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Articles

Incorporation of DNA/PEI polyplexes into gelatin/chitosan hydrogel scaffolds: a μ-DSC study

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Pages 1-11 | Received 02 Jan 2017, Accepted 02 Mar 2017, Published online: 28 Mar 2017

References

  • Giacca M. Virus –mediated gene transfer to induce therapeutic angiogenesis: where do we stand? Int J Nanomed. 2007;2:527–540.
  • Ma B, Zhang S, Jiang H, et al. Lipoplex morphologies and their influences on transfection efficiency in gene delivery. J Controlled Release. 2007;123:184–194.10.1016/j.jconrel.2007.08.022
  • Boussif O, Lezoualch F, Zanta MA, et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Nat Acad Sci. 1995;92:7297–7301.10.1073/pnas.92.16.7297
  • Akinc A, Thomas M, Klibanov AM, et al. Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis. J Gene Med. 2005;7:657–663.10.1002/(ISSN)1521-2254
  • Bieber T, Meissner W, Kostin S, et al. Intracellular route and transcriptional competence of polyethylenimine-mediated DNA complexes. J Controlled Release. 2002;82:441–454.10.1016/S0168-3659(02)00129-3
  • Brunot C, Ponsonnet L, Lagneau C, et al. Cytotoxicity of polyethyleneimine (PEI), precursor base layer of polyelectrolyte multiplayer films. Biomaterials. 2007;28:632–640.10.1016/j.biomaterials.2006.09.026
  • Mady MM, Mohammed WA, El-Guendy NM, et al. Effect of polymer molecular weight on the DNA/PEI polyplexes properties. Romanian J Biophys. 2011;2:151–165.
  • Chen X-A, Zhang L-J, He Z-J, et al. Plasmid-encapsulated polyethylene glycol-grafted polyethyleneimine nanoparticles for gene delivery into rat mesenchymal stem cells. Int J Nanomed. 2011;6:843–853.
  • Tang GP, Zeng JM, Gao SJ, et al. Polyethylene glycol modified polyethyleneimine for improved CNS gene transfer: effect of PEGylation extent. Biomaterials. 2003;24:2351–2362.10.1016/S0142-9612(03)00029-2
  • Höbel S, Loos A, Appelhans D, et al. Maltose- and maltotriose-modified, hyperbranched poly(ethylene imine)s (OM-PEIs): physicochemical and biological properties of DNA and siRNA complexes. J Controlled Release. 2011;149:146–158.10.1016/j.jconrel.2010.10.008
  • Gutsch D, Appelhans D, Höbel S, et al. Biocompatibility and efficacy of oligomaltose-grafted low-molecular weight PEIs (OM-PEIs) for in vivo gene delivery. Mol Pharm. 2013;10(12):4666–4675.10.1021/mp400479g
  • Schallon A, Synatschke CV, Pergushov V, et al. DNA melting temperature assay for assessing the stability of DNA polyplexes intended for nonviral gene delivery. Langmuir. 2011;27:12042–12051.10.1021/la201803c
  • Rumschöttel J, Kosmella S, Prietzel C, et al. Change in size, morphology and stability of DNA polyplexes with hyperbranched poly(ethyleneimines) containing bulky maltose units. Colloids Surf B. 2016;138:78–85.10.1016/j.colsurfb.2015.11.061
  • Lei Y, Huang S, Sharif-Kashani P, et al. Incorporation of active DNA/cationic polymer polyplexes into hydrogel scaffolds. Biomaterials. 2010;31:9106–9116.10.1016/j.biomaterials.2010.08.016
  • Kovach I, Rumschöttel J, Friberg SE, et al. Janus emulsion mediated porous scaffold bio-fabrication. Colloids Surf B. 2016;145:347–352.10.1016/j.colsurfb.2016.05.018
  • Appelhans D, Komber H, Quadir MA, et al. Hyperbranched PEI with various oligosaccharide architectures: synthesis, characterization, ATP complexation, and cellular uptake properties. Biomacromolecules. 2009;10:1114–1124.10.1021/bm801310d
  • Duguid JG, Bloomfield VA, Benevides JM, et al. DNA melting investigated by differential scanning calorimetry and Raman spectroscopy. Biophysics. 1996;71:3350–3360.
  • Bigi A, Cojazzi G, Panzavolta S, et al. Mechanical and thermal properties of gelatin films at different degrees of glutaraldehyde crosslinking. Biomaterials. 2001;22:763–768.
  • Tauhardt L, Kempe K, Knop K, et al. Linear polyethyleneimine: optimized synthesis and characterization – on the way to “pharmagrade” batches. Macromol Chem Phys. 2011;212:1918–1924.
  • Kötz J, Köpke H, Schmidt-Naake G, et al. Polyanion-polycation complex formation as a function of the position of the functional groups. Polymer. 1996;37:2775–2781.10.1016/0032-3861(96)87641-5
  • Kovach I, Won J, Friberg SE, et al. Completely engulfed olive/silicone oil Janus emulsions with gelatin and chitosan. Colloid Polym Sci. 2016;294:705–713.10.1007/s00396-016-3828-4
  • Rinaudo M, Domard A. In: Skjak-Braek G, Anthonson T, Sandford P, editors. Chitin and chitosan: sources, chemistry, biochemistry, physical properties, and applications. London: Elsevier Applied Science; 1989. p. 71–86.

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