Study on preparation, compression strength and theophylline/diclofenac sodium release ability of NIPAAm/DMAPMAAm hydrogels

References

• Fujishige S, Kubota K, Ando I. Phase transition of aqueous solutions of poly (N-isopropylacrylamide) and poly (N-isopropylmethacrylamide). J Phys Chem. 1989;93(8):3311–3313.
   Web of Science ®Google Scholar
• Schild HG. Poly (N-isopropylacrylamide): experiment, theory and application. Prog Polym Sci. 1992;17(2):163–249.
   Web of Science ®Google Scholar
• Takigawa T, Yamawaki T, Takahashi K, et al. Change in young’s modulus of poly(N-isopropylacrylamide) gels by volume phase transition. Polym Gels Netw. 1998;5(6):585–589.
   Google Scholar
• Haq MA, Su Y, Wang D. Mechanical properties of PNIPAM based hydrogels: a review. Mater Sci Eng C Mater Biol Appl. 2017;70(Pt 1):842–855.
   PubMedGoogle Scholar
• Chatterjee S, Hui P. C-L. Review of stimuli-responsive polymers in drug delivery and textile application. Molecules. 2019;24(14):2547.
   PubMed Web of Science ®Google Scholar
• Li Z, Guan J. Thermosensitive hydrogels for drug delivery. Expert Opin Drug Deliv. 2011;8(8):991–1007.
   PubMed Web of Science ®Google Scholar
• Aguilar MR, Elvira C, Gallardo A, et al. Smart polymers and their applications as biomaterials. Top Tissue Eng. 2007;3:12–16.
   Google Scholar
• You J-O, Almeda D, George JC, et al. Bioresponsive matrices in drug delivery. J Biol Eng. 2010;4:15.
   PubMedGoogle Scholar
• Jin C, Song W, Liu T, et al. Temperature and pH responsive hydrogels using methacrylated lignosulfonate cross-linker: Synthesis, characterization, and properties. ACS Sustain Chem Eng. 2018;6(2):1763–1771.
   Web of Science ®Google Scholar
• Gao X, Cao Y, Song X, et al. pH- and thermo-responsive poly(N-isopropylacrylamide-co-acrylic acid derivative) copolymers and hydrogels with LCST dependent on pH and alkyl side groups. J Mater Chem B. 2013;1(41):5578–5587.
   PubMed Web of Science ®Google Scholar
• Deen GR, Loh XJ. Stimuli-responsive cationic hydrogels in drug delivery applications. Gels. 2018;4:13.
   PubMed Web of Science ®Google Scholar
• Moselhy J, Sarkar S, Chia MC, et al. Evaluation of copolymers of N-isopropylacrylamide and 2-dimethyl (aminoethyl) methacrylate in non-viral and adenoviral vectors for gene delivery to nasopharyngeal carcinoma. Int J Nanomedicine. 2007;2:461–478.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Xu L, Yi M, et al. Radiation synthesis of poly [(dimethylaminoethyl methacrylate)-co-(diallyl dimethyl ammonium chloride)] hydrogels and its application as a carrier for notoginsenoside delivery. Eur Polym J. 2006;42(11):2959–2967.
   Google Scholar
• Salehi R, Alizadeh E, Kafil HS, et al. pH-controlled multiple-drug delivery by a novel antibacterial nanocomposite for combination therapy. RSC Adv. 2015;5(128):105678–105691.
   Web of Science ®Google Scholar
• Guo S, Qiao Y, Wang W, et al. Poly(ε-caprolactone)-graft-poly(2-(N, N-dimethylamino) ethyl methacrylate) nanoparticles: pH dependent thermo-sensitive multifunctional carriers for gene and drug delivery. J Mater Chem. 2010;20(33):6935–6941.
   Web of Science ®Google Scholar
• Yu Y, Cheng Y, Tong J, et al. Recent advances in thermo-sensitive hydrogels for drug delivery. J Mater Chem B. 2021;9(13):2979–2992.
   PubMed Web of Science ®Google Scholar
• Roshan Deen G, Loh XJ. Stimuli-responsive cationic hydrogels in drug delivery application. Gels. 2018; 4:1–13.
   Web of Science ®Google Scholar
• van de Wetering P, Moret EE, Schuurmans-Nieuwenbroek NME, et al. Structure-activity relationships of water-soluble cationic methacrylate/methacrylamide polymers for nonviral gene delivery. Bioconjug Chem. 1999;10(4):589–597.
   PubMed Web of Science ®Google Scholar
• Paslay LC, Abel BA, Brown TD, et al. Antimicrobial poly(methacrylamide) derivatives prepared via aqueous RAFT polymerization exhibit biocidal efficiency dependent upon cation structure. Biomacromolecules. 2012;13(8):2472–2482.
   PubMed Web of Science ®Google Scholar
• Du J, Wu R, Liu H, et al. Synthesis of amphoteric nanocomposite hydrogels with ultrahigh tensibility. Polym Compos. 2015;36(3):538–544.
   Web of Science ®Google Scholar
• Nie X, Adalati A, Du J, et al. Preparation of amphoteric nanocomposite hydrogels based on exfoliation of montmorillonite via in-situ intercalative polymerization of hydrophilic cationic and anionic monomers. Appl Clay Sci. 2014;97-98:132–137.
   Web of Science ®Google Scholar
• Park TG, Hoffman AS. Synthesis and characterization of pH-and/or temperature-sensitive hydrogels. J Appl Polym Sci. 1992;46(4):659–671.
   Web of Science ®Google Scholar
• Park TG. Temperature modulated protein release from pH/temperature-sensitive hydrogels. Biomaterials. 1999;20(6):517–521.
   PubMed Web of Science ®Google Scholar
• Eke I, Elmas B, Tuncel M, et al. A new, highly stable cationic-thermosensitive microgel: Uniform isopropylacrylamide-dimethylaminopropylmethacrylamide copolymer particles. Colloids Surf A Physicochem Eng Asp. 2006;279(1-3):247–253.
   Web of Science ®Google Scholar
• Patel T, Ghosh G, Yusa S, et al. Solution behavior of poly (N-isopropylacrylamide) in water: effect of additives. J Dispers Sci Technol. 2011;32(8):1111–1118.
   Web of Science ®Google Scholar
• Bischofberger I, Calzolari DCE, De Los Rios P, et al. Hydrophobic hydration of poly-N-isopropyl acrylamide: a matter of the mean energetic state of water. Sci Rep. 2014;4:1–7.
   Web of Science ®Google Scholar
• Kitano H, Nagaoka K, Tada S, et al. Structure of water in the vicinity of amphoteric polymers as revealed by Raman spectroscopy. J Colloid Interface Sci. 2007;313(2):461–468.
   PubMed Web of Science ®Google Scholar
• Kitano H, Imai M, Sudo K, et al. Hydrogen-bonded network structure of water in aqueous solution of sulfobetaine polymers. J Phys Chem B. 2002;106(43):11391–11396.
   Web of Science ®Google Scholar
• Park TG, Hoffman AS. Sodium chloride-induced phase transition in nonionic poly (N-isopropylacrylamide) gel. Macromolecules. 1993;26(19):5045–5048.
   Web of Science ®Google Scholar
• Zhang Y, Furyk S, Bergbreiter DE, et al. Specific ion effects on the water solubility of macromolecules: PNIPAM and the hofmeister series. J Am Chem Soc. 2005;127(41):14505–14510.
   PubMed Web of Science ®Google Scholar
• Kumar A, Srivastava A, Galaev IY, et al. Smart polymers: physical forms and bioengineering applications. Prog Polym Sci. 2007;32(10):1205–1237.
   Web of Science ®Google Scholar
• Algaer EA, van der Vegt NFA. Hofmeister ion interactions with model amide compounds. J Phys Chem B. 2011;115(46):13781–13787.
   PubMed Web of Science ®Google Scholar
• Peppas NA, Sahlin JJ. A simple equation for the description of solute release. III. Coupling of diffusion and relaxation. Int J Pharm. 1989;57(2):169–172.
   Web of Science ®Google Scholar
• Bruschi ML. Strategies to modify the drug release from pharmaceutical systems. England: Woodhead Publishing; 2015.
   Google Scholar
• Brazel CS, Peppas NA. Mechanisms of solute and drug transport in relaxing, swellable, hydrophilic glassy polymers. Polymer. 1999;40(12):3383–3398.
   Web of Science ®Google Scholar
• Machin R, Isasi JR, Vélaz I. Hydrogel matrices containing single and mixed natural cyclodextrins. Mechanisms of drug release. Eur Polym J. 2013;49(12):3912–3920.
   Web of Science ®Google Scholar
• Wong RSH, Dodou K. Effect of drug loading method and drug physicochemical properties on the material and drug release properties of poly (ethylene oxide) hydrogels for transdermal delivery. Polymers. 2017;9:286.
   PubMed Web of Science ®Google Scholar
• Dumitriu RP, Oprea A-M, Natalia Cheaburu C, et al. Biocompatible and biodegradable alginate/poly (N-isopropylacrylamide) hydrogels for sustained theophylline release. J Appl Polym Sci. 2014;131:40733.
   Web of Science ®Google Scholar
• Fardous J, Perveen FF, Saifuddin AHM, et al. Preparation and evaluation of an anti-asthmatic gel of theophylline with diclofenac sodium. JAPLR. 2019;8(2):65–69.
   Google Scholar
• Curcio M, Spizzirri UG, Iemma F, et al. Grafted thermo-responsive gelatin microspheres as delivery systems in triggered drug release. Eur J Pharm Biopharm. 2010;76(1):48–55.
   PubMed Web of Science ®Google Scholar
• Yalçın B, Erbil C. Effect of sodium hydroxide solution as polymerization solvent and activator on structural, mechanical and antibacterial properties of PNIPAAm and P (NIPAAm–clay) hydrogels. Polym Compos. 2018;39:386–406.
   Web of Science ®Google Scholar
• Şimşek C, Eroğlu ZE, Erbil C. Effect of ionomer/multiplet formation on mechanical properties and ascorbic acid release behavior of PNIPAAm hydrogels copolymerized by DMAEMA, DMAPMAAm and MAPTAC. Iran Polym J. 2019;28(11):977–990.
   Web of Science ®Google Scholar