Combined effects of TGFβ1 and BMP2 in serum-free chondrogenic differentiation of mesenchymal stem cells induced hyaline-like cartilage formation

References

• Brittberg M, Lindahl A, Nilsson A, Ohlsson C, Isaksson O, Peterson L. Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 1994; 331(14)889–895
   PubMed Web of Science ®Google Scholar
• Brown AN, Kim BS, Alsberg E, Mooney DJ. Combining chondrocytes and smooth muscle cells to engineer hybrid soft tissue constructs. Tissue Eng 2000; 6(4)297–305
   PubMedGoogle Scholar
• Buckwalter JA. Articular cartilage injuries. Clin Orthop Relat Res 2002; 402: 21–37, Review
   PubMed Web of Science ®Google Scholar
• Carlberg AL, Pucci B, Rallapalli R, Tuan RS, Hall DJ. Efficient chondrogenic differentiation of mesenchymal cells in micromass culture by retroviral gene transfer of BMP-2. Differentiation. 2001; 67(4–5)128–138
   Google Scholar
• Colter DC, Sekiya I, Prockop DJ. Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells. Proc Natl Acad Sci 2001; 98(14)7841–7845
   PubMed Web of Science ®Google Scholar
• Conget PA, Minguell JJ. Phenotypical and functional properties of human bone marrow mesenchymal progenitor cells. J Cell Physiol 1999; 181(1)67–73
   PubMed Web of Science ®Google Scholar
• Dozin B, Malpeli M, Comardella L, Cancedda R, Pietrangelo A. Response of young, aged and osteoarthritic human articular chondrocytes to inflammatory cytokines: molecular and cellular aspects. Matrix Biol 2002; 21(5)449–459
   Google Scholar
• Frenkel SR, Clancy RM, Ricci JL, et al. Effects of nitric oxide on chondrocyte migration, adhesion, and cytoskeletal assembly. Arthritis Rheum 1996; 39: 1905–1912
   PubMedGoogle Scholar
• Hardingham T, Tew S, Murdoch A. Tissue engineering: chondrocytes and cartilage. Arthritis Res 2002; 4(Suppl. 3)S63–S68
   Google Scholar
• Huang CY, Hagar KL, Frost LE, Sun Y, Cheung HS. Effects of cyclic compressive loading on chondrogenesis of rabbit bone-marrow derived mesenchymal stem cells. Stem Cells 2004; 22(3)313–323
   PubMed Web of Science ®Google Scholar
• Iwasaki M, Nakata K, Nakahara H, Nakase T, Kimura T, Kimata K, Caplan AI, Ono K. Transforming growth factor-beta 1 stimulates chondrogenesis and inhibits osteogenesis in high density culture of periosteum – derived cells. Endocrinology 1993; 132(4)1603–1608
   Google Scholar
• Johnstone B, Hering TM, Caplan AI, Goldberg VM, Yoo JU. In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells. Exp Cell Res 1998; 238(1)265–272
   PubMed Web of Science ®Google Scholar
• Kim YJ, Sah RL, Doong JY, Grodzinsky AJ. Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal Biochem. 1988; 174(1)168–176
   PubMed Web of Science ®Google Scholar
• Kozo Akino, Takao Mineta, Masashi Fukui, Tohru Fujii, Sadanori Akita. Bone morphogenetic protein-2 regulates proliferation of human mesenchymal stem cells. Wound Rep Reg 2003; 11(5)354–360
   Google Scholar
• Kulyk WM, Rodgers BJ, Greer K, Kosher RA, et al. Promotion of embryonic chick limb cartilage differentiation by transforming growth factor beta. Dev Biol 1989; 135(2)424–430
   Google Scholar
• Luyten FP, Yu YM, Yanagishita M, Vukicevic S, Hammonds RG, Reddi AH. Natural bovine osteogenin and recombinant human bone morphogenetic protein-2B are equipotent in the maintenance of proteoglycans in bovine articular cartilage explant cultures. J Biol Chem 1992; 267: 3691–3695
   PubMed Web of Science ®Google Scholar
• Lyons KM, Pelton RW, Hogan BL. Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A). Development 1990; 109(4)833–844
   Google Scholar
• Mankin H, Mow V, Buckwalter J. Form and function of articular cartilage. Orthopaedic basic science, S Simon. American Academy of Orthopaedic Surgeons, Rosemont, IL 1994; 443–470
   Google Scholar
• Martin JA, Buckwalter JA. Aging, articular cartilage chondrocyte senescence and osteoarthritis. Biogerontology 2002; 3: 257–264
   PubMed Web of Science ®Google Scholar
• Martin I, Jakob M, Schafer D, Dick W, Spagnoli G, Heberer M. Quantitative analysis of gene expression in human articular cartilage from normal and osteoarthritic joints. Osteoarthr Cartil 2001; 9(2)112–118
   Google Scholar
• Mitchell N, Shepard N. The resurfacing of adult rabbit articular cartilage by multiple perforations through the subchondral bone. J Bone Joint Surg Am 1976; 58: 230–233
   PubMed Web of Science ®Google Scholar
• Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR. Multilineage potential of adult human mesenchymal stem cells. Science 1999; 284: 143–147
   PubMed Web of Science ®Google Scholar
• Schmitt B, Ringe J, Haupl T, Notter M, Manz R, Burmester GR, Sittinger M, Kaps C. BMP2 initiates chondrogenic lineage development of adult human mesenchymal stem cells in high-density culture. Differentiation 2003; 71(9–10)567–577
   Google Scholar
• Wakitani S, Imoto K, Yamamoto T, Saito M, Murata N, Yoneda M. Human autologous culture expanded bone marrow mesenchymal cell transplantation for repair of cartilage defects in osteoarthritic knees. Osteoarthr Cartil 2002; 10(3)199–206
   PubMed Web of Science ®Google Scholar