Knockdown of interferon-induced transmembrane protein 1 inhibited proliferation, induced cell cycle arrest and apoptosis, and suppressed MAPK signaling pathway in pancreatic cancer cells

References

• Lin QJ, Yang F, Jin C, et al. Current status and progress of pancreatic cancer in China. World J Gastroenterol. 2015;21:7988–8003.
   PubMed Web of Science ®Google Scholar
• Yan X, Hui Y, Hua Y, et al. EG-VEGF silencing inhibits cell proliferation and promotes cell apoptosis in pancreatic carcinoma via PI3K/AKT/mTOR signaling pathway. Biomed Pharmacother. 2019;109:762–769.
   PubMed Web of Science ®Google Scholar
• Mohammed A, Rao CV. Pancreatic cancer chemoprevention: challenges and opportunities. Curr Med Chem. 2018;25:2532–2534.
   PubMed Web of Science ®Google Scholar
• Karakas Y, Lacin S, Yalcin S. Recent advances in the management of pancreatic adenocarcinoma. Expert Rev Anticancer. 2018;18:51–62.
   PubMed Web of Science ®Google Scholar
• Liu F, Xia Z, Zhang M, et al. SMARCAD1 promotes pancreatic cancer cell growth and metastasis through Wnt/beta-catenin-mediated EMT. Int J Biol Sci. 2019;15:636–646.
   PubMed Web of Science ®Google Scholar
• Lee J, Goh SH, Song N, et al. Overexpression of IFITM1 has clinicopathologic effects on gastric cancer and is regulated by an epigenetic mechanism. Am J Pathol. 2012;181:43–52.
   PubMed Web of Science ®Google Scholar
• Yang YG, Koh YW, Sari IN, et al. Interferon-induced transmembrane protein 1-mediated EGFR/SOX2 signaling axis is essential for progression of non-small cell lung cancer. Int J Cancer. 2019;144:2020–2032.
   PubMed Web of Science ®Google Scholar
• Kim NH, Sung HY, Choi EN, et al. Aberrant DNA methylation in the IFITM1 promoter enhances the metastatic phenotype in an intraperitoneal xenograft model of human ovarian cancer. Oncol Rep. 2014;31:2139–2146.
   PubMed Web of Science ®Google Scholar
• Yan J, Jiang Y, Lu J, et al. Inhibiting of proliferation, migration, and invasion in lung cancer induced by silencing interferon-induced transmembrane protein 1 (IFITM1). Biomed Res Int. 2019;2019:9085435.
   PubMed Web of Science ®Google Scholar
• Yu F, Ng SS, Chow BK, et al. Knockdown of interferon-induced transmembrane protein 1 (IFITM1) inhibits proliferation, migration, and invasion of glioma cells. J Neuro-oncol. 2011;103:187–195.
   PubMed Web of Science ®Google Scholar
• Yu F, Xie D, Ng SS, et al. IFITM1 promotes the metastasis of human colorectal cancer via CAV-1. Cancer Lett. 2015;368:135–143.
   PubMed Web of Science ®Google Scholar
• Sari IN, Yang YG, Phi LT, et al. Interferon-induced transmembrane protein 1 (IFITM1) is required for the progression of colorectal cancer. Oncotarget. 2016;7:86039–86050.
   PubMedGoogle Scholar
• Zheng W, Zhao Z, Yi X, et al. Down-regulation of IFITM1 and its growth inhibitory role in cervical squamous cell carcinoma. Cancer Cell Int. 2017;17:88.
   PubMed Web of Science ®Google Scholar
• Yang J, Li L, Xi Y, et al. Combination of IFITM1 knockdown and radiotherapy inhibits the growth of oral cancer. Cancer Sci. 2018;109:3115–3128.
   PubMed Web of Science ®Google Scholar
• Fumoto S, Shimokuni T, Tanimoto K, et al. Selection of a novel drug-response predictor in esophageal cancer: a novel screening method using microarray and identification of IFITM1 as a potent marker gene of CDDP response. Int J Oncol. 2008;32:413–423.
   PubMed Web of Science ®Google Scholar
• Rogers CD, Fukushima N, Sato N, et al. Differentiating pancreatic lesions by microarray and QPCR analysis of pancreatic juice RNAs. Cancer Biol Ther. 2006;5:1383–1389.
   PubMed Web of Science ®Google Scholar
• Liu C, Zhang H, Zang X, et al. The influence of SnoN gene silencing by siRNA on the cell proliferation and apoptosis of human pancreatic cancer cells. Diagn Pathol. 2015;10:30.
   PubMed Web of Science ®Google Scholar
• Huang Q, Zhang J, Peng J, et al. Effect of baicalin on proliferation and apoptosis in pancreatic cancer cells. Am J Transl Res. 2019;11:5645–5654.
   PubMed Web of Science ®Google Scholar
• Lui AJ, Geanes ES, Ogony J, et al. IFITM1 suppression blocks proliferation and invasion of aromatase inhibitor-resistant breast cancer in vivo by JAK/STAT-mediated induction of p21. Cancer Lett. 2017;399:29–43.
   PubMed Web of Science ®Google Scholar
• Katary MA, Abdelsayed R, Alhashim A, et al. Salvianolic acid B slows the progression of breast cancer cell growth via enhancement of apoptosis and reduction of oxidative stress, inflammation, and angiogenesis. Int J Mol Sci. 2019;20:5653.
   Web of Science ®Google Scholar
• Yang G, Xu Y, Chen X, et al. IFITM1 plays an essential role in the antiproliferative action of interferon-gamma. Oncogene. 2007;26:594–603.
   PubMed Web of Science ®Google Scholar
• Meyer HJ, Gundermann P, Surov A. Associations between FDG-PET and Ki 67-index in head and neck cancer: a meta-analysis. Medicine (Baltimore). 2019;98:e17472.
   PubMedGoogle Scholar
• Kim SA, Kang OH, Kwon DY. Cryptotanshinone induces cell cycle arrest and apoptosis of NSCLC cells through the PI3K/Akt/GSK-3beta pathway. Int J Mol Sci. 2018;19:2739.
   Web of Science ®Google Scholar
• Xia P, Liu P, Fu Q, et al. Long noncoding RNA EPIC1 interacts with YAP1 to regulate the cell cycle and promote the growth of pancreatic cancer cells. Biochem Biophys Res Commun. 2020;522:978-985.
   Web of Science ®Google Scholar
• Zhong ZQ, Song MM, He Y, et al. Knockdown of Ezrin by RNA interference reverses malignant behavior of human pancreatic cancer cells in vitro. Asian Pac J Cancer Prev. 2012;13:3781–3789.
   PubMedGoogle Scholar
• Jin B, Jin H, Wang J. Silencing of interferon-induced transmembrane protein 1 (IFITM1) inhibits proliferation, migration, and invasion in lung cancer cells. Oncol Res. 2017. DOI:10.3727/096504017X14844360974116
   Web of Science ®Google Scholar
• Yoo ES, Choo GS, Kim SH, et al. Antitumor and apoptosis-inducing effects of piperine on human melanoma cells. Anticancer Res. 2019;39:1883–1892.
   PubMed Web of Science ®Google Scholar
• Wang Y, Sun L, Luo Y, et al. Knockdown of KDM1B inhibits cell proliferation and induces apoptosis of pancreatic cancer cells. Pathol Res Pract. 2019;215:1054–1060.
   PubMed Web of Science ®Google Scholar
• Tassone P, Tagliaferri P, Viscomi C, et al. Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro. Br J Cancer. 2003;88:1971–1978.
   PubMed Web of Science ®Google Scholar
• Mohammad J, Singh RR, Riggle C, et al. JNK inhibition blocks piperlongumine-induced cell death and transcriptional activation of heme oxygenase-1 in pancreatic cancer cells. Apoptosis. 2019;24:730–744.
   PubMed Web of Science ®Google Scholar
• Wu Y, Tan X, Liu P, et al. ITGA6 and RPSA synergistically promote pancreatic cancer invasion and metastasis via PI3K and MAPK signaling pathways. Exp Cell Res. 2019;379:30–47.
   PubMed Web of Science ®Google Scholar
• Wang Y, Bu C, Wu K, et al. Curcumin protects the pancreas from acute pancreatitis via the mitogen-activated protein kinase signaling pathway. Mol Med Rep. 2019;20:3027–3034.
   PubMed Web of Science ®Google Scholar
• Chen Q, Yang C, Chen L, et al. YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways. Br J Cancer. 2019;121:912–921.
   PubMed Web of Science ®Google Scholar
• Kim JY, Kim H, Suk K, et al. Activation of CD147 with cyclophilin A induces the expression of IFITM1 through ERK and PI3K in THP-1 cells. Mediators Inflammation. 2010;2010:821940.
   PubMed Web of Science ®Google Scholar
• Xu Y, Yang G, Hu G. Binding of IFITM1 enhances the inhibiting effect of caveolin-1 on ERK activation. Acta Biochim Biophys Sin. 2009;41:488–494.
   Google Scholar