843
Views
1
CrossRef citations to date
0
Altmetric
Commentary

Primary Gross Tumor Volume (pGTV) and Tumor Response in Locally Advanced Rectal Cancer (LARC). Is There Any Correlation?

, MD, MSc, PhD, , MD, MSc, PhD, , MD, MSc, PhD, , MD, PhD, FRCP & , MD, MSc, PhD

References

  • Sauer R, Liersch T, Merkel S, et al. Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years. J Clin Oncol. 2012;30:1926–1933. doi:10.1200/JCO.2011.40.1836.
  • Hashiguchi Y, Muro K, Saito Y, et al. Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer. Int J Clin Oncol. 2019. [Epub ahead of print].
  • Schmoll H-J, Haustermans K, Price TJ, et al. Preoperative chemoradiotherapy and postoperative chemotherapy with capecitabine +/– oxaliplatin in locally advanced rectal cancer: final results of PETACC-6. J Clin Oncol. 2018;36(suppl; abstr 3500). doi:10.1200/JCO.2018.36.15_suppl.3500.
  • De Felice F, Izzo L, Musio D, et al. Clinical predictive factors of pathologic complete response in locally advanced rectal cancer. Oncotarget. 2016;7:33374–33380. doi:10.18632/oncotarget.8133.
  • Studer G, Lutolf UM, El-Bassiouni M, et al. Volumetric staging (VS) is superior to TNM and AJCC staging in predicting outcome of head and neck cancer treated with IMRT. Acta Oncol. 2007;46:386–394. doi:10.1080/02841860600815407.
  • Liu W, Li Y, Zhu H, et al. The relationship between primary gross tumor volume and tumor response of locally advanced rectal cancer: pGTV as a more accurate tumor size indicator. J Invest Surg. 2021; 34(2):181–190. doi:10.1080/08941939.2019.1615153.
  • Becker K, Mueller JD, Schulmacher C, et al. Histomorphology and grading of regression in gastric carcinoma treated with neoadjuvant chemotherapy. Cancer. 2003;98:1521–1530. doi:10.1002/cncr.11660.
  • Johnson CR, Thames HD, Huang DT, et al. The tumor volume and clonogen number relationship: tumor control predictions based upon tumor volume estimates derived from computed tomography. Int J Radiat Oncol Biol Phys. 1995;33(2):281–287. doi:10.1016/0360-3016(95)00119-J.
  • Rutkowski T. The role of tumor volume in radiotherapy of patients with head and neck cancer. Radiat Oncol. 2014;9:23doi:10.1186/1748-717X-9-23.
  • Lambregts DM, Rao SX, Sassen S, et al. MRI and diffusion-weighted MRI volumetry for identification of complete tumor responders after preoperative chemoradiotherapy in patients with rectal cancer: a bi-institutional validation study. Ann Surg. 2015;262(6):1034–1039. doi:10.1097/SLA.0000000000000909.
  • Palmisano A, Esposito A, Di Chiara A, et al. Could early tumour volume changes assessed on morphological MRI predict the response to chemoradiation therapy in locally-advanced rectal cancer? Clin Radiol. 2018;73(6):555–563. doi:10.1016/j.crad.2018.01.007.
  • Patel SV, Roxburgh CS, Vakiani E, et al. Distance to the anal verge is associated with pathologic complete response to neoadjuvant therapy in locally advanced rectal cancer. J Surg Oncol. 2016;114(5):637–641. doi:10.1002/jso.24358.
  • Ward WH, Sigurdson ER, Esposito AC, et al. Pathologic response following treatment for locally advanced rectal cancer: does location matter? J Surg Res. 2018; 224:215–221. doi:10.1016/j.jss.2017.11.072.
  • Hsu CY, Wang CW, Kuo CC, et al. Tumor compactness improves the preoperative volumetry-based prediction of the pathological complete response of rectal cancer after preoperative concurrent chemoradiotherapy. Oncotarget. 2017;8(5):7921–7934. doi:10.18632/oncotarget.13855.
  • Hu H, Huang J, Lan P, et al. CEA clearance pattern as a predictor of tumor response to neoadjuvant treatment in rectal cancer: a post-hoc analysis of FOWARC trial. BMC Cancer. 2018;18(1):1145 doi:10.1186/s12885-018-4997-y.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.