Allyl isothiocyanate increases carbohydrate oxidation through enhancing insulin secretion by TRPV1

References

• Caterina MJ, Schumacher MA, Tominaga M, et al. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature. 1997;389:816–824.
   PubMed Web of Science ®Google Scholar
• Tominaga M, Caterina MJ, Malmberg AB, et al. The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron. 1998;21:531–543.10.1016/S0896-6273(00)80564-4
   PubMed Web of Science ®Google Scholar
• Story GM, Peier AM, Reeve AJ, et al. ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell. 2003;112:819–829.10.1016/S0092-8674(03)00158-2
   PubMed Web of Science ®Google Scholar
• McNamara FN, Randall A, Gunthorpe MJ. Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1). Br J Pharmacol. 2005;144:781–790.10.1038/sj.bjp.0706040
   PubMed Web of Science ®Google Scholar
• Macpherson LJ, Geierstanger BH, Viswanath V, et al. The pungency of garlic: activation of TRPA1 and TRPV1 in response to allicin. Curr Biol. 2005;15:929–934.10.1016/j.cub.2005.04.018
   PubMed Web of Science ®Google Scholar
• Motter AL, Ahern GP. TRPV1-null mice are protected from diet-induced obesity. FEBS Lett. 2008;582:2257–2262.10.1016/j.febslet.2008.05.021
   PubMed Web of Science ®Google Scholar
• Mori N, Kawabata F, Matsumura S, et al. Intragastric administration of allyl isothiocyanate increases carbohydrate oxidation via TRPV1 but not TRPA1 in mice. Am J Physiol Regul Integr Comp Physiol. 2011;300:R1494–R1505.10.1152/ajpregu.00645.2009
   PubMed Web of Science ®Google Scholar
• Kang JH, Goto T, Han IS, et al. Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet. Obesity (Silver Spring). 2010;18:780–787.10.1038/oby.2009.301
   PubMed Web of Science ®Google Scholar
• Tanaka H, Shimaya A, Kiso T, et al. Enhanced insulin secretion and sensitization in diabetic mice on chronic treatment with a transient receptor potential vanilloid 1 antagonist. Life Sci. 2011;88:559–563.10.1016/j.lfs.2011.01.016
   PubMed Web of Science ®Google Scholar
• Suri A, Szallasi A. The emerging role of TRPV1 in diabetes and obesity. Trends Pharmacol Sci. 2008;29:29–36.10.1016/j.tips.2007.10.016
   PubMed Web of Science ®Google Scholar
• Jordt SE, Bautista DM, Chuang HH, et al. Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature. 2004;427:260–265.10.1038/nature02282
   PubMed Web of Science ®Google Scholar
• Everaerts W, Gees M, Alpizar YA, et al. The capsaicin receptor TRPV1 is a crucial mediator of the noxious effects of mustard oil. Curr Biol. 2011;21:316–321.10.1016/j.cub.2011.01.031
   PubMed Web of Science ®Google Scholar
• Mori N, Kurata M, Yamazaki H, et al. Intragastric administration of allyl isothiocyanate reduces hyperglycemia in intraperitoneal glucose tolerance test (IPGTT) by enhancing blood glucose consumption in mice. J Nutr Sci Vitaminol (Tokyo). 2013;59:56–63.10.3177/jnsv.59.56
   PubMed Web of Science ®Google Scholar
• Akiba Y, Kato S, Katsube K, et al. Transient receptor potential vanilloid subfamily 1 expressed in pancreatic islet beta cells modulates insulin secretion in rats. Biochem Biophys Res Commun. 2004;321:219–225.10.1016/j.bbrc.2004.06.149
   PubMed Web of Science ®Google Scholar
• Caterina MJ, Leffler A, Malmberg AB, et al. Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science. 2000;288:306–313.10.1126/science.288.5464.306
   PubMed Web of Science ®Google Scholar
• Bautista DM, Jordt SE, Nikai T, et al. TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell. 2006;124:1269–1282.10.1016/j.cell.2006.02.023
   PubMed Web of Science ®Google Scholar
• Zawalich WS, Yamazaki H, Zawalich KC. Biphasic insulin secretion from freshly isolated or cultured, perifused rodent islets: comparative studies with rats and mice. Metabolism. 2008;57:30–39.10.1016/j.metabol.2007.07.020
   PubMed Web of Science ®Google Scholar
• Albano JD, Ekins RP, Maritz G, et al. A sensitive, precise radioimmunoassay of serum insulin relying on charcoal separation of bound and free hormone moieties. Acta Endocrinol (Copenh). 1972;70:487–509.
   PubMedGoogle Scholar
• Brusewitz G, Cameron BD, Chasseaud LF, et al. The metabolism of benzyl isothiocyanate and its cysteine conjugate. Biochem J. 1977;162:99–107.10.1042/bj1620099
   PubMed Web of Science ®Google Scholar
• Frayn KN. Calculation of substrate oxidation rates in vivo from gaseous exchange. J Appl Physiol. 1983;55:628–634.
   PubMed Web of Science ®Google Scholar
• Borghoff SJ, Birnbaum LS. Age-related changes in the metabolism and excretion of allyl isothiocyanate. A model compound for glutathione conjugation. Drug Metab Dispos. 1986;14:417–422.
   PubMed Web of Science ®Google Scholar
• Bollard M, Stribbling S, Mitchell S, et al. The disposition of allyl isothiocyanate in the rat and mouse. Food Chem Toxicol. 1997;35:933–943.10.1016/S0278-6915(97)00103-8
   PubMed Web of Science ®Google Scholar
• Ioannou YM, Burka LT, Matthews HB. Allyl isothiocyanate: comparative disposition in rats and mice. Toxicol Appl Pharmacol. 1984;75:173–181.10.1016/0041-008X(84)90199-6
   PubMed Web of Science ®Google Scholar
• Gram DX, Ahrén B, Nagy I, et al. Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes. Eur J Neurosci. 2007;25:213–223.10.1111/j.1460-9568.2006.05261.x
   PubMed Web of Science ®Google Scholar
• Razavi R, Chan Y, Afifiyan FN, et al. TRPV1+ sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes. Cell. 2006;127:1123–1135.10.1016/j.cell.2006.10.038
   PubMed Web of Science ®Google Scholar
• Diaz-Garcia CM, Morales-Lazaro SL, Sanchez-Soto C, et al. Role for the TRPV1 channel in insulin secretion from pancreatic beta cells. J Membr Biol. 2014;247:479–491.10.1007/s00232-014-9658-8
   PubMed Web of Science ®Google Scholar
• Malaisse WJ, Malaisse-Lagae F. The role of cyclic AMP in insulin release. Experientia. 1984;40:1068–1075.10.1007/BF01971453
   PubMedGoogle Scholar
• Sharp GW. The adenylate cyclase-cyclic AMP system in islets of langerhans and its role in the control of insulin release. Diabetologia. 1979;16:287–296.10.1007/BF01223617
   PubMed Web of Science ®Google Scholar
• Malenczyk K, Girach F, Szodorai E, et al. A TRPV1-to-secretagogin regulatory axis controls pancreatic beta-cell survival by modulating protein turnover. EMBO J. 2017;36:2107–2125.10.15252/embj.201695347
   PubMed Web of Science ®Google Scholar
• Roy MW, Lee KC, Jones MS, et al. Neural control of pancreatic insulin and somatostatin secretion. Endocrinology. 1984;115:770–775.10.1210/endo-115-2-770
   PubMed Web of Science ®Google Scholar
• Woods SC, Porte D Jr. Neural control of the endocrine pancreas. Physiol Rev. 1974;54:596–619.
   PubMed Web of Science ®Google Scholar
• Kurose T, Seino Y, Nishi S, et al. Mechanism of sympathetic neural regulation of insulin, somatostatin, and glucagon secretion. Am J Physiol. 1990;258:E220–227.
   PubMedGoogle Scholar
• Nishi S, Seino Y, Ishida H, et al. Vagal regulation of insulin, glucagon, and somatostatin secretion in vitro in the rat. J Clin Invest. 1987;79:1191–1196.10.1172/JCI112936
   PubMed Web of Science ®Google Scholar
• Andersen DK, Elahi D, Brown JC, et al. Oral glucose augmentation of insulin secretion. Interactions of gastric inhibitory polypeptide with ambient glucose and insulin levels. J Clin Invest. 1978;62:152–161.10.1172/JCI109100
   PubMed Web of Science ®Google Scholar
• Dupre J, Ross SA, Watson D, et al. Stimulation of insulin secretion by gastric inhibitory polypeptide in man. J Clin Endocrinol Metab. 1973;37:826–828.10.1210/jcem-37-5-826
   PubMed Web of Science ®Google Scholar
• Zawalich WS. Synergistic impact of cholecystokinin and gastric inhibitory polypeptide on the regulation of insulin secretion. Metabolism. 1988;37:778–781.10.1016/0026-0495(88)90014-5
   PubMed Web of Science ®Google Scholar
• Zawalich WS, Diaz VA. Prior cholecystokinin exposure sensitizes islets of Langerhans to glucose stimulation. Diabetes. 1987;36:118–122.10.2337/diab.36.1.118
   PubMed Web of Science ®Google Scholar
• Ahren B. Autonomic regulation of islet hormone secretion–implications for health and disease. Diabetologia. 2000;43:393–410.
   PubMed Web of Science ®Google Scholar
• Riera CE, Huising MO, Follett P, et al. TRPV1 pain receptors regulate longevity and metabolism by neuropeptide signaling. Cell. 2014;157:1023–1036.10.1016/j.cell.2014.03.051
   PubMed Web of Science ®Google Scholar
• Kyle Palmer RK, Lunn CA. TRP channels as targets for therapeutic intervention in obesity: focus on TRPV1 and TRPM5. Curr Top Med Chem. 2013;13:247–257.10.2174/15680266113139990089
   PubMed Web of Science ®Google Scholar