Advanced search
Publication Cover
Ocular Immunology and Inflammation Volume 27, 2019 - Issue 5
Submit an article Journal homepage
103
Views
5
CrossRef citations to date
0
Altmetric
Original Articles

Increased Lacrimal Fluid Level of HMGB1 in Vernal Keratoconjunctivitis

Roberto CaputoDepartment of Pediatric Ophthalmology, AOU Meyer, Florence, Italy
, MD,
Mattia PastiDepartment of Pediatric Ophthalmology, AOU Meyer, Florence, ItalyCorrespondence[email protected]
, MD,
Cinzia de LiberoDepartment of Allergology, AOU Meyer, Florence, Italy
, MD,
Francesca MoriDepartment of Allergology, AOU Meyer, Florence, Italy
, MD,
Simona BarniDepartment of Allergology, AOU Meyer, Florence, Italy
, MD,
Gioia DantiDepartment of Pediatric Ophthalmology, AOU Meyer, Florence, Italy
, ORTHOPTIST,
Daniela BuonvicinoDepartment of Health Sciences, Clinical Pharmacology Section, Università degli Studi di Firenze, Florence, Italy
, PhD,
Matteo UrruDepartment of Health Sciences, Clinical Pharmacology Section, Università degli Studi di Firenze, Florence, ItalyORCID Iconhttps://orcid.org/0000-0003-3814-8011
, PhDORCID Icon,
Alberto ChiarugiDepartment of Health Sciences, Clinical Pharmacology Section, Università degli Studi di Firenze, Florence, Italy
, MD &
Neri PucciDepartment of Allergology, AOU Meyer, Florence, Italy
, MD show all
Pages 808-812 | Received 15 Jan 2018, Accepted 11 Apr 2018, Published online: 30 May 2018

References

  • Nebbioso M, Zicari AM, Lollobrigida V, Marenco M, Duse M. Assessment of corneal alterations by confocal microscopy in vernal keratoconjunctivitis. Semin Ophthalmol. 2015;30(1):40–43.
  • Goodwin GH, Sanders C, Johns EW. A new group of chromatin-associated proteins with a high content of acidic and basic amino acids. Eur J Biochem. 1973;38(1):14–19.
  • Yu SS, Li HJ, Goodwin GH, Johns EW. Interaction of non-histone chromosomal proteins HMG1 and HMG2 with DNA. Eur J Biochem. 1977;78(2):497–502.
  • Venereau E, Casalgrandi M, Schiraldi M, et al. Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release. J Exp Med. 2012;209(9):1519–1528.
  • Pucci N, Novembre E, Cianferoni A, et al. Efficacy and safety of cyclosporine eyedrops in vernal keratoconjunctivitis. Ann Allergy, Asthma Immunol: off Pub Am Coll Allergy, Asthma, Immunol. 2002;89(3):298–303.
  • Nebbioso M, Zicari AM, Celani C, Lollobrigida V, Grenga R, Duse M. Pathogenesis of vernal keratoconjunctivitis and associated factors. Semin Ophthalmol. 2015;30(5–6):340–344.
  • De Smedt S, Wildner G, Kestelyn P. Vernal keratoconjunctivitis: an update. Br J Ophthalmol. 2013;97(1):9–14.
  • Vichyanond P, Pacharn P, Pleyer U, Leonardi A. Vernal keratoconjunctivitis: a severe allergic eye disease with remodeling changes. Pediatr Allergy Immunology: off Publication Eur Soc Pediatr Allergy Immunol. 2014;25(4):314–322.
  • Leonardi A. Vernal keratoconjunctivitis: pathogenesis and treatment. Prog Retin Eye Res. 2002;21(3):319–339.
  • Leonardi A, Bogacka E, Fauquert JL, et al. Ocular allergy: recognizing and diagnosing hypersensitivity disorders of the ocular surface. Allergy. 2012;67(11):1327–1337.
  • Zicari AM, Nebbioso M, Zicari A, et al. Serum levels of IL-17 in patients with vernal keratoconjunctivitis: a preliminary report. Eur Rev Med Pharmacol Sci. 2013;17(9):1242–1244.
  • Zicari AM, Zicari A, Nebbioso M, et al. High-mobility group box-1 (HMGB-1) and serum soluble receptor for advanced glycation end products (sRAGE) in children affected by vernal keratoconjunctivitis. Pediatr Allergy Immunology: off Publication Eur Soc Pediatr Allergy Immunol. 2014;25(1):57–63.
  • Pachydaki SI, Tari SR, Lee SE, et al. Upregulation of RAGE and its ligands in proliferative retinal disease. Exp Eye Res. 2006;82(5):807–815.
  • Arimura N, Ki IY, Hashiguchi T, Sakamoto T, Maruyama I. High-mobility group box 1 protein in endophthalmitis. Graefe’s Archive for Clin Exp Ophthalmol = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. 2008;246(7):1053–1058.
  • Arimura N, Ki-I Y, Hashiguchi T, et al. Intraocular expression and release of high-mobility group box 1 protein in retinal detachment. Lab Invest. 2009;89(3):278–289.
  • Cavone L, Muzzi M, Mencucci R, et al. 18beta-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis. Ocul Immunol Inflamm. 2011;19(3):180–185.
  • Han SJ, Min HJ, Yoon SC, et al. HMGB1 in the pathogenesis of ultraviolet-induced ocular surface inflammation. Cell Death Dis. 2015;6:e1863.
  • Andersson U, Tracey KJ. HMGB1 is a therapeutic target for sterile inflammation and infection. Annu Rev Immunol. 2011;29:139–162.
  • Musumeci D, Roviello GN, Montesarchio D. An overview on HMGB1 inhibitors as potential therapeutic agents in HMGB1-related pathologies. Pharmacol Ther. 2014;141(3):347–357.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.