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Baylor University Medical Center Proceedings
The peer-reviewed journal of Baylor Scott & White Health
Volume 35, 2022 - Issue 5
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Case Studies

Breakthrough COVID-19 infection inducing acute epiglottitis in an immunized host

Matthew Mitchella College of Medicine, Texas A&M Health Science Center, College Station, TexasCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-3358-6135
, BSORCID Icon,
Madison Burasb Department of Otolaryngology, Baylor Scott & White Medical Center – Temple, Temple, TexasORCID Iconhttps://orcid.org/0000-0002-2479-3688
, MDORCID Icon,
Mollie Shutterc Department of Emergency Medicine, Baylor Scott & White Medical Center – Temple, Temple, Texas
, MD &
J. Scott Wietersc Department of Emergency Medicine, Baylor Scott & White Medical Center – Temple, Temple, TexasORCID Iconhttps://orcid.org/0000-0002-4707-1581
, MDORCID Icon
Pages 658-660 | Received 05 Apr 2022, Accepted 16 May 2022, Published online: 06 Jun 2022

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  • Emberey J, Velala SS, Marshall B, et al. Acute epiglottitis due to COVID-19 infection. Eur J Case Rep Intern Med. 2021;8(3):002280. doi:10.12890/2021_002280.
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  • Bertram S, Heurich A, Lavender H, et al. Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts. PLoS One. 2012;7(4):e35876. doi:10.1371/journal.pone.0035876.
  • Zhang H, Rostami MR, Leopold PL, et al. Expression of the SARS-CoV-2 ACE2 receptor in the human airway epithelium. Am J Respir Crit Care Med. 2020;202(2):219–229. doi:10.1164/rccm.202003-0541OC.
  • Chu YC, Ho MP. Re: acute epiglottitis in a COVID-19 positive patient. Am J Emerg Med. 2022;55:230.e1. doi:10.1016/j.ajem.2022.01.035.
  • Pham LL, Bourayou R, Maghraoui-Slim V, Koné-Paut I. Laryngitis, epiglottitis and pharyngitis. Infect Dis. 2017;229–235.e1. doi:10.1016/B978-0-7020-6285-8.00025-3.
  • Fondaw A, Arshad M, Batool S, et al. COVID-19 infection presenting with acute epiglottitis. J Surg Case Rep. 2020;2020(9):rjaa280. doi:10.1093/jscr/rjaa280.
  • Lee J, Loh J, Lee TS. Double thumb sign in a case of epiglottitis. Radiol Case Rep. 2021;16(7):1810–1814. doi:10.1016/j.radcr.2021.04.007.
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