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Editorial: Celebrating the 2015 Nobel Prize to Prof. Satoshi Omura

Celebrating Dr. Satoshi Ōmura, the recipient of the 2015 Nobel Prize in Physiology or Medicine

Agricultural chemistry, ivermectin, and MDR1

References

  • The Nobel Assembly at Karolinska Institutet. Press Release, October 5 2015.
  • Suzuki U, Shimamura T. An active factor in rice bran (in Japanese). Tokyo Kagaku Kaishi. 1911;32: 4–16.
  • Ōmura S. Nobel Lecture “A splendid gift from the earth: the origins and impact of the avermectins”. December 7, 2015.
  • Chen C-J, Chin JE, Ueda K, et al. Internal dupilication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistance human cells. Cell. 1986;47:381–389.10.1016/0092-8674(86)90595-7
  • Ueda K, Cardarelli C, Gottesman MM, et al. Expression of a full-length cDNA for the human “MDR1” gene confers resistance to colchicine, doxorubicin, and vinblastine. Proc Natl Acad Sci USA. 1987;84:3004–3008.10.1073/pnas.84.9.3004
  • UEDA K. ABC proteins protect human body and maintain optimal health. Biosci Biotechnol Biochem. 2011;75:401–409.10.1271/bbb.100816
  • Schinkel AH, Smit JJM, van Tellingen O, et al. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell. 1994;77:491–502.10.1016/0092-8674(94)90212-7

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