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Inhalation Toxicology
International Forum for Respiratory Research
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Research Article

PLATELET AGGREGATION IN CIGARETTE SMOKERS: A META-ANALYSIS

Pages 765-793 | Published online: 01 Oct 2008

References

  • Ahlsten, G., Ewald, U., and Tuvemo, T. 1986. Arachidonic-acid-induced platelet aggregation is increased in male but not female smokers. Prostaglandins Leukotrienes Med. 21:149–156.
  • Ardlie, N. G., Bell, L. K., and McGuiness, J. A. 1987. Synergistic potentiation by epinephrine of colla- gen or thrombin-induced calcium mobilization in human platelets. Thromb. Res. 46(4):519–526.
  • Ashby, P., Dalby, A. M., and Millar, J. H. D. 1965. Smoking and platelet stickiness. Lancet 2:158–159.
  • Bain, B. J. 1992. The haematological effects of smoking.]. Smoking-Related Dis. 3(2):99–108.
  • Barrow, S. E., Ward, P. S., Sleightholm, M. A., Ritter, J. M., and Dollery, C. T. 1989. Cigarette smoking: Profiles of thromboxane- and prostacyclin-derived products in human urine. Biochim. Biophys. Acta 993:121–127.
  • Benowitz, N. L. 1991. Nicotine and cardiovascular disease. In Effects of nicotine on biological systems, Advances in pharmacological sciences, eds. by F. Adlkofer and K. Thurau, pp. 579-596. Basel: Birkhauser Verlag.
  • Benowitz, N., Porchet, H., Sheiner, L., and Jacob, P. 1988. Nicotine absorption and cardiovascular ef-fects with smokeless tobacco use: Comparison with cigarettes and nicotine gum. Clin. PharmacoL Ther. 44:23–28.
  • Benowitz, N. L., Fitzgerald, G. A., Wilson, M., and Zhang, Q. 1993. Nicotine effects on eicosanoid formation and hemostatic function: Comparison of transdermal nicotine and cigarette smoking. J. Am. Coll. Card ioL 22:1159–1167.
  • Berglund, U., Wallentin, L., and von Schenk, H. 1988. Platelet function and plasma fibrinogen and their relations to gender, smoking habits, obesity and beta-blocker treatment in young survivors of myocardial infarction. Thromb. Haemostasis 60:21–24.
  • Beswick, A. D., Fehily, A. M., Sharp, D. S., Renaud, S., and Giddings, J. 1991. Long-term diet modifi-cation and platelet activity. J. Intern. Med. 229:511–515.
  • Bierenbaum, M. L., Fleischman, A. I., Stier, A., Somol, H., and Watson, P. A. 1978. Effect of cigarette smoking upon in vivo platelet function in man. Thromb. Res. 12:1051–1057.
  • Blache, D. 1995. Involvement of hydrogen and lipid peroxides in acute tobacco smoking-induced platelet hyperactivity. Am.]. Physiol. 268(Heart Circ. Physiol. 37):H679–H685.
  • Blache, D., Bouthillier, D., and Davignon, J. 1992. Acute influence of smoking on platelet behaviour, endothelium and plasma lipids and normalization by aspirin. Atherosclerosis 93:179–188.
  • Burghuber, O. C., Punzengruber, C., Sinzinger, H., Haber, P., and Si lberbauer, K. 1986. Platelet sensitivity to prostacyclin in smokers and non-smokers. Chest 90:34–38.
  • Bygdeman, S., and Johnsen, O. 1969. Studies on the effect of adrenergic blocking drugs on cate-cholamine induced platelet aggregation and uptake of noradrenaline and 5-hydroxytryptamine. Acta Physiol. Scand. 75(1/2):129–138.
  • Carlsson, I., and Wennmalm, A. 1983. Platelet aggregability in smoking and non-smoking subjects. Clin. Physiol. 3:565–571.
  • Chant, C., Fagan, S. C., Aurora, S. K., Gidal, B. E., and Joseph, R. 1997. Effects of aspirin on platelet aggregation in smokers and nonsmokers. Ann. Pharmacother. 31:290–293.
  • Chao, F. C., Tullis, J. L., Alper, C. A., Glynn, R. J., and Silbert, J. E. 1982. Alteration in plasma proteins and platelet functions with aging and cigarette smoking in healthy men. Thromb. Haemostasis 47:259–264.
  • Charo, I. F., Feinman, R. D., and Detwiler, T. C. 1977. Interrelations of platelet aggregation and secretion./ Clin. Invest. 60(4):866–873.
  • Chiang, V. L., Castleden, W. M., and Leahy, M. F. 1992. Detection of reversible platelet aggregates in the blood of smokers and ex-smokers with peripheral vascular disease. Med.]. Aust. 156:601–603.
  • Crooks, G., Copeland, S., and Johnston, G. D. 1988. Does cigarette smoking alter platelet aggrega-tion in women receiving the contraceptive pill? Ulster Med.]. 57:177–180.
  • Cryer, P. E., Haymond, M. W., Santiago, J. V., and Shah, S. D. 1976. Norepinephrine and epineph-rine release and adrenergic mediation of smoking-associated hemodynamic and metabolic events. N. Engl.]. Med. 295(11):573–577.
  • Davis, J. W., and Arnold, J. 1989. A comparison of the effects of chewing nicotine gum and smoking cigarettes on collagen-induced platelet aggregation. Clin. Res. 37:927A.
  • Davis, J. W., and Arnold, J. 1992. Time course of some effects of cigarette smoking on platelets.]. Intern. Med. 231:31–36.
  • Davis, J. W., and Davis, R. F. 1979. Acute effect of tobacco cigarette smoking on the platelet aggre-gate ratio. Am.]. Med. ScL 278:139–143.
  • Davis, J. W., and Davis, R. F. 1981. Prevention of cigarette smoking-induced platelet aggregate for-mation by aspirin. Arch. Intern. Med. 141:206–207.
  • Davis, R. F., and Davis, J. W. 1983. The effect of smoking on the stressed template bleeding time. Ann. Clin. Res. 15:131–133.
  • Davis, J. W., Shelton, L., Eigenburg, D. A., Hignite, C. E., and Watanabe, I. S. 1985. Effects of tobacco and non-tobacco cigarette smoking on endothelium and platelets. Clin. Pharmacol. Ther. 35:529–533.
  • Davis, J. W., Arnold, J., and Wiegmann, T. B. 1988. Cigarette smoking increases collagen-induced platelet aggregation of men with chronic renal failure. Clin. Res. 36:889A.
  • Davis, J. W., Hartman, C. R., Shelton, L., and Ruttinger, H. A. 1989. A trial of dipyridamole and aspirin in the prevention of smoking-induced changes in platelets and endothelium in men with coronary artery disease. Am.]. CardioL 63:1450–1454.
  • Davis, J. W., Arnold, J., and Wiegmann, T. 1993. Cigarette-smoking affects platelets and endothelium in chronic hemodialysis patients. Nephron 64:359–364.
  • Dotevall, A., Ungemark, C., Eriksson, E., Kutti, J., Wadenvik, H., and Wennmalm, A. 1992. Cigarette smoking increases thromboxane A2 formation without affecting platelet survival in young healthy females. Thromb. Haemostasis 68(5):583–588.
  • Feher, M. D., Rampling, M. W., Brown, J., Robinson, R., Richmond, W., Cholerton, S., Bain, B. J., and Sever, P. S. 1990. Acute changes in atherogenic and thrombogenic factors with cessation of smoking./ R. Soc. Med. 83(3):146–148.
  • Foo, L. C., Rosh idah, I., and Aimy, M. B. 1991. Platelets of habitual smokers have reduced suscepti-bility to aggregating agent. Thromb. Haemostasis 65:317–319.
  • Gleerup, G., and Winther, K. 1996. Smoking further increases platelet activity in patients with mild hypertension. Eur. J. Clin. Invest. 26:49–52.
  • Grignani, G., Gamba, G., and Ascari, E. 1977. Cigarette-smoking effect on platelet function. Thromb. Haemostasis 37:423–428.
  • Hawkins, R. I. 1972. Smoking, platelets and thrombosis. Nature 236:450–452.
  • Hillbom, M., Muuronen, A., Löwbeer, C., Anggard, E., Beving, H., and Kangasaho, M. 1985. Platelet thromboxane formation and bleeding time is influenced by ethanol withdrawal but not by ciga-rette smoking. Thromb. Haemostasis 53:419–422.
  • Holbrook, J. H., Grundy, S. M., Hennekens, C. H., Kannel, W. B., and Strong, J. P. 1984. Cigarette smoking and cardiovascular diseases. Circulation 70(6):1114A-1117A.
  • Hollister, A. S., Fitzgerald, G. A., Nadeau, J. H., and Robertson, D. 1983. Acute reduction in human platelet alpha 2-adrenoreceptor affinity for agonist by endogenous and exogenous cate-cholamines. J. Clin. Invest. 72(4):1498–1505.
  • Hung, J., Lam, J. Y. T., Lacoste, L., and Letchacovski, G. 1995. Cigarette smoking acutely increases platelet thrombus formation in patients with coronary artery disease taking aspirin. Circulation 92:2432–2436.
  • Imaizumi, T., Satoh, K., Yoshida, H., Kawamura, Y., Hiramoto, M., Koyanagi, M., Takamatsu, S., and Takamatsu, M. 1990. Activity of platelet-activating factor (PAF) acetylhydrolase in plasma from healthy habitual cigarette smokers. Heart Vessels 5:81–86.
  • Jaschonek, K., Weisenberger, H., Tidow, S., Daiss, W., Renn, W., and Ostendorf, P. 1986. Platelet prostacyclin binding in smokers.]. Lab. Clin. Med. 108:88–95.
  • Jones, C. R., Giembcyz, M., Hamilton, C. A., Rodger, I. W., Whyte, K., Deighton, N., Elliott, H. L., and Reid, J. L. 1986. Desensitization of platelet alpha 2-adrenoceptcrs after short term infusions of adrenoceptoragonist in man. Clin. ScL 70(2):147–153.
  • Kampman, M. T., and Hornstra, G. 1988. No acute effect of cigarette smoking on bleeding time of habitual smokers. Thromb. Res. 52:287–294.
  • Lanza, F., and Cazenave, J. P. 1985. Studies of alpha 2-adrenergic receptors of intact and functional washed human platelets by binding of 3H-dihydroergocryptine and 3H-yohimbine-Correlation of 3H-yohimbine binding with the potentiation by adrenaline of ADP-induced aggregation. Thromb. Haemostasis 54(2):402–408.
  • Lassila, R. 1989. The platelet 2-adrenoceptor and prostacyclin sensitivity are not altered by cigarette smoking-A study of monozygotic twin pairs discordant for smoking. Thromb. Res. 54:339–348.
  • Lassila, R., and Laustiola, K. E. 1988. Physical exercise provokes platelet desensitization in men who smoke cigarettes-Involvement of sympathoadrenergic mechanisms-A study of monozygotic twin pairs discordant for smoking. Thromb. Res. 51:145–155.
  • Lassila, R., and Laustiola, K. E. 1992. Cigarette smoking and platelet-vessel wall interactions. Prostaglandins Leukotrienes Essential Fatty Acids 46:81–86.
  • Lassila, R., Seyberth, H. W., Haapanen, A., Schweer, H., Koskenvuo, M., and Laustiola, K. E. 1988. Vasoactive and atherogenic effects of cigarette smoking: a study of monozygotic twins discor-dant for smoking. Br. Med.]. 297:955–957.
  • László, E., Káldi, N., and Kovács, L. 1983. Alterations in plasma proteins and platelet functions with aging and cigarette smoking in healthy men. Thromb. Haemostasis 49:150.
  • Levine, P. H. 1973. An acute effect of cigarette smoking on platelet function: A possible link between smoking and arterial thrombosis. Circulation 48:619–623.
  • Madsen, H., and Dyerberg, J. 1984. Cigarette smoking and its effect on the platelet-vessel wall inter-action. Scand. J. Clin. Lab. Invest. 44:203–206.
  • Marasini, B., Biondi, M. L., Barbesti, S., Zatta, G., and Agostoni, A. 1986. Cigarette smoking and platelet function. Thromb. Res. 44:85–94.
  • McGill, H. C. 1988. The cardiovascular pathology of smoking. Am. Heart]. 115:250–257.
  • Meade, T. W., Vickers, M. V., Thompson, S. G., Stirling, Y., Haines, A. P., and Miller, G. J. 1985. Epidemiological characteristics of platelet aggregability. Br. Med.]. 290:428–432.
  • Meade, T. W., Imeson, J., and Stirling, Y. 1987. Effects of changes in smoking and other characteris-tics on clotting factors and the risk of ischaemic heart disease. Lancet2(8566):986–988.
  • Mileikowsky, G. N., Nadler, J. L., Huey, F., Francis, R., and Roy, S. 1988. Evidence that smoking alters prostacyclin formation and platelet aggregation in women who use oral contraceptives. Am.]. Obstet. Gynecol. 159:1547–1552.
  • Mills, D. C., and Roberts, G. C. 1967. Effects of adrenaline on human blood platelets.]. Physiol. (Lond.) 193(2):443–453.
  • Motulsky, H. J., Shattil, S. J., Ferry, N., Rozansky, D., and Inset, P. A. 1986. Desensitization of epi-nephrine-initiated platelet aggregation does not alter binding to the alpha-2-adrenergic receptor or receptor coupling to adenylate cyclase. MoL PharmacoL 29(1):1–6.
  • Murray, J. J., Nowak, J., Oates, J. A., and FitzGerald, G. A. 1985. Platelet function during chronic smoking and withdrawal in man. Clin. Res. 33:350A.
  • Nadler, J. L., Velasco, J. S., and Horton, R. 1983. Cigarette smoking inhibits prostacycl in formation. Lancet1(8336):1248–1250.
  • Nowak, J., Murray, J. J., Oates, J. A., and FitzGerald, G. A. 1987. Biochemical evidence of a chronic abnormality in platelet and vascular function in healthy individuals who smoke cigarettes. Circulation 76:6–14.
  • O'Brien, J. R. 1965. Effects of adenosine diphosphate and adrenaline on mean platelet shape. Nature (Lond.) 207:306–307.
  • O'Brien, J. R., Etherington, M., Jamieson, S., and Klaber, M. R. 1973. Stressed template bleeding-time and other platelet-function tests in myocardial infarction. Lancet March 31:694–696.
  • Ungemark, C., and Wennmalm, A. 1991. Cigarette smoking and urinary excretion of markers for platelet/vessel wall interaction in healthy women. Clin. ScL 81:11–15.
  • Ungemark, C., and Wennmalm, A. 1996. Smoke-derived nitric oxide and vascular prostacycl in are unable to counteract the platelet effect of increased thromboxane formation in healthy female smokers. Clin. Physiol. 16:301–315.
  • Ungemark, C., Benthin, G., Granstrom, E. F., Persson, L., Winell, S., and Wennmalm, A. 1992. Tobacco use and urinary excretion of thromboxane A2 and prostacycl in metabolites in women stratified by age. Circulation 86:1495–1500.
  • Ungemark, C., Ciabattoni, G., and Wennmalm, A. 1993. Excretion of thromboxane metabolites in healthy women after cessation of smoking. Arteriosclerosis Thromb. 13:777–782.
  • Renaud, S., Blache, D., Dumont, E., Thevenon, C., and Wissendanger, T. 1984. Platelet function after cigarette smoking in relation to nicotine and carbon monoxide. Clin. Pharmacol. Ther. 36:389–395.
  • Ring, T., Kristensen, S. D., Jensen, P. N., Mounts-Andersen, T., Madsen, H., and Dyerberg, J. 1983. Cigarette smoking shortens the bleeding time. Thromb. Res. 32: 531–536.
  • Rival, J., Riddle, J. M., and Stein, P. D. 1987. Effects of chronic smoking on platelet function. Thromb. Res. 45:75–85.
  • Roberts, W. C. 1989. Atherosclerotic risk factors-Are there ten or is there only one? Am.]. CardioL 64(8):552–554.
  • Rosenthal, R. 1991. Meta-analytic procedures for social research, rev. ed. Newbury Park, CA: Sage. Schmidt, K. J., and Rasmussen, J. W. 1984. Acute platelet activation induced by smoking: in vivo and ex vivo studies in humans. Thromb. Haemostasis 51:279–282.
  • Sharp, D. S., Benowitz, N. L., Bath, P. M. W., Martin, J. F., Beswick, A. D., and Elwood, P. C. 1995. Cigarette smoking sensitizes and desensitizes impedance-measured ADP-induced platelet aggre-gation in whole blood. Thromb. Haemostasis 74(2):730–735.
  • Siess, W., Lorenz, R., Roth, P., and Weber, P. C. 1982. Plasma catecholamines, platelet aggregation and associated thromboxane formation after physical exercise, smoking or norepinephrine infu-sion. Circulation 66(1):44–48.
  • Snedecor, G. W., and Cochran, W. G. 1980. Statistical methods, 7th ed. Ames, IA: Iowa State University Press.
  • Sturm, M. J., Strophair, J. M., Kendrew, P. J., Vandongen, R., Beilin, L. J., and Taylor, R. R. 1989. Whole blood aggregation and plasma lyso-PAF related to smoking and atherosclerosis. Clin. Exp. PharmacoL Physiol. 16:597–605.
  • Subar, A. F., Harlan, L. C., and Mattson, M. E. 1990. Food and nutrient intake differences between smokers and non-smokers in the US. Am.]. Public Health 80(11):1323–1329.
  • Taylor, R. G. 1987. Smoking and the leucocyte count. Eur. J. Resp. Dis. 71:65–68.
  • Taylor, R. R., Sturm, M., Vandongen, R., Strophair, J., and Beilin, L. J. 1987. Whole blood platelet aggregation is not affected by cigarette smoking but is sex-related. Clin. Exp. Pharmacol. Physiol. 14:665–671.
  • Terres, W., Becker, P., and Rosenberg, A. 1994. Changes in cardiovascular risk profile during the cessation of smoking. Am.]. Med. 97:242–249.
  • Thomas, D. P. 1967. Effect of catecholamines on platelet aggregation caused by thrombin. Nature 215(98):298–299.
  • Trap-Jensen, J., Carlsen, J. E., Svendsen, T. L., and Christensen, N. J. 1979. Cardiovascular and adren-ergic effects of cigarette smoking during immediate non-selective and selective beta adrenore-ceptor blockade in humans. Eur. J. Clin. Invest. 9: 181–183.
  • Uedelhoven, W. M., Razel, A., Meese, C. O., and Weber, P. C. 1991. Smoking alters thromboxane metabolism in man. Biochim. Biophys. Acta 1081:197–201.
  • Uyama, O., Matsui, Y., Shimizu, S., Michishita, H., and Sugita, M. 1994. Risk factors for carotid ath-erosclerosis and platelet activation. Jpn. Circ. J. 58:409–415.
  • Vicari, A. M., Margonato, A., Macagni, A., Luoni, R., and Seveso, M. P. 1988. Effects of acute smok-ing on the hemostatic systems in humans. Clin. CardioL 11:538–540.
  • Wennmalm, A., Benthin, G., Granstrom, E. F., Persson, L., Petersson, A.-S., and Winell, S. 1991. Relation between tobacco use and urinary excretion of thromboxane A2 and prostacyclin metabolites in young men. Circulation 83:1698–1704.
  • Wennmalm, A., Benthin, G., Granstrom, E. F., Persson, L., and Winell, S. 1993. Maintained hyperex-cretion of thromboxane A2 metabolite in healthy young cigarette smokers: Results from a prospective study in randomly sampled males with stable smoking habits. Clin. Physiol. 13:257–264.
  • Westfall, T. C., Cipolloni, P. B., and Edmundowiez, A. C. 1966. Influence of propromolol on haemo-dynamic changes and plasma catecholamine levels following cigarette smoking and nicotine. Proc. Soc. Exp. Biol. Med. 123:174–178.
  • Whichelow, M. J., Golding, J. F., and Treasure, F. P. 1988. Comparison of some dietary habits of smokers and non-smokers. Br.]. Addict. 83:295–304.
  • Wu, K. K., and Hoak, J. C. 1974. A new method for the quantitative detection of platelet aggregates in patients with arterial insufficiency. Lancer2(7886):924–926.

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