Exploring the anti-caries properties of baicalin against Streptococcus mutans: an in vitro study

References

• Balasubramanian AR, Vasudevan S, Shanmugam K, Lévesque CM, Solomon AP, Neelakantan P. 2021. Combinatorial effects of trans-cinnamaldehyde with fluoride and chlorhexidine on Streptococcus mutans. J Appl Microbiol. 130:382–393. doi:10.1111/jam.14794
   PubMed Web of Science ®Google Scholar
• Banas JA, Drake DR. 2018. Are the mutans streptococci still considered relevant to understanding the microbial etiology of dental caries? BMC Oral Health. 18:129.doi:10.1186/s12903-018-0595-2
   PubMed Web of Science ®Google Scholar
• Buzalaf MAR, Pessan JP, Honório HM, ten Cate JM. 2011. Mechanisms of action of fluoride for caries control. Monogr Oral Sci. 22: 97–114. doi:10.1159/000325151
   PubMedGoogle Scholar
• Cruz CD, Shah S, Tammela P. 2018. Defining conditions for biofilm inhibition and eradication assays for Gram-positive clinical reference strains. BMC Microbiol. 18:173 doi:10.1186/s12866-018-1321-6
   PubMed Web of Science ®Google Scholar
• Dou J, Wang Z, Ma L, Peng B, Mao K, Li C, Su M, Zhou C, Peng G. 2018. Baicalein and baicalin inhibit colon cancer using two distinct fashions of apoptosis and senescence. Oncotarget. 9:20089–20102. doi:10.18632/oncotarget.24015
   PubMedGoogle Scholar
• Du Z, Huang Y, Chen Y, Chen Y. 2019. Combination effects of baicalin with levofloxacin against biofilm-related infections. Am J Transl Res. 11:1270–1281.
   PubMed Web of Science ®Google Scholar
• Duan C, Matsumura S, Kariya N, Nishimura M, Shimono T. 2007. In vitro antibacterial activities of Scutellaria baicalensis Georgi against cariogenic bacterial. Pediatr Dent J. 17:58–64. doi:10.1016/S0917-2394(07)70096-4
   Google Scholar
• Featherstone JDB. 2008. Dental caries: a dynamic disease process. Aust Dent J. 53:286–291. doi:10.1111/j.1834-7819.2008.00064.x
   PubMedGoogle Scholar
• Hardie KR, Heurlier K. 2008. Establishing bacterial communities by “ 'word of mouth': LuxS and autoinducer 2 in biofilm development” . Nat Rev Microbiol. 6:635–643. doi:10.1038/nrmicro1916
   PubMed Web of Science ®Google Scholar
• He Z, Huang Z, Jiang W, Zhou W. 2019. Antimicrobial activity of cinnamaldehyde on Streptococcus mutans biofilms. Front Microbiol. 10:2241.doi:10.3389/fmicb.2019.02241
   PubMed Web of Science ®Google Scholar
• James SL, Abate D, Abate KH, Abay SM, Abbafati C, Abbasi N, Abbastabar H, Abd-Allah F, Abdela J, Abdelalim A, et al. 2018. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 392:1789–1858. doi:10.1016/S0140-6736(18)32279-7
   PubMed Web of Science ®Google Scholar
• Jelić D, Lower-Nedza AD, Brantner AH, Blažeković B, Bian B, Yang J, Brajša K, Vladimir-Knežević S. 2016. Baicalin and baicalein inhibit Src tyrosine kinase and production of IL-6. Navarrete-Vazquez G, editor. J Chem. 2016:1–6. doi:10.1155/2016/2510621
   Web of Science ®Google Scholar
• Kaur G, Balamurugan P, Princy SA. 2017. Inhibition of the quorum sensing system (ComDE Pathway) by aromatic 1,3-di-m-tolylurea (DMTU): cariostatic effect with fluoride in Wistar rats. Front Cell Infect Microbiol. 7:313.doi:10.3389/fcimb.2017.00313
   PubMed Web of Science ®Google Scholar
• Kaur G, Rajesh S, Princy SA. 2015. Plausible drug targets in the Streptococcus mutans quorum sensing pathways to combat dental biofilms and associated risks. Indian J Microbiol. 55:349–356. doi:10.1007/s12088-015-0534-8
   PubMed Web of Science ®Google Scholar
• Kim YR, Nam SH. 2017. Caries prevention effect of Scutellaria radix mouthwash. Biomed Res. 28:6090–6094.
   Google Scholar
• Koo H, Xiao J, Klein MI, Jeon JG. 2010. Exopolysaccharides produced by Streptococcus mutans glucosyltransferases modulate the establishment of microcolonies within multispecies biofilms. J Bacteriol. 192:3024–3032. doi:10.1128/JB.01649-09
   PubMed Web of Science ®Google Scholar
• Kyaw BM, Arora S, Lim CS. 2012. Bactericidal antibiotic-phytochemical combinations against methicillin resistant Staphylococcus aureus. Braz J Microbiol. 43:938–945. doi:10.1590/S1517-838220120003000013
   PubMed Web of Science ®Google Scholar
• Leung KC-F, Seneviratne CJ, Li X, Leung PC, Lau CBS, Wong C-H, Pang KY, Wong CW, Wat E, Jin L. 2016. Synergistic antibacterial effects of nanoparticles encapsulated with Scutellaria baicalensis and pure chlorhexidine on oral bacterial biofilms. Nanomater (Basel, Switzerland). 6:61. doi:10.3390/nano6040061
   PubMedGoogle Scholar
• Liao Y, Brandt BW, Li J, Crielaard W, Van Loveren C, Deng DM. 2017. Fluoride resistance in Streptococcus mutans: a mini review. J Oral Microbiol. 9:1344509. doi:10.1080/20002297.2017.1344509
   PubMed Web of Science ®Google Scholar
• Luo J, Dong B, Wang K, Cai S, Liu T, Cheng X, Lei D, Chen Y, Li Y, Kong J, et al. 2017. Baicalin inhibits biofilm formation, attenuates the quorum sensing-controlled virulence and enhances Pseudomonas aeruginosa clearance in a mouse peritoneal implant infection model. PLoS One. 12:e0176883–e0176883. doi:10.1371/journal.pone.0176883
   PubMed Web of Science ®Google Scholar
• Luo W, Wang C-Y, Jin L. 2012. Baicalin downregulates Porphyromonas gingivalis lipopolysaccharide-upregulated IL-6 and IL-8 expression in human oral keratinocytes by negative regulation of TLR signaling. PLoS One. 7:e51008.doi:10.1371/journal.pone.0051008
   PubMed Web of Science ®Google Scholar
• Lussi A, Schlueter N, Rakhmatullina E, Ganss C. 2011. Dental erosion – an overview with emphasis on chemical and histopathological aspects. Caries Res. 45: 2–12. doi:10.1159/000325915
   PubMed Web of Science ®Google Scholar
• Matsui R, Cvitkovitch D. 2010. Acid tolerance mechanisms utilized by Streptococcus mutans. Future Microbiol. 5:403–417. doi:10.2217/fmb.09.129
   PubMed Web of Science ®Google Scholar
• Matsumoto-Nakano M. 2018. Role of Streptococcus mutans surface proteins for biofilm formation. Jpn Dent Sci Rev. 54:22–29. doi:10.1016/j.jdsr.2017.08.002
   PubMed Web of Science ®Google Scholar
• Merritt JH, Kadouri DE, O’Toole GA. 2011. Growing and analyzing static biofilms. Curr Protoc Microbiol. 22:1B.1.1–1B.1.18.
   Google Scholar
• Mgbeahuruike EE, Stålnacke M, Vuorela H, Holm Y. 2019. Antimicrobial and synergistic effects of commercial piperine and Piperlongumine in combination with conventional antimicrobials. Antibiot (Basel, Switzerland). 8:55.
   Web of Science ®Google Scholar
• Moon Y-H, Lee Y-H, Min B-S, Bae K-H. 1997. Antibacterial constituents from Scutellariae radix against Streptococcus mutans OMZ176. Korean J Pharmacogn. 28:99–103.
   Google Scholar
• Nagasawa R, Sato T, Nomura N, Nakamura T, Senpuku H. 2020. Potential risk of spreading resistance genes within extracellular-DNA-dependent biofilms of Streptococcus mutans in response to cell envelope stress induced by sub-MICs of bacitracin. Drake HL, editor. Appl Environ Microbiol. 86:e00770–20. doi:10.1128/AEM.00770-20
   PubMed Web of Science ®Google Scholar
• O’Toole GA. 2010. Microtiter dish biofilm formation assay. J Vis Exp. (47):2437. doi:10.3791/2437
   Google Scholar
• Paek J-Y, Kim Y-H, Kwon H-J, Kim E-N, Kim W-J, Han M-D. 2008. Effects of antibacteria and adhesive inhibition of Scutellaria baicalensis extract on Streptococcus mutans. J Korean Soc Dent Hyg. 8:367–373.
   Google Scholar
• Paula AJ, Hwang G, Koo H. 2020. Dynamics of bacterial population growth in biofilms resemble spatial and structural aspects of urbanization. Nat Commun. 11:1354.doi:10.1038/s41467-020-15165-4
   PubMed Web of Science ®Google Scholar
• Peng L-Y, Yuan M, Wu Z-M, Song K, Zhang C-L, An Q, Xia F, Yu J-L, Yi P-F, Fu B-D, et al. 2019. Anti-bacterial activity of baicalin against APEC through inhibition of quorum sensing and inflammatory responses. Sci Rep. 9:4063.doi:10.1038/s41598-019-40684-6
   PubMed Web of Science ®Google Scholar
• Priya A, Pandian SK. 2020. Piperine impedes biofilm formation and hyphal morphogenesis of Candida albicans. Front Microbiol. 11:756.doi:10.3389/fmicb.2020.00756
   PubMed Web of Science ®Google Scholar
• Quecan BXV, Santos JTC, Rivera MLC, Hassimotto NMA, Almeida FA, Pinto UM. 2019. Effect of quercetin rich onion extracts on bacterial quorum sensing. Front Microbiol. 10:867.doi:10.3389/fmicb.2019.00867
   PubMed Web of Science ®Google Scholar
• Sato Y, Yamamoto Y, Kizaki H. 1997. Cloning and sequence analysis of the gbpC gene encoding a novel glucan-binding protein of Streptococcus mutans. Infect Immun. 65:668– 675. doi:10.1128/IAI.65.2.668-675.1997
   PubMed Web of Science ®Google Scholar
• Sato Y, Yamamoto Y, Kizaki H. 2000. Xylitol-induced elevated expression of the gbpC gene in a population of Streptococcus mutans cells. Eur J Oral Sci. 108:538–545. doi:10.1034/j.1600-0722.2000.00928.x
   PubMed Web of Science ®Google Scholar
• Senadheera D, Krastel K, Mair R, Persadmehr A, Abranches J, Burne RA, Cvitkovitch DG. 2009. Inactivation of vicK affects acid production and acid survival of Streptococcus mutans. JB. 191:6415–6424. doi:10.1128/JB.00793-09
   Google Scholar
• Shanmugam K, Sarveswari HB, Udayashankar A, Swamy SS, Pudipeddi A, Shanmugam T, Solomon AP, Neelakantan P. 2020. Guardian genes ensuring subsistence of oral Streptococcus mutans. Crit Rev Microbiol. 46:1–17. doi:10.1080/1040841X.2020.1796579
   Web of Science ®Google Scholar
• Takahashi N, Nyvad B. 2011. The role of bacteria in the caries process: Ecological perspectives. J Dent Res. 90:294–303. doi:10.1177/0022034510379602
   PubMed Web of Science ®Google Scholar
• Tanner ACR, Kressirer CA, Rothmiller S, Johansson I, Chalmers NI. 2018. The caries microbiome: implications for reversing dysbiosis. Adv Dent Res. 29:78–85. doi:10.1177/0022034517736496
   PubMedGoogle Scholar
• Tao Y, Zhan S, Wang Y, Zhou G, Liang H, Chen X, Shen H. 2018. Baicalin, the major component of traditional Chinese medicine Scutellaria baicalensis induces colon cancer cell apoptosis through inhibition of oncomiRNAs. Sci Rep. 8:14477.doi:10.1038/s41598-018-32734-2
   PubMed Web of Science ®Google Scholar
• Thurnheer T, Belibasakis GN. 2018. Effect of sodium fluoride on oral biofilm microbiota and enamel demineralization. Arch Oral Biol. 89:77–83. doi:10.1016/j.archoralbio.2018.02.010
   PubMed Web of Science ®Google Scholar
• Wang G, Gao Y, Wang H, Niu X, Wang J. 2018. Baicalin weakens Staphylococcus aureus pathogenicity by targeting sortase B. Front Cell Infect Microbiol. 8:418.doi:10.3389/fcimb.2018.00418
   PubMed Web of Science ®Google Scholar
• Wang J, Jiao H, Meng J, Qiao M, Du H, He M, Ming K, Liu J, Wang D, Wu Y. 2019. Baicalin inhibits biofilm formation and the quorum-sensing system by regulating the MsrA drug efflux pump in Staphylococcus saprophyticus. Front Microbiol. 10:2800.doi:10.3389/fmicb.2019.02800
   PubMed Web of Science ®Google Scholar
• Zhang K, He M, Wang F, Zhang H, Li Y, Yang J, Wu C. 2019. Revealing antidepressant mechanisms of baicalin in hypothalamus through systems approaches in corticosterone- induced depressed mice. Front Neurosci. 13:834.doi:10.3389/fnins.2019.00834
   PubMed Web of Science ®Google Scholar
• Zhang S, Hu B, Xu J, Ren Q, Wang Z, Wang S, Dong Y, Yang G. 2020. Baicalin suppress growth and virulence-related factors of methicillin-resistant Staphylococcus aureus in vitro and vivo. Microb Pathog. 139:103899.doi:10.1016/j.micpath.2019.103899
   PubMed Web of Science ®Google Scholar
• Zhang C, Guo X, Ma Z, Zhai X. 2009. Chinese herbal medicine composition with bacteriostasis, anti-inflammation hemostasia effect [Internet]. [accessed 2021 Jan 6]. https://patentimages.storage.googleapis.com/c2/fa/90/07c86c77fffc01/CN101357154A.pdf.
   Google Scholar
• Zhou T, Zhang A, Kuang G, Gong X, Jiang R, Lin D, Li J, Li H, Zhang X, Wan J, et al. 2017. Baicalin inhibits the metastasis of highly aggressive breast cancer cells by reversing epithelial-to-mesenchymal transition by targeting β-catenin signaling. Oncol Rep. 38:3599–3607. doi:10.3892/or.2017.6011
   PubMed Web of Science ®Google Scholar
• Zhu W, Ma S, Qu R, Kang D, Liu Y. 2006. Antidepressant effect of baicalin extracted from the root of Scutellaria baicalensis in mice and rats. Pharm Biol. 44:503–510. doi:10.1080/13880200600878684
   Web of Science ®Google Scholar