High Expression of TRIM15 Is Associated with Tumor Invasion and Predicts Poor Prognosis in Patients with Gastric Cancer

References

• Torre LA, Bray F, Siegel RL, et al. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65(2):87–108. doi:10.3322/caac.21262.
   PubMed Web of Science ®Google Scholar
• Allemani C, Matsuda T, Di Carlo V, et al. Global surveillance of trends in cancer survival 2000–14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries. Lancet. 2018;391(10125):1023–1075. doi:10.1016/S0140-6736(17)33326-3.
   PubMed Web of Science ®Google Scholar
• Stock M, Otto F. Gene deregulation in gastric cancer. Gene. 2005;360(1):1–19. doi:10.1016/j.gene.2005.06.026.
   PubMed Web of Science ®Google Scholar
• Hatakeyama S. TRIM proteins and cancer. Nat Rev Cancer. 2011;11(11):792–804. doi:10.1038/nrc3139.
   PubMed Web of Science ®Google Scholar
• Heaton SM, Borg N. A, Dixit VM. Ubiquitin in the activation and attenuation of innate antiviral immunity. J Exp Med. 2016;213(1):1–13. doi:10.1084/jem.20151531.
   PubMed Web of Science ®Google Scholar
• Mandell MA, Jain A, Arko-Mensah J, et al. TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition. Dev Cell. 2014;30(4):394–409. doi:10.1016/j.devcel.2014.06.013.
   PubMed Web of Science ®Google Scholar
• Rajsbaum R, Garcia-Sastre A, Versteeg GA. TRIMmunity: the roles of the TRIM E3-ubiquitin ligase family in innate antiviral immunity. J Mol Biol. 2014;426(6):1265–1284.
   PubMed Web of Science ®Google Scholar
• Borden KL. RING fingers and B-boxes: zinc-binding protein-protein interaction domains. Biochem Cell Biol. 1998;76(2–3):351–358. doi:10.1139/bcb-76-2-3-351.z.
   PubMed Web of Science ®Google Scholar
• Ozato K, Shin DM, Chang TH, et al. TRIM family proteins and their emerging roles in innate immunity. Nat Rev Immunol. 2008;8(11):849–860. 3rd. doi:10.1038/nri2413.
   PubMed Web of Science ®Google Scholar
• Lv D, Li Y, Zhang W, et al. TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma. Nat Commun. 2017;8(1):1454. doi:10.1038/s41467-017-01731-w.
   PubMedGoogle Scholar
• Wei C, Cheng J, Zhou B, et al. Tripartite motif containing 28 (TRIM28) promotes breast cancer metastasis by stabilizing TWIST1 protein. Sci Rep. 2016;6(1):29822. doi:10.1038/srep29822.
   PubMedGoogle Scholar
• Zeng SX, Cai QC, Guo CH, et al. High expression of TRIM29 (ATDC) contributes to poor prognosis and tumor metastasis by inducing epithelialmesenchymal transition in osteosarcoma. Oncol Rep. 2017;38(3):1645–1654. doi:10.3892/or.2017.5842.
   PubMed Web of Science ®Google Scholar
• Groner AC, Cato L, de Tribolet-Hardy J, et al. TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer. Cancer cell. 2016;29(6):846–858. doi:10.1016/j.ccell.2016.04.012.
   PubMed Web of Science ®Google Scholar
• Ai L, Kim WJ, Alpay M, et al. TRIM29 suppresses TWIST1 and invasive breast cancer behavior. Cancer Res. 2014;74(17):4875–4887. doi:10.1158/0008-5472.CAN-13-3579.
   PubMed Web of Science ®Google Scholar
• Qin X, Qiu F, Zou Z. TRIM25 is associated with cisplatin resistance in non-small-cell lung carcinoma A549 cell line via downregulation of 14-3-3σ. Biochem Biophys Res Commun. 2017;493(1):568–572. doi:10.1016/j.bbrc.2017.08.151.
   PubMed Web of Science ®Google Scholar
• Nisole S, Stoye JP, Saïb A. TRIM family proteins: retroviral restriction and antiviral defence. Nat Rev Microbiol. 2005;3(10):799–808. doi:10.1038/nrmicro1248.
   PubMed Web of Science ®Google Scholar
• Uchil PD, Hinz A, Siegel S, et al. TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. J Virol. 2013;87(1):257–272. doi:10.1128/JVI.01804-12.
   PubMed Web of Science ®Google Scholar
• Lee OH, Lee J, Lee KH, et al. Role of the focal adhesion protein TRIM15 in colon cancer development. Biochim Biophys Acta. 2015;1853(2):409–421. doi:10.1016/j.bbamcr.2014.11.007.
   PubMed Web of Science ®Google Scholar
• Zhu Y, Qiu P, Ji Y. TCGA-assembler: open-source software for retrieving and processing TCGA data. Nat Methods. 2014;11(6):599–600. doi:10.1038/nmeth.2956.
   PubMed Web of Science ®Google Scholar
• Robinson MD, Oshlack A. A scaling normalization method for differential expression analysis of RNA-seq data. Genome Biol. 2010;11(3):R25. doi:10.1186/gb-2010-11-3-r25.
   PubMed Web of Science ®Google Scholar
• Chen L, Min L, Wang X, et al. Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling Loop. Cancer Res. 2015;75(18):3832–3841. doi:10.1158/0008-5472.CAN-14-3690.
   PubMed Web of Science ®Google Scholar
• Thiery JP, Acloque H, Huang RY, et al. Epithelial-mesenchymal transitions in development and disease. Cell. 2009;139(5):871–890. doi:10.1016/j.cell.2009.11.007.
   PubMed Web of Science ®Google Scholar
• Uchil PD, Pawliczek T, Reynolds TD, et al. TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly. J Cell Sci. 2014;127 (18):3928–3942. doi:10.1242/jcs.143537.
   PubMed Web of Science ®Google Scholar
• Napolitano LM, Jaffray EG, Hay RT, et al. Functional interactions between ubiquitin E2 enzymes and TRIM proteins. Biochem J. 2011; 434(2):309–319. doi:10.1042/BJ20101487.
   PubMedGoogle Scholar
• Sulzmaier FJ, Jean C, Schlaepfer DD. FAK in cancer: mechanistic findings and clinical applications. Nat Rev Cancer. 2014;14(9):598–610. doi:10.1038/nrc3792.
   PubMed Web of Science ®Google Scholar
• Lietha D, Cai X, Ceccarelli DF, et al. Structural basis for the autoinhibition of focal adhesion kinase. Cell. 2007;129(6):1177–1187. doi:10.1016/j.cell.2007.05.041.
   PubMed Web of Science ®Google Scholar
• Du T, Qu Y, Li J, et al. Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway. Mol Cancer. 2014;13(1):100. doi:10.1186/1476-4598-13-100.
   PubMedGoogle Scholar
• Wang J, Wen T, Li Z, et al. MicroRNA-1224 Inhibits Tumor Metastasis in Intestinal-Type Gastric Cancer by Directly Targeting FAK. Front Oncol. 2019;9:222doi:10.3389/fonc.2019.00222.
   PubMed Web of Science ®Google Scholar
• Jia L, Uekita T, Sakai R. Hyperphosphorylated cortactin in cancer cells plays an inhibitory role in cell motility. Mol Cancer Res. 2008; 6(4):654–662. doi:10.1158/1541-7786.MCR-07-0220.
   PubMed Web of Science ®Google Scholar
• Chen DL, Wang ZQ, Ren C, et al. Abnormal expression of paxillin correlates with tumor progression and poor survival in patients with gastric cancer. J Transl Med. 2013;11(1):277. doi:10.1186/1479-5876-11-277.
   PubMedGoogle Scholar
• Chen W, Lu C, Hong J. TRIM15 Exerts Anti-Tumor Effects Through Suppressing Cancer Cell Invasion in Gastric Adenocarcinoma. Med Sci Monit. 2018; 24:8033–8041. doi:10.12659/MSM.911142.
   PubMed Web of Science ®Google Scholar