408
Views
5
CrossRef citations to date
0
Altmetric
Biochemistry & Molecular Biology

Immunosuppressive effect of a non-proteinogenic amino acid from Streptomyces through inhibiting allogeneic T cell proliferation

, , , , , , , , , , & show all
Pages 1111-1116 | Received 10 Dec 2018, Accepted 22 Feb 2019, Published online: 22 Mar 2019

References

  • Hasebe F, Matsuda K, Shiraishi T, et al. Amino-group carrier-protein-mediated secondary metabolite biosynthesis in Streptomyces. Nat Chem Biol. 2016;12:967–972.
  • Horie A, Tomita T, Saiki A, et al. Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus. Nat Chem Biol. 2009;5:673–679.
  • Ouchi T, Tomita T, Horie A, et al. Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus. Nat Chem Biol. 2013;9:277–283.
  • Fujita T, Inoue K, Yamamoto S, et al. Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite. J Antibiot (Tokyo). 1994;47:208–215.
  • Miyake Y, Kozutsumi Y, Nakamura S, et al. Serine palmitoyltransferase is the primary target of a sphingosine-like immunosuppressant, ISP-1/myriocin. Biochem Biophys Res Commun. 1995;211:396–403.
  • Hannun YA, Obeid LM. Principles of bioactive lipid signalling: lessons from sphingolipids. Nat Rev Mol Cell Biol. 2008;9:139–150.
  • Brinkmann V, Billich A, Baumruker T, et al. Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis. Nat Rev Drug Discov. 2010;9:883–897.
  • Wei SH, Rosen H, Matheu MP, et al. Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses. Nat Immunol. 2005;6:1228–1235.
  • Graler MH, Goetzl EJ. The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors. FASEB J. 2004;18:551–553.
  • Matloubian M, Lo CG, Cinamon G, et al. Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1. Nature. 2004;427:355–360.
  • Kluepfel D, Bagli J, Baker H, et al. Myriocin, a new antifungal antibiotic from Myriococcum albomyces. J Antibiot (Tokyo). 1972;25:109–115.
  • Aragozzini F, Craveri R, Scolastico C, et al. Isolation and structure determination of a new antifungal alpha-hydroxymhthyl-alpha-amino acid. Tetrahedron. 1972;28:5493.
  • Kitamura N, Yokoyama H, Yashiro T, et al. Role of PU.1 in MHC class II expression through transcriptional regulation of class II transactivator pI in dendritic cells. J Allergy Clin Immunol. 2012;129(814–824):e816.
  • Nagaoka M, Yashiro T, Uchida Y, et al. The orphan nuclear receptor NR4A3 is involved in the function of dendritic cells. J Immunol. 2017;199:2958–2967.
  • Yashiro T, Hara M, Ogawa H, et al. Critical role of transcription factor PU.1 in the function of the OX40L/TNFSF4 promoter in dendritic cells. Sci Rep. 2016;6:34825.
  • Nakamura S, Kozutsumi Y, Sun Y, et al. Dual roles of sphingolipids in signaling of the escape from and onset of apoptosis in a mouse cytotoxic T-cell line, CTLL-2. J Biol Chem. 1996;271:1255–1257.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.