Multi-responsive on-demand drug delivery PMMA-co-PDEAEMA platform based on CO₂, electric potential, and pH switchable nanofibrous membranes

References

• Ho J, Walsh C, Yue D, et al. Current advancements and strategies in tissue engineering for wound healing: a comprehensive review. Adv Wound Care. 2017;6(6):191–209.
   Web of Science ®Google Scholar
• Huang ZM, Zhang YZ, Kotaki M, et al. A review on polymer nanofibers by electrospinning and their applications in nanocomposites. Compos Sci Technol. 2003;63(15):2223–2253.
   Web of Science ®Google Scholar
• Schmidt S, Motschmann H, Hellweg T, et al. Thermoresponsive surfaces by spin-coating of PNIPAM-co-PAA microgels: a combined AFM and ellipsometry study. Polymer (Guildf). 2008;49(3):749–756.
   Web of Science ®Google Scholar
• Wang H, Xue Y, Lin T. One-step vapour-phase formation of patternable, electrically conductive, superamphiphobic coatings on fibrous materials. Soft Matter. 2011;7(18):8158.
   Web of Science ®Google Scholar
• Gorji M, Jeddi AAA, Gharehaghaji AA. Fabrication and characterization of polyurethane electrospun nanofiber membranes for protective clothing applications. J Appl Polym Sci. 2012;125(5):4135–4141.
   Web of Science ®Google Scholar
• Borges J, Rodrigues LC, Reis RL, et al. Layer-by-layer assembly of light-responsive polymeric multilayer systems. Adv Funct Mater. 2014;24(36):5624–5648.
   Web of Science ®Google Scholar
• Che H, Huo M, Peng L, et al. CO2-responsive nanofibrous membranes with switchable oil/water wettability. Angew Chem Int Ed. 2015;54(31):8934–8938.
   PubMed Web of Science ®Google Scholar
• Wang F, Hu S, Jia Q, et al. Advances in electrospinning of natural biomaterials for wound dressing. J Nanomater. 2020;2020:1–14.
   Web of Science ®Google Scholar
• Li Y, Wang J, Wang Y, et al. Advanced electrospun hydrogel fibers for wound healing. Compos Part B Eng. 2021;223:109101.
   Web of Science ®Google Scholar
• Alven S, Nqoro X, Aderibigbe BA. Polymer-based materials loaded with curcumin for wound healing applications. Polymers (Basel). 2020;12(10):2286.
   PubMed Web of Science ®Google Scholar
• Gizaw M, Thompson J, Faglie A, et al. Electrospun fibers as a dressing material for drug and biological agent delivery in wound healing applications. Bioengineering. 2018;5(1):9.
   PubMedGoogle Scholar
• Ranade VV, Hollinger MA, Cannon JB. Role of polymers in drug delivery. In: Drug delivery systems (3rd ed.). Boca Raton: CRC Press; 2011.
   Google Scholar
• Shi X, Zheng Y, Wang G, et al. PH- and electro-response characteristics of bacterial cellulose nanofiber/sodium alginate hybrid hydrogels for dual controlled drug delivery. RSC Adv. 2014;4(87):47056–47065.
   Web of Science ®Google Scholar
• Priya James H, John R, Alex A, et al. Smart polymers for the controlled delivery of drugs – a concise overview. Acta Pharm Sin B. 2014;4(2):120–127.
   Google Scholar
• He Q, Chen J, Yan J, et al. Tumor microenvironment responsive drug delivery systems. Asian J Pharm Sci. 2020;15(4):416–448.
   PubMed Web of Science ®Google Scholar
• Wilczewska AZ, Niemirowicz K, Markiewicz KH, et al. Nanoparticles as drug delivery systems. Pharmacol Rep. 2012;64(5):1020–1037.
   PubMed Web of Science ®Google Scholar
• Liu D, Yang F, Xiong F, et al. The smart drug delivery system and its clinical potential. Theranostics. 2016;6(9):1306–1323.
   PubMed Web of Science ®Google Scholar
• Lee SM, Nguyen ST. Smart nanoscale drug delivery platforms from stimuli-responsive polymers and liposomes. Macromolecules. 2013;46(23):9169–9180.
   PubMed Web of Science ®Google Scholar
• Shim G, Ko S, Kim D, et al. Light-switchable systems for remotely controlled drug delivery. J Control Release. 2017;267:67–79.
   PubMed Web of Science ®Google Scholar
• Aguilar M, Elvira C, Gallardo a, et al. Smart polymers and their applications as biomaterials. Top Tissue Eng. 2007;13:2–27.
   Google Scholar
• Schmaljohann D. Thermo- and pH-responsive polymers in drug delivery. Adv Drug Deliv. Rev. 2006; 58(15):1655–1670.
   PubMed Web of Science ®Google Scholar
• Bawa P, Pillay V, Choonara YE, et al. Stimuli-responsive polymers and their applications in drug delivery. Biomed Mater. 2009;4(2):022001.
   PubMed Web of Science ®Google Scholar
• Aguilar MR, San Román J. Smart polymers and their applications. Cambridge: Elsevier/Woodhead publishing; 2014;
   Google Scholar
• Wang B, Liang W, Guo Z, et al. Biomimetic super-lyophobic and super-lyophilic materials applied for oil/water separation: a new strategy beyond nature. Chem Soc Rev. 2015;44(1):336–361.
   PubMed Web of Science ®Google Scholar
• Gorji M, Mazinani S, Farokhmehr A, et al. One polymer, one layer, and two opposite functions: using a pH-switchable polymer to fabricate a hydrophilic–hydrophobic fibrous membrane. J Appl Polym Sci. 2020;137(36):49064.
   Web of Science ®Google Scholar
• Das SS, Bharadwaj P, Bilal M, et al. Stimuli-responsive polymeric nanocarriers for drug delivery, imaging, and theragnosis. Polymers (Basel). 2020;12(6):1397.
   PubMed Web of Science ®Google Scholar
• Wei P, Cornel EJ, Du J. Ultrasound-responsive polymer-based drug delivery systems. Drug Deliv Transl Res. 2021;11:1323–1339.
   PubMed Web of Science ®Google Scholar
• Amoli-Diva M, Sadighi-Bonabi R, Pourghazi K. Switchable on/off drug release from gold nanoparticles-grafted dual light- and temperature-responsive hydrogel for controlled drug delivery. Mater Sci Eng C Mater Biol Appl. 2017;76:242–248.
   PubMed Web of Science ®Google Scholar
• Varum F, Freire AC, Fadda HM, et al. A dual pH and microbiota-triggered coating (PhloralTM) for fail-safe colonic drug release. Int J Pharm. 2020;583:119379.
   PubMedGoogle Scholar
• Guo X, Mei J, Zhang C. Development of drug dual-carriers delivery system with mitochondria-targeted and pH/heat responsive capacity for synergistic photothermal-chemotherapy of ovarian cancer. Int J Nanomed. 2020;15:301–313.
   PubMed Web of Science ®Google Scholar
• Ibekwe VC, Khela MK, Evans DF, et al. A new concept in colonic drug targeting: a combined pH-responsive and bacterially-triggered drug delivery technology. Aliment Pharmacol Ther. 2008;28(7):911–916.
   PubMed Web of Science ®Google Scholar
• Tebaldi ML, Oda CMR, Monteiro LOF, et al. Biomedical nanoparticle carriers with combined thermal and magnetic response: current preclinical investigations. J Magn Magn Mater. 2018;461:116–127.
   Web of Science ®Google Scholar
• Lin S, Theato P. CO2-responsive polymers. Macromol Rapid Commun. 2013;34(14):1118–1133.
   PubMed Web of Science ®Google Scholar
• Jiang B, Zhang Y, Huang X, et al. Tailoring CO2-responsive polymers and nanohybrids for green chemistry and processes. Ind Eng Chem Res. 2019;58(33):15088–15108.
   Web of Science ®Google Scholar
• Ofridam F, Tarhini M, Lebaz N, et al. pH-sensitive polymers: classification and some fine potential applications. Polym Adv Technol. 2021;32:1455–1484.
   Web of Science ®Google Scholar
• Dehkordi TF, Shirin-Abadi AR, Karimipour K, et al. CO2-, electric potential-, and photo-switchable-hydrophilicity membrane (x-SHM) as an efficient color-changeable tool for oil/water separation. Polymer (Guildf). 2021;212:123250.
   Web of Science ®Google Scholar
• Kurzawa C, Hengstenberg A, Schuhmann W. Immobilization method for the preparation of biosensors based on pH shift-induced deposition of biomolecule-containing polymer films. Anal Chem. 2002;74(2):355–361.
   PubMed Web of Science ®Google Scholar
• Blossey R. Self-cleaning surfaces – virtual realities. Nat Mater. 2003;2:301–306.
   PubMed Web of Science ®Google Scholar
• Ma H, Hyun J, Stiller P, et al. “Non-Fouling” oligo(ethylene glycol)-functionalized polymer brushes synthesized by surface-initiated atom transfer radical polymerization. Adv Mater. 2004;16(4):338–341.
   Web of Science ®Google Scholar
• Zhang Z, Chen S, Jiang S. Dual-functional biomimetic materials: nonfouling poly(carboxybetaine) with active functional groups for protein immobilization. Biomacromolecules. 2006;7(12):3311–3315.
   PubMed Web of Science ®Google Scholar
• Bae YH. Smart polymers in drug delivery. Pharm News. 2002;9(6):417–424.
   Google Scholar
• Lipp L, Sharma D, Banerjee A, et al. In vitro and in vivo optimization of phase sensitive smart polymer for controlled delivery of rivastigmine for treatment of Alzheimer’s disease. Pharm Res. 2020;37(3):34.
   PubMed Web of Science ®Google Scholar
• Alsehli M. Polymeric nanocarriers as stimuli-responsive systems for targeted tumor (cancer) therapy: recent advances in drug delivery. Saudi Pharm J. 2020;28(3):255–265.
   PubMed Web of Science ®Google Scholar
• Xie A, Hanif S, Ouyang J, et al. Stimuli-responsive prodrug-based cancer nanomedicine. EBioMedicine. 2020;56:102821.
   PubMed Web of Science ®Google Scholar
• Li JJ, Zhu LT, Luo ZH. Electrospun fibrous membrane with enhanced swithchable oil/water wettability for oily water separation. Chem Eng J. 2016;287:474–481.
   Web of Science ®Google Scholar
• Huo Q, Zhu J, Niu Y, et al. PH-triggered surface charge-switchable polymer micelles for the co-delivery of paclitaxel/disulfiram and overcoming multidrug resistance in cancer. Int J Nanomed. 2017;12:8631–8647.
   PubMed Web of Science ®Google Scholar
• Zhang Y, Guo Q, An S, et al. ROS-Switchable polymeric nanoplatform with Stimuli-Responsive release for active targeted drug delivery to breast cancer. ACS Appl Mater Interfaces. 2017;9(14):12227–12240.
   PubMed Web of Science ®Google Scholar
• Ghani M, Heiskanen A, Kajtez J, et al. On-demand reversible UV-triggered interpenetrating polymer network-based drug delivery system using the spiropyran-merocyanine hydrophobicity switch. ACS Appl Mater Interfaces. 2021;13(3):3591–3604.
   PubMed Web of Science ®Google Scholar
• Hassanzadeh K, Buccarello L, Dragotto J, et al. Obstacles against the marketing of curcumin as a drug. Int J Mol Sci. 2020;21(18):6619.
   PubMed Web of Science ®Google Scholar
• Menon VP, Sudheer AR. Antioxidant and anti-inflammatory properties of curcumin. Adv Exp Med Biol. 2007;595:105–125.
   PubMed Web of Science ®Google Scholar
• Lee W-H, Loo C-Y, Bebawy M, et al. Curcumin and its derivatives: their application in neuropharmacology and neuroscience in the 21st century. Curr Neuropharmacol. 2013;11(4):338–378.
   PubMed Web of Science ®Google Scholar
• Howaili F, Özliseli E, Küçüktürkmen B, et al. Stimuli-responsive, plasmonic nanogel for dual delivery of curcumin and photothermal therapy for cancer treatment. Front Chem. 2020;8:602941.
   PubMed Web of Science ®Google Scholar
• Jurenka JS. Anti-inflammatory properties of curcumin, a major constituent of curcuma longa: a review of preclinical and clinical research. Altern Med Rev. 2009;14(2):141–153.
   PubMed Web of Science ®Google Scholar
• Babaei F, Nassiri-Asl M, Hosseinzadeh H. Curcumin (a constituent of turmeric): new treatment option against COVID-19. Food Sci Nutr. 2020;8(10):5215–5227.
   PubMed Web of Science ®Google Scholar
• Thimmulappa RK, Mudnakudu-Nagaraju KK, Shivamallu C, et al. Antiviral and immunomodulatory activity of curcumin: a case for prophylactic therapy for COVID-19. Heliyon. 2021;7(2):e06350.
   PubMed Web of Science ®Google Scholar
• Almeida E, Bellettini IC, Garcia FP, et al. Curcumin-loaded dual pH- and thermo-responsive magnetic microcarriers based on pectin maleate for drug delivery. Carbohydr Polym. 2017;171:259–266.
   PubMed Web of Science ®Google Scholar
• Priyadarsini KI. The chemistry of curcumin: from extraction to therapeutic agent. Molecules. 2014;19(12):20091–20112.
   PubMed Web of Science ®Google Scholar
• Schneider C, Gordon ON, Edwards RL, et al. Degradation of curcumin: from mechanism to biological implications. J Agric Food Chem. 2015;63(35):7606–7614.
   PubMed Web of Science ®Google Scholar
• Liu Q, Zhou S, Zhao Z, et al. Silk fibroin/polyethylene glycol nanofibrous membranes loaded with curcumin. Therm Sci. 2017;21(4):1587–1594.
   Web of Science ®Google Scholar
• Saber-Moghaddam N, Salari S, Hejazi S, et al. Oral nano-curcumin formulation efficacy in management of mild to moderate hospitalized coronavirus disease-19 patients: an open label nonrandomized clinical trial. Phyther Res. 2021;35:2616–2623.
   Web of Science ®Google Scholar
• Awan JA, Rehman SU, Kashif Bangash M, et al. Development and characterization of electrospun curcumin-loaded antimicrobial nanofibrous membranes. Text Res J. 2021;91(13–14):1478–1485.
   Web of Science ®Google Scholar
• Gorrasi G, Longo R, Viscusi G. Fabrication and characterization of electrospun membranes based on “poly(ε-caprolactone)”, “poly(3-hydroxybutyrate)” and their blend for tunable drug delivery of curcumin. Polymers (Basel). 2020;12(10):2239.
   PubMed Web of Science ®Google Scholar
• Omrani Z, Dadkhah Tehrani A. New cyclodextrin-based supramolecular nanocapsule for codelivery of curcumin and gallic acid. Polym Bull. 2020;77(4):2003–2019.
   Web of Science ®Google Scholar
• Sinclair SM, Bhattacharyya J, McDaniel JR, et al. A genetically engineered thermally responsive sustained release curcumin depot to treat neuroinflammation. J Control Release. 2013;171(1):38–47.
   PubMed Web of Science ®Google Scholar
• Kim S, Philippot S, Fontanay S, et al. PH- and glutathione-responsive release of curcumin from mesoporous silica nanoparticles coated using tannic acid-Fe(III) complex. RSC Adv. 2015;5(110):90550–90558.
   Web of Science ®Google Scholar
• Patil PB, Parit SB, Waifalkar PP, et al. pH triggered curcumin release and antioxidant activity of curcumin loaded γ-Fe2O3 magnetic nanoparticles. Mater Lett. 2018;223:178–181.
   Web of Science ®Google Scholar
• Shi Y, Xiong D, Li Z, et al. Highly efficient and reversible inversion of a pickering emulsion triggered by CO2/N2 at ambient conditions. ACS Sustain Chem Eng. 2018;6(11):15383–15390.
   Web of Science ®Google Scholar
• Li Z, Zhang L, Wei X, et al. Temperature/pH-responsive hexagonal liquid crystal for curcumin release. Langmuir. 2019;35(2):453–460.
   PubMed Web of Science ®Google Scholar
• Rezaee Shirin-Abadi A, Gorji M, Rezaee S, et al. CO2-Switchable-hydrophilicity membrane (CO2-SHM) triggered by electric potential: faster switching time along with efficient oil/water separation. Chem Commun. 2018;54(61):8478–8481.
   PubMed Web of Science ®Google Scholar
• Kim K, Paik SH, Rhee CK. Water Electrolysis Accompanied by Side Reactions. J Chem Educ. 2021;98(7):2381–2386.
   Google Scholar
• Yuan W, Shen J, Zou H. Amphiphilic block copolymer terminated with pyrene group: from switchable CO2-temperature dual responses to tunable fluorescence. RSC Adv. 2015;5(17):13145–13152.
   Web of Science ®Google Scholar
• Kokabi M, Sirousazar M, Hassan ZM. PVA-clay nanocomposite hydrogels for wound dressing. Eur Polym J. 2007;43(3):773–781.
   Web of Science ®Google Scholar
• Palza H, Zapata PA, Angulo-Pineda C. Electroactive smart polymers for biomedical applications. Materials (Basel). 2019;12(2):277.
   PubMed Web of Science ®Google Scholar
• Yuvaraj AL, Santhanaraj D. A systematic study on electrolytic production of hydrogen gas by using graphite as electrode. Mater Res. 2014;17(1):83–87.
   Web of Science ®Google Scholar
• Baek JS, Choo CC, Qian C, et al. Multi-drug-loaded microcapsules with controlled release for management of Parkinson’s disease. Small. 2016;12(27):3712–3722.
   PubMed Web of Science ®Google Scholar
• Wu Y, Lv S, Li Y, et al. Co-delivery of dual chemo-drugs with precisely controlled, high drug loading polymeric micelles for synergistic anti-cancer therapy. Biomater Sci. 2020;8(3):949–959.
   PubMed Web of Science ®Google Scholar
• Iacobino A, Fattorini L, Giannoni F. Drug-resistant tuberculosis 2020: where we stand. Appl Sci. 2020;10(6):2153.
   Google Scholar
• Li XY, Xie R, Luo F, et al. CO2-responsive poly(N,N-dimethylaminoethyl methacrylate) hydrogels with fast responsive rate. J Taiwan Inst Chem Eng. 2019;94:135–142.
   Web of Science ®Google Scholar
• Zhu YJ, Chen F. pH-responsive drug-delivery systems. Chem Asian J. 2015;10(2):284–305.
   PubMed Web of Science ®Google Scholar
• Roointan A, Farzanfar J, Mohammadi-Samani S, et al. Smart pH responsive drug delivery system based on poly(HEMA-co-DMAEMA) nanohydrogel. Int J Pharm. 2018;552(1–2):301–311.
   PubMedGoogle Scholar
• Gabriel LP, Rodrigues AA, Macedo M, et al. Electrospun polyurethane membranes for tissue engineering applications. Mater Sci Eng C Mater Biol Appl. 2017;72:113–117.
   PubMed Web of Science ®Google Scholar
• Xing X, Cheng G, Yin C, et al. Magnesium-containing silk fibroin/polycaprolactone electrospun nanofibrous scaffolds for accelerating bone regeneration. Arab J Chem. 2020;13(5):5526–5538.
   Web of Science ®Google Scholar
• Rethinam S, Basaran B, Vijayan S, et al. Electrospun nano-bio membrane for bone tissue engineering application – a new approach. Mater Chem Phys. 2020;249:123010.
   Web of Science ®Google Scholar
• Dhinasekaran D, Vimalraj S, Rajendran AR, et al. Bio-inspired multifunctional collagen/electrospun bioactive glass membranes for bone tissue engineering applications. Mater Sci Eng C Mater Biol Appl. 2021;126:111856.
   PubMed Web of Science ®Google Scholar
• Kangwansupamonkon W, Lauruengtana V, Surassmo S, et al. Antibacterial effect of apatite-coated titanium dioxide for textiles applications. Nanomed Nanotechnol Biol Med. 2009;5(2):240–249.
   PubMed Web of Science ®Google Scholar
• Tyagi P, Singh M, Kumari H, et al. Bactericidal activity of curcumin I is associated with damaging of bacterial membrane. PLoS One. 2015;10(3):e0121313.
   PubMed Web of Science ®Google Scholar
• Zheng D, Huang C, Huang H, et al. Antibacterial mechanism of curcumin: a review. Chem Biodivers. 2020;17(8):e2000171.
   PubMed Web of Science ®Google Scholar