875
Views
45
CrossRef citations to date
0
Altmetric
Articles

Mechanical and structural response of a hybrid hydrogel based on chitosan and poly(vinyl alcohol) cross-linked with epichlorohydrin for potential use in tissue engineering

, , , , , , , & show all
Pages 32-50 | Received 18 May 2013, Published online: 05 Sep 2013

References

  • United States Organ Transplantation [Internet]. OPTN & SRTR annual data report 2011. Available from: http://optn.transplant.hrsa.gov/data/annualReport.asp.
  • Billet T, Vandenhuate M, Schelfhout J, Van Vlierberghe S, Dubruel P. A review of trends and limitations in hydrogel-rapid prototyping for tissue engineering. Biomaterials. 2012;33:6020–6041.
  • Peltola SM, Melchels FPW, Grijpma DW, Kellomaki M. A review of rapid prototyping techniques for tissue engineering purposes. Ann. Med. 2008;40:268–280.
  • Yeong WY, Chua CK, Leong KF, Chandrasekaran M. Rapid prototyping in tissue engineering: challenges and potential. Trends Biotechnol. 2004;22:643–652.
  • Nguyen DT, McCanless JD, Mecwan MM, Noblett AP, Haggard WO, Smith RA, Bumgardner JD. Balancing mechanical strength with bioactivity in chitosan–calcium phosphate 3D microsphere scaffolds for bone tissue engineering: air- vs. freeze-drying processes. J. Biomater. Sci., Polym. Ed. 2012;24:1–13.
  • Bansal V, Sharma PK, Sharma N, Pal OP, Malviya R. Applications of chitosan and chitosan derivatives in drug delivery. Adv. Biol. Res. 2011;1:28–37.
  • Baker MI, Walsh SP, Schwartz Z, Boyan BD. A review of polyvinyl alcohol and its uses in cartilage and orthopaedic applications. J. Biomed. Mater. Res. B Appl. Biomater. 2012;100B:1451–1457.
  • El-Hefian EA, Nasef MM, Yahaya AH. The preparation and characterization of chitosan poly(vinyl alcohol) blended films. E-J. Chem. 2010;7:1212–1219.
  • Azevedo PA, Retarekar R, Raghavan ML, Kumar V. Mechanical properties of cellulose: chitosan blends for potential use as a coronary artery bypass graft. J. Biomater. Sci., Polym. Ed. 2012;24:1–14.
  • Stammen JA, Williams S, Ku DN, Guldberg RE. Mechanical properties of a novel PVA hydrogel in shear and unconfined compression. Biomaterials. 2001;22:799–806.
  • Thomas LV, Arun U, Remya S, Nair PD. A biodegradable and biocompatible PVA – citric acid polyester with potential applications as matrix for vascular tissue engineering. J. Mater. Sci. -Mater. Med. 2009;20:S259–269.
  • Borzacchiello A, Ambrosio L, Netti PA, Nicolais L, Peniche C, Gallardo A, San Roman J. Chitosan-based hydrogels: synthesis and characterization. J. Mater. Sci. -Mater. Med. 2001;12:861–864.
  • Di Martino A, Sittinger M, Risbud MV. Chitosan: a versatile biopolimer for orthopedic tissue-engineering. Biomaterials. 2005;26:5983–5990.
  • Khor E, Lim LY. Implantable applications of chitin and chitosan. Biomaterials. 2003;24:2339–2349.
  • Zhong X, Ji C, Chan AK, Kazarian SG, Ruys A, Dehghani F. Fabrication of chitosan/poly(ϵ-caprolactone) composite hydrogels for tissue engineering applications. J. Mater. Sci. -Mater. Med. 2011;22:279–288.
  • El-Hefian EA, Nasef MM, Yahaya AH. Preparation and characterization of chitosan/poly(vinyl alcohol) blended films: mechanical, thermal and surface investigations. E-J. Chem. 2011;8:91–96.
  • Zhuang PY, Li YL, Fan L, Lin J, Hu QL. Modification of chitosan membrane with poly(vinyl alcohol) and biocompatibility evaluation. Int. J. Biol. Macromol. 2012;50:658–663.
  • He Z, Xiong L. Evaluation of physical and biological properties of polyvinyl alcohol/chitosan blend films. J. Macromol. Sci. Part B Phys. 2012;51:1705–1714.
  • Yoshimatsu G, Sakata N, Tsuchiya H, Ishida M, Motoi F, Egawa S, Sumi S, Goto M, Unno M. Development of polyvinyl alcohol bioartificial pancreas with rat islets and mesenchymal stem cells. Transpl. Proc. 2013;45:1875–1880.
  • Alhosseini SN, Moztarzadeh F, Mozafari F, Asgari S, Dodel M, Samadikuchaksaraei A, Kargozar S, Jalali N. Synthesis and characterization of electrospun polyviniyl alcohol nanofibrous scaffolds modified by blending with chitosan for neural tissue engineering. Int. J. Nanomed. 2012;7:25–34.
  • Costa-Junior ES, Pereira MM, Mansur HS. Properties and biocompatibility of chitosan films modified by blending with PVA and chemically crosslinked. J. Mater. Sci. -Mater. Med. 2009;20:553–561.
  • Costa-Junior ES, Barbosa-Stancoli EF, Mansur AAP, Vasconcelos WL, Mansur HS. Preparation and characterization of chitosan/poly(vinyl alcohol) chemically crosslinked blends for biomedical applications. Carbohydr. Polym. 2009;76:472–481.
  • Park H, Kim D. Swelling and mechanical properties of glycol chitosan/poly(vinyl alcohol) IPN-type superporous hydrogels. J. Biomed. Mater. Res. A. 2006;78:662–667.
  • Bo J. Study on PVA hydrogel crosslinked by epichlorohydrine. J. Appl. Polym. Sci. 1992;46:783–786.
  • Schmedlen RH, Masters KS, West JL. Photocrosslinkable polyvinyl alcohol hydrogels that can be modified with cell adhesion peptides for use in tissue engineering. Biomaterials. 2002;23:4325–4332.
  • Bahrami SB, Kordestani SS, Mirzadeh H, Mansoori P. Poly(vinyl alcohol)-chitosan blends: preparation, mechanical and physical properties. Iran Polym. J. 2003;12:139–146.
  • Mathews DT, Birney YA, Cahill PA, McGuinness GB. Mechanical and morphological characteristics of poly(vinyl alcohol)/chitosan hydrogels. J. Appl. Polym. Sci. 2008;19:1129–1137.
  • Bispo VM, Mansur AAP, Barbosa-Stancioli EF, Mansur HS. Biocompatibility of nanostructured chitosan/poly(vinyl alcohol) blends chemically crosslinked with genipin for biomedical applications. J. Biomed. Nanotechnol. 2010;6(2):166–175.
  • Anseth KS, Bowman CN, Brannon-Peppas L. Mechanical properties of hydrogels and their experimental determination. Biomaterials. 1996;17:1647–1657.
  • Treloar LRG. The Physics of Rubber Elasticity. New York, NY: Oxford University Press; 2005.
  • Jin Y, Yang D, Zhou Y, Ma G, Nie J. Photocrosslinked electrospun chitosan-based biocompatible nanofibers. J. Appl. Polym. Sci. 2008;109:3337–3343.
  • Omidian H, Park K. Biomedical applications of hydrogels handbook. New York, NY: Springer; 2010.
  • Shukla S, Bajpai AK. Preparation and characterization of highly swelling smart grafted polymer networks of poly(vinyl alcohol) and poly(acrylic acid-co-acrylamide. J. Appl. Polym. Sci. 2006;102:84–95.
  • ASTM Standard F2150/02. ASTM standard guide for characterization and testing of biomaterial scaffolds used in tissue-engineered medical products. 2004.
  • ASTM Standard D882/02. ASTM standard test method for tensile properties of thin plastic sheeting. 2004.
  • Sánchez-Arévalo FM, Pulos G. Use of digital image correlation to determine the mechanical behavior of materials. Mater. Charact. 2008;59:1572–1579.
  • Jeon O, Jin Song S, Lee KJ, Park MH, Lee SH, Hahn SK, Kim S, Kim BS. Mechanical properties and degradation behaviors of hyaluronic acid hydrogels cross-linked at various cross-linking densities. Carbohydr. Polym. 2007;70:251–257.
  • Peppas NA, Merril EW. Crosslinked poly(vinyl alcohol) hydrogels as swollen elastic networks. J. Appl. Polym. Sci. 1977;21:1763–1770.
  • Sánchez-Arévalo FM, Farfán M, Covarrubias D, Zenit R, Pulos G. The micromechanical behavior of lyophilized glutaraldehyde-treated bovine pericardium under uniaxial tension. J. Mech. Behav. Biomed. 2010;3:640–646.
  • D’Errico G, De Lellis M, Mangiapia G, Tedeschi A, Ortona O, Fusco S, Borzachiello A, Ambrosio L. Structural and mechanical properties of UV-photo-cross-linked poly(N-vinyl-2-pyrrolidone) hydrogels. Biomacromolecules. 2008;9:231–240.
  • Peppas NA, Mikos AG. Hydrogels in medicine and pharmacy: Vols. 1–2. Boca Ratón, FL: CRC Press; 1987.
  • Flory PJ. Principles of polymer chemistry. New York, NY: Cornell University Press; 1953.
  • Liu Y, Vrana NE, Cahill PA, McGuinnes GB. Physically crosslinked composite hydrogels of PVA with natural macromolecules: structure, mechanical properties and endothelial cell compatibility. J. Biomed. Mater. Res. B. 2009;90:492–502.
  • Neamnark A, Sanchavanakit N, Pavasant P, Bunaprasert T, Supaphol P, Rujiravanit R. In vitro biocompatibility evaluations of hexanoyl chitosan film. Carbohydr. Polym. 2007;68:166–172.
  • Hua S, Wang A. Synthesis, characterization and swelling behaviors of sodium alginate-g-poly(acrylic acid)/sodium humate superabsorbent. Carbohydr. Polym. 2009;75:79–84.
  • Sundaram G, Wang T, Chai C. Swelling of pH-sensitive chitosan-poly(vinyl alcohol) hydrogels. J. Appl. Polym. Sci. 2006;102:4665–4671.
  • Berger J, Reist M, Mayer JM, Felt O, Peppas NA, Gurny R. Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications. J. Pharm. Biopharm. 2004;57:19–34.
  • Berger J, Reist M, Mayer JM, Felt O, Gurny R. Structure and interactions in chitosan hydrogels formed by complexation or aggregation for biomedical applications. J. Pharm. Biopharm. 2004;57:35–52.
  • Narayan R. Biomedical materials. New York, NY: Springer; 2009.
  • Ruiz J, Mantecón A, Cádiz V. Network characterization and swelling behavior of chemical hydrogels based on acid-containing poly(vinyl alcohol). J. Appl. Polym. Sci. 2003;88:3026–3031.
  • Song Y, Li L, Zheng Q. Influence of epichlorohydrin modification on structure and properties of wheat gliadin films. J. Agric. Food Chem. 2009;57:2295–2301.
  • Gent AN. Engineering with rubber: how to design rubber components. Munich: Hanser; 2001.
  • Li J, Suo J, Deng R. Structure, mechanical, and swelling behaviors of poly(vinyl alcohol)/SiO2 hybrid membranes. J. Reinf. Plast. Compos. 2010;29:618–629.
  • Chen SH, Tsao CT, Chang CH, Lai YT, Wu MF, Liu ZW, Chuang CN, Chou HC, Wang CK, Hsieh KH. Synthesis and characterization of reinforced poly(ethylene glycol)/chitosan hydrogel as wound dressing materials. Macromol. Mater. Eng. 2013;298:429–438.
  • Knaul JZ, Hudson SM, Creber KAM. Crosslinking of chitosan fibers with dialdehydes: proposal of a new reaction mechanism. J. Polym. Sci., Part B: Polym. Phys. 1999;37:1079–1074.
  • Mi FL, Tan YC, Liang HC, Huang RN, Sung HW. In vitro evaluation of a chitosan membrane cross-linked with genipin. J. Biomater. Sci., Polym. Ed. 2001;12:835–850.
  • Park SS, Chi DH, Lee AS, Taylor SR, Iezzoni J. Biomechanical properties of tissue engineered cartilage from human and rabbit chondrocytes. Otolaryng. Head Neck. 2002;126:52–57.
  • Park SS, Jin HR, Chi DH, Taylor RS. Characteristics of tissue-engineered cartilage from human auricular chondrocytes. Biomaterials. 2004;25:2363–2369.
  • Cauich-Rodriguez JV, Deb S, Smith R. Effect of cross-linking agents on the dynamic mechanical properties of hydrogel blends of poly(acrylic acid)-poly(viny1 alcohol-vinyl acetate). Biomaterials. 1996;17:2259–2264.
  • Sanabria-DeLong N, Crosby AJ, Tew GN. Photo-Cross-Linked PLA-PEO-PLA hydrogels from self-assembled physical networks: mechanical properties and influence of assumed constitutive relationships. Biomacromolecules. 2008;9:2784–2791.
  • Krishna L, Jayabalan M. Synthesis and characterization of biodegradable poly(ethylene glycol) and poly(caprolactonediol) end capped poly(propylene fumarate) crosslinked amphiphilic hydrogel as tissue engineering scaffold material. J. Mater. Sci. -Mater. Med. 2009;20:S115–S122.
  • Borzacchiello A, Ambrosio L. Hydrogels: biological properties and applications. Milan: Springer-Verlag; 2009.
  • Wang QG, Hughes N, Cartmell SH, Kuiper NJ. The composition of hydrogels for cartilage tissue engineering can influence glycosaminoglycan profiles. Eur. Cells Mater. 2010;19:86–95.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.