Prompt and Sustained Suppression of Intraocular Inflammation with Adalimumab in Pediatric Patients with Non-Infectious Uveitis Resistant to Traditional Managements: A 6-Month Follow-Up Research

References

• Evereklioglu C, Borlu M. Sustained remission after infliximab in a child with vasculitis refractory to conventional immunosuppressives including interferon-alpha. Br J Ophthalmol. 2008;92(1034):1148–1149. doi:10.1136/bjo.2007.127522.
   Google Scholar
• Evereklioglu C, Er H, Türköz Y, Cekmen M. Serum levels of TNF-alpha, sIL-2R, IL-6, and IL-8 are increased and associated with elevated lipid peroxidation in patients with Behçet’s disease. Mediators Inflamm. 2002;11(2):87–93. doi:10.1080/09629350220131935.
   PubMed Web of Science ®Google Scholar
• Siiskonen M, Hirn I, Pesälä R, Hautala T, Ohtonen P, Hautala N. Prevalence, incidence and epidemiology of childhood uveitis. Acta Ophthalmol. 2021;99(2):e160–e3. doi:10.1111/aos.14535.
   PubMed Web of Science ®Google Scholar
• Norcia LF, Kiappe OP, Jorge EC. Biological therapy in noninfectious pediatric uveitis: a systematic review. Clin Ophthalmol. 2021;15:3765–3776. doi:10.2147/OPTH.S322445.
   PubMed Web of Science ®Google Scholar
• Borlu M, Ukşal U, Ferahbaş A, Evereklioglu C. Clinical features of Behçet’s disease in children. Int J Dermatol. 2006;45(6):713–716. doi:10.1111/j.1365-4632.2006.02754.x.
   PubMed Web of Science ®Google Scholar
• Yalçındağ FN, Güngör SG, Değirmenci MFK, et al. The clinical characteristics of pediatric non-infectious uveitis in two tertiary referral centers in Turkey. Ocul Immunol Inflamm. 2021;29(2):282–289. doi:10.1080/09273948.2019.1674890.
   PubMed Web of Science ®Google Scholar
• Cunningham ET Jr. Uveitis in children. Ocul Immunol Inflamm. 2000;8(4):251–261. doi:10.1076/ocii.8.4.251.6459.
   PubMed Web of Science ®Google Scholar
• Lam L, Lowder JY, Baerveldt G, Smith SD, Traboulsi EI. Surgical management of cataracts in children with juvenile rheumatoid arthritis associated uveitis. Am J Ophthalmol. 2003;135(6):772–778. doi:10.1016/S0002-9394(03)00123-5.
   PubMed Web of Science ®Google Scholar
• Kouwenberg CV, Koopman-Kalinina Ayuso V, de Boer JH. Clinical benefits and potential risks of Adalimumab in non-JIA chronic paediatric uveitis. Acta Ophthalmol. 2021;100(4):e994–e1001. doi:10.1111/aos.15012.
   PubMed Web of Science ®Google Scholar
• Evereklioglu C. Current concepts in the etiology and treatment of Behçet disease. Surv Ophthalmol. 2005;50(4):297–350. doi:10.1016/j.survophthal.2005.04.009.
   PubMed Web of Science ®Google Scholar
• Sood AB, Angeles-Han ST. An update on treatment of pediatric chronic non-infectious uveitis. Curr Treatm Opt Rheumatol. 2017;3(1):1–16.doi:10.1007/s40674-017-0057-z.
   PubMedGoogle Scholar
• Evereklioglu C. Ocular Behçet disease: current therapeutic approaches. Curr Opin Ophthalmol. 2011;22(6):508–516. doi:10.1097/ICU.0b013e32834bbe91.
   PubMed Web of Science ®Google Scholar
• Evereklioglu C. Managing the symptoms of Behçet’s disease. Expert Opin Pharmacother. 2004;5(2):317–328. doi:10.1517/14656566.5.2.317.
   PubMed Web of Science ®Google Scholar
• Jaffe GJ, Dick AD, Brézin AP, et al. Adalimumab in patients with active noninfectious uveitis. N Engl J Med. 2016;375(10):932–943. doi:10.1056/NEJMoa1509852.
   PubMed Web of Science ®Google Scholar
• Jabs DA, Nussenblatt RB, Rosenbaum JT, Standardization of Uveitis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data: results of the first international workshop. Am J Ophthalmol. 2005;140:509–516.
   PubMed Web of Science ®Google Scholar
• Nussenblatt RB, Palestine AG, Chan CC, Roberge F. Standardization of vitreal inflammatory activity in intermediate and posterior uveitis. Ophthalmology. 1985;92(4):467–471. doi:10.1016/S0161-6420(85)34001-0.
   PubMed Web of Science ®Google Scholar
• Onel KB, Horton DB, Lovell DJ, et al. 2021 american college of rheumatology guideline for the treatment of juvenile idiopathic arthritis: recommendations for nonpharmacologic therapies, medication monitoring, immunizations, and imaging. Arthritis Care Res (Hoboken). 2022;74(4):505–520. doi:10.1002/acr.24839.
   PubMed Web of Science ®Google Scholar
• Ucan Gunduz G, Yalcinbayir O, Cekic S, et al. Anti-Tumor necrosis factor treatment in the management of pediatric noninfectious uveitis: infliximab versus Adalimumab. J Ocul Pharmacol Ther. 2021;37(4):236–240. doi:10.1089/jop.2020.0081.
   PubMed Web of Science ®Google Scholar
• Quartier P, Baptiste A, Despert V, et al,ADJUVITE Study Group. ADJUVITE: a double-blind, randomised, placebo-controlled trial of Adalimumab in early onset, chronic, juvenile idiopathic arthritis-associated anterior uveitis. Ann Rheum Dis. 2018;77(7):1003–1011. doi:10.1136/annrheumdis-2017-212089.
   PubMed Web of Science ®Google Scholar
• Fabiani C, Vitale A, Emmi G, et al. Efficacy and safety of Adalimumab in Behçet’s disease-related uveitis: a multicenter retrospective observational study. Clin Rheumatol. 2017;36(1):183–189. doi:10.1007/s10067-016-3480-x.
   PubMed Web of Science ®Google Scholar
• Ho M, Chen LJ, Sin HPY, et al. Experience of using Adalimumab in treating sight-threatening paediatric or adolescent Behcet’s disease-related uveitis. J Ophthalmic Inflamm Infect. 2019;9(1):14. doi:10.1186/s12348-019-0181-z.
   PubMedGoogle Scholar
• Lee JT, Yates WB, Rogers S, et al. Adalimumab for the treatment of refractory active and inactive non-infectious uveitis. Br J Ophthalmol. 2018;102(12):1672–1678. doi:10.1136/bjophthalmol-2017-311234.
   PubMed Web of Science ®Google Scholar
• Díaz-Llopis M, Salom D, Garcia-de-Vicuña C, et al. Treatment of refractory uveitis with Adalimumab: a prospective multicenter study of 131 patients. Ophthalmology. 2012;119(8):1575–1581. doi:10.1016/j.ophtha.2012.02.018.
   PubMed Web of Science ®Google Scholar
• Calvo-Río V, Blanco R, Beltrán E, et al. Anti-TNF-α therapy in patients with refractory uveitis due to Behçet’s disease: a 1-year follow-up study of 124 patients. Rheumatology (Oxford). 2014;53(12):2223–2231. doi:10.1093/rheumatology/keu266.
   PubMed Web of Science ®Google Scholar