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Inhalation Toxicology
International Forum for Respiratory Research
Volume 12, 2000 - Issue sup1: Proceedings of the Third Colloquium on Particulate Air Pollution and Human Health: Part 1
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Peer-Reviewed Articles

Methodology For Delivery and Kinetics of Clearance of Insoluble Particles from Sublobar Lung Segments

W. M. FosterDepartment of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland, USACorrespondence[email protected]
,
K. MacriDepartment of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland, USA
,
S. McCullochDepartment of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland, USA
,
T. MyersDepartment of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland, USA
&
A. N. FreedDepartment of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland, USA
Pages 99-105 | Published online: 22 Feb 2016

References

  • Amundsson, T., and Kilburn, K. H. 1970. Mucociliary clearance rates at various levels in dog lungs. Am. Rev. Respir. Dis. 102:388–397.
  • Forbes, A. R., and Gamsu, G. 1979. Mucociliary clearance in the canine lung during and after general anesthesia. Anesthesiology 50:26–29.
  • Foster, W. M., and Freed, A. N. 1999. Regional clearance of solute from peripheral airway epithelia: recovery after sublobar exposure to ozone. J. Appl. Physiol. 86:641–646.
  • King, M., Engel, L. A., and Macklem, P. T. 1979. Effect of pentobarbital anesthesia on rheology and transport of canine tracheal mucus. J. Appl. Physiol. 46:504–509.
  • Lay, J. C. Berry, C. R., Kim, C. S., and Bennett, W. D. 1995. Retention of insoluble particles after local intrabronchial deposition in dogs. J. Appl. Physiol. 79:1921–1929.
  • Snipes, M. B., Spoo, J. W., Müggenburg, B. A., Nijkula, K. J., Hoover, M. D., Griffith, W. C., and Guilmette, R. A. 1996. Evaluation of the clearance of particles deposited on the conducting airways of beagle dogs. J. Aerosol Med. 9:477–499.
  • Svartengren, M., Anderson, M., Bylin, G., Philipson, K., and Camner, P. 1990. Regional deposition of 3.6 µm particles in subjects with mild to moderately severe asthma. J. Aerosol Med. 3:197–207.
  • Wolff, R. K., Tillquist, H., Müggenburg, B.A., Harkema, J. R., and Mauderly, J. L. 1989. Deposition and clearance of radiolabeled particles from small ciliated airways in beagle dogs. J. Aerosol Med. 2:261–270.

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