Experimental Study on the Prevention of Posttraumatic Osteoarthritis in the Rabbit Knee Using a Hinged External Fixator in Combination with Exercises

References

• Chubinskaya S, Wimmer MA. Key pathways to prevent posttraumatic arthritis for future molecule-based therapy. Cartilage 2013;Jul4(3_suppl):13S–21S.
   PubMed Web of Science ®Google Scholar
• Brown TD, Johnston RC, Saltzman CL, Marsh JL, Buckwalter JA. Posttraumatic osteoarthritis: a first estimate of incidence, prevalence, and burden of disease. J Orthop Trauma. 2006;Nov–Dec20(10):739–744.
   PubMed Web of Science ®Google Scholar
• Lafeber FP, Intema F, Van Roermund PM, Marijnissen AC. Unloading joints to treat osteoarthritis, including joint distraction. Curr Opin Rheumatol. 2006;Sep18(5):519–525.
   PubMed Web of Science ®Google Scholar
• Chen Y, Sun Y, Pan X, Ho K, Li G. Joint distraction attenuates osteoarthritis by reducing secondary inflammation, cartilage degeneration and subchondral bone aberrant change. Osteoarthritis Cartilage 2015;Oct23(10):1728–1735.
   PubMed Web of Science ®Google Scholar
• Wiegant K, Intema F, van Roermund PM, et al. Evidence of cartilage repair by joint distraction in a canine model of osteoarthritis. Arthritis Rheumatol. 2015;Feb67(2):465–474.
   PubMed Web of Science ®Google Scholar
• Mastbergen SC, Saris DB, Lafeber FP. Functional articular cartilage repair: here, near, or is the best approach not yet clear? Nat Rev Rheumatol. 2013;May9(5):277–290.
   PubMed Web of Science ®Google Scholar
• Chen Y, Sun Y, Pan X, Ho K, Li G. Joint distraction attenuates osteoarthritis by reducing secondary inflammation, cartilage degeneration and subchondral bone aberrant change. Osteoarthritis and Cartilage. [Research Support, Non-U.S. Gov't]. 2015;23(10):1728–1735. Oct
   PubMed Web of Science ®Google Scholar
• Wiegant K, Intema F, van Roermund PM, et al. Evidence of cartilage repair by joint distraction in a canine model of osteoarthritis. Arthritis Rheumatol. [Comparative Study Research Support, Non-U.S. Gov't]. 2015;Feb67(2):465–474.
   PubMed Web of Science ®Google Scholar
• van der Woude JA, Wiegant K, van Heerwaarden RJ, et al. Knee joint distraction compared with total knee arthroplasty: a randomised controlled trial. Bone Joint J. 2017;Jan99-B(1):51–58.
   PubMedGoogle Scholar
• van der Woude JAD, Wiegant K, van Heerwaarden RJ, et al. Knee joint distraction compared with high tibial osteotomy: a randomized controlled trial. Knee Surg Sports Traumatol Arthrosc. 2017;Mar25(3):876–886.
   PubMed Web of Science ®Google Scholar
• van der Woude JAD, Wiegant K, van Roermund PM, et al. Five-year follow-up of knee joint distraction: clinical benefit and cartilaginous tissue repair in an open uncontrolled prospective study. Cartilage. 2017;Jul8(3):263–271.
   PubMed Web of Science ®Google Scholar
• van der Woude JA, van Heerwaarden RJ, Spruijt S, et al. Six weeks of continuous joint distraction appears sufficient for clinical benefit and cartilaginous tissue repair in the treatment of knee osteoarthritis. Knee 2016;Oct23(5):785–791.
   PubMed Web of Science ®Google Scholar
• Lieberthal J, Sambamurthy N, Scanzello CR. Inflammation in joint injury and post-traumatic osteoarthritis. Osteoarthritis Cartilage. 2015;Nov23(11):1825–1834.
   PubMed Web of Science ®Google Scholar
• Chadjichristos C, Ghayor C, Kypriotou M, et al. Sp1 and Sp3 transcription factors mediate interleukin-1 beta down-regulation of human type II collagen gene expression in articular chondrocytes. J Biol Chem 2003; Oct 10278(41):39762–39772.
   PubMed Web of Science ®Google Scholar
• Seguin CA, Bernier SM. TNFalpha suppresses link protein and type II collagen expression in chondrocytes: Role of MEK1/2 and NF-kappaB signaling pathways. J Cell Physiol. 2003; Dec197(3):356–369.
   PubMed Web of Science ®Google Scholar
• Batista ML, Jr., Rosa JC, Lopes RD, et al. Exercise training changes IL-10/TNF-alpha ratio in the skeletal muscle of post-MI rats. Cytokine. [Research Support, Non-U.S. Gov't]. 2010;49(1):102–108. Jan
   Google Scholar
• Chang NJ, Lin CC, Shie MY, et al. Positive effects of cell-free porous PLGA implants and early loading exercise on hyaline cartilage regeneration in rabbits. Acta Biomater. 2015;Dec28:128–137.
   PubMed Web of Science ®Google Scholar
• Chang NJ, Lee KW, Chu CJ, et al. A preclinical assessment of early continuous passive motion and treadmill therapeutic exercises for generating chondroprotective effects after anterior cruciate ligament rupture. Am J Sports Med. 2017;Aug45(10):2284–2293.
   PubMed Web of Science ®Google Scholar
• Chang NJ, Shie MY, Lee KW, Chou PH, Lin CC, Chu CJ. Can early rehabilitation prevent posttraumatic osteoarthritis in the patellofemoral joint after anterior cruciate ligament rupture? understanding the pathological features. Int J Mol Sci. 2017;Apr14(4):18.
   Google Scholar
• Fu X, Lin L, Zhang J, Yu C. Assessment of the efficacy of joint lavage in rabbits with osteoarthritis of the knee. J Orthop Res. 2009;27(1):91–96. Jan
   PubMed Web of Science ®Google Scholar
• Abouheif MM, Nakamura M, Deie M, et al. Repair of a large osteochondral defect in the knee joint using autologous and artificial bone graft combined with motion preserving distraction arthroplasty: a case report. Arch Orthop Trauma Surg. 2010;Feb130(2):231–236.
   PubMed Web of Science ®Google Scholar
• van Valburg AA, van Roy HL, Lafeber FP, Bijlsma JW. Beneficial effects of intermittent fluid pressure of low physiological magnitude on cartilage and inflammation in osteoarthritis. An in vitro study. J Rheumatol. 1998; Mar25(3):515–520.
   PubMed Web of Science ®Google Scholar
• Omata S, Sonokawa S, Sawae Y, Murakami T. Effects of both vitamin C and mechanical stimulation on improving the mechanical characteristics of regenerated cartilage. Biochem Biophys Res Commun. [Research Support, Non-U.S. Gov't]. 2012;424(4):724–729. Aug 10
   PubMed Web of Science ®Google Scholar
• DiFederico E, Shelton JC, Bader DL. Complex mechanical conditioning of cell-seeded agarose constructs can influence chondrocyte biosynthetic activity. Biotechnol Bioeng. 2017;114(7):1614–1625. Jul
   PubMed Web of Science ®Google Scholar
• Omata S, Sonokawa S, Sawae Y, Murakami T. Effects of both vitamin C and mechanical stimulation on improving the mechanical characteristics of regenerated cartilage. Biochem Biophys Res Commun. 2012;424(4):724–729. Aug 10
   PubMed Web of Science ®Google Scholar