INFLAMMATION AND CELL DAMAGE INDUCED BY REPEATED EXPOSURE OF HUMANS TO OZONE

References

• Anderson, M. E. 1985. Determination of glutathione and glutathione disulfide in biological sam-ples. Methods EnzymoL 113:548–555.
   PubMed Web of Science ®Google Scholar
• Brummer, M. E. G., Schwartz, L. W., and McQuillen, N. K. 1977. A quantitative study to lung damage by scanning electron microscopy: Inflammatory cell response to high-ambient levels of ozone. Scan. Electron Microsc. 2:513–518.
   Google Scholar
• Bui, M. H., Sauty, A., Collet, F., and Leuenberger, P. 1992. Dietary vitamin C intake and con-centrations in the body fluids and cells of male smokers and nonsmokers.]. Nutr. 122:312–316.
   PubMed Web of Science ®Google Scholar
• Calderon-Garciduenas, L., Osorno-Velazquez, A., Bravo-Alvarez, H., Delgado-Chavez, R., and Barrios-Marquez, R. 1992. Histopathologic changes of the nasal mucosa in southwest Metropolitan Mexico City inhabitants. Am.]. Pathol. 140:225–232.
   Google Scholar
• Chatham, M. D., Eppler, J. H., Jr., Sauder, L. R., Green, D., and Kulle, T. J. 1987. Evaluation of the effects of vitamin C on ozone-induced bronchoconstriction in normal subjects. Ann. NY Acad. ScL 498:269–279.
   Google Scholar
• Detels, R., Rokaw, S. N., Coulson, A. H., Tashkin, D. P., Sayre, J. W., and Massey, F. J., Jr. 1979. The UCLA population studies of chronic obstructive respiratory disease. Part I, Methodology and comparison of lung function in areas of high and low pollution. Am.]. EpidemioL 109:33–58.
   Google Scholar
• Detels, R., Sayre, J. W., Coulson, A. H., Rokaw, S. N., Massey, F. J., Tashkin, D. P., and Wu, M. 1981. The UCLA population studies of chronic obstructive respiratory disease. Part 4, Respiratory effect of long-term exposure to photochemical oxidants, nitrogen dioxide, and sulfates on current and never smokers. Am. Rev. Respir. Dis. 124:673–680.
   PubMed Web of Science ®Google Scholar
• Devlin, R. B., McDonnell, W. F., Mann, R., Becker, S., House, D. E., Schreinemachers, D., and Koren, H. S. 1991. Exposure of humans to ambient levels of ozone for 6.6 hours causes cellular and biochemical changes in the lung. Am. J. Respir. Cell MoL BioL 4:72–81.
   PubMed Web of Science ®Google Scholar
• Devlin, R. B., McDonnell, W. F., Becker, S., Madden, M., McGee, M. P., Perez, R., Hatch, G., House, D. E., and Koren, H. S. 1996. Time-dependent changes of inflammatory mediators in the lungs of humans exposed to 0.4 ppm ozone for two hours: A comparison of media-tors found in bronchoalveolar lavage fluid 1 and 18 hours after exposure. ToxicoL Appl. PharmacoL 138:176–185.
   Google Scholar
• Evans, M. J., Dekker, N. P., Cabral-Anderson, L. J., and Shami, S. G. 1985. Morphological basis of tolerance to ozone. Exp. MoL PathoL 42:366–376.
   Google Scholar
• Folinsbee, L. J., Bedi, J. F., and Horvath, S. M. 1980. Respiratory responses in humans repeatedly exposed to low concentrations of ozone. Am. Rev. Respir. Dis. 121:431–439.
   PubMed Web of Science ®Google Scholar
• Folinsbee, L. J., Horstman, D. H., Kehrl, H. R., Harder, S., Abdul-Salaam, S., and Ives, P. J. 1994. Respiratory responses to repeated prolonged exposure to 0.12 ppm ozone. Am.]. Resp. Crit. Care Med. 149: 98–105.
   Google Scholar
• Foxcroft, W. J., and Adams, W. C. 1986. Effects of ozone exposure on four consecutive days on work performance and VO2max. J. Appl. PhysioL 61:960–966.
   PubMedGoogle Scholar
• Gimbrone, M. A., Jr., Obin, M. S., Brock, A. F., Luis, E. A., Hass, P. E., Hebert, C. A., Yip, Y. K., Leung, D. W., Lowe, D. G., Kohr, W. J. 1989. Endothelial interleukin-8: A novel inhibitor of leukocyte-endothelial interactions. Science 246:1601–1603.
   PubMed Web of Science ®Google Scholar
• Hackney, J. D., Linn, W. S., Mohler, J. G., and Collier, C. R. 1 977. Adaptation to short-term respiratory effects of ozone in men exposed repeatedly. J. Appl. PhysioL: Respir. Environ. Exercise PhysioL 43:82–85.
   Google Scholar
• Harkema, J. R., and Hotchkiss, J. A. 1993. Ozone- and endotoxin-induced mucous cell meta-plasias in rat airway epithelium: Novel animal models to study toxicant-induced epithelial transformation in airways. Toxicol. Lett. 68:251–263.
   PubMed Web of Science ®Google Scholar
• Hatch, G. E., Slade, R., Harris, L. P., McDonnell, W. F., Devlin, R. B., Koren, H. S., Costa, D. L., and McKee, J. 1 994. Ozone dose and effect in humans and rats. Am.]. Resp. Crit. Care Med. 150:676–683.
   Google Scholar
• Horvath, S. M., Gliner, J. A., and Folinsbee, L. J. 1981. Adaptation to ozone: Duration of effect. Am. Rev. Respir. Dis. 123:496–499.
   PubMed Web of Science ®Google Scholar
• Kinney, P. L., Nilsen, D. M., Lippmann, M., Brescia, M., Gordon, T., McGovern, T., El-Fawal, H., Devlin, R. B., and Rom, W. N. 1996. Biomarkers of lung inflammation in recre-ational joggers exposed to ozone. Am. Rev. Respir. Dis., in press.
   Google Scholar
• Kodavanti, U. P., Hatch, G. E., Starcher, B., Gin, S. N., Winsett, D., and Costa, D. L. 1995. Ozone induced pulmonary functional, pathological, and biochemical changes in normal and vitamin C-deficient guinea pigs. Fundam. AppL Toxicol. 24:154–164.
   PubMedGoogle Scholar
• Koren, H. S., Devlin, R. B., Graham, D. E., Mann, R., McGee, M. P., Horstman, D. H., Kozumbo, W. J., Becker, S., House, D. E., McDonnell, W. F., and Bromberg, P. A. 1989. Ozone-induced inflammation in the lower airways of human subjects. Am. Rev. Respir. Dis. 139:407–415.
   PubMed Web of Science ®Google Scholar
• Kutnink, M. A., Hawkes, W. C., Schaus, E. E., and Omaye, S. T. 1 987. An internal standard method for the unattended high-performance liquid chromatographic analysis of ascorbic acid in blood components. Anal. Biochem. 166:424–430.
   Google Scholar
• Ley, K., Baker, J. B., Cybulsky, M. I., Gimbrone, M. A., Jr., and Luscinskas, F. W. 1993. Intravenous interleukin-8 inhibits granulocyte emigration from rabbit mesenteric venules with-out altering t-selectin expression or leukocyte rolling.]. Immunol. 151: 6347–6357.
   Google Scholar
• Linn, W. S., Medway, D. A., Anzar, U. T., Valencia, L. M., Spier, C. E., Tsao, F. S., Fischer, D. A., and Hackney, J. D. 1982. Persistence of adaptation to ozone in volunteers exposed repeatedly for six weeks. Am. Rev. Respir. Dis. 125:491–495.
   PubMed Web of Science ®Google Scholar
• Linn, W. S., Avol, E. L., Shamoo, D. A., Peng, R. C., Valencia, L. M., Little, D. E., and Hackney, J. D. 1988. Repeated laboratory ozone exposures of volunteer Los Angeles resi-dents: An apparent seasonal variation in response. Toxicol. Indust. Health 4:505–520.
   PubMed Web of Science ®Google Scholar
• Matthay, M. A., Eschenbacher, W. L., and Goetzl, E. J. 1984. Elevated concentrations of leukotriene D4 in pulmonary edema fluid of patients with the adult respiratory distress syn-drome./ Clin. ImmunoL 4:479–483.
   Google Scholar
• Nikula, K. J., Wilson, D. W., Dungworth, D. L., and Plopper, C. G. 1988a. In vitro evidence of cellular adaptation to ozone toxicity in the rat trachea. ToxicoL AppL PharmacoL 93:394–402.
   PubMed Web of Science ®Google Scholar
• Nikula, K. J., Wilson, D. W., Gin, S. N., Plopper, C. G., and Dungworth, D. L. 1988b. The response of the rat tracheal epithelium to ozone exposure. Am.]. PathoL 131:373–384.
   PubMed Web of Science ®Google Scholar
• Pacht, E. R., Kaseki, H., Mohammed, J. R., Cornwell, D. G., and Davis, W. B. 1986. Deficiency of vitamin E in the alveolar fluid of cigarette smokers./ Clin. Invest. 77:789–796.
   Google Scholar
• Pick, E., and Keisari, Y. 1981. Superoxide anion and hydrogen peroxide production by chemically elicited peritoneal macrophages-Induction by multiple nonphagocytic stimuli. Cell. Immunol. 59:301–318.
   PubMed Web of Science ®Google Scholar
• Plopper, C. G., Chu, F. P., Haselton, C. J., Peake, J., Wu, J., and Pinkerton, K. E. 1994. Dose dependent tolerance to ozone. Am.]. PathoL 144:404–420.
   PubMed Web of Science ®Google Scholar
• Schwartz, L. W., Dungworth, D. L., Mustafa, M. G., Tarkington, B. K., and Tyler, W. S. 1976. Pulmonary responses of rats to ambient levels of ozone: effects of 7-day intermittent or continuous exposure. Lab. Invest. 34:565–578.
   PubMed Web of Science ®Google Scholar
• Seltzer, J., Bigby, B. G., Stulbarg, M., Holtzman, M. J., Nadel, J. A., Ueki, I. F., Leikauf, G. D., Goetzl, E. J., and Boushey, H. A. 1986. 03-induced change in bronchial reactivity to methacholine and airway inflammation in humans.]. AppL PhysioL 60:1321–1326.
   Google Scholar
• Slade, R., Highfill, J. W., and Hatch, G. E. 1989. Effects of depletion of ascorbic acid or non-protein sulfhydryls on the acute inhalation toxicity of nitrogen dioxide, ozone, and phogene. Inhal. ToxicoL 1:261–271.
   Google Scholar
• Slade, R., Crissman, K., Norwood, J., and Hatch, G. 1993. Comparison of antioxidant substances in bronchoalveolar lavage cells and fluid from humans, guinea pigs, and rats. Exp. Lung Res. 19:469–484.
   PubMed Web of Science ®Google Scholar
• Stevens, R. J., Sloan, M. F., Evans, M. J., and Freeman, G. 1974. Alveolar type 1 cell response to exposure to 0.5 ppm ozone for short periods. Exp. MoL PathoL 20:11–23.
   Google Scholar
• Tepper, J. S., Costa, D. L., Lehmann, J. R., Weber, M. F., and Hatch, G. E. 1989. Unattenuated structural and biochemical alterations in the rat lung during functional adaptation to ozone. Am. Rev. Respir. Dis. 140:493–501.
   PubMed Web of Science ®Google Scholar
• van Bree, L., Koren, H. S., Devlin, R. B., and Rombout, P. J. A. 1993. Recovery from attentuated inflammation in lower airways of rats following repeated exposure to ozone. Am. Rev. Respir. Dis. 147:A633.
   Google Scholar
• Vandewoude, M., Claeys, M., and De Leeuw, I. 1984. Determination of alpha-tocopherol in human plasma by high-performance liquid chromatography with electrochemical detection./ Chromatogr. 311:176–182.
   PubMed Web of Science ®Google Scholar
• Warren, D. L., Guth, D. J., and Last, J. A. 1986. Synergistic interaction of ozone and respirable aerosols on rat lungs. Toxicol. AppL PharmacoL 84:470–479.
   PubMed Web of Science ®Google Scholar
• Zwick, H., Popp, W., Wagner, C., Reiser, K., Schmoger, J., Bock, A., Herkner, K., and Radunsky, K. 1991. Effects of ozone on the respiratory health, allergic sensitization, and cel-lular immune system in children [published erratum appears in Am Rev. Respir. Dis. 19921. Am. Rev. Respir. Dis. 144:1075–1079.
   PubMed Web of Science ®Google Scholar