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Inhalation Toxicology
International Forum for Respiratory Research
Volume 14, 2002 - Issue 11
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Research Article

SMOKING CESSATION DECREASES THE NUMBER OF METAPLASTIC SECRETORY CELLS IN THE SMALL AIRWAYS OF THE GUINEA PIG

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Pages 1153-1159 | Published online: 01 Oct 2008

  • Aikawa, T., Shimura, S., Sasaki, H., Takishima, T., Yaegashi, H., and Takahashi, T. 1989. Morphometric analysis of intraluminal mucus in airways in chronic obstructive pulmonary disease. Am. Rev. Respir.Dis. 140:477-482.
  • Bernfeld, P., Homburger, F., Soto, E., and Pai, K. J. 1979. Cigarette smoke inhalation studies in inbred Syrian golden hamsters. JNCl 63:675-689.
  • Cosio, M., Ghezzo, H., Hogg, J. C., Corbin, R., Loveland, M., Dosman, J., and Macklem, P. T. 1977. The relations between structural changes in small airways and pulmonary function tests. N. Engl. J. Med. 298:1277-1281.
  • Cosio, M. G., Hale, K. A., and Niewoehner, D. E. 1980. Morphologic and morphometric effects of prolonged cigarette smoking on the small airways. Am. Rev. Respir. Dis. 122:265-271.
  • Hale, K. A., Ewing, S. L, Gosnell, B. A., and Niewoehner, D. E. 1984. Lung disease in long-term cigarette smokers with and without chronic air-flow obstruction. Am. Rev. Respir. Dis. 130:716-721.
  • Lamb, D., and Reid, L. 2001. Goblet cell increase in rat bronchial epithelium after exposure to cigarette and cigar tobacco smoke. Br. Med.J. 1:33-35.
  • Lumsden, A. B., McLean, A., and Lamb, D. 1984. Goblet and Clara cells of human distal airways: Evidence for smoking induced changes in their numbers. Thorax 394:844-849.
  • Macklem, P. T. 1998. The physiology of small airways. Am. Rev. Respir. Crit. Care Med. 157:S181-S183.
  • Matsuba, K., and Thurlbeck, W. M. 1973. Disease of the small airways in chronic bronchitis. Am. Rev. Respir. Dis. 107:552-558.
  • Mullen, J. B. M., Wright, J. L., Wiggs, B. R., Pare, P. D., and Hogg. J. C. 1987. Structure of central airways in current smokers and ex-smokers with and without mucus hypersecretion: Relationship to lung function. Thorax 42:843-848.
  • Niewoehner, D. E., Kleinerman, J., and Rice, D. B. 1974. Pathologic changes in the peripheral airways of young cigarette smokers. N. Engl. J. Med. 291:755-758.
  • Park, S. S., Kikkawa, Y., Goldring, I. P., DaIy, M. M., Zelefsky, M., Shim, C., Spierer, M., and Morita, T. 1977. An animal model of cigarette smoking in beagle dogs. Am. Rev. Respir. Dis. 115:971-979.
  • Saetta, M., Turato, G., Baraldo, S., Zanin, A., Braccioni, F., Mapp, C. E., Maestrelli, P., Cavallesco, G., Papi, A., and Fabbri, L. M. 2000. Goblet cell hyperplasia and epithelial inflammation in peripheral airways of smokers with both symptoms of chronic bronchitis and chronic airflow limitation. Am. Rev. Respir. Crit. Care Med. 161:1016-1021.
  • Takeyama, K., Jung, B., Shim, J. J., Burget, P. R., Dao-Pick, T., Ueki, I. F., Protin, A., Kroschel, P., and Nadel, J. A. 2001. Activation of epidermal growth factor receptors is responsible for mucin synthesis induced by cigarette smoke. Am. J. Physiol. 280:L165-L172.
  • Wilkinson, L. 1988. SYSTAT: The system for statistics. Evanston, IL: SYSTAT, Inc.
  • Wright, J. L., and Churg, A. 1990. Cigarette smoke causes physiologic and morphologic changes of emphysema in the guinea pig. Am. Rev. Respir. Dis. 142:1422-1428.
  • Wright, J. L, and Sun, J.-P. 1994. The effect of smoking cessation on pulmonary and cardiovascular function and structure. J. Appl. Physiol. 76:2163-2168.
  • Wright, J. L, Lawson, L. M., Pare, P. D., Wiggs, B. R., Kennedy, S., and Hogg, J. C. 1983. Morphology of peripheral airways in current smokers and ex- smokers. Am. Rev. Respir. Dis. 127:474-477.
  • Wright, J. L., Lawson, L M., Kennedy, S., Wiggs, B., and Hogg, J. C. 1984. The detection of small airways disease. Am. Rev. Respir. Dis. 129:989-994.
  • Wright, J. L., Ngai, T., and Churg, A. 1992. Effect of long-term exposure to cigarette smoke on the small airways of the guinea pig. Exp. Lung Res. 18:105-114.

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