Advanced search
Publication Cover
Ocular Immunology and Inflammation Latest Articles
Submit an article Journal homepage
19
Views
0
CrossRef citations to date
0
Altmetric
Original Article

Evaluation of Meibomian Gland Structure and Function in Patients with Vernal Keratoconjunctivitis Using Non Contact Meibography and Lipid Layer Interferometry

Parshant SinglaAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, IndiaView further author information
, MS,
Chintan MalhotraAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, IndiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-7145-4654View further author information
, MSORCID Icon,
Arun K. JainAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, IndiaView further author information
, MD, DNB,
Amit GuptaAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, IndiaView further author information
, MS &
Jagat RamAdvanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, IndiaView further author information
, MS
Received 19 Jan 2024, Accepted 22 Jun 2024, Published online: 10 Jul 2024

References

  • Leonardi A, Dominicis C, Motterle L. Immunopathogenesis of ocular allergy: A schematic approach to different clinical entities. Curr Opin Allergy Clin Immunol. 2007;7(5):429–435. doi:10.1097/ACI.0b013e3282ef8674.
  • Leonardi A. Management of vernal keratoconjunctivitis. Ophthalmol Ther. 2013;2(2):73–88. doi:10.1007/s40123-013-0019-y.
  • Tuft SJ, Dart JK, Kemeny M. Limbal vernal keratoconjunctivitis: clinical characteristics and immunoglobulin E expression compared with palpebral vernal. Eye (Lond). 1989;3(4):420–427. doi:10.1038/eye.1989.63.
  • Kumar S. Vernal keratoconjunctivitis: a major review. Acta Ophthalmol. 2009;87(2):133–147. doi:10.1111/j.1755-3768.2008.01347.x.
  • Stapleton F, Alves M, Bunya VY, Jalbert I, Lekhanont K, Malet F, et al. TFOS DEWS II epidemiology report. Ocul Surf. 2017;15(3):334–365. doi:10.1016/j.jtos.2017.05.003.
  • Hu Y, Matsumoto Y, Dogru M, Okada N, Igarashi A, Fukagawa K, et al. The differences of tear function and ocular surface findings in patients with atopic keratoconjunctivitis and vernal keratoconjunctivitis. Allergy. 2007;62(8):917–925. doi:10.1111/j.1398-9995.2007.01414.x.
  • Ibrahim OMA, Matsumoto Y, Dogru M, Adan ES, Wakamatsu TH, Shimazaki J, et al. In vivo confocal microscopy evaluation of meibomian gland dysfunction in atopic- keratoconjunctivitis patients. Ophthalmology. 2012;119(10):1961–1968. doi:10.1016/j.ophtha.2012.04.001.
  • Wei Q, Le Q, Hong J, Xiang J, Wei A, Xu J. In vivo confocal microscopy of meibomian glands and palpebral conjunctiva in vernal keratoconjunctivitis. Indian J Ophthalmol. 2015;63(4):327–330. doi:10.4103/0301-4738.158073.
  • Arita R. Meibography: A Japanese perspective. Invest Ophthalmol Vis Sci. November 27, 2018;59(14):DES48. doi:10.1167/iovs.17-23631.
  • Schmidl D, Schlatter A, Chua J, Tan B, Garhöfer G, Schmetterer L. Novel approaches for imaging-based diagnosis of ocular surface disease. Diagnostics. August 13, 2020;10(8):589. doi:10.3390/diagnostics10080589.
  • Bonini S, Sacchetti M, Mantelli F, Lambiase A. Clinical grading of vernal keratoconjunctivitis. Curr Opin Allergy Clin Immunol. 2007;7(5):436–441. doi:10.1097/ACI.0b013e3282efb726.
  • Machalinska A, Zakrzewska A, Safranow K, Wiszniewska B, Machaliński B. Risk factors and symptoms of meibomian gland loss in a healthy population. J Ophthalmol. 2016;2016:1–8. doi:10.1155/2016/7526120.
  • Daniel E, Maguire MG, Pistilli M, Bunya VY, Massaro-Giordano GM, Smith E, et al. Grading and baseline characteristics of meibomian glands in meibography images and their clinical associations in the Dry Eye Assessment and Management (DREAM) study. Ocul Surf. 2019;17(3):491–501. doi:10.1016/j.jtos.2019.04.003.
  • Park J, Kim J, Lee H, Park M, Baek S. Functional and structural evaluation of the meibomian gland using a LipiView interferometer in thyroid eye disease. Can J Ophthalmol. 2018;53(4):373–379. doi:10.1016/j.jcjo.2017.11.006.
  • Bron AJ, Evans VE, Smith JA. Grading of corneal and conjunctival staining in the context of other dry eye tests. Cornea. 2003;22(7):640–650. doi:10.1097/00003226-200310000-00008.
  • Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33(1):159–174. doi:10.2307/2529310.
  • Yang B, Wen K, Li J, Zhang S, Fan Z, Liang X, et al. Quantitative evaluation of lipid layer thickness and blinking in children with allergic conjunctivitis. Graefes Arch Clin Exp Ophthalmol. 2021;18:112–118.
  • Gupta S, Rahman M, Tibrewal S, Gaur A, Ganesh S, Sangwan VS. Evaluation of dry eyes in children with vernal kerato-conjunctivitis using clinical tests and ocular surface analysis. Indian J Ophthalmol. April, 2023;71(4):1488–1494. doi:10.4103/IJO.IJO_2836_22.
  • Dogru M, Gunay M, Celik G, Aktas A. Evaluation of the tear film instability in children with allergic diseases. Cutan Ocul Toxicol. 2016;35(1):49–52. doi:10.3109/15569527.2015.1010727.
  • Akil H, Celik F, Ulas F, Kara IS. Dry eye syndrome and allergic conjunctivitis in the pediatric population. Middle East Afr J Ophthalmol. 2015;22(4):467–471. doi:10.4103/0974-9233.167814.
  • Chen L, Pi L, Fang J, Chen X, Ke N, Liu Q. High incidence of dry eye in young children with allergic conjunctivitis in Southwest China. Acta Ophthalmol. 2016;94(8):e727–30. doi:10.1111/aos.13093.
  • Arita R, Itoh K, Maeda S, Maeda K, Furuta A, Tomidokoro A, et al. Meibomian gland duct distortion in patients with perennial allergic conjunctivitis. Cornea. 2010;29(8):858–860. doi:10.1097/ICO.0b013e3181ca3668.
  • Hirota M, Uozato H, Kawamorita T, Shibata Y, Yamamoto S. Effect of incomplete blinking on tear film stability. Optom Vis Sci. 2013;90(7):650–657. doi:10.1097/OPX.0b013e31829962ec.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.