Advanced search
Publication Cover
Journal of Investigative Surgery Volume 34, 2021 - Issue 8
Submit an article Journal homepage
931
Views
4
CrossRef citations to date
0
Altmetric
Commentary

New Horizons of Knowledge in Intervertebral Disc Disease

Silvia Ravallia Department of Biomedical and Biotechnological Sciences, Anatomy, Histology and Movement Sciences Section, School of Medicine, University of Catania, Catania, ItalyORCID Iconhttps://orcid.org/0000-0003-3358-1086
ORCID Icon &
Giuseppe Musumecia Department of Biomedical and Biotechnological Sciences, Anatomy, Histology and Movement Sciences Section, School of Medicine, University of Catania, Catania, Italy;b Research Center on Motor Activities (CRAM), University of Catania, Catania, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-8260-8890
ORCID Icon
Pages 912-913 | Published online: 10 Feb 2020

References

  • Adams MA, Roughley PJ. What is intervertebral disc degeneration, and what causes it? Spine (Phila PA 1976). 2006;31(18):2151–2161. doi:10.1097/01.brs.0000231761.73859.2c.
  • Ravindra VM, Senglaub SS, Rattani A, et al. Degenerative lumbar spine disease: Estimating global incidence and worldwide volume. Global Spine J. 2018;8(8):784–794. doi:10.1177/2192568218770769.
  • Zhao L, Manchikanti L, Kaye AD, et al. Treatment of discogenic low back pain: current treatment strategies and future options—a literature review. Curr Pain Headache Rep. 2019;23(11):86. doi:10.1007/s11916-019-0821-x.
  • Shen J, Xu S, Zhou H, et al. IL-1β induces apoptosis and autophagy via mitochondria pathway in human degenerative nucleus pulposus cells. Sci Rep. 2017;7(1):41067. doi:10.1038/srep41067.
  • Bai X, Guo X, Zhang F, et al. Resveratrol combined with 17β-estradiol prevents IL-1β induced apoptosis in human nucleus pulposus via the PI3K/AKT/mTOR and PI3K/AKT/GSK-3β pathway. J Invest Surg. 2021;34(8):904–911. doi:10.1080/08941939.2019.1705941.
  • Jiang Y, Xie Z, Yu J, et al. Resveratrol inhibits IL-1β-mediated nucleus pulposus cell apoptosis through regulating the PI3K/Akt pathway. Biosci Rep. 2019;39(3):pii: BSR20190043. doi:10.1042/BSR20190043.
  • Li X, Lin F, Wu Y, et al. Resveratrol attenuates inflammation environment-induced nucleus pulposus cell senescence in vitro. Biosci Rep. 2019;39(5):pii: BSR20190126. doi:10.1042/BSR20190126.
  • Gao XW, Su XT, Lu ZH, et al. 17β-estradiol prevents extracellular matrix degradation by downregulating MMP3 expression via PI3K/Akt/FOXO3 pathway. Spine (Phila PA 1976). 2019. doi:10.1097/BRS.0000000000003263.
  • Wang Y. Postmenopausal Chinese women show accelerated lumbar disc degeneration compared with Chinese men. J Orthop Translat. 2015;3(4):205–211. doi:10.1016/j.jot.2015.09.001.
  • Jin LY, Song XX, Li XF. The role of estrogen in intervertebral disc degeneration. Steroids. 2020;154:108549.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.