Ocular Self-Microemulsifying Drug Delivery System of Prednisolone Improves Therapeutic Effectiveness in the Treatment of Experimental Uveitis

References

• Li N, Zhuang C, Wang M, et al. Liposome coated with low molecular weight chitosan and its potential use in ocular drug delivery. Int J Pharm. 2009;379:131–138.
   PubMed Web of Science ®Google Scholar
• Maurice DM. Kinetics of topically applied drugs in ophthalmic drug delivery: Biopharmaceutical, technological and clinical aspects. In: Saettone MS, Bucci P, Speiser P, eds. Fidia Research Series. Padova: Liviana Press;1987:11:19–26.
   Google Scholar
• Sanchez A, Alonso MJ. Nanoparticulate carriers for ocular drug delivery. – In: Torchilin VP, ed., Nanoparticulate as Drug Carriers. Imperial College Press;2006:650–668.
   Google Scholar
• Balasubramaniam J, Kant S, Pandit JK. In vitro and in vivo evaluation of the Gelrite® gellan gum-based ocular delivery system for indomethacin. Acta Pharm. 2003;53:251–261.
   PubMedGoogle Scholar
• Zhang P, Liu X, Hu W, et al. Preparation and evaluation of naringenin-loaded sulfobutylether: Cyclodextrin/chitosan nanoparticles for ocular drug delivery. Carbohyd Polym. 2016;149:224–230.
   PubMed Web of Science ®Google Scholar
• de Sá FA, Taveira SF, Gelfuso GM, et al. Liposomal voriconazole (VOR) formulation for improved ocular delivery. Colloids Surf B. 2015;133:331–338.
   PubMed Web of Science ®Google Scholar
• Ramazani F, Hiemstra C, Steendam R, et al. Sunitinib microspheres based on [PDLLA-PEG-PDLLA]-b-PLLA multi-block copolymers for ocular drug delivery. Eur J Pharm. Biopharm. 2015; 95:368–377. doi: 10.1016/j.ejpb.2015.02.011
   PubMed Web of Science ®Google Scholar
• Ambhore NP, Dandagi PM, Gadad AP. Formulation and comparative evaluation of HPMC and water soluble chitosan-based sparfloxacin nanosuspension for ophthalmic delivery. Drug Deliv Transl Res. 2016; 6:48–56. doi:10.1007/s13346-015-0262-y
   PubMed Web of Science ®Google Scholar
• ElKasabgy NA, Ocular supersaturated self-nanoemulsifying drug delivery systems (S-SNEDDS) to enhance econazole nitrate bioavailability. Int J Pharm. 2014;35:269–276.
   Google Scholar
• Bharti SK, Kesavan K. Phase transition W/O microemulsions for ocular delivery. evaluation of antibacterial activity in the treatment of bacterial keratitis. Ocul Immunol Inflamm. 2016. ( In press). doi:10.3109/09273948.2016.1139136
   PubMed Web of Science ®Google Scholar
• Wakerly MG, Pouton CW, Meakin BJ, et al. Self emulsification of vegetable oil-non-ionic surfactant mixtures. ACS Symp Series. 1986;55:242.
   Google Scholar
• Constantinides PP. Lipid microemulsions for improving drug dissolution and oral absorption: Physical and biopharmaceutical aspects. Pharm Res. 1995;12:1561–1572.
   PubMed Web of Science ®Google Scholar
• Lipinski C. Poor aqueous solubility: An industry wide problem in drug discovery. Am Pharm Rev. 2002;5:82–85.
   Google Scholar
• Palmer AM, New horizons in drug metabolism, pharmacokinetics and drug discovery. Drug News Perspect. 2003;16:57–62.
   PubMedGoogle Scholar
• Charman WN, Stella VJ. Transport of lipophilic molecules by the intestinal lymphatic system. Adv Drug Del Rev. 1991;7:1–14.
   Web of Science ®Google Scholar
• Kommuru TR, Gurley B, Khan, MA, et al. Self-emulsifying drug delivery systems (SEDDS) of coenzyme Q10: Formulation development and bioavailability assessment. Int J Pharm. 2001;212:233–246.
   PubMed Web of Science ®Google Scholar
• O’Connor GR. Behcet’s disease. In: Ktein EA, ed. Symposium on Medical and Surgical Diseases of the Retina and Vitreous. St. Louis: C.V. Mosby Co;1983.
   Google Scholar
• Forster D. General approach to the uveitis patient and treatment strategies. In: Yanoff M, Ducker J, eds. Ophthalmology. St. Louis: Mosby;2004:2:1115–1120.
   Google Scholar
• Tranoudis I, Efron N. Parameter stability of soft contact lenses made from different materials. Cont Lens Anterior Eye. 2004;27:115–131.
   PubMedGoogle Scholar
• Sindt CW, Longmuir RA. Contact lens strategies for the patient with dry eye. Ocul Surf. 2007;5:294–307.
   PubMed Web of Science ®Google Scholar
• Talegaonkar S, Azeem A, Ahmad FJ, Khar, et al. Microemulsions: A novel approach to enhanced drug delivery. Recent Pat Drug Deliv Formul. 2008;2:238–257.
   PubMedGoogle Scholar
• Ghosh PK, Murthy RSR. Microemulsions: A potential drug delivery system. Curr Drug Deliv. 2006;3:167–180.
   PubMedGoogle Scholar
• Aragona P, Bucolo C, Spinella R. Systemic omega-6 fatty acid treatment and PGE1 tear content in Sjogren’s patients. Invest Ophthalmol Vis Sci. 2005;46:4474–4479.
   PubMed Web of Science ®Google Scholar
• Gursoy RN, Benita S. Self-emulsifying drug delivery systems (SEDDS) for improved oral delivery of lipophilic drugs. Biomed Pharmacother. 2004;58:173–182.
   PubMed Web of Science ®Google Scholar
• Grant WM, Schuman JS. Toxicology of the Eye, 4th edn. Springfield, IL: Charles C Thomas;1993:282–283, and 842–843.
   Google Scholar
• Kesavan K, Shri Kant, Singh PN, et al. Mucoadhesive chitosan coated cationic microemulsion of dexamethasone for ocular delivery: In vitro and in vivo evaluation. Curr Eye Res. 2013;8(3):342–352.
   Google Scholar
• Cui J, Yu B, Zhao Y, et al. Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems. Int J Pharm. 2009;371:148–155.
   PubMed Web of Science ®Google Scholar
• Zhang P, Liu Y, Feng N, et al. Preparation and evaluation of self-microemulsifying drug delivery system of oridonin. Int J Pharm. 2008;355:269–276.
   PubMed Web of Science ®Google Scholar
• Babita K, Kesavan K. Effect of chitosan coating on microemulsion for effective dermal clotrimazole delivery. Pharm Dev Technol. 2016; 22:617–626. doi:10.1080/10837450.2016.1230629
   Web of Science ®Google Scholar
• Chen Y, Li G, Wu XG, et al. Selfmicroemulsifying drug delivery system (SMEDDS) of vinpocetine: Formulation development and in vivo assessment. Biol Pharm Bull. 2008;31:118–125.
   PubMed Web of Science ®Google Scholar
• Holm R, Jensen IHM, Sonnergaard J. Optimization of self-microemulsifying drug delivery systems (SMEDDS) using a D-optimal design and the desirability function. Drug Dev Ind Pharm. 2006;32:1025–1032.
   PubMed Web of Science ®Google Scholar
• Basalious EB, Shawky N, Badr-Eldin SM. SNEDDS containing bioenhancers for improvement of dissolution and oral absorption of lacidipine. I: Development and optimization. Int J Pharm. 2010;391:203–211.
   PubMed Web of Science ®Google Scholar
• Kesavan K, Shri Kant, Pandit JK, et al. Positively charged microemulsions of dexamethasone: Comparative effects of two cosurfactants on ocular drug delivery and bioavailability. Ther Deliv. 2013;4(11):1385–1395.
   PubMedGoogle Scholar
• Kesavan K, Shri Kant, Singh PN, et al. Effect of Hydroxypropyl-β-cyclodextrin on the ocular bioavailability of dexamethasone from a pH induced mucoadhesive hydrogel. Curr Eye Res. 2011;36:918–929.
   PubMed Web of Science ®Google Scholar
• Kesavan K, Nath G, Pandit JK. Sodium alginate based mucoadhesive system for gatifloxacin and its in vitro antibacterial activity. Sci Pharm. 2010;78:941–957.
   PubMedGoogle Scholar
• Higuchi T. Mechanism of sustained action medication: theoretical analysis of rate of release of solid drugs dispersed in solid matrices. J Pharm Sci. 1963;52:1145–1149.
   PubMed Web of Science ®Google Scholar
• Driaze JH, Woodard G, Calvey HO. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J Pharmacol Exp Ther. 1944;81:377–390.
   Google Scholar
• Kesavan K, Shri Kant, Singh PN, et al. Therapeutic effectiveness in the treatment of experimental bacterial keratitis with ion-activated mucoadhesive hydrogel. Ocul Immunol Inflamm. 2016;24(5):489–492.
   PubMed Web of Science ®Google Scholar
• Craig DQM. The use of self-emulsifying systems as a means of improving drug delivery. B T Gattefosse. 1995;86:21–31.
   Google Scholar
• Nepal PR, Han HK, Choi HK. Preparation and in vitro-in vivo evaluation ofWitepsol H35 based self-nanoemulsifying drug delivery systems (SNEDDS) ofcoenzyme Q (10). Eur J Pharm Sci. 2010;39:224–232.
   PubMed Web of Science ®Google Scholar
• Tripathi A, Gupta R, Saraf SA. PLGA nanoparticles of anti tubercular drug: Drug loading and release studies of a water-insoluble drug. Int J Pharm Tech Res. 2010;2:2116–2123.
   Google Scholar
• Balakrishnan P, Lee BJ, Oh DH, et al. Enhanced oral bioavailability of dexibuprofen by a novel solid self-emulsifying drug delivery system (SEDDS). Eur J Pharm Biopharm. 2009;72:539–545.
   PubMed Web of Science ®Google Scholar
• Lia P, Ghosha A, Wagnera RF, et al. Effect of combined use of nonionic surfactant on formation of oil-in-water microemulsions. Int J Pharm. 2005;288:27–34.
   PubMed Web of Science ®Google Scholar
• Mathis GA. Clinical ophthalmic pharmacology: Therapeutics: Ocular drug delivery. In: Gelatt KN, eds. Veterinary Ophthalmology. Orlando: Lippincott Williams & Wilkins;1999:291–297.
   Google Scholar
• Snibson GR. Ocular surface residence times of artificial tear solutions. Cornea. 1992;11(4):288–229.
   PubMed Web of Science ®Google Scholar
• Beyazyıldız E, Acar U, Beyazyıldız Ö. Comparison of prednisolone acetate and loteprednol etabonate for the treatment of benzalkonium chloride-induced dry eye syndrome in rats. J Ocul Pharmacol Ther. 2014;30(4):306–312.
   PubMed Web of Science ®Google Scholar
• Gamal M. Maghraby El. Self-microemulsifying and microemulsion systems for transdermal delivery of indomethacin: Effect of phase transition. Colloids Surf B. 2010;75:595–600.
   PubMed Web of Science ®Google Scholar
• Evilevitch A, Olsson U, Jonsson B, et al. Kinetics of oil solubilization in microemulsion droplets mechanism of oil transport. Langmuir. 2000;16:8755−8762.
   Web of Science ®Google Scholar
• Buyukozturk F, Benneyan JC, Carrier RL. Impact of emulsion-based drug delivery systems on intestinal permeability and drug release kinetics. J Control Release. 2010;142:22–30.
   PubMed Web of Science ®Google Scholar