Microstructured titanium functionalized by naringin inserted multilayers for promoting osteogenesis and inhibiting osteoclastogenesis

References

• Lin X, Xiong D, Peng YQ, et al. Epidemiology and management of osteoporosis in the People's Republic of China: current perspectives. Clin Interv Aging. 2015;10:1017–1033.
   PubMed Web of Science ®Google Scholar
• Frost HM. Defining osteopenias and osteoporoses: Another view (with insights from a new paradigm. Bone. 1997;20(5):385–391.
   PubMed Web of Science ®Google Scholar
• Geetha M, Singh AK, Asokamani R, et al. Ti based biomaterials, the ultimate choice for orthopaedic implants – a review. Prog Mater Sci. 2009;54(3):397–425.
   Web of Science ®Google Scholar
• Karthika P, Olha B, Ming C, et al. Metallic biomaterials: current challenges and opportunities. Materials. 2017;10(8):884.
   Web of Science ®Google Scholar
• Minagar S, Berndt CC, Wang J, et al. A review of the application of anodization for the fabrication of nanotubes on metal implant surfaces. Acta Biomater. 2012;8(8):2875–2888.
   PubMed Web of Science ®Google Scholar
• Ban S, Iwaya Y, Kono H, et al. Surface modification of titanium by etching in concentrated sulfuric acid. Dent Mater. 2006;22(12):1115–1120.
   PubMed Web of Science ®Google Scholar
• Wang ZS, Wu GS, Feng ZH, et al. Microarc-oxidized titanium surfaces functionalized with microRNA-21-loaded chitosan/hyaluronic acid nanoparticles promote the osteogenic differentiation of human bone marrow mesenchymal stem cells. Int J Nanomed. 2015;10:6675–6687.,
   PubMed Web of Science ®Google Scholar
• Xiong JY, Li YC, Wang XJ, et al. Mechanical properties and bioactive surface modification via alkali-heat treatment of a porous Ti-18Nb-4Sn alloy for biomedical applications. Acta Biomater. 2008;4(6):1963–1968.
   PubMed Web of Science ®Google Scholar
• Hirata M, Matsumoto C, Takita M, et al. Naringin suppresses osteoclast formation and enhances bone mass in mice. J Health Sci. 2009;55(3):463–467.
   Google Scholar
• Yu MF, You DQ, Zhuang JJ, et al. Controlled release of naringin in metal-organic framework-loaded mineralized collagen coating to simultaneously enhance osseointegration and antibacterial activity. ACS Appl Mater Interfaces. 2017;9(23):19698–19705.
   PubMed Web of Science ®Google Scholar
• Ji Y, Wang L, Watts DC, et al. Controlled-release naringin nanoscaffold for osteoporotic bone healing. Dent Mater. 2014;30(11):1263–1273.
   PubMed Web of Science ®Google Scholar
• Lai M, Jin ZY, Yan MY, et al. The controlled naringin release from TiO2 nanotubes to regulate osteoblast differentiation. J Biomater Appl. 2018;33(5):673–680.,
   PubMed Web of Science ®Google Scholar
• Brett CMA. Perspectives and challenges for self-assembled layer-by-layer biosensor and biomaterial architectures. Curr Opin Electroche. 2018;12:21–26.
   Web of Science ®Google Scholar
• Ren KF, Hu M, Zhang H, et al. Layer-by-layer assembly as a robust method to construct extracellular matrix mimic surfaces to modulate cell behavior. Prog Polym Sci. 2019;92:1–34.
   Web of Science ®Google Scholar
• Liu X, Ma L, Mao ZW, et al. Chitosan-based biomaterials for tissue repair and regeneration. Adv Polym Sci. 2011;244:81–127.
   Web of Science ®Google Scholar
• Yang SS, Wang Y, Luo S, et al. Building polyphenol and gelatin films as implant coating, evaluating from in vitro and in vivo performances. Colloids Surf B Biointerfaces. 2019;181:549–560.,
   PubMed Web of Science ®Google Scholar
• Hu Y, Cai KY, Luo Z, et al. Regulation of the differentiation of mesenchymal stem cells in vitro and osteogenesis in vivo by microenvironmental modification of titanium alloy surfaces. Biomaterials. 2012;33(13):3515–3528.,
   PubMed Web of Science ®Google Scholar
• Webster TJ, Ergun C, Doremus RH, et al. Enhanced functions of osteoblasts on nanophase ceramics. Biomaterials. 2000;21(17):1803–1810.,
   PubMed Web of Science ®Google Scholar
• Lai M, Cai KY, Zhao L, et al. Surface functionalization of TiO2 nanotubes with bone morphogenetic protein 2 and its synergistic effect on the differentiation of mesenchymal stem cells. Biomacromolecules. 2011;12(4):1097–1105.,
   PubMed Web of Science ®Google Scholar
• Lavrador P, Gaspar VM, Mano JF. Bioinspired bone therapies using naringin: applications and advances. Drug Discov Today. 2018;23(6):1293–1304.
   PubMed Web of Science ®Google Scholar
• Lee H, Rho J, Messersmith PB. Facile conjugation of biomolecules onto surfaces via mussel adhesive protein inspired coatings. Adv Mater. 2009;21(4):431–434.
   PubMed Web of Science ®Google Scholar
• Lee H, Dellatore SM, Miller WM, et al. Mussel-inspired surface chemistry for multifunctional coatings. Science. 2007;318(5849):426–430.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Chen L, Liu C, et al. Self-assembly chitosan/gelatin composite coating on icariin-modified TiO2 nanotubes for the regulation of osteoblast bioactivity. Mater Design. 2016;92:471–479.,
   Web of Science ®Google Scholar
• Lai M, Yan XF, Jin ZY. The response of bone cells to titanium surfaces modified by simvastatin-loaded multilayered films. J Biomater Sci Polym Ed. 2018;29(15):1895–1908.
   PubMed Web of Science ®Google Scholar
• Wlodarski KH, Reddi AH. Alkaline phosphatase as a marker of osteoinductive cells. Calcif Tissue Int. 1986;39(6):382–385.
   PubMed Web of Science ®Google Scholar
• Venugopal JR, Dev VRG, Senthilram T, et al. Osteoblast mineralization with composite nanofibrous substrate for bone tissue regeneration. Cell Biol Int. 2011;35(1):73–80.
   PubMed Web of Science ®Google Scholar
• Gregory CA, Gunn WG, Peister A, et al. An Alizarin red-based assay of mineralization by adherent cells in culture: comparison with cetylpyridinium chloride extraction. Anal Biochem. 2004;329(1):77–84.
   PubMed Web of Science ®Google Scholar
• Guo L-H, Cao Y, Zhuang R-T, et al. Effects of naringin on the proliferation, migration and osteogenesis of two human osteoblast-like cell lines. J Biomater Tissue Eng. 2018;8(6):871–879.,
   Web of Science ®Google Scholar
• Shang N, Bhulla KS, Hubbard BP, et al. Tripeptide IRW initiates differentiation in osteoblasts differentiation via the RUNX2 pathway. Biochim Biophys Acta Gen Subj. 2019;1863(6):1138–1146.
   PubMed Web of Science ®Google Scholar
• Brun LR, Lombarte M, Roma S, et al. Increased calcium uptake and improved trabecular bone properties in intestinal alkaline phosphatase knockout mice. J Bone Miner Metab. 2018;36(6):661–667.
   PubMed Web of Science ®Google Scholar
• Lynch MP, Stein JL, Stein GS, et al. The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passaged rat calvarial osteoblasts: modification of expression of genes supporting cell growth, adhesion, and extracellular matrix mineralization. Exp Cell Res. 1995;216(1):35–45.
   PubMed Web of Science ®Google Scholar
• Kavukcuoglu NB, Patterson-Buckendahl P, Mann AB. Effect of osteocalcin deficiency on the nanomechanics and chemistry of mouse bones. J Mech Behav Biomed Mater. 2009;2(4):348–354.
   PubMed Web of Science ®Google Scholar
• Dong M, Yu XX, Chen WF, et al. Osteopontin promotes bone destruction in periapical periodontitis by activating the NF-κB pathway. Cell Physiol Biochem. 2018;49(3):884–898., 2018
   PubMedGoogle Scholar
• Chen DY, Liu Y, Liu ZX, et al. OPG is required for the postnatal maintenance of condylar cartilage. Calcif Tissue Int. 2019;104(4):461–474.
   PubMed Web of Science ®Google Scholar
• Wang HC, Li CB, Li JM, et al. Naringin enhances osteogenic differentiation through the activation of ERK signaling in human bone marrow mesenchymal stem cells. Iran J Basic Med Sci. 2017;20(4):408–414.
   PubMed Web of Science ®Google Scholar
• Kuang MJ, Zhang WH, He WW, et al. Naringin regulates bone metabolism in glucocorticoid-induced osteonecrosis of the femoral head via the Akt/Bad signal cascades. Chem Biol Interact. 2019;304:97–105.,
   PubMed Web of Science ®Google Scholar
• Cao X, Lin W, Liang C, et al. Naringin rescued the TNF-α-induced inhibition of osteogenesis of bone marrow-derived mesenchymal stem cells by depressing the activation of NF-кB signaling pathway. Immunol Res. 2015;62(3):357–367.,
   PubMed Web of Science ®Google Scholar
• Li FB, Sun XL, Ma JX, et al. Naringin prevents ovariectomy-induced osteoporosis and promotes osteoclasts apoptosis through the mitochondria-mediated apoptosis pathway. Biochem Biophys Res Commun. 2014;452(3):629–635.
   PubMed Web of Science ®Google Scholar
• Ang ESM, Yang XH, Chen HH, et al. Naringin abrogates osteoclastogenesis and bone resorption via the inhibition of RANKL-induced NF-κB and ERK activation. FEBS Lett. 2011;585(17):2755–2762.,
   PubMed Web of Science ®Google Scholar
• Rochet N, Balaguer T, Boukhechba F, et al. Differentiation and activity of human preosteoclasts on chitosan enriched calcium phosphate cement. Biomaterials. 2009;30(26):4260–4267.
   PubMed Web of Science ®Google Scholar
• Blumer MJF, Hausott B, Schwarzer C, et al. Role of tartrate-resistant acid phosphatase (TRAP) in long bone development. Mech Dev. 2012;129(5–8):162–176.,
   PubMed Web of Science ®Google Scholar
• Pan WY, Yin WW, Yang Li, et al. Inhibition of Ctsk alleviates periodontitis and comorbid rheumatoid arthritis via downregulation of the TLR9 signalling pathway. J Clin Periodontol. 2019;46(3):286–296.
   PubMed Web of Science ®Google Scholar
• Russo R, Mallia S, Zito F, et al. Gene expression profiling of NFATc1-knockdown in RAW 264.7 cells: an alternative pathway for macrophage differentiation, cells. Cells. 2019;8(2):131.
   Web of Science ®Google Scholar
• Katara GK, Jaiswal MK, Kulshrestha A, et al. Tumor-associated vacuolar ATPase subunit promotes tumorigenic characteristics in macrophages. Oncogene. 2014;33(49):5649–5654.,
   PubMed Web of Science ®Google Scholar