Sublingual delivery of chondroitin sulfate conjugated tapentadol loaded nanovesicles for the treatment of osteoarthritis

References

• Bagari, R., et al., 2011. Chondroitin sulfate functionalized liposomes for solid tumor targeting. Journal of drug targeting, 19 (4), 251–257.
   PubMed Web of Science ®Google Scholar
• Bhatia, D., Bejarano, T., and Novo, M., 2013. Current interventions in the management of knee osteoarthritis. Journal of pharmacy and bioallied sciences, 5 (1), 30–38.
   PubMedGoogle Scholar
• Bind, A.K., Gnanarajan, G., and Kothiyal, P., 2017. A review: sublingual route for systemic drug delivery. International journal of drug research and technology, 3, 5.
   Google Scholar
• Bishnoi, M., et al., 2014. Aceclofenac-loaded chondroitin sulfate conjugated SLNs for effective management of osteoarthritis. Journal of drug targeting, 22 (9), 805–812.
   PubMed Web of Science ®Google Scholar
• Bishnoi, M., et al., 2016. Chondroitin sulfate: a focus on osteoarthritis. Glycoconjugate journal, 33 (5), 693–705.,
   PubMed Web of Science ®Google Scholar
• Briuglia, M.L., et al., 2015. Influence of cholesterol on liposome stability and on in vitro drug release. Drug delivery and translational research, 5 (3), 231–242.,
   PubMed Web of Science ®Google Scholar
• Chang, E.J., Choi, E.J., and Kim, K.H., 2016. Tapentadol: can it kill two birds with one stone without breaking windows? The Korean journal of pain, 29 (3), 153.
   PubMed Web of Science ®Google Scholar
• Chibowski, E., and Szcześ, A., 2016. Zeta potential and surface charge of DPPC and DOPC liposomes in the presence of PLC enzyme. Adsorption, 22 (4–6), 755–765.
   Web of Science ®Google Scholar
• D’Souza, S., 2014. A review of in vitro drug release test methods for nano-sized dosage forms. Advances in pharmaceutics, 2014, 1–12.
   Google Scholar
• Dali, M.M., et al., 2006. A rabbit model for sublingual drug delivery: comparison with human pharmacokinetic studies of propranolol, verapamil and captopril. Journal of pharmaceutical sciences., 95 (1), 37–44.,
   PubMed Web of Science ®Google Scholar
• Eddy, N.B., Leimbach, D.J.J.O.P., and Therapeutics, E., 1953. Synthetic analgesics. II. Dithienylbutenyl-and dithienylbutylamines. The journal of pharmacology and experimental therapeutics, 107 (3), 385–393.
   PubMed Web of Science ®Google Scholar
• Faria, J., et al., 2017. Effective analgesic doses of tramadol or tapentadol induce brain, lung and heart toxicity in Wistar rats. Toxicology, 385, 38–47.
   PubMed Web of Science ®Google Scholar
• Franchi, S., et al., 2017. Effect of tapentadol on splenic cytokine production in mice. Anesthesia & analgesia, 124 (3), 986–995.,
   PubMed Web of Science ®Google Scholar
• Fry, D.W., White, J.C., and Goldman, I.D. 1978. Rapid separation of low molecular weight solutes from liposomes without dilution. Analytical biochemistry, 90, 809–815.
   PubMed Web of Science ®Google Scholar
• Fujimoto, T., et al., 2001. CD44 binds a chondroitin sulfate proteoglycan, aggrecan. International immunology, 13 (3), 359–366.
   PubMed Web of Science ®Google Scholar
• Grimaldi, N., et al., 2016. Lipid-based nanovesicles for nanomedicine. Chemical society reviews, 45 (23), 6520–6545.
   PubMed Web of Science ®Google Scholar
• Haywood, A.R., Hathway, G.J., and Chapman, V., 2018. Differential contributions of peripheral and central mechanisms to pain in a rodent model of osteoarthritis. Scientific reports, 8 (1), 7122.
   PubMedGoogle Scholar
• Isacchi, B., et al., 2017. Liposomal formulation to increase stability and prolong antineuropathic activity of verbascoside. Planta medica, 83, 412–419.
   PubMed Web of Science ®Google Scholar
• Jain, A., and Jain, S.K., 2016a. In vitro release kinetics model fitting of liposomes: an insight. Chemistry and physics of lipids, 201, 28–40.
   Web of Science ®Google Scholar
• Jain, A., and Jain, S.K., 2016b. Multipronged, strategic delivery of paclitaxel-topotecan using engineered liposomes to ovarian cancer. Drug development and industrial pharmacy, 42 (1), 136–149.
   PubMed Web of Science ®Google Scholar
• Jain, A., and Jain, S. K., 2017. Chapter 9. Application potential of engineered liposomes in tumor targeting. In: A.M. Grumezescu, ed. Multifunctional systems for combined delivery, biosensing and diagnostics. Amsterdam, The Netherlands: Elsevier, 171–191.
   Google Scholar
• Jain, A., and Jain, S.K., 2018. Stimuli-responsive smart liposomes in cancer targeting. Current drug targets, 19 (3), 259–270.
   PubMed Web of Science ®Google Scholar
• Jain, A., et al., 2013. Dual drug delivery using “smart” liposomes for triggered release of anticancer agents. Journal of nanoparticle research, 15 (7), 1772.
   Web of Science ®Google Scholar
• Jain, A., Hurkat, P., and Jain, S.K., 2019. Development of liposomes using formulation by design: basics to recent advances. Chemistry and physics of lipids, 224, 104764.
   PubMed Web of Science ®Google Scholar
• Jain, A., et al., 2018. Nanocarrier based advances in drug delivery to tumor: an overview. Current drug targets, 19 (13), 1498–1518.
   PubMed Web of Science ®Google Scholar
• Jain, A. J., and Sanjay, K., 2016. Liposomes in cancer therapy. In: J. Carlos, ed. Nanocarrier systems for drug delivery. New York: Nova Science Publishers, 1–42.
   Google Scholar
• Jain, S. K., and Jain, A., 2016c. Ligand mediated drug targeted liposomes. In: A. Samad, S. Beg, I. Nazish, eds. Liposomal delivery systems: advances and challenges. London, UK: Future Medicine Ltd.
   Google Scholar
• Jain, A., and Jain, S. K., 2016d. Chapter 1. Liposomes in cancer therapy. In: J. Carlos, ed. Nanocarrier systems for drug delivery. New York: Nova Science Publishers, 1–42. https://www.researchgate.net/profile/Ankit_Jain44/publication/309534086_Liposomes_in_Cancer_Therapy/links/5cba0abba6fdcc1d49a0ff74/Liposomes-in-Cancer-Therapy.pdf#page=11
   Google Scholar
• Khalil, R.M., et al., 2017. Enhancement of lomefloxacin Hcl ocular efficacy via niosomal encapsulation: In vitro characterization and in vivo evaluation. Journal of liposome research, 27 (4), 312–323.,
   PubMed Web of Science ®Google Scholar
• Khwaldia, K., 2019. Chondroitin and glucosamine. Nonvitamin and nonmineral nutritional supplements. Amsterdam, The Netherlands: Elsevier, 27–35.
   Google Scholar
• Kim, N., et al., 2016. A prospective evaluation of opioid utilization after upper-extremity surgical procedures: identifying consumption patterns and determining prescribing guidelines. The journal of bone and joint surgery, 98 (20), e89.
   PubMed Web of Science ®Google Scholar
• Kraft, J.C., et al., 2014. Emerging research and clinical development trends of liposome and lipid nanoparticle drug delivery systems. Journal of pharmaceutical sciences, 103 (1), 29–52.
   PubMed Web of Science ®Google Scholar
• Kumari, A., et al., 2018. Eudragit S100 coated microsponges for colon targeting of prednisolone. Drug development and industrial pharmacy, 44 (6), 902–913.
   PubMed Web of Science ®Google Scholar
• Langford, R.M., et al., 2016. Is tapentadol different from classical opioids? A review of the evidence. British journal of pain, 10, 217–221.
   PubMed Web of Science ®Google Scholar
• Lee, S.-Y., et al., 2018. The therapeutic effect of STAT3 signaling-suppressed MSC on pain and articular cartilage damage in a rat model of monosodium iodoacetate-induced osteoarthritis. Frontiers in immunology, 9, 2881.
   PubMed Web of Science ®Google Scholar
• Lin, W.J., and Lee, W.C., 2018. Polysaccharide-modified nanoparticles with intelligent CD44 receptor targeting ability for gene delivery. International journal of nanomedicine, 13, 3989–4002.
   PubMed Web of Science ®Google Scholar
• Liu, D.-Z., et al., 2000. Microcalorimetric and shear studies on the effects of cholesterol on the physical stability of lipid vesicles. Colloids & surfaces A, 172, 57–67.
   Web of Science ®Google Scholar
• Liu, P., et al., 2019. Preparation, characterisation and in vitro and in vivo evaluation of CD44-targeted chondroitin sulfate-conjugated doxorubicin PLGA nanoparticles. Carbohydrate polymers, 213, 17–26.
   PubMed Web of Science ®Google Scholar
• Liu, Y.-S., et al., 2014. Preparation of chondroitin sulfate-g-poly (ε-caprolactone) copolymers as a CD44-targeted vehicle for enhanced intracellular uptake. Molecular pharmaceutics, 11 (4), 1164–1175.,
   PubMed Web of Science ®Google Scholar
• Maheshwari, R.G., et al., 2012. Ethosomes and ultradeformable liposomes for transdermal delivery of clotrimazole: a comparative assessment. Saudi pharmaceutical journal, 20 (2), 161–170.,
   PubMed Web of Science ®Google Scholar
• Mishra, R. K., et al., 2019. Efficient nanocarriers for drug-delivery systems: types and fabrication. Nanocarriers for drug delivery. Amsterdam, The Netherlands: Elsevier, 1–41.
   Google Scholar
• Montell, E., Pelletier, J.-P., and Martel-Pelletier, J., 2019. Chondroitin sulfate pharmacological activity from four different sources in human osteoarthritic cartilage. The FASEB journal, 33, lb383–lb383.
   Google Scholar
• Mura, P., et al., 2018. A preliminary study for the development and optimization by experimental design of an in vitro method for prediction of drug buccal absorption. International journal of pharmaceutics, 547 (1–2), 530–536.
   PubMed Web of Science ®Google Scholar
• Panchagnula, R., et al., 2001. Transdermal delivery of naloxone: effect of water, propylene glycol, ethanol and their binary combinations on permeation through rat skin. International journal of pharmaceutics, 219, 95–105.
   PubMed Web of Science ®Google Scholar
• Patil, G.B., and Surana, SJ. 2017. Bio-fabrication and statistical optimization of polysorbate 80 coated chitosan nanoparticles of tapentadol hydrochloride for central antinociceptive effect: in vitro–in vivo studies. Artificial cells, nanomedicine and biotechnology, 45, 505–514.
   PubMed Web of Science ®Google Scholar
• Pentak, D., et al., 2016. Methotrexate and cytarabine—loaded nanocarriers for multidrug cancer therapy. Spectroscopic study. Molecules, 21 (12), 1689.
   Web of Science ®Google Scholar
• Pitcher, T., Sousa-Valente, J., and Malcangio, M. 2016. The monoiodoacetate model of osteoarthritis pain in the mouse. Journal of visualized experiments. 111, e53746.
   Google Scholar
• Prajapati, S.K., et al., 2019. Hyaluronic acid conjugated multi-walled carbon nanotubes for colon cancer targeting. International journal of biological macromolecules, 123, 691–703.
   PubMed Web of Science ®Google Scholar
• Putri, D.C.A., Dwiastuti, R., Marchaban, M., and Nugroho, A.K. 2017. Optimization of mixing temperature and sonication duration in liposome preparation. Journal of pharmaceutical sciences & community, 14, 79–85.
   Google Scholar
• Ramaswamy, S., Chang, S., and Mehta, V.J.A., 2015. Tapentadol – the evidence so far. Anesthesia, 70, 518–522.
   PubMed Web of Science ®Google Scholar
• Ravar, F., et al., 2016. Hyaluronic acid-coated liposomes for targeted delivery of paclitaxel, in-vitro characterization and in-vivo evaluation. Journal of controlled release, 229, 10–22.
   PubMed Web of Science ®Google Scholar
• Restaino, O.F., et al., 2019. European chondroitin sulfate and glucosamine food supplements: a systematic quality and quantity assessment compared to pharmaceuticals. Carbohydrate polymers, 222, 114984.
   PubMed Web of Science ®Google Scholar
• Romualdi, P., et al., 2019. Pharmacological rationale for tapentadol therapy: a review of new evidence. Journal of pain research, 12, 1513–1520.
   PubMed Web of Science ®Google Scholar
• Saraf, S., et al., 2016. Topotecan liposomes: a visit from a molecular to a therapeutic platform. Critical reviews in therapeutic drug carrier systems, 33 (5), 401–432.
   PubMed Web of Science ®Google Scholar
• Schiraldi, C., Cimini, D., and De Rosa, M., 2010. Production of chondroitin sulfate and chondroitin. Applied microbiology and biotechnology, 87 (4), 1209–1220.
   PubMed Web of Science ®Google Scholar
• Singh, D.R., et al., 2013. Tapentadol hydrochloride: a novel analgesic. Saudi journal of anaesthesia, 7 (3), 322.
   PubMedGoogle Scholar
• Singh, Y., et al., 2017. Nanoemulsion: concepts, development and applications in drug delivery. Journal of controlled release, 252, 28–49.
   PubMed Web of Science ®Google Scholar
• Sobue, Y., et al., 2019. Inhibition of CD44 intracellular domain production suppresses bovine articular chondrocyte de-differentiation induced by excessive mechanical stress loading. Scientific reports, 9 (1), 10.
   PubMedGoogle Scholar
• Sorensen, E.N., Weisman, G., and Vidaver, G.A., 1977. A sephadex column procedure for measuring uptake and loss of low molecular weight solutes from small, lipid-rich vesicles. Analytical biochemistry, 82 (2), 376–384.
   PubMed Web of Science ®Google Scholar
• Sydykov, B., et al., 2018. Membrane permeabilization of phosphatidylcholine liposomes induced by cryopreservation and vitrification solutions. Biochimica et Biophysica Acta (BBA) biomembranes, 1860 (2), 467–474.
   PubMed Web of Science ®Google Scholar
• Terenzi, R., et al., 2017. FRI0070 Angiotensin II type 2 receptor (AT2R) is overexpressed in rheumatoid arthritis and osteoarthritis synovium and increases steadily with inflammatory stimuli: a potential new target for pain and anti-inflammatory therapies. Rheumatoid arthritis, 76, 504.
   Google Scholar
• Thudium, C.S., et al., 2019. Protein biomarkers associated with pain mechanisms in osteoarthritis. Journal of proteomics, 190, 55–66.
   PubMed Web of Science ®Google Scholar
• Turdean, S.G., et al., 2017. Histopathological evaluation and expression of the pluripotent mesenchymal stem cell-like markers CD105 and CD44 in the synovial membrane of patients with primary versus secondary hip osteoarthritis. Journal of investigative medicine, 65 (2), 363–369.
   PubMed Web of Science ®Google Scholar
• Verma, A., et al., 2019. Systematic optimization of cationic surface engineered mucoadhesive vesicles employing Design of Experiment (DoE): a preclinical investigation. International journal of biological macromolecules, 133, 1142–1155.
   PubMed Web of Science ®Google Scholar
• Vinothini, K., and Rajan, M., 2019. Mechanism for the nano-based drug delivery system. Characterization and biology of nanomaterials for drug delivery. Amsterdam, The Netherlands: Elsevier, 219–263.
   Google Scholar
• Zhu, H., et al., 2013. Nanovesicles system for rapid-onset sublingual delivery containing sodium tanshinone IIA sulfonate: in vitro and in vivo evaluation. Journal of pharmaceutical science, 102, 2332–2340.
   PubMed Web of Science ®Google Scholar
• Zylberberg, C., and Matosevic, S.J.D.D., 2016. Pharmaceutical liposomal drug delivery: a review of new delivery systems and a look at the regulatory landscape. Drug delivery, 23, 3319–3329.
   PubMed Web of Science ®Google Scholar