384
Views
1
CrossRef citations to date
0
Altmetric
Award Review

Control of cellular organization and its coordination with the cell cycle

Pages 869-875 | Received 16 Dec 2019, Accepted 09 Jan 2020, Published online: 27 Jan 2020

References

  • Hayles J, Nurse P. A journey into space. Nat Rev Mol Cell Biol. 2001;2:647–656.
  • Neumann FR, Nurse P. Nuclear size control in fission yeast. J Cell Biol. 2007;179:593–600.
  • Mitchison JM. Physiological and cytological methods for Schizosaccharomyces pombe. In: Prescott DM, editor. Methods in cell physiology. New York, NY: Academic Press. 1970. p. 131–165.
  • Marks J, Hagan I, Hymas JS. Growth polarity and cytokinesis in fission yeast: the role of the cytoskeleton. J Cell Sci. 1986;5:229–241.
  • Mitchison JM, Nurse P. Growth in cell length in the fission yeast Schizosaccharomyces pombe. J Cell Sci. 1985;75:357–376.
  • Nelson B, Kurischoko C, Horecka J, et al. RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis. Mol Biol Cell. 2003;14:3782–3803.
  • Weiss EL. Mitotic exit and separation of mother and daughter cells. Genetics. 2012;192:1165–1202.
  • Hansen CG, Moroishi T, Guan KL. YAP and TAZ: a nexus for Hippo signaling and beyond. Trends Cell Biol. 2015;25:499–513.
  • Kanai M, Kume K, Miyahara K, et al. Fission yeast MO25 protein is localized at SPB and septum and is essential for cell morphogenesis. EMBO J. 2005;24:3012–3025.
  • Mendoza M, Redemann S, Brunner D. The fission yeast MO25 protein functions in polar growth and cell separation. Eur J Cell Biol. 2005;84:915–926.
  • Miyamoto H, Matsushiro A, Nozaki M. Molecular cloning of a novel mRNA sequence expressed in cleavage stage mouse embryo. Mol Reprod Dev. 1993;34:1–7.
  • Nozaki M, Onishi Y, Togashi S, et al. Molecular characterization of the Drosophila Mo25 gene, which is conserved among Drosophila, mouse and yeast. DNA Cell Biol. 1996;15:505–509.
  • Karos M, Fischer R. Molecular characterization of HymA, an evolutionarily highly conserved and highly expressed protein of Aspergillus nidulans. Mol Gen Genet. 1999;260:510–521.
  • Dan I, Watanabe NM, Kusumi A. The Ste20 group kinases as regulators of MAP kinase cascades. Trends Cell Biol. 2001;11:220–230.
  • Leonhard K, Nurse P. Ste20/GCK kinase Nak1/Orb3 polarizes the actin cytoskeleton in fission yeast during the cell cycle. J Cell Sci. 2005;118:1033–1044.
  • Kume K, Kubota S, Koyano T, et al. Fission yeast leucine-rich repeat protein Lrp1 is essential for cell morphogenesis as a component of the morphogenesis Orb6 network (MOR). Biosci Biotechnol Biochem. 2013;77:1086–1091.
  • Gupta S, Mana-Capelli S, McLean JR, et al. Identification of SIN pathway targets reveals mechanisms of crosstalk between NDR kinase pathways. Curr Biol. 2013;23:333–338.
  • Hirata D, Kishimoto N, Suda M, et al. Fission yeast Mor2/Cps12, a protein similar to Drosophila Furry, is essential for cell morphogenesis and its mutation induces Wee1-dependent G2 delay. EMBO J. 2002;21:4863–4874.
  • Cong J, Geng W, He B, et al. The furry gene of Drosophila is important for maintaining the integrity of cellular extensions during morphogenesis. Development. 2001;128:2793–2802.
  • Verde F, Wiley DJ, Nurse P. Fission yeast orb6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle. Proc Natl Acad Sci USA. 1998;95:7526–7531.
  • Hergovich A, Stegert MR, Schimiz D, et al. NDR kinases regulate essential cell processes from yeast to humans. Nat Rev Mol Cell Biol. 2006;7:253–264.
  • Tamaskovic R, Bichsel SJ, Hemmings BA. NDR family of AGC kinases - essential regulators of the cell cycle and morphogenesis. FEBS Lett. 2003;546:73–80.
  • Hou MC, Wiley DJ, Verde F, et al. Mob2p interacts with the protein kinase Orb6p to promote coordination of cell polarity with cell cycle progression. J Cell Sci. 2003;116:125–135.
  • Ray S, Kume K, Gupta S, et al. The mitosis-to-interphase transition is coordinated by cross talk between the SIN and MOR pathways in Schizosaccharomyces pombe. J Cell Biol. 2010;190:793–804.
  • Hotz M, Barral Y. The mitotic exit network: new turns on old pathways. Trends Cell Biol. 2014;24:145–152.
  • Kume K, Goshima T, Miyahara K, et al. A method for Pmo25-associated kinase assay in fission yeast: the activity is dependent on two GC kinases Nak1 and Sid1. Biosci Biotechnol Biochem. 2007;71:615–617.
  • Nunez I, Rodriguez PM, Wiley DJ, et al. Spatial control of translation repression and polarized growth by conserved NDR kinase Orb6 and RNA-binding protein Sts5. eLife. 2016;5:e14216.
  • Das M, Nunez I, Rodriguez M, et al. Phosphorylation-dependent inhibition of Cdc42 GEF Gef1 by 14-3-3 protein Rad24 spatially regulates Cdc42 GTPase activity and oscillatory dynamics during cell morphogenesis. Mol Biol Cell. 2015;26:3520–3532.
  • Tay YD, Leda M, Spanos C, et al. Fission yeast NDR/LATS kinase Orb6 regulates exocytosis via phosphorylation of the exocyst complex. Cell Rep. 2019;26:1654–1667.
  • Martin SG, Chang F. New end take off: regulating cell polarity during the fission yeast cell cycle. Cell Cycle. 2005;4:1046–1049.
  • Huisman SM, Brunner D. Cell polarity in fission yeast: a matter of confining, positioning, and switching growth zones. Semin Cell Dev Biol. 2011;22:799–805.
  • Kume K, Koyano T, Kanai M, et al. Calcineurin ensures a link between the DNA replication checkpoint and microtubule-dependent polarized growth. Nat Cell Biol. 2011;13:234–242.
  • Rhind N, Russell P. Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways. J Cell Sci. 2000;113:3889–3896.
  • Lindsay HD, Griffiths DJF, Edwards RJ, et al. S-phase specific activation of Cds1 kinase defines a subpathway of the checkpoint response in Schizosaccharomyces pombe. Genes Dev. 1998;12(3):382–395.
  • Klee CB, Ren H, Wang X. Regulation of the calmodulin-stimulated protein phosphatase, calcineurin. J Biol Chem. 1998;273:13367–13370.
  • Yoshida T, Toda T, Yanagida M. A calcineurin-like gene ppb1+ in fission yeast: mutant defects in cytokinesis, cell polarity, mating and spindle pole body positioning. J Cell Sci. 1994;107:1725–1735.
  • Brunner D, Nurse P. CLIP170-like tip1p spatially organizes microtubular dynamics in fission yeast. Cell. 2000;102:695–704.
  • Busch K, Brunner D. The microtubule plus end-tracking proteins mal3p and tip1p cooperate for cell-end targeting of interphase microtubules. Curr Biol. 2004;14:548–559.
  • Mata J, Nurse P. tea1 and the microtubular cytoskeleton are important for generating global spatial order within the fission yeast cell. Cell. 1997;89:939–949.
  • Martin SG, McDonald WH, Yates JR, et al. Tea4p links microtubule plus ends with the formin For3p in the establishment of cell polarity. Dev Cell. 2005;8:479–491.
  • Tatebe H, Shimada K, Uzawa S, et al. Wsh3/Tea4 is a novel cell-end factor essential for bipolar distribution of Tea1 and protects cell polarity under environmental stress in S. pombe. Curr Biol. 2005;15:1006–1015.
  • Bimbo A, Jia Y, Poh SL, et al. Systematic deletion analysis of fission yeast protein kinases. Eukaryot Cell. 2005;4:799–813.
  • Koyano T, Kume K, Konishi M, et al. Search for kinases related to transition of growth polarity in fission yeast. Biosci Biotechnol Biochem. 2010;74:1129–1133.
  • Koyano T, Konishi M, Martin SG, et al. Casein kinase 1γ ensures monopolar growth polarity under incomplete DNA replication downstream of Cds1 and calcineurin in fission yeast. Mol Cell Biol. 2015;35:1533–1542.
  • Kume K, Hashimoto T, Suzuki M, et al. Identification of three signaling molecules required for calcineurin-dependent monopolar growth induced by the DNA replication checkpoint in fission yeast. Biochem Biophys Res Commun. 2017;491:883–889.
  • Cooklin EG. Cell size and nuclear size. J Exp Zool. 1912;12:1–98.
  • Jorgensen P, Edgington NP, Schneider BL, et al. The size of the nucleus increases as yeast cells grow. Mol Biol Cell. 2007;18:3523–3532.
  • Maeshima K, Iino H, Hihara S, et al. Nuclear size, nuclear pore number and cell cycle. Nucleus. 2011;2:113–118.
  • Harris H. The reactivation of the red cell nucleus. J Cell Sci. 1967;2:23–32.
  • Gurdon JB. Injected nuclei in frog oocytes: fate, enlargement, and chromatin dispersal. J Embryol Exp Morphol. 1976;36:523–540.
  • Hara Y, Merten CA. Dynein-based accumulation of membranes regulates nuclear expansion in Xenopus laevis egg extracts. Dev Cell. 2015;33:562–575.
  • Kim DU, Hayles J, Kim D, et al. Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe. Nat Biotechnol. 2010;28:617–623.
  • Kume K, Cantwell H, Neumann FR, et al. A systematic genomic screen implicates nucleocytoplasmic transport and membrane growth in nuclear size control. PLoS Genet. 2017;13:e1006767.
  • Kudo N, Matsumori N, Taoka H, et al. Leptomycine B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region. Proc Natl Acad Sci USA. 1999;96:9112–9117.
  • Ganguly A, Bhattachrjee C, Bhave M, et al. Perturbation of nucleocytoplasmic transport affects size of nucleus and nucleolus in human cells. FEBS Lett. 2016;590:631–643.
  • Brown JA, Bharathi A, Ghosh A, et al. A mutation in the Schizosaccharomyces pombe rae1 gene causes defects in poly(A)+RNA export and in the cytoskeleton. J Biol Chem. 1995;270:7411–7419.
  • Levy DL, Heald R. Nuclear size is regulated by importin alpha and Ntf2 in Xenopus. Cell. 2010;143:288–298.
  • Jevtic P, Edens LJ, Li X, et al. Concentration-dependent effects of nuclear lamins on nuclear size in Xenopus and mammalian cells. J Biol Chem. 2015;290:27557–27571.
  • Brownlee C, Heald R. Importin α partitioning to the plasma membrane regulates intracellular scaling. Cell. 2019;176:805–815.
  • Jevtic P, Schibler AC, Wesley CC, et al. The nucleoporin ELYS regulates nuclear size by controlling NPC number and nuclear import capacity. EMBO Rep. 2019;20:pii: e47283.
  • Cantwell H, Nurse P. A systematic genetic screen identifies essential factors involved in nuclear size control. PLoS Genet. 2019;15:e1007929.
  • Rothballer A, Schwartz TU, Kutay U. LINCing complex functions at the nuclear envelope: what the molecular architecture of the LINC complex can reveal about its function. Nucleus. 2013;4:29–36.
  • King MC, Drivas TG, Blobel G. A network of nuclear envelope membrane proteins linking centromeres to microtubules. Cell. 2008;134:427–438.
  • Kume K, Cantwell H, Burrell A, et al. Nuclear membrane protein Lem2 regulates nuclear size through membrane flow. Nat Commun. 2019;10:1871.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.