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Inhalation Toxicology
International Forum for Respiratory Research
Volume 17, 2005 - Issue 4-5
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Research Article

Effects of Subchronic Exposures to Concentrated Ambient Particles in Mice: IX. Integral Assessment and Human Health Implications of Subchronic Exposures of Mice to CAPs

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Pages 255-261 | Received 30 Sep 2004, Accepted 08 Nov 2004, Published online: 06 Oct 2008

REFERENCES

  • Chen L. C., Hwang J.-S. Effects of subchronic exposures to concentrated ambient particles (CAPs) in mice: IV. Characterization of acute and chronic effects of ambient air fine particulate matter exposures on heart rate variability. Inhal. Toxicol. 2005; 17(4–5)209–216
  • Chen L. C., Nadziejko C. Effects of subchronic exposures to CAPs in mice: V. Exacerbation of aortic plaque development in hyperlipidemic mice after subchronic exposures to CAPs. Inhal. Toxicol. 2005; 17(4–5)217–224
  • Chen L. C., Schlesinger R. B. Response of the bronchial mucociliary clearance system in rabbits to inhaled sulfite and sulfuric acid aerosols. Toxicol. Appl. Pharmacol. 1983; 71: 123–131, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Devlin R. B., McDonnell W. F., Becker S., Madden M. C., McGee M. P., Perez R., Hatch G., House D. E., Koren H. S. Time-dependent changes of inflammatory mediators in the lungs of humans exposed to 0.4 ppm ozone for 2 hr: A comparison of mediators found in bronchoalveolar lavage fluid 1 and 18 hr after exposure. Toxicol. Appl. Pharmacol. 1996; 138: 176–185, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Fine J. M., Gordon T., Chen L. C., Kinney P., Falcone G., Sparer J., Beckett W. S. Characterization of clinical tolerance to inhaled zinc oxide in naive subjects and sheet metal workers. J. Occup. Environ. Med. 2000; 42: 1085–1091, [PUBMED], [INFOTRIEVE], [CSA]
  • Gong H. Jr., McManus M. S., Linn W. S. Attenuated response to repeated daily ozone exposures in asthmatic subjects. Arch. Environ. Health 1997; 52: 34–41, [PUBMED], [INFOTRIEVE], [CSA]
  • Gunnison A., Chen L. C. Effects of subchronic exposures to concentrated ambient particles in mice: VI. Measurement of gene expression in heart and lung tissue following exposure. Inhal. Toxicol. 2005; 17(4–5)225–233
  • Horvath S. M., Gliner J. A., Folinsbee L. J. Adaptation to ozone: Duration of effect. Am. Rev. Respir. Dis. 1981; 123: 496–499, [PUBMED], [INFOTRIEVE]
  • Hwang J.-S., Nadziejko C., Chen L. C. Effects of subchronic exposures to concentrated ambient particles in mice: III. Acute and chronic effects of CAPs on heart rate, heart rate variance, and body temperature. Inhal. Toxicol. 2005; 17(4–5)199–207
  • Iwasaki T., Takahashi M., Saito H., Arito H. Adaptation of extrapulmonary responses to ozone exposure in conscious rats. Ind. Health 1998; 36: 57–60, [PUBMED], [INFOTRIEVE]
  • Jorres R. A., Holz O., Zachgo W., Timm P., Koschyk S., Muller B., Grimminger F., Seeger W., Kelly F. J., Dunster C., Frischer T., Lubec G., Waschewski M., Niendorf A., Magnussen H. The effect of repeated ozone exposures on inflammatory markers in bronchoalveolar lavage fluid and mucosal biopsies. Am. J. Respir. Crit. Care Med. 2000; 161: 1855–1861, [PUBMED], [INFOTRIEVE], [CSA]
  • Lippmann M. Sulfur oxides: Acidic aerosols and SO2. Environmental toxicants: Human exposures and their health effects2nd, M. Lippmann. Wiley-Interscience, , New York 2000; pp. 771–809
  • Lippmann M., Schlesinger R. B. Interspecies comparisons of particle deposition and mucociliary clearance in tracheobronchial airways. J. Toxicol. Environ. Health 1984; 13: 441–469, [PUBMED], [INFOTRIEVE]
  • Lippmann M., Gordon T., Chen L. C. Effects of subchronic exposures to concentrated ambient particles (CAPs) in mice. I. Introduction, objectives and experimental plan. Inhal. Toxicol. 2005; 17(4–5)177–187
  • Maciejczyk P., Chen L. C. . Effects of subchronic exposures to concentrated ambient particles in mice: VIII. Source-related daily variations in In Vitro responses to CAPs. Inhal. Toxicol. 2005; 17(4–5)243–253
  • Maciejczyk P., Zhong M., Li Q., Xiong J., Nadziejko C., Chen L. C. . Effects of subchronic exposures to concentrated ambient particles (CAPs) in mice: II. The design of a CAPs exposure system for biometric telemetry monitoring. Inhal. Toxicol. 2005; 17(4–5)189–197
  • McKinney W. J., Jaskot R. H., Richards J. H., Costa D. L., Dreher K. L. Cytokine mediation of ozone-induced pulmonary adaptation. Am. J. Respir. Cell Mol. Biol. 1998; 18: 696–705, [PUBMED], [INFOTRIEVE], [CSA]
  • Oberdorster G., Sharp Z., Atudorei V., Elder A., Gelein R., Kreyling W., Cox C. Translocation of inhaled ultrafinne particles to the brain. Inhal. Toxicol. 2004; 16: 437–445, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]
  • Plopper C. G., Chu F. P., Haselton C. J., Peake J., Wu J., Pinkerton K. E. Dose dependent tolerance to ozone. I. Tracheobronchial epithelial reorganization in rats after 20 months' exposure. Am. J. Pathol. 1994; 144: 404–420, [PUBMED], [INFOTRIEVE]
  • Samet J. M., Zeger S. L., Dominici F., Curriero F., Coursac I., Dockery D. W., Schwartz J., Zanobetti A. L. The national morbidity, mortality, and air pollution study. Part II: Morbidity, mortality, and air pollution in the United States. Health Effects Institute, Research Report, Cambridge, MA 2000; 94
  • Superko H. R., Adams W. C., Daly P. W. Effects of ozone inhalation during exercise in selected patients with heart disease. Am. J. Med. 1984; 77: 463–470, [PUBMED], [INFOTRIEVE], [CROSSREF]
  • Air quality criteria for particulate matter. Research Triangle Park, NC: National Center for Environmental Assessment-RTP Office, Report EPA/600/P-99/002aF and EPA/600/p-99/0026F, October. U.S. Environmental Protection Agency., 2004
  • Veronesi B., Makwana O., Pooler M., Weir L., Chen L. C. Effects of subchronic exposures to concentrated ambient particles in mice: VII. Degeneration of dopaminergic neurons in ApoE−/−mice. Inhal. Toxicol. 2005; 17(4–5)235–241
  • Wesselkamper S. C., Chen L. C., Gordon T. Development of pulmonary tolerance in mice exposed to zinc oxide fumes. Toxicol. Sci. 2001; 60: 144–151, [PUBMED], [INFOTRIEVE], [CSA], [CROSSREF]

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