Lysine and citric acid based pegylated polymeric dendritic nano drug delivery carrier and their bioactivity evaluation

References

• Svenson S. Dendrimers as versatile platform in drug delivery applications. Eur J Pharm Biopharm. 2009;71(3):445–462. doi: 10.1016/j.ejpb.2008.09.023.
   PubMed Web of Science ®Google Scholar
• Verma RK, Garg S. Drug delivery technologies and future directions. Pharm Technol. 2001;25(2):1–14.
   Google Scholar
• Adepu S, Ramakrishna S. Controlled drug delivery systems: current status and future directions. Molecules. 2021;26(19):5905. doi: 10.3390/molecules26195905.
   PubMed Web of Science ®Google Scholar
• Park K. Controlled drug delivery systems: past forward and future back. J Controlled Release. 2014;190:3–8.
   PubMed Web of Science ®Google Scholar
• Wang J, Li B, Qiu L, et al. Dendrimer-based drug delivery systems: history, challenges, and latest developments. J Biol Eng. 2022;16(1):18. doi: 10.1186/s13036-022-00298-5.
   PubMed Web of Science ®Google Scholar
• Nguyen CK, Tran NQ, Nguyen TP, et al. Biocompatible nanomaterials based on dendrimers, hydrogels and hydrogel nanocomposites for use in biomedicine. Adv Nat Sci Nanosci Nanotechnol. 2017;8(1):015001.
   Google Scholar
• Nikzamir M, Hanifehpour Y, Akbarzadeh A, et al. Applications of dendrimers in nanomedicine and drug delivery: a review. J Inorg Organomet Polym. 2021;31(6):2246–2261. doi: 10.1007/s10904-021-01925-2.
   Web of Science ®Google Scholar
• Tian B, Hua S, Tian Y, et al. Chemical and physical chitosan hydrogels as prospective carriers for drug delivery: a review. J Mater Chem B. 2020;8(44):10050–10064. doi: 10.1039/d0tb01869d.
   PubMed Web of Science ®Google Scholar
• Dhull A, Yu C, Wilmoth AH, et al. Dendrimers in corneal drug delivery: recent developments and translational opportunities. Pharmaceutics. 2023;15(6):1591. doi: 10.3390/pharmaceutics15061591.
   PubMed Web of Science ®Google Scholar
• Patel V, Rajani C, Paul D, et al. Dendrimers as novel drug-delivery system and its applications. In: Drug delivery systems. Chennai, India: Elsevier; 2020. p. 333–392.
   Google Scholar
• Gauro R, Nandave M, Jain VK, et al. Advances in dendrimer-mediated targeted drug delivery to the brain. J Nanoparticle Res. 2021;23:1–20.
   Web of Science ®Google Scholar
• Mukherjee S, Mukherjee S, Abourehab MA, et al. Exploring dendrimer-based drug delivery systems and their potential applications in cancer immunotherapy. Eur Polym J. 2022;177:111471.
   Web of Science ®Google Scholar
• Ali Y, Alqudah A, Ahmad S, et al. Macromolecules as targeted drugs delivery vehicles: an overview. Des Monomers Polym. 2019;22(1):91–97. doi: 10.1080/15685551.2019.1591681.
   PubMed Web of Science ®Google Scholar
• Ma M, Liu Y, Chang H, et al. Investigation of the binding behavior of PAMAMs-NH2 dendrimers with ofloxacin via NMR studies. Colloids Surf Physicochem Eng Asp. 2023;658:130625.
   Web of Science ®Google Scholar
• Liu M, Fréchet JM. Designing dendrimers for drug delivery. Pharm Sci Technol Today. 1999;2(10):393–401. doi: 10.1016/s1461-5347(99)00203-5.
   PubMedGoogle Scholar
• Kesharwani P, Tekade RK, Jain NK. Generation dependent cancer targeting potential of poly (propyleneimine) dendrimer. Biomaterials. 2014;35(21):5539–5548. doi: 10.1016/j.biomaterials.2014.03.064.
   PubMed Web of Science ®Google Scholar
• Huang D, Wu D. Biodegradable dendrimers for drug delivery. Mater Sci Eng C. 2018;90:713–727.
   PubMed Web of Science ®Google Scholar
• Maiti PK, Çaǧın T, Wang G, et al. Structure of PAMAM dendrimers: generations 1 through 11. Macromolecules. 2004;37(16):6236–6254. doi: 10.1021/ma035629b.
   Web of Science ®Google Scholar
• Araújo RV, de Santos SdS, Igne Ferreira E, et al. New advances in general biomedical applications of PAMAM dendrimers. Molecules. 2018;23(11):2849. doi: 10.3390/molecules23112849.
   PubMed Web of Science ®Google Scholar
• Kaur D, Jain K, Mehra NK, et al. A review on comparative study of PPI and PAMAM dendrimers. J Nanoparticle Res. 2016;18:1–14.
   Web of Science ®Google Scholar
• Gupta V, Nayak SK. Dendrimers: a review on synthetic approaches. J Appl Pharm Sci. 2015;5(3):117–122.
   Google Scholar
• Baig T, Nayak J, Dwivedi V, et al. A review about dendrimers: synthesis, types, characterization and applications. Int J Adv Pharm Biol Chem. 2015;4(1):44–59.
   Google Scholar
• Cheng Y, Qu H, Ma M, et al. Polyamidoamine (PAMAM) dendrimers as biocompatible carriers of quinolone antimicrobials: an in vitro study. Eur J Med Chem. 2007;42(7):1032–1038.
   PubMed Web of Science ®Google Scholar
• Cheng Y, Wang J, Rao T, et al. Pharmaceutical applications of dendrimers: promising nanocarriers for drug delivery. Front Biosci. 2008;13(13):1447–1471. doi: 10.2741/2774.
   PubMedGoogle Scholar
• Reymond JL. Peptide dendrimers: from enzyme models to antimicrobials and transfection reagents. Chimia (Aarau). 2021;75(6):535–538. doi: 10.2533/chimia.2021.535.
   PubMed Web of Science ®Google Scholar
• Bonvin E, Personne H, Paschoud T, et al. Antimicrobial peptide–peptoid hybrids with and without membrane disruption. ACS Infect Dis. 2023;9(12):2593–2606. doi: 10.1021/acsinfecdis.3c00421.
   PubMed Web of Science ®Google Scholar
• Patrulea V, Gan B-H, Perron K, et al. Synergistic effects of antimicrobial peptide dendrimer-chitosan polymer conjugates against Pseudomonas aeruginosa. Carbohydr Polym. 2022;280:119025. doi: 10.1016/j.carbpol.2021.119025.
   PubMed Web of Science ®Google Scholar
• Al Hagbani T, Rizvi SM, Hussain T, et al. Cefotaxime mediated synthesis of gold nanoparticles: Characterization and antibacterial activity. Polymers. 2022;14(4):771.
   Google Scholar
• Jones SR, Levinson W, Kimbrough RC, Ditmer-Schutz D. The use of cefotaxime in a community hospital. Drug Intell Clin Pharm. 1984;18(2):144–147. doi:10.1177/106002808401800211.
   Google Scholar
• Javaid S, Ahmad NM, Mahmood A, et al. Cefotaxime loaded polycaprolactone based polymeric nanoparticles with antifouling properties for in-vitro drug release applications. Polymers (Basel). 2021;13(13):2180. doi: 10.3390/polym13132180.
   PubMed Web of Science ®Google Scholar
• Narayanan P, Anitha AK, Ajayakumar N, et al. Poly-lysine dendritic nanocarrier to target epidermal growth factor receptor overexpressed breast cancer for methotrexate delivery. Materials. 2022;15(3):800. doi: 10.3390/ma15030800.
   PubMed Web of Science ®Google Scholar
• Kaminskas LM, Kelly BD, McLeod VM, et al. Pharmacokinetics and tumor disposition of PEGylated, methotrexate conjugated poly- l -lysine dendrimers. Mol Pharm. 2009;6(4):1190–1204.
   PubMed Web of Science ®Google Scholar
• Luong D, Kesharwani P, Deshmukh R, et al. PEGylated PAMAM dendrimers: enhancing efficacy and mitigating toxicity for effective anticancer drug and gene delivery. Acta Biomater. 2016;43:14–29. doi: 10.1016/j.actbio.2016.07.015.
   PubMed Web of Science ®Google Scholar
• Athanasiou V, Thimi P, Liakopoulou M, et al. Synthesis and characterization of the novel Nε-9-fluorenylmethoxycarbonyl-l-lysine N-carboxy anhydride. Synthesis of well-defined linear and branched polypeptides. Polymers (Basel). 2020;12(12):2819. doi: 10.3390/polym12122819.
   PubMed Web of Science ®Google Scholar
• Garg T, Singh O, Arora S, et al. Dendrimer-a novel scaffold for drug delivery. Int J Pharm Sci Rev Res. 2011;7(2):211–220.
   Google Scholar
• Mohammadzadeh P, Shafiee Ardestani M, Mortazavi-Derazkola S, et al. Peg-citrate dendrimer second generation: is this a good carrier for imaging agents in vitro and in vivo? IET Nanobiotechnol. 2019;13(6):560–564. doi: 10.1049/iet-nbt.2018.5360.
   PubMed Web of Science ®Google Scholar
• Salehi A, Behpour M, Afzali D. PEG-mesoporous material modified by superparamagnetic nanoparticles as a delivery system of cefotaxime. Arch Microbiol. 2022;204(6):322. doi: 10.1007/s00203-022-02937-3.
   PubMed Web of Science ®Google Scholar
• Valikala V, Santhakumar I, Kannappan S. Synthesis and effect of pegylation on citric acid dendritic nano architectures anchored with cefotaxime sodium. J Photochem Photobiol B. 2019;201:111683. doi: 10.1016/j.jphotobiol.2019.111683.
   PubMed Web of Science ®Google Scholar
• Kumar S, Randhawa JK. Preparation and characterization of paliperidone loaded solid lipid nanoparticles. Colloids Surf B Biointerfaces. 2013;102:562–568. doi: 10.1016/j.colsurfb.2012.08.052.
   PubMed Web of Science ®Google Scholar
• Liu B, Li M, Zhao Y, et al. A sensitive electrochemical immunosensor based on PAMAM dendrimer-encapsulated Au for detection of norfloxacin in animal-derived foods. Sensors. 2018;18(6):1946. doi: 10.3390/s18061946.
   PubMed Web of Science ®Google Scholar
• Peng Z, Li H, Ba X, et al. Synthesis of TiO2 nanoparticles in the PAMAM hydrogen network template. E-Polym. 2016;16(3):177–180. doi: 10.1515/epoly-2015-0277.
   Web of Science ®Google Scholar
• Jahromi LP, Ghazali M, Ashrafi H, et al. A comparison of models for the analysis of the kinetics of drug release from PLGA-based nanoparticles. Heliyon. 2020;6(2):e03451. doi: 10.1016/j.heliyon.2020.e03451.
   PubMed Web of Science ®Google Scholar
• Singhvi G, Singh M. In-vitro drug release characterization models. Int J Pharm Stud Res. 2011;2(1):77–84.
   Google Scholar
• Permanadewi I, Kumoro AC, Wardhani DH, et al. Modelling of controlled drug release in gastrointestinal tract simulation. J Phys Conf Ser. 2019;1295(1):012063. Available from: https://iopscience.iop.org/article/. doi: 10.1088/1742-6596/1295/1/012063/meta.
   Google Scholar
• Wojcik-Pastuszka D, Krzak J, Macikowski B, et al. Evaluation of the release kinetics of a pharmacologically active substance from model intra-articular implants replacing the cruciate ligaments of the knee. Materials. 2019;12(8):1202. doi: 10.3390/ma12081202.
   PubMed Web of Science ®Google Scholar
• Chandra S, Dietrich S, Lang H, et al. Dendrimer–doxorubicin conjugate for enhanced therapeutic effects for cancer. J Mater Chem. 2011;21(15):5729–5737.
   Web of Science ®Google Scholar
• Walia S, Mukhia S, Bhatt V, et al. Variability in chemical composition and antimicrobial activity of tagetes minuta L. essential oil collected from different locations of himalaya. Ind Crops Prod. 2020;150:112449.
   Web of Science ®Google Scholar
• Kaundal R, Kumar M, Kumar S, et al. Polyphenolic profiling, antioxidant, and antimicrobial activities revealed the quality and adaptive behavior of viola species, a dietary spice in the himalayas. Molecules. 2022;27(12):3867. doi: 10.3390/molecules27123867.
   PubMed Web of Science ®Google Scholar
• Kapoor S, Padwad YS. Phloretin induces G2/M arrest and apoptosis by suppressing the β-catenin signaling pathway in colorectal carcinoma cells. Apoptosis. 2023;28(5-6):810–829. doi: 10.1007/s10495-023-01826-4.
   PubMed Web of Science ®Google Scholar
• Wang W, Xiong W, Zhu Y, et al. Protective effect of PEGylation against poly (amidoamine) dendrimer-induced hemolysis of human red blood cells. J Biomed Mater Res. 2010;93B(1):59–64. doi: 10.1002/jbm.b.31558.
   Web of Science ®Google Scholar
• Lee CC, Tsai WS, Hsieh HJ, et al. Hemolytic activity of venom from crown-of-thorns starfish acanthaster planci spines. J Venom Anim Toxins Trop Dis. 2013;19:1–8.
   PubMed Web of Science ®Google Scholar
• Bodewein L, Schmelter F, Di Fiore S, et al. Differences in toxicity of anionic and cationic PAMAM and PPI dendrimers in zebrafish embryos and cancer cell lines. Toxicol Appl Pharmacol. 2016;305:83–92. doi: 10.1016/j.taap.2016.06.008.
   PubMed Web of Science ®Google Scholar
• Janaszewska A, Lazniewska J, Trzepiński P, et al. Cytotoxicity of dendrimers. Biomolecules. 2019;9(8):330. doi: 10.3390/biom9080330.
   PubMed Web of Science ®Google Scholar