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Research Article

Temporal modulation of inflammation and chondrogenesis through dendritic nanoparticle-mediated therapy with diclofenac surface modification and strontium ion encapsulation

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Received 20 Sep 2023, Accepted 05 Jun 2024, Published online: 12 Jul 2024

References

  • Gao W, Chen K, He W, et al. Synergistic chondrogenesis promotion and arthroscopic articular cartilage restoration via injectable dual-drug-loaded sulfated hyaluronic acid hydrogel for stem cell therapy. Compos B Eng. 2023;263:110857. doi: 10.1016/j.compositesb.2023.110857.
  • Xu Y, Duan H, Li YQ, et al. Nanofibrillar decellularized Wharton’s jelly matrix for segmental tracheal repair. Adv Funct Mater. 2020;30(14):1910067.
  • Xu Y, Guo Y, Li Y, et al. Biomimetic trachea regeneration using a modular ring strategy based on poly(sebacoyl diglyceride)/polycaprolactone for segmental trachea defect repair. Adv Funct Mater. 2020;30(42):2004276. doi: 10.1002/adfm.202004276.
  • Gao E, Li G, Cao RF, et al. Bionic tracheal tissue regeneration using a ring-shaped scaffold comprised of decellularized cartilaginous matrix and silk fibroin. Compos B Eng. 2022;229:109470.
  • Su C, Lin D, Huang X, et al. Developing hydrogels for gene therapy and tissue engineering. J Nanobiotechnol. 2024;22(1):182. doi: 10.1186/s12951-024-02462-z.
  • Wang YH, Xu Y, Zhou GD, et al. Biological evaluation of acellular cartilaginous and dermal matrixes as tissue engineering scaffolds for cartilage regeneration. Front Cell Dev Biol. 2020;8:624337.
  • Zhou H, Zhang Y, Zhang R, et al. A tumor-microenvironment-activatable molecular pro-theranostic agent for photodynamic and immunotherapy of cancer. Adv Mater. 2023;35(30):e2211485. doi: 10.1002/adma.202211485.
  • Li Y, Liang Q, Zhou L, et al. An ROS-responsive artesunate prodrug nanosystem co-delivers dexamethasone for rheumatoid arthritis treatment through the HIF-1α/NF-κB cascade regulation of ROS scavenging and macrophage repolarization. Acta Biomater. 2022;152:406–424. doi: 10.1016/j.actbio.2022.08.054.
  • Li M, Yin H, Yan Z, et al. The immune microenvironment in cartilage injury and repair. Acta Biomater. 2022;140:23–42. doi: 10.1016/j.actbio.2021.12.006.
  • Cai Z, Li Y, Song W, et al. Anti-inflammatory and prochondrogenic in situ-formed injectable hydrogel crosslinked by strontium-doped bioglass for cartilage regeneration. ACS Appl Mater Interfaces. 2021;13(50):59772–59786. doi: 10.1021/acsami.1c20565.
  • Yang ML, Sun WY, Wang L, et al. Curcumin loaded polycaprolactone scaffold capable of anti-inflammation to enhance tracheal cartilage regeneration. Mater Des. 2022;224:111299.
  • Li X, Chen W, Liu D, et al. Pathological progression of osteoarthritis: a perspective on subchondral bone. Front Med. 2024;18(2):237–257. doi: 10.1007/s11684-024-1061-y.
  • Calderon-Ospina CA, Nava-Mesa MO, Arbeláez Ariza CE. Effect of combined diclofenac and B vitamins (thiamine, pyridoxine, and cyanocobalamin) for low back pain management: systematic review and meta-analysis. Pain Med. 2020;21(4):766–781. doi: 10.1093/pm/pnz216.
  • Kawase A, Takashima O, Tanaka S, et al. Diclofenac-induced cytotoxicity in direct and indirect co-culture of HepG2 cells with differentiated THP-1 cells. Int J Mol Sci. 2022;23(15):8660. doi: 10.3390/ijms23158660.
  • Schmidt S, Klampfleuthner FAM, Renkawitz T, et al. Cause and chondroprotective effects of prostaglandin E2 secretion during mesenchymal stromal cell chondrogenesis. Eur J Cell Biol. 2024;103(2):151412. doi: 10.1016/j.ejcb.2024.151412.
  • Li Y, Xiao J, Dong H, et al. Enhanced chalcopyrite-catalyzed heterogeneous Fenton oxidation of diclofenac by ABTS. J Hazard Mater. 2024;463:132908. doi: 10.1016/j.jhazmat.2023.132908.
  • Bonkovsky HL, Ghabril M, Nicoletti P, et al. Drug-induced liver injury (DILI) ascribed to non-steroidal anti-inflammatory drugs (NSAIDs) in the USA-update with genetic correlations. Liver Int. 2024;44(6):1409–1421.
  • Xu L, Ma F, Huang J, et al. Metformin hydrochloride encapsulation by alginate strontium hydrogel for cartilage regeneration by reliving cellular senescence. Biomacromolecules. 2021;22(2):671–680. doi: 10.1021/acs.biomac.0c01488.
  • Lu W, Zhou Y, Yang H, et al. Efficacy of strontium supplementation on implant osseointegration under osteoporotic conditions: a systematic review. J Prosthet Dent. 2022;128(3):341–349. doi: 10.1016/j.prosdent.2020.12.031.
  • Salamanna F, Giavaresi G, Contartese D, et al. Effect of strontium substituted ß-TCP associated to mesenchymal stem cells from bone marrow and adipose tissue on spinal fusion in healthy and ovariectomized rat. J Cell Physiol. 2019;234(11):20046–20056. doi: 10.1002/jcp.28601.
  • Xu G, Zhang J, Qi M, et al. Thermoresponsive dendritic oligoethylene glycols. Phys Chem Chem Phys. 2022;24(19):11848–11855. doi: 10.1039/d2cp01286c.
  • Wong KH, Guo Z, Law MK, et al. Functionalized PAMAM constructed nanosystems for biomacromolecule delivery. Biomater Sci. 2023;11(5):1589–1606. doi: 10.1039/d2bm01677j.
  • Liu YH, Wang LR, Liu Z, et al. Durable immunomodulatory nanofiber niche for the functional remodeling of cardiovascular tissue. ACS Nano. 2023;18(1):951–971. doi: 10.1021/acsnano.3c09692.
  • Hao Z, Chen T, Wang Y, et al. Self-assembling peptide nanofibers anchored parathyroid hormone derivative for bone tissue engineering. Adv Fiber Mater. 2024;6(2):583–606. doi: 10.1007/s42765-023-00370-9.
  • Xu Y, Wang Z, Hua Y, et al. Photocrosslinked natural hydrogel composed of hyaluronic acid and gelatin enhances cartilage regeneration of decellularized trachea matrix. Mater Sci Eng C Mater Biol Appl. 2021;120:111628. doi: 10.1016/j.msec.2020.111628.
  • Gao ER, Wang Y, Wang PL, et al. C-shaped cartilage development using Wharton’s jelly-derived hydrogels to assemble a highly biomimetic neotrachea for use in circumferential tracheal reconstruction. Adv Funct Mater. 2023;33(14):2212830.
  • Zhang Y, Cai R, Li J, et al. The immunosuppressive niche established with a curcumin-loaded electrospun nanofibrous membrane promotes cartilage regeneration in immunocompetent animals. Membranes (Basel). 2023;13(3):335. doi: 10.3390/membranes13030335.
  • Nedunchezhiyan U, Varughese I, Sun AR, et al. Obesity, inflammation, and immune system in osteoarthritis. Front Immunol. 2022;13:907750. doi: 10.3389/fimmu.2022.907750.
  • Xu S, Zhao S, Jian Y, et al. Icariin-loaded hydrogel with concurrent chondrogenesis and anti-inflammatory properties for promoting cartilage regeneration in a large animal model. Front Cell Dev Biol. 2022;10:1011260. doi: 10.3389/fcell.2022.1011260.
  • Wu CL, Harasymowicz NS, Klimak MA, et al. The role of macrophages in osteoarthritis and cartilage repair. Osteoarthritis Cartilage. 2020;28(5):544–554. doi: 10.1016/j.joca.2019.12.007.
  • Sha’ban M, Ahmad Radzi MA. Scaffolds for cartilage regeneration: to use or not to use? Adv Exp Med Biol. 2020;1249:97–114. doi: 10.1007/978-981-15-3258-0_7.
  • Thomas CN, Mavrommatis S, Schroder LK, et al. An overview of 3D printing and the orthopaedic application of patient-specific models in malunion surgery. Injury. 2022;53(3):977–983. doi: 10.1016/j.injury.2021.11.019.
  • Song H, Park KH. Regulation and function of SOX9 during cartilage development and regeneration. Semin Cancer Biol. 2020;67(Pt 1):12–23. doi: 10.1016/j.semcancer.2020.04.008.
  • Dong X, Li C, Zhang M, et al. Multifunctional injectable hydrogel for effective promotion of cartilage regeneration and protection against osteoarthritis: combined chondroinductive, antioxidative and anti-inflammatory strategy. Sci Technol Adv Mater. 2022;23(1):361–375. doi: 10.1080/14686996.2022.2076568.
  • Chen C, Huang S, Chen Z, et al. Kartogenin (KGN)/synthetic melanin nanoparticles (SMNP) loaded theranostic hydrogel scaffold system for multiparametric magnetic resonance imaging guided cartilage regeneration. Bioeng Transl Med. 2023;8(1):e10364. doi: 10.1002/btm2.10364.
  • Yu C, Shi M, He S, et al. Chronological adhesive cardiac patch for synchronous mechanophysiological monitoring and electrocoupling therapy. Nat Commun. 2023;14(1):6226. doi: 10.1038/s41467-023-42008-9.
  • Zhan AQ, Chen L, Sun W, et al. Enhancement of diabetic wound healing using a core-shell nanofiber platform with sequential antibacterial, angiogenic, and collagen deposition activities. Mater Des. 2022;218:110660.
  • He W, Li C, Zhao S, et al. Integrating coaxial electrospinning and 3D printing technologies for the development of biphasic porous scaffolds enabling spatiotemporal control in tumor ablation and osteochondral regeneration. Bioact Mater. 2024;34:338–353.
  • Wang B, Fei X, Yin HF, et al. Photothermal-controllable microneedles with antitumor, antioxidant, angiogenic, and chondrogenic activities to sequential eliminate tracheal neoplasm and reconstruct tracheal cartilage. Small. 2023;20(11):e2309454. doi: 10.1002/smll.202309454.
  • Banihani SA. Effect of diclofenac on semen quality: a review. Andrologia. 2021;53(5):e14021. doi: 10.1111/and.14021.
  • Hu P, Du J, Zhang S, et al. Oral administration of strontium gluconate effectively reduces articular cartilage degeneration through enhanced anabolic activity of chondrocytes and chondrogenetic differentiation of mesenchymal stromal cells. Biol Trace Elem Res. 2020;193(2):422–433. doi: 10.1007/s12011-019-01711-9.
  • Deng C, Zhu H, Li J, et al. Bioactive scaffolds for regeneration of cartilage and subchondral bone interface. Theranostics. 2018;8(7):1940–1955. doi: 10.7150/thno.23674.
  • Surekha B, Kommana NS, Dubey SK, et al. PAMAM dendrimer as a talented multifunctional biomimetic nanocarrier for cancer diagnosis and therapy. Colloids Surf B Biointerfaces. 2021;204:111837. doi: 10.1016/j.colsurfb.2021.111837.
  • Kurian AG, Singh RK, Patel KD, et al. Multifunctional GelMA platforms with nanomaterials for advanced tissue therapeutics. Bioact Mater. 2022;8:267–295. doi: 10.1016/j.bioactmat.2021.06.027.
  • Bai B, Hou M, Hao J, et al. Research progress in seed cells for cartilage tissue engineering. Regen Med. 2022;17(9):659–675. doi: 10.2217/rme-2022-0023.
  • Xu Y, Dai J, Zhu X, et al. Biomimetic trachea engineering via a modular ring strategy based on bone-marrow stem cells and atelocollagen for use in extensive tracheal reconstruction. Adv Mater. 2022;34(6):e2106755.

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