcimb.2014.00099
   PubMed Web of Science ®Google Scholar
• Qais FA, Shafiq A, Ahmad I, Husain FM, Khan RA, Hassan I. 2020. Green synthesis of silver nanoparticles using Carum copticum: assessment of its quorum sensing and biofilm inhibitory potential against gram negative bacterial pathogens. Microb Pathog. 144:104172. doi:10.1016/j.micpath.2020.104172
   PubMed Web of Science ®Google Scholar
• Qasim SN, Swann A, Ashford R. 2017. The DAIR (debridement, antibiotics and implant retention) procedure for infected total knee replacement – a literature review. SICOT J. 3:2. doi: 10.1051/sicotj/2016038.
   PubMed Web of Science ®Google Scholar
• Qin H, Cao H, Zhao Y, Zhu C, Cheng T, Wang Q, Peng X, Cheng M, Wang J, Jin G, et al. 2014. In vitro and in vivo anti-biofilm effects of silver nanoparticles immobilized on titanium . Biomaterials. 35:9114–9125. doi:10.1016/j.biomaterials.2014.07.040
   PubMed Web of Science ®Google Scholar
• Qing Y, Cheng L, Li R, Liu G, Zhang Y, Tang X, Wang J, Liu H, Qin Y. 2018. Potential antibacterial mechanism of silver nanoparticles and the optimization of orthopedic implants by advanced modification technologies. Int J Nanomed. 13:3311–3327. doi:10.2147/IJN.S165125
   PubMed Web of Science ®Google Scholar
• Rajamäki K, Nordström T, Nurmi K, Åkerman KEO, Kovanen PT, Öörni K, Eklund KK. 2013. Extracellular acidosis is a novel danger signal alerting innate immunity via the NLRP3 inflammasome. J Biol Chem. 288:13410–13419. doi:10.1074/jbc.M112.426254
   PubMed Web of Science ®Google Scholar
• Rao Y, Shang W, Yang Y, Zhou R, Rao X. 2020. Fighting mixed-species microbial biofilms with cold atmospheric Plasma. Front Microbiol. 11:1000. doi:10.3389/fmicb.2020.01000
   PubMed Web of Science ®Google Scholar
• Raulli R, McElhaney-Feser G, Hrabie JA, Cihlar RL. 2002. Antimicrobial properties of nitric oxide using diazeniumdiolates as the nitric oxide donor. Rec Res Devel Microbiol. 6:177–183.
   Google Scholar
• Rauschmann MA, Wichelhaus TA, Stirnal V, Dingeldein E, Zichner L, Schnettler R, Alt V. 2005. Nanocrystalline hydroxyapatite and calcium sulphate as biodegradable composite carrier material for local delivery of antibiotics in bone infections. Biomaterials. 26:2677–2684. doi:10.1016/j.biomaterials.2004.06.045
   PubMed Web of Science ®Google Scholar
• Recek N. 2019. Biocompatibility of plasma-treated polymeric implants. Materials (Basel). 12:240. doi:10.3390/ma12020240
   Web of Science ®Google Scholar
• Reffuveille F, de la Fuente-Núñez C, Mansour S, Hancock RE. 2014. A broad-spectrum antibiofilm peptide enhances antibiotic action against bacterial biofilms. Antimicrob Agents Chemother. 58:5363–5371. doi:10.1128/AAC.03163-14
   PubMed Web of Science ®Google Scholar
• Reffuveille F, de la Fuente-Nunez C, Mansour S, Hancock REW. 2014. A broad-spectrum antibiofilm peptide enhances antibiotic action against bacterial biofilms. Antimicrob Agents Chemother. 58: 5363–5371. doi:10.1128/AAC.03163-14.
   PubMed Web of Science ®Google Scholar
• Rémy B, Mion S, Plener L, Elias M, Chabrière E, Daudé D. 2018. Interference in bacterial quorum sensing: a biopharmaceutical perspective. Front Pharmacol. 9:203. doi:10.3389/fphar.2018.00203
   PubMed Web of Science ®Google Scholar
• Riool M, de Breij A, Drijfhout JW, Nibbering PH, Zaat SAJ. 2017. Antimicrobial peptides in biomedical device manufacturing. Front Chem. 5:63. doi:10.3389/fchem.2017.00063
   PubMed Web of Science ®Google Scholar
• Rodríguez-Rubio L, Martínez B, Donovan DM, García P, Rodríguez A. 2013. Potential of the virion-associated peptidoglycan hydrolase HydH5 and its derivative fusion proteins in milk biopreservation. PLoS One. 8:e54828. doi:10.1371/journal.pone.0054828
   PubMed Web of Science ®Google Scholar
• Roiniotis J, Dinh H, Masendycz P, Turner A, Elsegood CL, Scholz GM, Hamilton JA. 2009. Hypoxia prolongs monocyte/macrophage survival and enhanced glycolysis is associated with their maturation under aerobic conditions. J Immunol. 182:7974–7981. doi:10.4049/jimmunol.0804216
   PubMed Web of Science ®Google Scholar
• Romanò CL, Scarponi S, Gallazzi E, Romanò D, Drago L. 2015. Antibacterial coating of implants in orthopaedics and trauma: a classification proposal in an evolving panorama. J Orthop Surg Res. 10:157. doi:10.1186/s13018-015-0294-5
   PubMed Web of Science ®Google Scholar
• Roy M, Bandyopadhyay A, Bose S. 2011. Induction plasma sprayed nano hydroxyapatite coatings on titanium for orthopaedic and dental implants. Surf Coat Technol. 205:2785–2792. doi:10.1016/j.surfcoat.2010.10.042
   PubMed Web of Science ®Google Scholar
• Roy R, Tiwari M, Donelli G, Tiwari V. 2018. Strategies for combating bacterial biofilms: a focus on anti-biofilm agents and their mechanisms of action. Virulence. 9:522–554. doi:10.1080/21505594.2017.1313372
   PubMed Web of Science ®Google Scholar
• Rupel K, Zupin L, Ottaviani G, Bertani I, Martinelli V, Porrelli D, Vodret S, Vuerich R, Passos da Silva D, Bussani R, et al. 2019. Blue laser light inhibits biofilm formation in vitro and in vivo by inducing oxidative stress. NPJ Biofilms Microbiomes. 5:29. doi:10.1038/s41522-019-0102-9
   PubMed Web of Science ®Google Scholar
• Saggu SK, Jha G, Mishra PC. 2019. Enzymatic degradation of biofilm by metalloprotease from Microbacterium sp. SKS10. Front Bioeng Biotechnol. 7:192. doi:10.3389/fbioe.2019.00192
   PubMed Web of Science ®Google Scholar
• Saha B, Bhattacharya J, Mukherjee A, Ghosh AK, Santra CR, Dasgupta AK, Karmakar P. 2007. In vitro structural and functional evaluation of gold nanoparticles conjugated antibiotics. Nanoscale Res Lett. 2:614–622. doi:10.1007/s11671-007-9104-2
   Web of Science ®Google Scholar
• Sardella E, Palumbo F, Camporeale G, Favia P. 2016. Non-equilibrium plasma processing for the preparation of antibacterial surfaces. Materials (Basel). 9:515. doi:10.3390/ma9070515
   Web of Science ®Google Scholar
• Schaeffer CR, Woods KM, Longo GM, Kiedrowski MR, Paharik AE, Büttner H, Christner M, Boissy RJ, Horswill AR, Rohde H, et al. 2015. Accumulation-associated protein enhances Staphylococcus epidermidis biofilm formation under dynamic conditions and is required for infection in a rat catheter model. Infect Immun. 83:214–226. doi:10.1128/IAI.02177-14
   PubMed Web of Science ®Google Scholar
• Scheper H, Verhagen J, deVisser A, van der Wal R, Wubbolts J, Visser LG, Boer MGJD, Nibbering PH. 2019. Antimicrobial peptides eradicate bacteria, including persisters, in antibiotic-treated mature biofilms. In: Orthopaedic Proceedings. 101-B:
   Google Scholar
• Schmidmaier G, Lucke M, Wildemann B, Haas NP, Raschke M. 2006. Prophylaxis and treatment of implant-related infections by antibiotic-coated implants: a review. Injury. 37: S105–S112. doi:10.1016/j.injury.2006.04.016
   PubMed Web of Science ®Google Scholar
• Sebastian S, Malhotra R, Dhawan B. 2018. Prosthetic joint infection: a major threat to successful total joint arthroplasty. Indian J Med Microbiol. 36:475–487. doi:10.4103/ijmm.IJMM_19_11
   PubMed Web of Science ®Google Scholar
• Sendi P, Rohrbach M, Graber P, Frei R, Ochsner PE, Zimmerli W. 2006. Staphylococcus aureus small colony variants in prosthetic joint infection. Clin Infect Dis. 43:961–967. doi:10.1086/507633
   PubMed Web of Science ®Google Scholar
• Sendi P, Zimmerli W. 2012. Antimicrobial treatment concepts for orthopaedic device-related infection. Clin Microbiol Infect.18(12):1176–1184. doi:10.1111/1469-0691.12003
   PubMed Web of Science ®Google Scholar
• Shakiba A, Zenasni O, Marquez MD, Randall Lee T. 2017. Advanced drug delivery via self-assembled monolayer-coated nanoparticles. AIMS Bioeng. 4:275–299. doi:10.3934/bioeng.2017.2.275
   Web of Science ®Google Scholar
• Shakibaie M, Forootanfar H, Golkari Y, Mohammadi-Khorsand T, Shakibaie MR. 2015. Anti-biofilm activity of biogenic selenium nanoparticles and selenium dioxide against clinical isolates of Staphylococcus aureus, Pseudomonas aeruginosa, and Proteus mirabilis. J Trace Elem Med Biol. 29:235–241. doi:10.1016/j.jtemb.2014.07.020
   PubMed Web of Science ®Google Scholar
• Shaw P, Kumar N, Kwak HS, Park JH, Uhm HS, Bogaerts A, Choi EH, Attri P. 2018. Bacterial inactivation by plasma treated water enhanced by reactive nitrogen species. Sci Rep. 8:11268. doi:10.1038/s41598-018-29549-6
   PubMed Web of Science ®Google Scholar
• Shimazaki T, Miyamoto H, Ando Y, Noda I, Yonekura Y, Kawano S, Miyazaki M, Mawatari M, Hotokebuchi T. 2009. In vivo antibacterial and silver-releasing properties of novel thermal sprayed silver-containing hydroxyapatite coating. J Biomed Mater Res. 9999B:NA–389. doi:10.1002/jbm.b.31526
   Google Scholar
• Shirai T, Tsuchiya H, Terauchi R, Tsuchida S, Mizoshiri N, Mori Y, Takeuchi A, Hayashi K, Yamamoto N, Ikoma K, et al. 2019. A retrospective study of antibacterial iodine-coated implants for postoperative infection. Medicine (Baltimore)). 98:e17932. doi:10.1097/MD.0000000000017932
   PubMed Web of Science ®Google Scholar
• Silva RR, Avelino KY, Ribeiro KL, Franco OL, Oliveira MD, Andrade CA. 2016. Chemical immobilization of antimicrobial peptides on biomaterial surfaces. Front Biosci (Schol Ed)). 8:129–142. doi:10.2741/s453
   PubMedGoogle Scholar
• Simonetti O, Cirioni O, Cacciatore I, Baldassarre L, Orlando F, Pierpaoli E, Lucarini G, Orsetti E, Provinciali M, Fornasari E, et al. 2016. Efficacy of the quorum sensing inhibitor FS10 alone and in combination with tigecycline in an animal model of staphylococcal infected wound. PLoS One. 11:e0151956. doi:10.1371/journal.pone.0151956
   PubMed Web of Science ®Google Scholar
• Singh P, Pandit S, Mokkapati VRSS, Garg A, Ravikumar V, Mijakovic I. 2018. Gold nanoparticles in diagnostics and therapeutics for human cancer. Int J Mol Sci. 19:1979. doi:10.3390/ijms19071979
   PubMed Web of Science ®Google Scholar
• Singla S, Harjai K, Katare OP, Chhibber S. 2016. Encapsulation of bacteriophage in liposome accentuates its entry in to macrophage and shields it from neutralizing antibodies. PLoS One. 11:e0153777. doi:10.1371/journal.pone.0153777
   PubMed Web of Science ®Google Scholar
• Slavin YN, Asnis J, Häfeli UO, Bach H. 2017. Metal nanoparticles: understanding the mechanisms behind antibacterial activity. J Nanobiotechnology. 15:65. doi:10.1186/s12951-017-0308-z
   PubMed Web of Science ®Google Scholar
• Smith WR, Hudson PW, Ponce BA, Rajaram Manoharan SR. 2018. Nanotechnology in orthopedics: a clinically oriented review. BMC Musculoskelet Disord. 19:67. doi:10.1186/s12891-018-1990-1
   PubMed Web of Science ®Google Scholar
• Smyth AR, Cifelli PM, Ortori CA, Righetti K, Lewis S, Erskine P, Holland ED, Givskov M, Williams P, Cámara M, Barrett DA, et al. 2010. Garlic as an inhibitor of Pseudomonas aeruginosa quorum sensing in cystic fibrosis-a pilot randomized controlled trial. Pediatr Pulmonol. 45:356–362. doi:10.1002/ppul.21193
   PubMed Web of Science ®Google Scholar
• Spangehl MJ, Masri BA, O'Connell JX, Duncan CP. 1999. Prospective analysis of preoperative and intraoperative investigations for the diagnosis of infection at the sites of two hundred and two revision total hip arthroplasties. J Bone Joint Surg Am. 81:672–683.
   PubMed Web of Science ®Google Scholar
• Stigter M, Bezemer J, de Groot K, Layrolle P. 2004. Incorporation of different antibiotics into carbonated hydroxyapatite coatings on titanium implants, release and antibiotic efficacy. J Control Release. 99:127–137. doi:10.1016/j.jconrel.2004.06.011
   PubMed Web of Science ®Google Scholar
• Stoodley P, Ehrlich GD, Sedghizadeh PP, Hall-Stoodley L, Baratz ME, Altman DT, Sotereanos NG, Costerton JW, Demeo P. 2011. Orthopaedic biofilm infections. Curr Orthop Pract. 22:558–563. doi:10.1097/BCO.0b013e318230efcf
   PubMedGoogle Scholar
• Su Y, Zheng X, Chen Y, Li M, Liu K. 2015. Alteration of intracellular protein expressions as a key mechanism of the deterioration of bacterial denitrification caused by copper oxide nanoparticles . Sci Rep. 5:15824. doi:10.1038/srep15824
   PubMed Web of Science ®Google Scholar
• Sufian MM, Khattak JZK, Yousaf S, Rana MS. 2017. Safety issues associated with the use of nanoparticles in human body. Photodiagnosis Photodyn Ther. 19:67–72. doi:10.1016/j.pdpdt.2017.05.012
   PubMed Web of Science ®Google Scholar
• Sulakvelidze A, Alavidze Z, Morris JG. Jr. 2001. Bacteriophage therapy. Antimicrob Agents Chemother. 45:649–659. doi:10.1128/AAC.45.3.649-659.2001
   PubMed Web of Science ®Google Scholar
• Sullivan MP, McHale KJ, Parvizi J, Mehta S. 2014. Nanotechnology: current concepts in orthopaedic surgery and future directions. Bone Joint J. 96-B:569–573. doi:10.1302/0301-620X.96B5.33606
   PubMedGoogle Scholar
• Sully EK, Malachowa N, Elmore BO, Alexander SM, Femling JK, Gray BM, DeLeo FR, Otto M, Cheung AL, Edwards BS, et al. 2014. Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance. PLoS Pathog. 10:e1004174. doi:10.1371/journal.ppat.1004174
   PubMed Web of Science ®Google Scholar
• Sutton JM, Pritts TA. 2014. Human beta-defensin 3: a novel inhibitor of Staphylococcus-produced biofilm production. Commentary on "Human β-defensin 3 inhibits antibiotic-resistant Staphylococcus biofilm formation". J Surg Res. 186:99–100. doi:10.1016/j.jss.2013.03.077
   PubMed Web of Science ®Google Scholar
• Svensson S, Trobos M, Hoffman M, Norlindh B, Petronis S, Lausmaa J, Suska F, Thomsen P. 2015. A novel soft tissue model for biomaterial-associated infection and inflammation - bacteriological, morphological and molecular observations. Biomaterials. 41:106–121. doi:10.1016/j.biomaterials.2014.11.032
   PubMed Web of Science ®Google Scholar
• Sybesma W, Rohde C, Bardy P, Pirnay JP, Cooper I, Caplin J, Chanishvili N, Coffey A, De Vos D, Scholz AH, et al. 2018. Silk route to the acceptance and re-Implementation of bacteriophage therapy-Part II. Antibiotics (Basel). 7:35. doi:10.3390/antibiotics7020035
   Web of Science ®Google Scholar
• Tande AJ, Patel R. 2014. Prosthetic joint infection. Clin Microbiol Rev. 27:302–345. doi:10.1128/CMR.00111-13
   PubMed Web of Science ®Google Scholar
• Tang K, Zhang XH. 2014. Quorum quenching agents: resources for antivirulence therapy. Mar Drugs. 12:3245–3282. doi:10.3390/md12063245
   PubMed Web of Science ®Google Scholar
• Teirlinck E, Xiong R, Brans T, Forier K, Fraire J, Van Acker H, Matthijs N, De Rycke R, De Smedt SC, Coenye T, et al. 2018. Laser-induced vapour nanobubbles improve drug diffusion and efficiency in bacterial biofilms. Nat Commun. 9:4518 doi:10.1038/s41467-018-06884-w
   PubMed Web of Science ®Google Scholar
• Thakral G, Thakral R, Sharma N, Seth J, Vashisht P. 2014. Nanosurface - the future of implants. J Clin Diagn Res. 8:ZE07–ZE10. doi:10.7860/JCDR/2014/8764.4355
   PubMedGoogle Scholar
• Theinkom F, Singer L, Cieplik F, Cantzler S, Weilemann H, Cantzler M, Hiller K-A, Maisch T, Zimmermann JL. 2019. Antibacterial efficacy of cold atmospheric plasma against Enterococcus faecalis planktonic cultures and biofilms in vitro. PLoS One. 14:e0223925. doi:10.1371/journal.pone.0223925
   PubMed Web of Science ®Google Scholar
• Thoendel M, Kavanaugh JS, Flack CE, Horswill AR. 2011. Peptide signaling in the staphylococci. Chem Rev. 111:117–151. doi:10.1021/cr100370n.
   PubMed Web of Science ®Google Scholar
• Tkhilaishvili T, Lombardi L, Klatt AB, Trampuz A, Di Luca M. 2018. Bacteriophage Sb-1 enhances antibiotic activity against biofilm, degrades exopolysaccharide matrix and targets persisters of Staphylococcus aureus. Int J Antimicrob Agents. 52:842–853. doi:10.1016/j.ijantimicag.2018.09.006
   PubMed Web of Science ®Google Scholar
• Tran PA, O'Brien-Simpson N, Palmer JA, Bock N, Reynolds EC, Webster TJ, Deva A, Morrison WA, O'Connor AJ. 2019. Selenium nanoparticles as anti-infective implant coatings for trauma orthopedics against methicillin-resistant Staphylococcus aureus and epidermidis: in vitro and in vivo assessment. Int J Nanomed. 14:4613–4624. doi:10.2147/IJN.S197737
   PubMed Web of Science ®Google Scholar
• Tran PA, Webster TJ. 2013. Antimicrobial selenium nanoparticle coatings on polymeric medical devices. Nanotechnology. 24:155101. doi:10.1088/0957-4484/24/15/155101
   PubMed Web of Science ®Google Scholar
• Trentin DS, Bonatto F, Zimmer KR, Ribeiro VB, Antunes ALS, Barth AL, Soares GV, Krug C, Baumvol IJR, Macedo AJ, et al. 2014. N2/H2plasma surface modifications of polystyrene inhibit the adhesion of multidrug resistant bacteria. Surf Coat Technol. 245:84–91. doi:10.1016/j.surfcoat.2014.02.046
   Web of Science ®Google Scholar
• Tung H-s, Guss B, Hellman U, Persson L, Rubin K, Rydén C. 2000. A bone sialoprotein-binding protein from Staphylococcus aureus: a member of the staphylococcal Sdr family. Biochem J. 345: 611–619. doi:10.1042/bj3450611
   PubMed Web of Science ®Google Scholar
• Ujino D, Nishizaki H, Higuchi S, Komasa S, Okazaki J. 2019. Effect of plasma treatment of titanium surface on biocompatibility. J Appl Sci. 9:2257. doi:10.3390/app9112257
   Google Scholar
• Ungor D, Dékány I, Csapó E. 2019. Reduction of tetrachloroaurate(Iii) ions with bioligands: role of the thiol and amine functional groups on the structure and optical features of gold nanohybrid systems. Nanomaterials. 9:1229. doi:10.3390/nano9091229
   Web of Science ®Google Scholar
• Urish KL, Bullock AG, Kreger AM, Shah NB, Jeong K, Rothenberger SD, 2018. A multicenter study of irrigation and debridement in total knee arthroplasty Periprosthetic Joint Infection: Treatment Failure Is High . J Arthroplasty. 33:1154–1159. doi:10.1016/j.arth.2017.11.029
   PubMed Web of Science ®Google Scholar
• Valliammai A, Sethupathy S, Priya A, Selvaraj A, Bhaskar JP, Krishnan V, Pandian SK. 2019. 5-Dodecanolide interferes with biofilm formation and reduces the virulence of methicillin-resistant Staphylococcus aureus (MRSA) through up regulation of agr system. Sci Rep. 9:13744. doi:10.1038/s41598-019-50207-y
   PubMed Web of Science ®Google Scholar
• van Vugt TAG, Arts JJ, Geurts JAP. 2019. Antibiotic-loaded polymethylmethacrylate beads and spacers in treatment of orthopedic infections and the role of biofilm formation. Front Microbiol. 10:1626. doi:10.3389/fmicb.2019.01626
   PubMed Web of Science ®Google Scholar
• Vasilev K, Griesser SS, Griesser HJ. 2011. Antibacterial surfaces and coatings produced by plasma techniques. Plasma Processes Polym. 8:1010–1023. 10.1002/ppap.201100097 doi:10.1002/ppap.201100097
   Web of Science ®Google Scholar
• Veerachamy S, Yarlagadda T, Manivasagam G, Yarlagadda PK. 2014. Bacterial adherence and biofilm formation on medical implants: a review. Proc Inst Mech Eng H. 228:1083–1099. doi:10.1177/0954411914556137
   PubMed Web of Science ®Google Scholar
• Verderosa AD, Totsika M, Fairfull-Smith KE. 2019. Bacterial biofilm eradication agents: a current review. Front Chem. 7:824. doi:10.3389/fchem.2019.00824
   PubMed Web of Science ®Google Scholar
• Wang L, Hu C, Shao L. 2017. The antimicrobial activity of nanoparticles: present situation and prospects for the future. Int J Nanomedicine. 12:1227–1249. doi:10.2147/IJN.S121956
   PubMed Web of Science ®Google Scholar
• Wang M, Bhardwaj G, Webster TJ. 2017. Antibacterial properties of PEKK for orthopedic applications. Int J Nanomedicine. 12:6471–6476. doi:10.2147/IJN.S134983
   PubMed Web of Science ®Google Scholar
• Webb JC, Spencer RF. 2007. The role of polymethylmethacrylate bone cement in modern orthopaedic surgery . J Bone Joint Surg Br. 89:851–857. doi:10.1302/0301-620X.89B7.19148
   PubMed Web of Science ®Google Scholar
• Wei G, Lo C, Walsh C, Hiller NL, Marculescu R. 2016. In silico evaluation of the impacts of quorum sensing inhibition (QSI) on strain competition and development of QSI resistance. Sci Rep. 6:35136. doi:10.1038/srep35136
   PubMed Web of Science ®Google Scholar
• Whiteley M, Diggle SP, Greenberg EP. 2017. Progress in and promise of bacterial quorum sensing research. Nature. 551:313–320. doi:10.1038/nature24624
   PubMed Web of Science ®Google Scholar
• Widmer AF. 2001. New developments in diagnosis and treatment of infection in orthopedic implants. Clin Infect Dis. 33: S94–S106. doi:10.1086/321863
   PubMed Web of Science ®Google Scholar
• Wolfram J, Zhu M, Yang Y, Shen J, Gentile E, Paolino D, Fresta M, Nie G, Chen C, Shen H, et al. 2015. Safety of nanoparticles in medicine. Curr Drug Targets. 16:1671–1681. doi:10.2174/1389450115666140804124808
   PubMed Web of Science ®Google Scholar
• Wolska KI, Grudniak AM, Rudnicka Z, Markowska K. 2016. Genetic control of bacterial biofilms. J Appl Genet. 57:225–238. doi:10.1007/s13353-015-0309-2
   PubMed Web of Science ®Google Scholar
• Wu M, Hu K, Xie Y, Liu Y, Mu D, Guo H, Zhang Z, Zhang Y, Chang D, Shi Y. 2018. A novel phage PD-6A3, and its endolysin Ply6A3, with extended lytic activity against Acinetobacter baumannii. Front Microbiol. 9:3302 doi:10.3389/fmicb.2018.03302
   PubMed Web of Science ®Google Scholar
• Wu S, Zhang B, Liu Y, Suo X, Li H. 2018. Influence of surface topography on bacterial adhesion: a review (Review). Biointerphases. 13:060801. doi:10.1116/1.5054057
   PubMed Web of Science ®Google Scholar
• Wu Y, Wang R, Xu M, Liu Y, Zhu X, Qiu J, Liu Q, He P, Li Q. 2019. A novel polysaccharide depolymerase encoded by the phage SH-KP152226 confers specific activity against multidrug-resistant Klebsiella pneumoniae via biofilm degradation. Front Microbiol. 10:2768. doi:10.3389/fmicb.2019.02768
   PubMed Web of Science ®Google Scholar
• Xue C, Song X, Liu M, Ai F, Liu M, Shang Q, Shi X, Li F, He X, Xie L, et al. 2017. A highly efficient, low-toxic, wide-spectrum antibacterial coating designed for 3D printed implants with tailorable release properties. J Mater Chem B. 5:4128–4136. doi:10.1039/C7TB00478H
   PubMed Web of Science ®Google Scholar
• Yan J, Bassler BL. 2019. Surviving as a community: antibiotic tolerance and persistence in bacterial biofilms. Cell Host Microbe. 26:15–21. doi:10.1016/j.chom.2019.06.002
   PubMed Web of Science ®Google Scholar
• Yarwood JM, Bartels DJ, Volper EM, Greenberg EP. 2004. Quorum sensing in Staphylococcus aureus biofilms. J Bacteriol. 186:1838–1850. doi:10.1128/jb.186.6.1838-1850.2004
   PubMed Web of Science ®Google Scholar
• Yazici H, O'Neill MB, Kacar T, Wilson BR, Oren EE, Sarikaya M, Tamerler C. 2016. Engineered chimeric peptides as antimicrobial surface coating agents toward infection-free implants. ACS Appl Mater Interfaces. 8:5070–5081. doi:10.1021/acsami.5b03697
   PubMed Web of Science ®Google Scholar
• Yilmaz C, Colak M, Yilmaz BC, Ersoz G, Kutateladze M, Gozlugol M. 2013. Bacteriophage therapy in implant-related infections: an experimental study. J Bone Joint Surg Am. 95:117–125. doi:10.2106/JBJS.K.01135
   PubMed Web of Science ®Google Scholar
• Yin W, Wang Y, Liu L, He J. 2019. Biofilms: the microbial "Protective Clothing" in Extreme Environments. IJMS. 20:3423. doi:10.3390/ijms20143423
   Google Scholar
• Yu K, Lo JCY, Yan M, Yang X, Brooks DE, Hancock REW, Lange D, Kizhakkedathu JN. 2017. Anti-adhesive antimicrobial peptide coating prevents catheter associated infection in a mouse urinary infection model. Biomaterials. 116:69–81. doi:10.1016/j.biomaterials.2016.11.047
   PubMed Web of Science ®Google Scholar
• Yu P, Wang Z, Marcos-Hernandez M, Zuo P, Zhang D, Powell C, Pan AY, Villagrán D, Wong MS, Alvarez PJJ, et al. 2019. Bottom-up biofilm eradication using bacteriophage-loaded magnetic nanocomposites: a computational and experimental study. Environ Sci: Nano. 6:3539–−3550. doi:10.1039/C9EN00827F
   Web of Science ®Google Scholar
• Zaat S, Broekhuizen C, Riool M. 2010. Host tissue as a niche for biomaterial-associated infection. Future Microbiol. 5:1149–1151. doi:10.2217/fmb.10.89
   PubMed Web of Science ®Google Scholar
• Zabielska R, Agnieszka T, Kunicka-Styczyńska A. 2016. Methods for eradication of the biofilms formed by opportunistic pathogens using novel techniques- a review. biologica. 12:26–37. doi:10.1515/fobio-2016-0003
   Google Scholar
• Zaborowska M, Tillander J, Brånemark R, Hagberg L, Thomsen P, Trobos M. 2017. Biofilm formation and antimicrobial susceptibility of staphylococci and enterococci from osteomyelitis associated with percutaneous orthopaedic implants. J Biomed Mater Res B Appl Biomater. 105:2630–2640. doi:10.1002/jbm.b.33803
   PubMed Web of Science ®Google Scholar
• Zhang J. 2011. Silver-coated zinc oxide nano antibacterial synthesis and antibacterial activity characterization. In: 2011 International Conference on Electronics and Optoelectronics (ICEOE), Vol. 3, Dalian, Liaoning (IEEE, 2011), pp. V3-94–V3-98.
   Google Scholar
• Zhang L, Sun L, Wei R, Gao Q, He T, Xu C, Liu X, Wang R. 2017. Intracellular Staphylococcus aureus control by virulent bacteriophages within MAC-T bovine mammary epithelial cells. Antimicrob Agents Chemother. 61:e01990–16. doi:10.1128/AAC.01990-16
   PubMed Web of Science ®Google Scholar
• Zhang W, Li Y, Niu J, Chen Y. 2013. Photogeneration of reactive oxygen species on uncoated silver, gold, nickel, and silicon nanoparticles and their antibacterial effects. Langmuir. 29:4647–4651. doi:10.1021/la400500t
   PubMed Web of Science ®Google Scholar
• Zhang Z, Shively JE. 2013. Acceleration of bone repair in NOD/SCID mice by human monoosteophils, novel LL-37-activated monocytes. PLoS One. 8:e67649 doi:10.1371/journal.pone.0067649
   PubMed Web of Science ®Google Scholar
• Zhao L, Chu PK, Zhang Y, Wu Z. 2009. Antibacterial coatings on titanium implants. J Biomed Mater Res B Appl Biomater. 91:470–480. doi:10.1002/jbm.b.31463
   PubMed Web of Science ®Google Scholar
• Zhu C, Tan H, Cheng T, Shen H, Shao J, Guo Y, Shi S, Zhang X. 2013. Human β-defensin 3 inhibits antibiotic-resistant Staphylococcus biofilm formation. J Surg Res. 183:204–213. doi:10.1016/j.jss.2012.11.048
   PubMed Web of Science ®Google Scholar
• Zhukova LV. 2015. Evidence for compression of Escherichia coli K12 cells under the effect of TiO2 nanoparticles. ACS Appl Mater Interfaces. 7:27197–27205. doi:10.1021/acsami.5b08042
   PubMed Web of Science ®Google Scholar
• Zilberman M, Elsner JJ. 2008. Antibiotic-eluting medical devices for various applications. J Control Release. 130:202–215. doi:10.1016/j.jconrel.2008.05.020
   PubMed Web of Science ®Google Scholar
• Zimmerli W, Trampuz A, Ochsner PE. 2004. Prosthetic-joint infections. N Engl J Med. 351:1645–1654. doi:10.1056/NEJMra040181
   PubMed Web of Science ®Google Scholar
• Zywiel MG, Mont MA. 2011. Orthopedic implant approval: achieving the right balance. Expert Rev Med Devices. 8:405–408. doi:10.1586/erd.11.38
   PubMed Web of Science ®Google Scholar